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Therapeutic Area
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CARDIOVASCULAR (45)
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DERMATOLOGY (31)
DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
Level 2
Level 3
Level 4
Level 5
Level 6
Active Pharmaceutical Ingredients (APIs)
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
10647
GSK-249320
2
Antibody
Investigational
Unknown
Unknown
Stroke
Myelin-associated glycoprotein inhibitor
GSK-249320
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ORM-12741
2
Small molecule
Investigational
Unknown
Unknown
Alzheimer Disease
Unknown
ORM-12741
×
Maximum Phase:
2
First Approval:
None
UNII:
D26C95A960
Molecule Type:
Small molecule
Molecular Formula:
C18H23NO2
Molecular Weight:
285.39
AlogP:
3.78
PSA:
25.61
HBD:
0.0
HBA:
#RotB:
2.0
Source:
IBUDILAST
2
Small molecule
Investigational
Unknown
Unknown
Diabetic Neuropathies; Glioblastoma; Migraine Disorders; Pain; Substance-Related Disorders; Alcoholism; Amphetamine-Related Disorders; Amyotrophic Lateral Sclerosis; Multiple Sclerosis, Chronic Progressive; Opioid-Related Disorders; Pneumonia, Viral; Lung Diseases, Obstructive; Spinal Cord Diseases
Phosphodiesterase 10A inhibitor
IBUDILAST
×
Maximum Phase:
2
First Approval:
None
UNII:
M0TTH61XC5
Molecule Type:
Small molecule
Molecular Formula:
C14H18N2O
Molecular Weight:
230.31
AlogP:
3.3
PSA:
34.37
HBD:
0.0
HBA:
#RotB:
3.0
Source:
NAVOCAFTOR
2
Small molecule
Investigational
Unknown
Unknown
Cystic Fibrosis
Unknown
NAVOCAFTOR
×
Maximum Phase:
2
First Approval:
None
UNII:
W2F2XU189O
Molecule Type:
Small molecule
Molecular Formula:
C15H11F3N4O5S
Molecular Weight:
416.34
AlogP:
1.94
PSA:
141.43
HBD:
2.0
HBA:
#RotB:
5.0
Source:
4-DEMETHYL-4-CHOLESTERYLOXYCARBONYLPENCLOMEDINE
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms
DNA disrupting agent
4-DEMETHYL-4-CHOLESTERYLOXYCARBONYLPENCLOMEDINE
×
Maximum Phase:
2
First Approval:
None
UNII:
1S83F4T2WE
Molecule Type:
Small molecule
Molecular Formula:
C35H48Cl5NO4
Molecular Weight:
724.04
AlogP:
12.15
PSA:
57.65
HBD:
0.0
HBA:
#RotB:
8.0
Source:
POLY-ICLC
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
POLY-ICLC
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
OCTENIDINE
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Antiseptic
OCTENIDINE
×
Maximum Phase:
2
First Approval:
None
UNII:
OZE0372S5A
Molecule Type:
Small molecule
Molecular Formula:
C36H62N4
Molecular Weight:
550.92
AlogP:
9.63
PSA:
34.58
HBD:
0.0
HBA:
#RotB:
25.0
Source:
WNT-974
2
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Squamous Cell
Probable protein-cysteine N-palmitoyltransferase porcupine inhibitor
WNT-974
×
Maximum Phase:
2
First Approval:
None
UNII:
U27F40013Q
Molecule Type:
Small molecule
Molecular Formula:
C23H20N6O
Molecular Weight:
396.45
AlogP:
3.79
PSA:
93.55
HBD:
1.0
HBA:
#RotB:
5.0
Source:
CALCITONIN EEL
2
Protein
Investigational
Unknown
Unknown
Hemiplegia
Unknown
CALCITONIN EEL
×
Maximum Phase:
2
First Approval:
None
UNII:
R5527T0R0U
Molecule Type:
Protein
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GW-274150
2
Small molecule
Investigational
Unknown
Unknown
Asthma; Arthritis, Rheumatoid; Migraine Disorders
Nitric oxide synthase, inducible inhibitor
GW-274150
×
Maximum Phase:
2
First Approval:
None
UNII:
0ZZF1V8G63
Molecule Type:
Small molecule
Molecular Formula:
C8H17N3O2S
Molecular Weight:
219.31
AlogP:
0.11
PSA:
99.2
HBD:
4.0
HBA:
#RotB:
7.0
Source:
BATEFENTEROL
2
Small molecule
Investigational
Unknown
Unknown
Pulmonary Disease, Chronic Obstructive
Beta-2 adrenergic receptor agonist
BATEFENTEROL
×
Maximum Phase:
2
First Approval:
None
UNII:
1IAT42T80T
Molecule Type:
Small molecule
Molecular Formula:
C40H42ClN5O7
Molecular Weight:
740.26
AlogP:
6.43
PSA:
165.25
HBD:
6.0
HBA:
#RotB:
13.0
Source:
LY-2090314
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Pancreatic Neoplasms; Leukemia
Glycogen synthase kinase-3 alpha inhibitor
LY-2090314
×
Maximum Phase:
2
First Approval:
None
UNII:
822M3GYM67
Molecule Type:
Small molecule
Molecular Formula:
C28H25FN6O3
Molecular Weight:
512.55
AlogP:
3.42
PSA:
91.95
HBD:
1.0
HBA:
#RotB:
2.0
Source:
VIPIVOTIDE TETRAXETAN GALLIUM
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
VIPIVOTIDE TETRAXETAN GALLIUM
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C49H68GaN9O16
Molecular Weight:
1108.85
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
VESTIPITANT MESYLATE
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Neurokinin 1 receptor antagonist
VESTIPITANT MESYLATE
×
Maximum Phase:
2
First Approval:
None
UNII:
OWR424W90Q
Molecule Type:
Small molecule
Molecular Formula:
C24H28F7N3O4S
Molecular Weight:
587.56
AlogP:
5.93
PSA:
35.58
HBD:
1.0
HBA:
#RotB:
3.0
Source:
TCH346
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
TCH346
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GIMSILUMAB
2
Antibody
Investigational
Unknown
Unknown
Arthritis, Rheumatoid; Severe Acute Respiratory Syndrome
Granulocyte-macrophage colony-stimulating factor inhibitor
GIMSILUMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
8961SFA7R3
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
VIPIVOTIDE TETRAXETAN GALLIUM GA-68
2
Small molecule
Investigational
Unknown
Unknown
Prostatic Neoplasms, Castration-Resistant
Unknown
VIPIVOTIDE TETRAXETAN GALLIUM GA-68
×
Maximum Phase:
2
First Approval:
None
UNII:
7P5C02S4X8
Molecule Type:
Small molecule
Molecular Formula:
C49H68GaN9O16
Molecular Weight:
1107.06
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
SOTB07
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
SOTB07
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
9-AMINOCAMPTOTHECIN
2
Small molecule
Investigational
Unknown
Unknown
Leukemia, Myeloid, Acute; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Esophageal Neoplasms; Kidney Neoplasms; Lung Neoplasms; Lymphoma; Ovarian Neoplasms; Peritoneal Neoplasms; Stomach Neoplasms
Unknown
9-AMINOCAMPTOTHECIN
×
Maximum Phase:
2
First Approval:
None
UNII:
5MB77ICE2Q
Molecule Type:
Small molecule
Molecular Formula:
C20H17N3O4
Molecular Weight:
363.37
AlogP:
1.66
PSA:
107.44
HBD:
2.0
HBA:
#RotB:
1.0
Source:
F901318
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
F901318
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ROSTAFUROXIN
2
Small molecule
Investigational
Unknown
Unknown
Essential Hypertension; Hypertension
Unknown
ROSTAFUROXIN
×
Maximum Phase:
2
First Approval:
None
UNII:
P848LCX62B
Molecule Type:
Small molecule
Molecular Formula:
C23H34O4
Molecular Weight:
374.52
AlogP:
3.99
PSA:
73.83
HBD:
3.0
HBA:
#RotB:
1.0
Source:
INODIFTAGENE VIXTEPLASMID
2
Gene
Investigational
Unknown
Unknown
Urinary Bladder Neoplasms
Unknown
INODIFTAGENE VIXTEPLASMID
×
Maximum Phase:
2
First Approval:
None
UNII:
98YK326XZ6
Molecule Type:
Gene
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
DOCIPARSTAT SODIUM
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
DOCIPARSTAT SODIUM
×
Maximum Phase:
2
First Approval:
None
UNII:
4O75889WF4
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ACETIC ACID C-11
2
Small molecule
Investigational
Unknown
Unknown
Prostatic Neoplasms, Castration-Resistant; Carcinoma, Hepatocellular
Unknown
ACETIC ACID C-11
×
Maximum Phase:
2
First Approval:
None
UNII:
2A9OM7IPNW
Molecule Type:
Small molecule
Molecular Formula:
C2H4O2
Molecular Weight:
59.05
AlogP:
0.09
PSA:
37.3
HBD:
1.0
HBA:
#RotB:
0.0
Source:
INCLACUMAB
2
Antibody
Investigational
Unknown
Unknown
Peripheral Arterial Disease; Coronary Disease; Myocardial Infarction
P-selectin antagonist
INCLACUMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
A6734I702L
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
POLYDEXTROSE
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
POLYDEXTROSE
×
Maximum Phase:
2
First Approval:
None
UNII:
VH2XOU12IE
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PRS-211375
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Cannabinoid CB2 receptor agonist
PRS-211375
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TAK-448
2
Small molecule
Investigational
Unknown
Unknown
Prostatic Neoplasms; Hypogonadism
Unknown
TAK-448
×
Maximum Phase:
2
First Approval:
None
UNII:
YO029HR229
Molecule Type:
Small molecule
Molecular Formula:
C58H80N16O14
Molecular Weight:
1225.38
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
LAPACHONE
2
Small molecule
Investigational
Unknown
Unknown
Carcinoma; Neoplasms
Unknown
LAPACHONE
×
Maximum Phase:
2
First Approval:
None
UNII:
6N4FA2QQ6A
Molecule Type:
Small molecule
Molecular Formula:
C15H14O3
Molecular Weight:
242.27
AlogP:
2.75
PSA:
43.37
HBD:
0.0
HBA:
#RotB:
0.0
Source:
CTS-1027
2
Small molecule
Investigational
Unknown
Unknown
Hepatitis C; Hepatitis C, Chronic
Unknown
CTS-1027
×
Maximum Phase:
2
First Approval:
None
UNII:
2QD3F58224
Molecule Type:
Small molecule
Molecular Formula:
C19H20ClNO6S
Molecular Weight:
425.89
AlogP:
3.21
PSA:
101.93
HBD:
2.0
HBA:
#RotB:
6.0
Source:
REVAPRAZAN
2
Small molecule
Investigational
Unknown
Unknown
Gastroesophageal Reflux
Unknown
REVAPRAZAN
×
Maximum Phase:
2
First Approval:
None
UNII:
5P184180P5
Molecule Type:
Small molecule
Molecular Formula:
C22H23FN4
Molecular Weight:
362.45
AlogP:
5.1
PSA:
41.05
HBD:
1.0
HBA:
#RotB:
3.0
Source:
MIVAVOTINIB CITRATE
2
Small molecule
Investigational
Unknown
Unknown
Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Ovarian Neoplasms; Lymphoma, Large B-Cell, Diffuse
Tyrosine-protein kinase SYK inhibitor
MIVAVOTINIB CITRATE
×
Maximum Phase:
2
First Approval:
None
UNII:
6ZJ8V3Q0H1
Molecule Type:
Small molecule
Molecular Formula:
C23H29FN6O8
Molecular Weight:
536.52
AlogP:
1.55
PSA:
97.86
HBD:
3.0
HBA:
#RotB:
3.0
Source:
MIBAMPATOR
2
Small molecule
Investigational
Unknown
Unknown
Alzheimer Disease
Glutamate receptor ionotropic AMPA positive allosteric modulator
MIBAMPATOR
×
Maximum Phase:
2
First Approval:
None
UNII:
A9V5BW73UU
Molecule Type:
Small molecule
Molecular Formula:
C21H30N2O4S2
Molecular Weight:
438.62
AlogP:
2.88
PSA:
92.34
HBD:
2.0
HBA:
#RotB:
10.0
Source:
TESETAXEL
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Melanoma; Prostatic Neoplasms, Castration-Resistant; Stomach Neoplasms; Breast Neoplasms
Unknown
TESETAXEL
×
Maximum Phase:
2
First Approval:
None
UNII:
UG97LO5M8Y
Molecule Type:
Small molecule
Molecular Formula:
C46H60FN3O13
Molecular Weight:
881.99
AlogP:
4.56
PSA:
201.51
HBD:
3.0
HBA:
#RotB:
10.0
Source:
HP184
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
HP184
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
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Compound Name
Maximum Phase
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Compound Properties
Molecular Formula
Molecular Weight
ALogP
PSA