Display Options:
Total: 6532
Small molecule
Approved
OTHER
INJECTION
Obesity
Estrogen receptor alpha agonist
Small molecule
Approved
OTHER
ORAL
Unknown
Adrenergic receptor alpha-1 antagonist
Small molecule
Approved
OTHER
ORAL
Unknown
Bacterial penicillin-binding protein inhibitor
Small molecule
Approved
Unknown
Unknown
Lung Diseases, Obstructive
Unknown
Small molecule
Approved
Unknown
Unknown
Dry Eye Syndromes; Eye Manifestations; Nasal Obstruction
Unknown
Small molecule
Approved
Unknown
Unknown
Hypotension, Orthostatic; Orthostatic Intolerance; Gastrointestinal Hemorrhage; Hyperemesis Gravidarum; Hypoglycemia; Intestinal Obstruction; Myelodysplastic Syndromes; Pain; Wounds and Injuries; Gastroenteritis; Gastroparesis; Gastroschisis; Headache; HIV Infections; Migraine Disorders; Nausea; Neoplasms; Sepsis; Vomiting; Digestive System Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Pain
Unknown
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Psychotic Disorders
Dopamine D2 receptor antagonist
Small molecule
Approved
Unknown
Unknown
Cardiovascular Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Hematologic Neoplasms; Leukemia, Biphenotypic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Polycythemia Vera; Primary Myelofibrosis; Thrombocythemia, Essential; Anemia, Refractory; Leukemia, Myeloid; Myelodysplastic Syndromes; Hepatitis B, Chronic; Leukemia; Lymphoma, Non-Hodgkin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency, Chronic; Sarcoma, Kaposi; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Neoplasms
DNA inhibitor
Small molecule
Approved
OTHER
TOPICAL
Unknown
Glucocorticoid receptor agonist
Small molecule
Approved
EYE; OTHER
OPHTHALMIC
Rectal Neoplasms; Breast Neoplasms; Cholangiocarcinoma; Esophageal Neoplasms; Colorectal Neoplasms; Eye Infections; Herpes Simplex; Keratoconjunctivitis; Neoplasms
DNA inhibitor
Small molecule
Approved
Unknown
Unknown
Ischemic Stroke; Cardiovascular Diseases
Unknown
Small molecule
Approved
OTHER
ORAL
Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Neoplasms
Cytochrome P450 11A1 inhibitor
Small molecule
Approved
Unknown
Unknown
Glaucoma
Unknown
Small molecule
Approved
OTHER
ORAL
Helminthiasis
DNA inhibitor
Small molecule
Approved
Unknown
Unknown
Osteomyelitis; Bacterial Infections
Unknown
Small molecule
Unknown
Unknown
Unknown
Arthralgia; Myalgia; Rheumatic Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
OTHER
ORAL
Depressive Disorder
Dopamine receptor antagonist
Small molecule
Approved
Unknown
Unknown
Brain Neoplasms; Glioblastoma; Anxiety; Dementia; Schizophrenia; Depressive Disorder
Unknown
Small molecule
Approved
OTHER
ORAL
Arthralgia; Myalgia; Rheumatic Diseases
Cyclooxygenase inhibitor
Small molecule
Approved
Unknown
Unknown
Rheumatic Diseases
Unknown
Small molecule
Approved
OTHER
ORAL
Osteomyelitis; Bacterial Infections
Bacterial DNA gyrase inhibitor
Small molecule
Approved
OTHER
ORAL
Acute Kidney Injury; Severe Acute Respiratory Syndrome; Sleep Apnea, Obstructive; Vitamin D Deficiency; Myocardial Infarction; Hyperparathyroidism, Secondary; Parathyroid Diseases; Renal Insufficiency, Chronic
Vitamin D receptor agonist
Small molecule
Approved
Unknown
Unknown
Hypotension, Orthostatic; Orthostatic Intolerance; Depressive Disorder; Hypotension; Myocardial Infarction; Hypertension
Unknown
Small molecule
Approved
Unknown
Unknown
Hemorrhage; Crohn Disease; Diabetes Mellitus, Type 2; Hodgkin Disease; Ischemic Stroke; Osteoarthritis, Knee; Respiratory Syncytial Virus Infections; Substance-Related Disorders; Arrhythmias, Cardiac; Epilepsies, Myoclonic; Pain; Severe Acute Respiratory Syndrome; Atrial Fibrillation; Bipolar Disorder; Diabetes Mellitus, Type 1; Heart Failure; Cardiovascular Diseases
Unknown
Small molecule
Approved
OTHER
INJECTION; TOPICAL
Leukemia; Myopia; Neoplasm Metastasis; Renal Insufficiency, Chronic; Urethral Stricture; Appendiceal Neoplasms; Biliary Tract Neoplasms; Carcinoma, Squamous Cell; Cholangiocarcinoma; Cholangitis, Sclerosing; Corneal Opacity; Esophageal Stenosis; Glaucoma, Neovascular; Glaucoma, Open-Angle; Keratoconus; Liver Neoplasms; Pterygium; Sarcoma; Anus Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma in Situ; Carcinoma, Non-Small-Cell Lung; Carcinoma, Transitional Cell; Colorectal Neoplasms; Head and Neck Neoplasms; Lung Neoplasms; Mesothelioma; Nasopharyngeal Neoplasms; Pancreatic Neoplasms; Stomach Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Adenocarcinoma; Glaucoma; Neoplasms
DNA inhibitor
Small molecule
Approved
IMMUNE SYSTEM; OTHER
ORAL; TOPICAL
Glioblastoma; Insulin Resistance; Alzheimer Disease; Asthma; Diabetes Mellitus, Type 2; Erectile Dysfunction; Essential Hypertension; Gastroparesis; Hepatitis C; Immune System Diseases; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, Non-Hodgkin; Melanoma; Multiple Sclerosis; Nausea; Neuroblastoma; Osteoporosis; Premature Birth; Pulmonary Disease, Chronic Obstructive; Breast Neoplasms; Burns; Hypogonadism; Neoplasms; Prostatic Neoplasms; Psoriasis; Acne Vulgaris; Candidiasis, Vulvovaginal; Dermatitis; Prostatic Neoplasms, Castration-Resistant; Respiratory Distress Syndrome; Vaginosis, Bacterial; Adrenal Gland Diseases; Blastomycosis; Dermatitis, Seborrheic; Onychomycosis; Tinea; Tinea Pedis
Cytochrome P450 51 inhibitor
Small molecule
Approved
OTHER
ORAL
Anxiety; Dementia; Depressive Disorder; Pulmonary Disease, Chronic Obstructive; Schizophrenia; Sleep Initiation and Maintenance Disorders
GABA-A receptor; anion channel positive allosteric modulator
Small molecule
Approved
OTHER
ORAL
Multiple Sclerosis; Sunburn; Angioedema; Conjunctivitis, Allergic; Hypersensitivity; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Rhinitis, Vasomotor; Urticaria
Histamine H1 receptor antagonist
Small molecule
Approved
CARDIOVASCULAR; GASTROINTESTINAL; OTHER
INJECTION; INTRA-ANAL; SUBLINGUAL; TRANSDERMAL
Colorectal Neoplasms; Hypotension; Peripheral Arterial Disease; Hypertension, Pulmonary; Infections; Inflammation; Phlebitis; Rectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Diabetic Neuropathies; Erectile Dysfunction; Hot Flashes; Lung Neoplasms; Shock; Tendinopathy; Arthritis, Rheumatoid; Bone Diseases, Metabolic; Muscle Cramp; Myocardial Ischemia; Osteoporosis; Raynaud Disease; Reperfusion Injury; Scleroderma, Localized; Stroke; Wounds and Injuries; Angina Pectoris; Angina, Stable; Cardiovascular Diseases; Coronary Artery Disease; Coronary Disease; Heart Failure; Hemorrhoids; Hypertension; Myocardial Infarction; Pain
Soluble guanylate cyclase activator
Small molecule
Approved
CARDIOVASCULAR; OTHER; UROLOGY AND KIDNEY
INJECTION; URETHRAL
Arteriosclerosis Obliterans; Optic Neuropathy, Ischemic; Peripheral Arterial Disease; Peripheral Vascular Diseases; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Sexual Dysfunction, Physiological; Heart Failure; Macular Degeneration; Prostatic Neoplasms, Castration-Resistant; Cardiovascular Diseases; Ductus Arteriosus, Patent; Erectile Dysfunction
Prostanoid EP1 receptor agonist
Small molecule
Unknown
Unknown
Unknown
Amyotrophic Lateral Sclerosis; Depression; Depressive Disorder; Depressive Disorder, Major
Serotonin 2a (5-HT2a) receptor antagonist