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Total: 6532
Small molecule
Approved
Unknown
Unknown
Psychotic Disorders
Unknown
Small molecule
Approved
Unknown
Unknown
Atrial Fibrillation; Heart Failure; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Breast Neoplasms; Hypothyroidism; Bipolar Disorder; Depressive Disorder
Thyroid hormone receptor agonist
Small molecule
Approved
OTHER
ORAL
Breast Neoplasms; Hypogonadism; Neoplasms; Orchitis
Androgen Receptor agonist
Small molecule
Approved
Unknown
Unknown
Hypotension, Orthostatic; Lipoma; Orthostatic Intolerance; Atrial Fibrillation; Kidney Calculi; Cardiovascular Diseases; Lung Diseases, Obstructive
Unknown
Small molecule
Approved
Unknown
Unknown
Dementia; Depressive Disorder; Schizophrenia; Anxiety
Unknown
Small molecule
Approved
OTHER
ORAL
Melanoma; Venous Thrombosis; Thrombosis
Vitamin k epoxide reductase complex subunit 1 isoform 1 inhibitor
Small molecule
Approved
OTHER
ORAL
Carcinoma, Pancreatic Ductal; Lymphoma, Mantle-Cell; Glomerulonephritis, Membranous; Glomerulosclerosis, Focal Segmental; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Stomach Neoplasms; Hodgkin Disease; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma
DNA inhibitor
Small molecule
Approved
OTHER
ORAL
Friedreich Ataxia; Atherosclerosis; Chemical and Drug Induced Liver Injury; Cognitive Dysfunction; DiGeorge Syndrome; Frontotemporal Dementia; Gangliosidoses; Gaucher Disease; Hearing Loss, Noise-Induced; Immune System Diseases; Mucocutaneous Lymph Node Syndrome; Muscular Diseases; Myasthenia Gravis; Optic Nerve Diseases; Ovarian Hyperstimulation Syndrome; Parkinson Disease; Stiff-Person Syndrome; Adenomatous Polyposis Coli; Amyotrophic Lateral Sclerosis; Anemia, Aplastic; Appendicitis; Breast Neoplasms; Burkitt Lymphoma; Carcinoma, Non-Small-Cell Lung; Carpal Tunnel Syndrome; Coronavirus Infections; Death, Sudden, Cardiac; Fallopian Tube Neoplasms; Fanconi Anemia; Fasciitis, Plantar; Graves Ophthalmopathy; Hantavirus Infections; Hepatitis, Alcoholic; Hyperlipoproteinemia Type I; Immunoblastic Lymphadenopathy; Immunoglobulin G4-Related Disease; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, AIDS-Related; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Lymphoproliferative Disorders; Melanoma; Meniere Disease; Myelodysplastic-Myeloproliferative Diseases; Myelodysplastic Syndromes; Myeloproliferative Disorders; Nasal Polyps; Neoplasms; Neuromyelitis Optica; Ovarian Neoplasms; Pain; Prostatic Neoplasms; Purpura, Schoenlein-Henoch; Radiculopathy; Sinusitis; Spasms, Infantile; Spondylarthropathies; Spondylitis, Ankylosing; Abdominal Pain; Aging; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Bell Palsy; Bronchopulmonary Dysplasia; Deglutition Disorders; Dermatomyositis; Edema; Glomerulonephritis, IGA; Glomerulonephritis, Membranous; Graft vs Host Disease; Granulomatosis with Polyangiitis; Heart Arrest; Heart Diseases; Hematologic Neoplasms; Hematoma, Subdural, Intracranial; Hodgkin Disease; Ischemic Stroke; Kidney Diseases; Leukemia; Leukemia, Biphenotypic, Acute; Lupus Erythematosus, Systemic; Lupus Nephritis; Lymphohistiocytosis, Hemophagocytic; Lymphoma; Microscopic Polyangiitis; Multiple Myeloma; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Optic Neuritis; Optic Neuropathy, Ischemic; Pneumonia, Pneumocystis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Pulpitis; Purpura, Thrombocytopenic, Idiopathic; Renal Insufficiency, Chronic; Respiratory Distress Syndrome; Respiratory Tract Diseases; Scleroderma, Systemic; Severe Acute Respiratory Syndrome; Specific Language Disorder; Spinal Cord Injuries; Thrombocytopenia; Urinary Tract Infections; Vestibular Neuronitis; Acne Vulgaris; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Bursitis; Colitis, Ulcerative; Crohn Disease; Dermatitis, Atopic; Inflammation; Multiple Sclerosis; Osteoarthritis; Pneumonia; Tenosynovitis
Glucocorticoid receptor agonist
Small molecule
Approved
OTHER
ORAL
Unknown
Bacterial 70S ribosome inhibitor
Small molecule
Approved
OTHER
IM-IV; INJECTION; ORAL
Liver Cirrhosis; Pain
Carbonic anhydrase I inhibitor
Small molecule
Approved
OTHER
ORAL
Psoriasis; Sinusitis; Diabetic Retinopathy; Lichen Planus, Oral; Macular Degeneration; Nasal Polyps; Optic Neuropathy, Ischemic; Rotator Cuff Injuries; Abdominal Pain; Acneiform Eruptions; Alopecia Areata; Dermatitis, Atopic; Melanoma; Melanosis; Osteoarthritis, Knee; Shoulder Pain; Vascular Diseases; Vitiligo; Wet Macular Degeneration; Keloid; Macular Edema; Osteoarthritis; Pain; Pancreatitis, Chronic; Pulmonary Disease, Chronic Obstructive; Radiculopathy; Retinal Vein Occlusion; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Eye Diseases; Hemorrhoids; Lung Diseases, Obstructive; Nasal Obstruction; Skin Diseases
Glucocorticoid receptor agonist
Small molecule
Approved
Unknown
Unknown
Pain
Unknown
Small molecule
Approved
OTHER
INJECTION; ORAL
Common Cold; Cough; Hypersensitivity
Histamine H1 receptor antagonist
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Digestive System Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Hypersensitivity
Unknown
Small molecule
Approved
OTHER
OPHTHALMIC
Glaucoma
Acetylcholinesterase inhibitor
Small molecule
Approved
OTHER
RECTAL
Delirium; Glioblastoma; Neonatal Abstinence Syndrome; Severe Acute Respiratory Syndrome; Conduct Disorder; Porphyrias; Postoperative Nausea and Vomiting; Psychotic Disorders; Schizophrenia
D2-like dopamine receptor antagonist
Small molecule
Approved
OTHER
ORAL
Unknown
Vitamin K-dependent gamma-carboxylase inhibitor
Small molecule
Approved
Unknown
Unknown
Carcinoma, Hepatocellular; Smoking Cessation; Vertigo; Hypersensitivity
Unknown
Small molecule
Approved
OTHER
INJECTION; ORAL
Cocaine-Related Disorders; Anxiety; Dementia; Depressive Disorder; Psychomotor Agitation; Postoperative Nausea and Vomiting; Psychotic Disorders; Schizophrenia
Dopamine D2 receptor antagonist
Small molecule
Approved
OTHER
ORAL
Unknown
Muscarinic acetylcholine receptor M1 antagonist
Small molecule
Approved
OTHER
ORAL
Hypertension
Synaptic vesicular amine transporter inhibitor
Small molecule
Approved
OTHER
ORAL
Epilepsy; Seizures
Voltage-gated T-type calcium channel blocker
Small molecule
Approved
OTHER
ORAL
Epilepsy; Seizures
Sodium channel alpha subunit blocker
Small molecule
Approved
OTHER
ORAL
Psychotic Disorders
Dopamine D2 receptor antagonist
Small molecule
Approved
Unknown
Unknown
Low Back Pain
Unknown
Small molecule
Approved
OTHER
ORAL
Diabetes Mellitus; Diabetes Mellitus, Type 2
Sulfonylurea receptor 1, Kir6.2 blocker
Small molecule
Approved
EYE; OTHER
INTRAOCULAR; INTRAVITREAL; OPHTHALMIC; ORAL; TOPICAL
Hypertension; Radius Fractures; Tooth Diseases; Adrenal Insufficiency; Aortic Coarctation; Brain Edema; Esophageal Neoplasms; Graves Disease; Head and Neck Neoplasms; Heart Failure; Lacrimal Apparatus Diseases; Lung Neoplasms; Lymphoma, T-Cell, Cutaneous; Meningeal Carcinomatosis; Osteoarthritis, Knee; Rheumatic Diseases; Rotator Cuff Injuries; Scleritis; Vitiligo; Appendicitis; Blast Crisis; Brain Neoplasms; Breast Carcinoma In Situ; Breast Neoplasms; Burkitt Lymphoma; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Castleman Disease; Cholangiocarcinoma; Dry Eye Syndromes; Dyspnea; Endocrine Gland Neoplasms; Endometrial Neoplasms; Fasciitis, Plantar; Glomerulonephritis; Gout; Hearing Loss; Hearing Loss, Sensorineural; Hematologic Neoplasms; Hematoma, Subdural, Intracranial; Hemorrhage; Histiocytosis, Langerhans-Cell; Histiocytosis, Sinus; Intestinal Obstruction; Intracranial Hypertension; Kidney Diseases; Leptospirosis; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Plasma Cell; Leukemia, T-Cell; Lichen Planus; Liposarcoma, Myxoid; Liver Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Peripheral; Macular Degeneration; Melanoma; Meningitis; Meningitis, Cryptococcal; Mesothelioma; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neck Pain; Neoplasm Metastasis; Nervous System Diseases; Pancreatic Neoplasms; POEMS Syndrome; Premature Birth; Pulmonary Fibrosis; Purpura, Schoenlein-Henoch; Purpura, Thrombotic Thrombocytopenic; Radiculopathy; Rectal Neoplasms; Red-Cell Aplasia, Pure; Respiratory Tract Diseases; Retinal Vein Occlusion; Sciatica; Stomach Neoplasms; Tonsillitis; Toxoplasmosis, Cerebral; Tuberculosis; Urinary Bladder Neoplasms; Uveitis, Intermediate; Wet Macular Degeneration; Xerostomia; Amyloidosis; Amyloidosis, Familial; Anemia; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Anemia, Sickle Cell; Atrioventricular Block; Back Pain; Blepharitis; Bronchiolitis; Bronchopulmonary Dysplasia; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Cataract; Chronic Pain; Colorectal Neoplasms; Conjunctivitis, Viral; Cysticercosis; Deafness; Deglutition Disorders; Dermatitis; Encephalitis, Herpes Simplex; Fatigue; Genital Neoplasms, Female; Glaucoma; Glomerulosclerosis, Focal Segmental; Graft vs Host Disease; Granuloma, Lethal Midline; Headache; HELLP Syndrome; Hernias, Diaphragmatic, Congenital; Hodgkin Disease; Hypersensitivity; Knee Injuries; Leiomyoma; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Leukemia, Promyelocytic, Acute; Lichen Planus, Oral; Liver Cirrhosis; Lymphohistiocytosis, Hemophagocytic; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Malaria; Mastoiditis; Meniere Disease; Migraine Disorders; Multiple Myeloma; Myelodysplastic Syndromes; Nausea; Nephrosis; Neuralgia; Otitis Externa; Otitis Media; Ovarian Hyperstimulation Syndrome; Ovarian Neoplasms; Pain; Pelvic Organ Prolapse; Plasmacytoma; Pneumonia, Viral; Postoperative Nausea and Vomiting; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Renal Insufficiency, Chronic; Respiratory Distress Syndrome; Rhinitis, Allergic, Perennial; Sarcoma; Severe Acute Respiratory Syndrome; Small Cell Lung Carcinoma; Smoldering Multiple Myeloma; Specific Language Disorder; Strabismus; Urinary Tract Infections; Uveitis, Anterior; Vaginosis, Bacterial; Vitreoretinopathy, Proliferative; Vomiting; Waldenstrom Macroglobulinemia; Wounds and Injuries; Acne Vulgaris; Addison Disease; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Anemia, Aplastic; Anemia, Hemolytic; Arthritis, Gouty; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Bursitis; Chorioretinitis; Choroiditis; Colitis, Ulcerative; Conjunctivitis, Allergic; Crohn Disease; Dermatitis, Atopic; Dermatitis, Contact; Dermatitis, Exfoliative; Dermatitis Herpetiformis; Dermatitis, Seborrheic; Diabetic Retinopathy; Erythema Multiforme; Eye Diseases; Hemorrhoids; Herpes Zoster Ophthalmicus; Hypercalcemia; Infections; Inflammation; Iridocyclitis; Iritis; Keratitis; Leukemia; Lupus Erythematosus, Systemic; Lymphoma; Macular Edema; Multiple Sclerosis; Mycosis Fungoides; Myocarditis; Nasal Obstruction; Neoplasms; Nephrotic Syndrome; Ophthalmia, Sympathetic; Optic Neuritis; Osteoarthritis; Pemphigus; Peptic Ulcer; Pneumonia; Psoriasis; Pulmonary Eosinophilia; Purpura, Thrombocytopenic, Idiopathic; Rhinitis, Allergic, Seasonal; Sarcoidosis; Serum Sickness; Spondylitis, Ankylosing; Stevens-Johnson Syndrome; Synovitis; Tennis Elbow; Tenosynovitis; Thrombocytopenia; Thyroiditis, Subacute; Trichinellosis; Tuberculosis, Meningeal; Tuberculosis, Pulmonary; Uveitis, Posterior
Glucocorticoid receptor agonist
Small molecule
Approved
OTHER
ORAL
Unknown
Intermediate conductance calcium-activated potassium channel protein 4 opener
Small molecule
Approved
OTHER
ORAL
Unknown
DNA inhibitor
Small molecule
Approved
Unknown
Unknown
Unknown
Alpha-1a adrenergic receptor agonist
Small molecule
Approved
OTHER
ORAL
Cough
Slowly adapting pulmonary stretch receptor inhibitor
Small molecule
Approved
OTHER
ORAL
Unknown
Bacterial penicillin-binding protein inhibitor
Small molecule
Approved
OTHER
ORAL
Atherosclerosis; Coronary Disease; Diabetes Mellitus, Type 2; Heart Diseases; Hypercholesterolemia; Cardiovascular Diseases; Edema; Glomerulonephritis; Heart Failure; Hypertension; Kidney Failure, Chronic; Nephrotic Syndrome; Toxemia
Thiazide-sensitive sodium-chloride cotransporter inhibitor