DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 1496


Small molecule Approved OTHER TOPICAL Tinea Pedis Cytochrome P450 51 inhibitor


Small molecule Approved OTHER ORAL Arthritis, Rheumatoid; Cerebral Hemorrhage; Pre-Eclampsia; Proteinuria; Heart Failure; Hypertension; Ventricular Dysfunction, Left Angiotensin-converting enzyme inhibitor


Small molecule Approved OTHER ORAL Cognitive Dysfunction; Joint Diseases; Alcoholism; Anemia, Sickle Cell; Bipolar Disorder; Essential Tremor; Multiple Sclerosis; Schizophrenia; Substance-Related Disorders; Alcohol Drinking; Amyotrophic Lateral Sclerosis; Arthritis, Psoriatic; Chronic Pain; Dementia; HIV Infections; Irritable Bowel Syndrome; Marijuana Abuse; Migraine with Aura; Migraine without Aura; Opioid-Related Disorders; Pain; Sleep Apnea, Obstructive; Stress Disorders, Post-Traumatic; Torticollis; Tourette Syndrome; Trichotillomania; Anorexia Nervosa; Osteoarthritis, Knee; Anorexia; Nausea; Neoplasms; Postoperative Nausea and Vomiting Cannabinoid CB1 receptor agonist

Small molecule

Approved

OTHER

ORAL

Cognitive Dysfunction; Joint Diseases; Alcoholism; Anemia, Sickle Cell; Bipolar Disorder; Essential Tremor; Multiple Sclerosis; Schizophrenia; Substance-Related Disorders; Alcohol Drinking; Amyotrophic Lateral Sclerosis; Arthritis, Psoriatic; Chronic Pain; Dementia; HIV Infections; Irritable Bowel Syndrome; Marijuana Abuse; Migraine with Aura; Migraine without Aura; Opioid-Related Disorders; Pain; Sleep Apnea, Obstructive; Stress Disorders, Post-Traumatic; Torticollis; Tourette Syndrome; Trichotillomania; Anorexia Nervosa; Osteoarthritis, Knee; Anorexia; Nausea; Neoplasms; Postoperative Nausea and Vomiting

Cannabinoid CB1 receptor agonist


Small molecule Approved OTHER; PREGNANCY AND GYNECOLOGY VAGINAL Vulvovaginitis Cytochrome P450 51 inhibitor


Small molecule Approved OTHER OPHTHALMIC Rheumatic Diseases Cyclooxygenase inhibitor


Small molecule Approved OTHER ORAL Hepatolenticular Degeneration; Alcoholism; Feeding and Eating Disorders; Obesity; Bipolar Disorder; Lung Neoplasms; Smoking Cessation; Tobacco Use Disorder; Depressive Disorder; Depressive Disorder, Major; Mood Disorders; Seasonal Affective Disorder Dopamine transporter inhibitor


Small molecule Approved OTHER INJECTION Arrhythmias, Cardiac; Ventricular Fibrillation Norepinephrine transporter substrate


Small molecule Approved OTHER TOPICAL Lice Infestations; Lyme Disease; Ectoparasitic Infestations Voltage-sensitive sodium channel blocker


Small molecule Approved OTHER TOPICAL Unknown Unknown


Small molecule Approved MUSCULOSKELETAL; OTHER; RHEUMATOLOGY ORAL Kidney Calculi; Renal Colic; Paget Disease, Extramammary; Periodontitis; Bursitis; Inflammation; Low Back Pain; Migraine Disorders; Osteoarthritis, Knee; Postoperative Nausea and Vomiting; Sprains and Strains; Tendinopathy; Wounds and Injuries; Acute Pain; Arthralgia; Arthritis, Rheumatoid; Dysmenorrhea; Myalgia; Osteoarthritis; Pain; Rheumatic Diseases Cyclooxygenase inhibitor

Small molecule

Approved

MUSCULOSKELETAL; OTHER; RHEUMATOLOGY

ORAL

Kidney Calculi; Renal Colic; Paget Disease, Extramammary; Periodontitis; Bursitis; Inflammation; Low Back Pain; Migraine Disorders; Osteoarthritis, Knee; Postoperative Nausea and Vomiting; Sprains and Strains; Tendinopathy; Wounds and Injuries; Acute Pain; Arthralgia; Arthritis, Rheumatoid; Dysmenorrhea; Myalgia; Osteoarthritis; Pain; Rheumatic Diseases

Cyclooxygenase inhibitor


Protein Approved OTHER UNKNOWN Breast Carcinoma In Situ; Breast Neoplasms; Hematologic Neoplasms; Leukemia; Ovarian Neoplasms; Carcinoma, Renal Cell; Kidney Neoplasms; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liver Neoplasms; Neoplasms; Pancreatic Neoplasms; Papillomavirus Infections; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Severe Acute Respiratory Syndrome; Carcinoid Tumor; Carcinoma, Hepatocellular; Hepatitis C; HIV Infections; Liver Cirrhosis; Multiple Myeloma; Neoplasm Metastasis; Condylomata Acuminata; Hepatitis B, Chronic; Hepatitis C, Chronic; Leukemia, Hairy Cell; Lymphoma, Follicular; Melanoma; Sarcoma, Kaposi Interferon alpha/beta receptor agonist

Protein

Approved

OTHER

UNKNOWN

Breast Carcinoma In Situ; Breast Neoplasms; Hematologic Neoplasms; Leukemia; Ovarian Neoplasms; Carcinoma, Renal Cell; Kidney Neoplasms; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liver Neoplasms; Neoplasms; Pancreatic Neoplasms; Papillomavirus Infections; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Severe Acute Respiratory Syndrome; Carcinoid Tumor; Carcinoma, Hepatocellular; Hepatitis C; HIV Infections; Liver Cirrhosis; Multiple Myeloma; Neoplasm Metastasis; Condylomata Acuminata; Hepatitis B, Chronic; Hepatitis C, Chronic; Leukemia, Hairy Cell; Lymphoma, Follicular; Melanoma; Sarcoma, Kaposi

Interferon alpha/beta receptor agonist


Small molecule Approved OTHER ORAL Cryptosporidiosis; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Crohn Disease; Mycobacterium avium-intracellulare Infection; Tuberculosis; Leprosy DNA inhibitor


Small molecule Approved OTHER; RESPIRATORY INHALATION; INJECTION Osteomyelitis; Renal Insufficiency; Gonorrhea; Enterobacteriaceae Infections; Skin Diseases; Bacterial Infections; Cystic Fibrosis; Infections; Intraabdominal Infections; Pneumonia; Pyelonephritis; Sepsis; Urinary Tract Infections Bacterial penicillin-binding protein inhibitor


Small molecule Approved OTHER INJECTION Delirium; Conduct Disorder; Psychotic Disorders; Schizophrenia; Tourette Syndrome D2-like dopamine receptor inverse agonist


Small molecule Approved OTHER ORAL Anemia; Arthritis, Rheumatoid; Diabetes Mellitus, Type 2; HIV Infections; Mitochondrial Diseases; Low Back Pain; Periodontitis; Pain; Pharyngitis; Arthralgia; Eye Diseases; Miosis; Myalgia; Rheumatic Diseases Cyclooxygenase inhibitor


Small molecule Approved OTHER ORAL Psoriasis Retinoid receptor agonist


Small molecule Approved OTHER; PREGNANCY AND GYNECOLOGY INJECTION; INTRAVENOUS; ORAL Back Pain; Hypotension; Skin Neoplasms; Cerebral Hemorrhage; Epistaxis; Ileus; Intervertebral Disc Degeneration; Osteoarthritis, Knee; Shock, Septic; Subarachnoid Hemorrhage; Urinary Bladder Neoplasms; Anemia; Angioedemas, Hereditary; Aortic Aneurysm, Abdominal; Astrocytoma; Blood Coagulation Disorders; Bone Neoplasms; Brain Injuries; Brain Neoplasms; Coronary Disease; Femoral Neck Fractures; Fractures, Bone; Gastrointestinal Hemorrhage; Genital Neoplasms, Female; Glioma; Head and Neck Neoplasms; Hematologic Neoplasms; Hematoma; Hematoma, Subdural, Intracranial; Hemoptysis; Hip Fractures; Joint Diseases; Leiomyoma; Melanosis; Meningioma; Nasal Polyps; Neoplasms; Osteoarthritis; Pain; Pelvic Organ Prolapse; Placenta Accreta; Placenta Previa; Postpartum Hemorrhage; Scoliosis; Sepsis; Severe Acute Respiratory Syndrome; Shock; Shoulder Impingement Syndrome; Telangiectasia, Hereditary Hemorrhagic; Thrombocytopenia; Wounds and Injuries; Hemophilia A; Hemorrhage; Menorrhagia Plasminogen inhibitor

Small molecule

Approved

OTHER; PREGNANCY AND GYNECOLOGY

INJECTION; INTRAVENOUS; ORAL

Back Pain; Hypotension; Skin Neoplasms; Cerebral Hemorrhage; Epistaxis; Ileus; Intervertebral Disc Degeneration; Osteoarthritis, Knee; Shock, Septic; Subarachnoid Hemorrhage; Urinary Bladder Neoplasms; Anemia; Angioedemas, Hereditary; Aortic Aneurysm, Abdominal; Astrocytoma; Blood Coagulation Disorders; Bone Neoplasms; Brain Injuries; Brain Neoplasms; Coronary Disease; Femoral Neck Fractures; Fractures, Bone; Gastrointestinal Hemorrhage; Genital Neoplasms, Female; Glioma; Head and Neck Neoplasms; Hematologic Neoplasms; Hematoma; Hematoma, Subdural, Intracranial; Hemoptysis; Hip Fractures; Joint Diseases; Leiomyoma; Melanosis; Meningioma; Nasal Polyps; Neoplasms; Osteoarthritis; Pain; Pelvic Organ Prolapse; Placenta Accreta; Placenta Previa; Postpartum Hemorrhage; Scoliosis; Sepsis; Severe Acute Respiratory Syndrome; Shock; Shoulder Impingement Syndrome; Telangiectasia, Hereditary Hemorrhagic; Thrombocytopenia; Wounds and Injuries; Hemophilia A; Hemorrhage; Menorrhagia

Plasminogen inhibitor


Protein Approved OTHER INJECTION Parathyroid Diseases Calcitonin receptor agonist


Small molecule Approved OTHER OPHTHALMIC; ORAL Osteomyelitis; Hepatopulmonary Syndrome; Esophageal and Gastric Varices; Liver Cirrhosis; Peritonitis; Urinary Tract Infections; Bacterial Infections; Eye Infections Bacterial DNA gyrase inhibitor


Small molecule Approved OTHER IMPLANTATION; INHALATION; NASAL; TOPICAL Hypersensitivity; Spinal Cord Injuries; Anemia, Sickle Cell; Dermatitis, Atopic; Eosinophilic Esophagitis; Pemphigoid, Bullous; Psoriasis; Breast Neoplasms; Hypertrophy; Otitis Media with Effusion; Pulmonary Disease, Chronic Obstructive; Rhinitis, Allergic, Perennial; Severe Acute Respiratory Syndrome; Sinusitis; Sleep Apnea, Obstructive; Asthma; Lung Diseases, Obstructive; Nasal Obstruction; Nasal Polyps; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal; Skin Diseases Glucocorticoid receptor agonist

Small molecule

Approved

OTHER

IMPLANTATION; INHALATION; NASAL; TOPICAL

Hypersensitivity; Spinal Cord Injuries; Anemia, Sickle Cell; Dermatitis, Atopic; Eosinophilic Esophagitis; Pemphigoid, Bullous; Psoriasis; Breast Neoplasms; Hypertrophy; Otitis Media with Effusion; Pulmonary Disease, Chronic Obstructive; Rhinitis, Allergic, Perennial; Severe Acute Respiratory Syndrome; Sinusitis; Sleep Apnea, Obstructive; Asthma; Lung Diseases, Obstructive; Nasal Obstruction; Nasal Polyps; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal; Skin Diseases

Glucocorticoid receptor agonist


Small molecule Approved CARDIOVASCULAR; OTHER ORAL Inflammation; Asthma; Leukemia, Myeloid, Acute; Metabolic Diseases; Porokeratosis; Stroke; Arthritis, Rheumatoid; Breast Neoplasms; Carotid Stenosis; Cognitive Dysfunction; Fragile X Syndrome; Heart Diseases; HIV Infections; Intracranial Arteriosclerosis; Intracranial Arteriovenous Malformations; Learning Disabilities; Melanoma; Neurofibromatosis 1; Ovarian Neoplasms; Parkinson Disease; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Rett Syndrome; Xanthomatosis, Cerebrotendinous; Intermittent Claudication; Lipid Metabolism Disorders; Myocardial Ischemia; Atherosclerosis; Cardiovascular Diseases; Coronary Artery Disease; Coronary Disease; Hypercholesterolemia; Hypothyroidism HMG-CoA reductase inhibitor

Small molecule

Approved

CARDIOVASCULAR; OTHER

ORAL

Inflammation; Asthma; Leukemia, Myeloid, Acute; Metabolic Diseases; Porokeratosis; Stroke; Arthritis, Rheumatoid; Breast Neoplasms; Carotid Stenosis; Cognitive Dysfunction; Fragile X Syndrome; Heart Diseases; HIV Infections; Intracranial Arteriosclerosis; Intracranial Arteriovenous Malformations; Learning Disabilities; Melanoma; Neurofibromatosis 1; Ovarian Neoplasms; Parkinson Disease; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Rett Syndrome; Xanthomatosis, Cerebrotendinous; Intermittent Claudication; Lipid Metabolism Disorders; Myocardial Ischemia; Atherosclerosis; Cardiovascular Diseases; Coronary Artery Disease; Coronary Disease; Hypercholesterolemia; Hypothyroidism

HMG-CoA reductase inhibitor


Small molecule Approved OTHER VAGINAL Vaginitis; Candidiasis, Vulvovaginal Cytochrome P450 51 inhibitor


Small molecule Approved OTHER ORAL Unknown Norepinephrine transporter releasing agent


Small molecule Approved DERMATOLOGY; OTHER TOPICAL Osteomyelitis; Cystic Fibrosis; Hemangioma; Radiodermatitis; Epistaxis; Staphylococcal Infections; Telangiectasia, Hereditary Hemorrhagic; Impetigo; Infections; Nasal Obstruction Isoleucyl-tRNA synthetase inhibitor


Protein Approved OTHER INJECTION Unknown Insulin receptor agonist

Small molecule

Approved

GASTROINTESTINAL; OTHER; RESPIRATORY

INJECTION; ORAL; OTIC

Hepatitis, Alcoholic; Liver Cirrhosis, Alcoholic; Osteomyelitis; Rhinoscleroma; Carcinoma, Pancreatic Ductal; Diabetic Foot; Escherichia coli Infections; Hearing Loss; Hepatitis C; Leukemia, Myeloid, Acute; Lung Diseases; Lymphoma; Neoplasms; Periapical Periodontitis; Pseudomonas Infections; Purpura, Thrombocytopenic, Idiopathic; Amyotrophic Lateral Sclerosis; Anthrax; Cataract; Crohn Disease; Cystic Fibrosis; Leukemia, Lymphocytic, Chronic, B-Cell; Plague; Abscess; Breast Neoplasms; Bronchiectasis; Communicable Diseases; Diarrhea; Digestive System Diseases; Fever; Liver Abscess; Neutropenia; Otitis Media; Peritonitis; Pneumonia; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Sepsis; Urinary Bladder Neoplasms; Urolithiasis; Bacterial Infections; Bronchitis, Chronic; Cystitis; Eye Infections; Gonorrhea; Infections; Intraabdominal Infections; Otitis Externa; Prostatitis; Pyelonephritis; Sinusitis; Typhoid Fever; Urinary Tract Infections

Bacterial DNA gyrase inhibitor

Small molecule

Approved

GASTROINTESTINAL; OTHER

ORAL; RECTAL

Berylliosis; HIV Infections; Malnutrition; Adenoma; Colitis; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Diverticulum, Colon; Colitis, Collagenous; Colitis, Lymphocytic; Crohn Disease; Diverticular Diseases; Diverticulitis; Irritable Bowel Syndrome; Colitis, Ulcerative; Proctitis

Arachidonate 5-lipoxygenase inhibitor

Small molecule

Approved

OTHER

INJECTION; ORAL

Severe Combined Immunodeficiency; Castleman Disease; Infections; Leukemia-Lymphoma, Adult T-Cell; Liver Cirrhosis, Biliary; Lymphoma; Lymphoma, AIDS-Related; Paraparesis, Tropical Spastic; Sarcoma, Kaposi; Acquired Immunodeficiency Syndrome; AIDS Dementia Complex; AIDS-Related Complex; Diarrhea; Pneumonia, Pneumocystis; Pregnancy; Severe Acute Respiratory Syndrome; Tuberculosis; Autoimmune Diseases; HIV Infections; Virus Diseases

Human immunodeficiency virus type 1 reverse transcriptase inhibitor


Small molecule Approved OTHER; RESPIRATORY ORAL Osteomyelitis; Bronchitis, Chronic; Infections; Maxillary Sinusitis; Otitis Media; Pharyngitis; Pneumonia; Sinusitis; Tonsillitis; Urinary Tract Infections Bacterial penicillin-binding protein inhibitor


Small molecule Approved OTHER ORAL Unknown Cyclooxygenase-2 inhibitor

Small molecule

Approved

OTHER

ORAL

Glucose Intolerance; Huntington Disease; Liver Cirrhosis; Obesity; Adenomatous Polyposis Coli; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Cholangitis, Sclerosing; Cholestasis; Colorectal Neoplasms; Diabetes Mellitus, Type 2; Heart Failure; Inflammation; Jaundice, Obstructive; Non-alcoholic Fatty Liver Disease; Parkinson Disease; Pregnancy; Cholelithiasis; Cholestasis, Intrahepatic; Hepatitis C, Chronic; Liver Diseases; Liver Cirrhosis, Biliary

Bile acid receptor FXR agonist


Small molecule Approved OTHER ORAL Chemical and Drug Induced Liver Injury; Cystinuria; Subarachnoid Hemorrhage Reducing agent


Small molecule Approved OTHER TOPICAL Tinea; Tinea Pedis Cytochrome P450 51 inhibitor


Small molecule Approved OTHER INJECTION Unknown Unknown

Small molecule

Approved

OTHER

INJECTION

Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Neoplasm Metastasis; Breast Neoplasms; Burkitt Lymphoma; Leukemia, Myeloid, Acute; Lymphoma, AIDS-Related; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Nasopharyngeal Neoplasms; Pancreatic Neoplasms; Penile Neoplasms; Peritoneal Neoplasms; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Urethral Neoplasms; Urinary Bladder Neoplasms; Uterine Neoplasms; Wilms Tumor; Carcinoma; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Dermatofibrosarcoma; Endometrial Neoplasms; Fallopian Tube Neoplasms; Fibrosarcoma; Hemangiopericytoma; Hemangiosarcoma; Histiocytoma; Hodgkin Disease; Kidney Neoplasms; Leiomyosarcoma; Leukemia; Leukemia, Biphenotypic, Acute; Liposarcoma; Lung Neoplasms; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Mediastinal Neoplasms; Mesenchymoma; Neoplasms, Germ Cell and Embryonal; Neurilemmoma; Neuroblastoma; Osteosarcoma; Ovarian Neoplasms; Pheochromocytoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retroviridae Infections; Rhabdomyosarcoma; Sarcoma; Sarcoma, Alveolar Soft Part; Sarcoma, Ewing; Sarcoma, Synovial; Small Cell Lung Carcinoma; Teratoma; Uterine Cervical Neoplasms; Neoplasms; Testicular Neoplasms

DNA inhibitor