DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 1496


Small molecule Approved IMMUNE SYSTEM; OTHER DENTAL; TOPICAL Stomatitis; Lung Diseases, Obstructive Phosphodiesterase 4 inhibitor


Small molecule Approved OTHER ORAL Prostatic Neoplasms, Castration-Resistant; Neoplasms; Prostatic Neoplasms Androgen Receptor antagonist


Small molecule Approved IMMUNE SYSTEM; OTHER; PEDIATRICS ORAL Amyotrophic Lateral Sclerosis; Erectile Dysfunction; Glioblastoma; Hypertension; Hypertension, Pulmonary; Insulin Resistance; Kidney Diseases; Liver Diseases; Malaria; Neoplasm Metastasis; Respiratory Distress Syndrome; Tuberculosis; Coronavirus Infections; Hepatitis B, Chronic; Mycobacterium avium-intracellulare Infection; Neoplasms; Pregnancy; Sarcoma; Sarcoma, Kaposi; Acquired Immunodeficiency Syndrome; Hepatitis D; Infections; Severe Acute Respiratory Syndrome; Hepatitis C; Hepatitis C, Chronic; HIV Infections; Virus Diseases Cytochrome P450 3A inhibitor

Small molecule

Approved

IMMUNE SYSTEM; OTHER; PEDIATRICS

ORAL

Amyotrophic Lateral Sclerosis; Erectile Dysfunction; Glioblastoma; Hypertension; Hypertension, Pulmonary; Insulin Resistance; Kidney Diseases; Liver Diseases; Malaria; Neoplasm Metastasis; Respiratory Distress Syndrome; Tuberculosis; Coronavirus Infections; Hepatitis B, Chronic; Mycobacterium avium-intracellulare Infection; Neoplasms; Pregnancy; Sarcoma; Sarcoma, Kaposi; Acquired Immunodeficiency Syndrome; Hepatitis D; Infections; Severe Acute Respiratory Syndrome; Hepatitis C; Hepatitis C, Chronic; HIV Infections; Virus Diseases

Cytochrome P450 3A inhibitor


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Postoperative Nausea and Vomiting; Sleep Apnea, Obstructive; Alcoholism; Amphetamine-Related Disorders; Cocaine-Related Disorders; Fibromyalgia; Glioma; Substance-Related Disorders; Weight Loss; Anorexia; Anxiety; Cachexia; Child Development Disorders, Pervasive; Dementia; Heroin Dependence; Nausea; Schizophrenia; Depressive Disorder; Depressive Disorder, Major; Sleep Initiation and Maintenance Disorders Adrenergic receptor alpha-2 antagonist

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER

ORAL

Postoperative Nausea and Vomiting; Sleep Apnea, Obstructive; Alcoholism; Amphetamine-Related Disorders; Cocaine-Related Disorders; Fibromyalgia; Glioma; Substance-Related Disorders; Weight Loss; Anorexia; Anxiety; Cachexia; Child Development Disorders, Pervasive; Dementia; Heroin Dependence; Nausea; Schizophrenia; Depressive Disorder; Depressive Disorder, Major; Sleep Initiation and Maintenance Disorders

Adrenergic receptor alpha-2 antagonist


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Diabetes Mellitus, Type 1; Diabetes Mellitus; Diabetes Mellitus, Type 2 Lysosomal alpha-glucosidase inhibitor


Small molecule Approved EYE; IMMUNE SYSTEM; OTHER INJECTION Herpes Simplex; Kidney Diseases; Uterine Cervical Neoplasms; Anus Neoplasms; Infections; Papilloma; Sarcoma; Uterine Cervical Dysplasia; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Primary Immunodeficiency Diseases; Virus Diseases Human herpesvirus 1 DNA polymerase inhibitor


Small molecule Approved GASTROINTESTINAL; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER INJECTION; INTRAVENOUS Osteomyelitis; Gram-Negative Bacterial Infections; Pancreatitis; Respiratory Insufficiency; Communicable Diseases; Tuberculosis; Tuberculosis, Pulmonary; Enterobacteriaceae Infections; Neonatal Sepsis; Pneumonia; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Pyelonephritis; Sepsis; Shock, Septic; Bacteremia; Bacterial Infections; Infections; Intraabdominal Infections; Meningitis; Meningitis, Bacterial; Urinary Tract Infections Bacterial penicillin-binding protein inhibitor

Small molecule

Approved

GASTROINTESTINAL; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

INJECTION; INTRAVENOUS

Osteomyelitis; Gram-Negative Bacterial Infections; Pancreatitis; Respiratory Insufficiency; Communicable Diseases; Tuberculosis; Tuberculosis, Pulmonary; Enterobacteriaceae Infections; Neonatal Sepsis; Pneumonia; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Pyelonephritis; Sepsis; Shock, Septic; Bacteremia; Bacterial Infections; Infections; Intraabdominal Infections; Meningitis; Meningitis, Bacterial; Urinary Tract Infections

Bacterial penicillin-binding protein inhibitor


Small molecule Approved EYE; OTHER; UROLOGY AND KIDNEY INJECTION; OPHTHALMIC; ORAL Osteomyelitis; Endophthalmitis; Escherichia coli Infections; HIV Infections; Kidney Diseases; Urinary Bladder, Overactive; Appendicitis; Cellulitis; Diabetic Foot; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoidosis; Tuberculosis, Multidrug-Resistant; Cataract; Cystic Fibrosis; Dyspepsia; Endocarditis; Fever; Helicobacter Infections; Hot Flashes; Maxillary Sinusitis; Neutropenia; Otitis Media; Pelvic Inflammatory Disease; Pneumonia, Bacterial; Prostatic Hyperplasia; Prostatitis; Pulmonary Disease, Chronic Obstructive; Pyelonephritis; Skin Diseases; Staphylococcal Infections; Tuberculosis; Acne Vulgaris; Bacterial Infections; Bronchitis, Chronic; Conjunctivitis, Bacterial; Corneal Ulcer; Eye Infections; Infections; Otitis Externa; Pneumonia; Sinusitis; Urinary Tract Infections DNA gyrase inhibitor

Small molecule

Approved

EYE; OTHER; UROLOGY AND KIDNEY

INJECTION; OPHTHALMIC; ORAL

Osteomyelitis; Endophthalmitis; Escherichia coli Infections; HIV Infections; Kidney Diseases; Urinary Bladder, Overactive; Appendicitis; Cellulitis; Diabetic Foot; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoidosis; Tuberculosis, Multidrug-Resistant; Cataract; Cystic Fibrosis; Dyspepsia; Endocarditis; Fever; Helicobacter Infections; Hot Flashes; Maxillary Sinusitis; Neutropenia; Otitis Media; Pelvic Inflammatory Disease; Pneumonia, Bacterial; Prostatic Hyperplasia; Prostatitis; Pulmonary Disease, Chronic Obstructive; Pyelonephritis; Skin Diseases; Staphylococcal Infections; Tuberculosis; Acne Vulgaris; Bacterial Infections; Bronchitis, Chronic; Conjunctivitis, Bacterial; Corneal Ulcer; Eye Infections; Infections; Otitis Externa; Pneumonia; Sinusitis; Urinary Tract Infections

DNA gyrase inhibitor


Small molecule Approved OTHER OPHTHALMIC Meniere Disease; Vitiligo; Glaucoma; Glaucoma, Open-Angle; Hypertension; Ocular Hypertension Prostanoid FP receptor agonist


Unknown Approved DERMATOLOGY; IMMUNE SYSTEM; OTHER; PEDIATRICS ORAL; TOPICAL Alcoholism; Infections; Acne Vulgaris; Dengue; Dermatitis, Atopic; Severe Dengue; Trichuriasis; Blepharitis; Elephantiasis, Filarial; Malaria; Severe Acute Respiratory Syndrome; Helminthiasis; Lice Infestations; Onchocerciasis; Rosacea; Strongyloidiasis Glutamate-gated chloride channel modulator


Unknown Approved OTHER INJECTION Acute Kidney Injury Diagnostic agent


Protein Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER UNKNOWN Stroke; Alzheimer Disease; Asthma; Colitis, Ulcerative; Crohn Disease; Multiple Organ Failure; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Pulmonary Disease, Chronic Obstructive; Hepatitis C; Multiple Sclerosis, Relapsing-Remitting; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Multiple Sclerosis Interferon alpha/beta receptor agonist

Protein

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

UNKNOWN

Stroke; Alzheimer Disease; Asthma; Colitis, Ulcerative; Crohn Disease; Multiple Organ Failure; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Pulmonary Disease, Chronic Obstructive; Hepatitis C; Multiple Sclerosis, Relapsing-Remitting; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Multiple Sclerosis

Interferon alpha/beta receptor agonist


Small molecule Approved DERMATOLOGY; OTHER TOPICAL Skin Diseases; Acne Vulgaris Retinoic acid receptor agonist


Antibody Approved OTHER INTRAVENOUS Unknown Diagnostic agent


Antibody Approved OTHER UNKNOWN Unknown Unknown


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS ORAL Feeding and Eating Disorders; Bulimia Nervosa; Cognitive Dysfunction; Hernias, Diaphragmatic, Congenital; Liver Diseases; Alcohol Drinking; Amphetamine-Related Disorders; Brain Ischemia; Diabetes Mellitus; Marijuana Abuse; Multiple Sclerosis; Parkinson Disease; Sciatica; Stress Disorders, Post-Traumatic; Alcoholism; Anxiety; Bipolar Disorder; Bulimia; Cocaine-Related Disorders; Dementia; Depressive Disorder; Diabetes Mellitus, Type 2; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Essential Tremor; Gambling; Headache; Hyperlipidemias; Hypertension; Hypertriglyceridemia; Metabolic Syndrome; Obesity; Obsessive-Compulsive Disorder; Pain; Prader-Willi Syndrome; Schizophrenia; Smoking Cessation; Tobacco Use Disorder; Tourette Syndrome; Epilepsy; Lennox Gastaut Syndrome; Migraine Disorders; Seizures Carbonic anhydrase II inhibitor

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS

ORAL

Feeding and Eating Disorders; Bulimia Nervosa; Cognitive Dysfunction; Hernias, Diaphragmatic, Congenital; Liver Diseases; Alcohol Drinking; Amphetamine-Related Disorders; Brain Ischemia; Diabetes Mellitus; Marijuana Abuse; Multiple Sclerosis; Parkinson Disease; Sciatica; Stress Disorders, Post-Traumatic; Alcoholism; Anxiety; Bipolar Disorder; Bulimia; Cocaine-Related Disorders; Dementia; Depressive Disorder; Diabetes Mellitus, Type 2; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Essential Tremor; Gambling; Headache; Hyperlipidemias; Hypertension; Hypertriglyceridemia; Metabolic Syndrome; Obesity; Obsessive-Compulsive Disorder; Pain; Prader-Willi Syndrome; Schizophrenia; Smoking Cessation; Tobacco Use Disorder; Tourette Syndrome; Epilepsy; Lennox Gastaut Syndrome; Migraine Disorders; Seizures

Carbonic anhydrase II inhibitor


Enzyme Approved OTHER SINGLE-USE; UNKNOWN Retinal Vein Occlusion; Thrombophlebitis; Abdominal Abscess; Bronchitis; Neoplasms; Nervous System Diseases; Severe Acute Respiratory Syndrome; Urinary Retention; Venous Thrombosis; Abscess; Angina, Stable; Brain Ischemia; Cerebral Hemorrhage; Cerebral Infarction; Empyema; Empyema, Pleural; Hemorrhage; Ischemic Stroke; Myocardial Ischemia; Respiratory Distress Syndrome; Retinal Artery Occlusion; Subarachnoid Hemorrhage; Eye Diseases; Heart Failure; Myocardial Infarction; Pulmonary Embolism; Stroke; Thrombosis Plasminogen activator

Enzyme

Approved

OTHER

SINGLE-USE; UNKNOWN

Retinal Vein Occlusion; Thrombophlebitis; Abdominal Abscess; Bronchitis; Neoplasms; Nervous System Diseases; Severe Acute Respiratory Syndrome; Urinary Retention; Venous Thrombosis; Abscess; Angina, Stable; Brain Ischemia; Cerebral Hemorrhage; Cerebral Infarction; Empyema; Empyema, Pleural; Hemorrhage; Ischemic Stroke; Myocardial Ischemia; Respiratory Distress Syndrome; Retinal Artery Occlusion; Subarachnoid Hemorrhage; Eye Diseases; Heart Failure; Myocardial Infarction; Pulmonary Embolism; Stroke; Thrombosis

Plasminogen activator


Small molecule Approved OTHER; RESPIRATORY ORAL Breast Neoplasms; Ovarian Neoplasms; Asthma; Lung Diseases, Obstructive Cysteinyl leukotriene receptor 1 antagonist


Small molecule Approved OTHER ORAL HIV Infections; Alzheimer Disease; Dermatitis; Melanoma; Psoriasis Retinoid receptor agonist


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Breast Neoplasms; Obesity; Substance-Related Disorders; Cocaine-Related Disorders; Endometriosis; Infertility; Paget Disease, Extramammary; Pituitary ACTH Hypersecretion; Acromegaly; Diabetes Mellitus; Ovarian Hyperstimulation Syndrome; Restless Legs Syndrome; Parkinson Disease; Pituitary Neoplasms Dopamine D2 receptor agonist

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER

ORAL

Breast Neoplasms; Obesity; Substance-Related Disorders; Cocaine-Related Disorders; Endometriosis; Infertility; Paget Disease, Extramammary; Pituitary ACTH Hypersecretion; Acromegaly; Diabetes Mellitus; Ovarian Hyperstimulation Syndrome; Restless Legs Syndrome; Parkinson Disease; Pituitary Neoplasms

Dopamine D2 receptor agonist


Small molecule Approved CANCER; OTHER; PREGNANCY AND GYNECOLOGY INJECTION; INTRAVENOUS Breast Neoplasms, Male; Carcinoma, Endometrioid; Carcinoma, Renal Cell; Colonic Neoplasms; Cystadenoma, Serous; Digestive System Diseases; Lymphoma; Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Nausea; Sarcoma, Synovial; Vaginal Neoplasms; Vulvar Neoplasms; Adenocarcinoma; Anus Neoplasms; Biliary Tract Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Neuroendocrine; Carcinoma, Transitional Cell; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Hereditary Breast and Ovarian Cancer Syndrome; Leiomyosarcoma; Leukemia; Liver Neoplasms; Mediastinal Neoplasms; Melanoma; Osteosarcoma; Pancreatic Neoplasms; Penile Neoplasms; Retroviridae Infections; Small Cell Lung Carcinoma; Squamous Cell Carcinoma of Head and Neck; Testicular Neoplasms; Thyroid Carcinoma, Anaplastic; Tonsillar Neoplasms; Triple Negative Breast Neoplasms; Uterine Neoplasms; Adenocarcinoma of Lung; Anorexia; Cachexia; Carcinoma; Carcinoma, Squamous Cell; Endometrial Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Fatigue; Genital Neoplasms, Male; Head and Neck Neoplasms; Hypersensitivity; Hypopharyngeal Neoplasms; Inflammatory Breast Neoplasms; Kidney Neoplasms; Laryngeal Neoplasms; Lung Neoplasms; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neutropenia; Oropharyngeal Neoplasms; Ovarian Neoplasms; Paranasal Sinus Neoplasms; Peritoneal Neoplasms; Pharyngeal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Stomach Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasms Tubulin inhibitor

Small molecule

Approved

CANCER; OTHER; PREGNANCY AND GYNECOLOGY

INJECTION; INTRAVENOUS

Breast Neoplasms, Male; Carcinoma, Endometrioid; Carcinoma, Renal Cell; Colonic Neoplasms; Cystadenoma, Serous; Digestive System Diseases; Lymphoma; Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Nausea; Sarcoma, Synovial; Vaginal Neoplasms; Vulvar Neoplasms; Adenocarcinoma; Anus Neoplasms; Biliary Tract Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Neuroendocrine; Carcinoma, Transitional Cell; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Hereditary Breast and Ovarian Cancer Syndrome; Leiomyosarcoma; Leukemia; Liver Neoplasms; Mediastinal Neoplasms; Melanoma; Osteosarcoma; Pancreatic Neoplasms; Penile Neoplasms; Retroviridae Infections; Small Cell Lung Carcinoma; Squamous Cell Carcinoma of Head and Neck; Testicular Neoplasms; Thyroid Carcinoma, Anaplastic; Tonsillar Neoplasms; Triple Negative Breast Neoplasms; Uterine Neoplasms; Adenocarcinoma of Lung; Anorexia; Cachexia; Carcinoma; Carcinoma, Squamous Cell; Endometrial Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Fatigue; Genital Neoplasms, Male; Head and Neck Neoplasms; Hypersensitivity; Hypopharyngeal Neoplasms; Inflammatory Breast Neoplasms; Kidney Neoplasms; Laryngeal Neoplasms; Lung Neoplasms; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neutropenia; Oropharyngeal Neoplasms; Ovarian Neoplasms; Paranasal Sinus Neoplasms; Peritoneal Neoplasms; Pharyngeal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Stomach Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasms

Tubulin inhibitor


Unknown Approved OTHER INJECTION Unknown Unknown


Small molecule Approved OTHER INJECTION Diffuse Intrinsic Pontine Glioma; Bile Duct Neoplasms; Brain Neoplasms; Leukemia; Lymphoma, T-Cell, Cutaneous; Sarcoma, Synovial; Stomach Neoplasms; Adenocarcinoma; Adenocarcinoma of Lung; Anxiety; Biliary Tract Diseases; Carcinoma, Large Cell; Carcinoma, Renal Cell; Colonic Neoplasms; Colorectal Neoplasms; Digestive System Diseases; Endometrial Neoplasms; Esophageal Neoplasms; Gastrointestinal Stromal Tumors; Head and Neck Neoplasms; Hodgkin Disease; Kidney Neoplasms; Leiomyosarcoma; Leukemia-Lymphoma, Adult T-Cell; Liver Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, T-Cell; Medulloblastoma; Melanoma; Multiple Myeloma; Neoplasms, Germ Cell and Embryonal; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Small Cell Lung Carcinoma; Testicular Neoplasms; Thyroid Neoplasms; Urethral Neoplasms; Biliary Tract Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cholangiocarcinoma; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Granuloma, Lethal Midline; Hepatoblastoma; Immunoblastic Lymphadenopathy; Lung Neoplasms; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Mesothelioma; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Sarcoma; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Neoplasms Unknown

Small molecule

Approved

OTHER

INJECTION

Diffuse Intrinsic Pontine Glioma; Bile Duct Neoplasms; Brain Neoplasms; Leukemia; Lymphoma, T-Cell, Cutaneous; Sarcoma, Synovial; Stomach Neoplasms; Adenocarcinoma; Adenocarcinoma of Lung; Anxiety; Biliary Tract Diseases; Carcinoma, Large Cell; Carcinoma, Renal Cell; Colonic Neoplasms; Colorectal Neoplasms; Digestive System Diseases; Endometrial Neoplasms; Esophageal Neoplasms; Gastrointestinal Stromal Tumors; Head and Neck Neoplasms; Hodgkin Disease; Kidney Neoplasms; Leiomyosarcoma; Leukemia-Lymphoma, Adult T-Cell; Liver Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, T-Cell; Medulloblastoma; Melanoma; Multiple Myeloma; Neoplasms, Germ Cell and Embryonal; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Small Cell Lung Carcinoma; Testicular Neoplasms; Thyroid Neoplasms; Urethral Neoplasms; Biliary Tract Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cholangiocarcinoma; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Granuloma, Lethal Midline; Hepatoblastoma; Immunoblastic Lymphadenopathy; Lung Neoplasms; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Mesothelioma; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Sarcoma; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Neoplasms

Unknown


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Cardiovascular Diseases; Heart Failure; Hypertension; Myocardial Infarction; Ventricular Dysfunction, Left Angiotensin-converting enzyme inhibitor


Small molecule Approved OTHER; RESPIRATORY ORAL Inflammation; Anemia, Sickle Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Acne Vulgaris; Idiopathic Pulmonary Fibrosis; Lung Neoplasms; Tobacco Use Disorder; Pulmonary Disease, Chronic Obstructive; Asthma Arachidonate 5-lipoxygenase inhibitor


Small molecule Approved IMMUNE SYSTEM; OTHER; PHARMACOLOGY ORAL Unknown Bacterial DNA gyrase inhibitor

Antibody

Approved

HEMATOLOGY; OTHER

UNKNOWN

Neuroblastoma; Prostatic Neoplasms, Castration-Resistant; Arthritis, Psoriatic; Autoimmune Diseases; Candidiasis, Chronic Mucocutaneous; Carcinoma, Squamous Cell; Crohn Disease; Encephalomyelitis; Fanconi Anemia; Frontotemporal Dementia; Gangliosidoses; Glycogen Storage Disease Type II; Hematologic Diseases; Hematologic Neoplasms; Liver Cirrhosis, Biliary; Lymphoma, B-Cell; Lymphoma, T-Cell; Macular Degeneration; Muscular Diseases; Mycosis Fungoides; Opsoclonus-Myoclonus Syndrome; Parkinson Disease; Pemphigoid, Benign Mucous Membrane; Schizophrenia; Scleritis; Urticaria; Acquired Immunodeficiency Syndrome; Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; Anemia, Sickle Cell; Antiphospholipid Syndrome; Behcet Syndrome; Blast Crisis; Breast Neoplasms; Castleman Disease; Churg-Strauss Syndrome; Colitis, Ulcerative; Colonic Neoplasms; Dermatomyositis; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Encephalitis, Japanese; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Graves Ophthalmopathy; Heart Failure; Hemolytic-Uremic Syndrome; Hemophilia A; Histiocytosis, Langerhans-Cell; Idiopathic Pulmonary Fibrosis; Immunoblastic Lymphadenopathy; Leukemia, Biphenotypic, Acute; Leukemia, Hairy Cell; Leukemia, Mast-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Leukemia, Prolymphocytic; Lung Neoplasms; Lymphoma, AIDS-Related; Lymphoma, Large-Cell, Anaplastic; Lymphoproliferative Disorders; Melanoma; Multiple Myeloma; Multiple Sclerosis, Chronic Progressive; Multiple System Atrophy; Myelodysplastic Syndromes; Neuromyelitis Optica; Pancreatic Neoplasms; Peripheral Nervous System Diseases; Pneumococcal Infections; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Pulmonary Alveolar Proteinosis; Renal Insufficiency; Renal Insufficiency, Chronic; Sarcoidosis; Scleroderma, Systemic; Sjogren's Syndrome; Spondylitis, Ankylosing; Stiff-Person Syndrome; Stomach Neoplasms; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Burkitt Lymphoma; Fatigue Syndrome, Chronic; Glomerulonephritis, Membranous; Graft vs Host Disease; Hodgkin Disease; Immune System Diseases; Kidney Diseases; Leukemia; Leukemia, Lymphoid; Lung Diseases, Interstitial; Lupus Erythematosus, Systemic; Lupus Nephritis; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Myasthenia Gravis; Nephrotic Syndrome; Pemphigoid, Bullous; Pemphigus; Polyneuropathies; Proteinuria; Purpura, Thrombocytopenic, Idiopathic; Purpura, Thrombotic Thrombocytopenic; Waldenstrom Macroglobulinemia; Arthritis, Rheumatoid; Granulomatosis with Polyangiitis; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Microscopic Polyangiitis; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Systemic Vasculitis

B-lymphocyte antigen CD20 binding agent


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Gastrointestinal Stromal Tumors; Mitochondrial Diseases; Parkinson Disease; Prostatic Neoplasms, Castration-Resistant; Atherosclerosis; Coronary Disease; Cystic Fibrosis; Hypercholesterolemia; Hypertension; Diabetes Mellitus; Diabetes Mellitus, Type 2 Sulfonylurea receptor 1, Kir6.2 blocker

Protein

Approved

OTHER

INJECTION

Subarachnoid Hemorrhage; Adrenoleukodystrophy; alpha 1-Antitrypsin Deficiency; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Cerebral Hemorrhage; Cerebral Infarction; Craniocerebral Trauma; Graft vs Host Disease; Inflammation; Kidney Diseases; Macular Degeneration; Multiple Sclerosis, Relapsing-Remitting; Pneumonia; Scleroderma, Systemic; Shock; Abortion, Habitual; Ascites; Edema; Hypotension, Orthostatic; Ischemic Stroke; Liver Cirrhosis; Pancreatic Neoplasms; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Pulmonary Disease, Chronic Obstructive; Sepsis; Shock, Septic; Nephrosis; Respiratory Distress Syndrome

Bilirubin sequestering agent


Small molecule Approved OTHER INJECTION Unknown Bacterial DNA gyrase inhibitor

Small molecule

Approved

OTHER; PREGNANCY AND GYNECOLOGY

ORAL

Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Leiomyoma; Lymphoma, Non-Hodgkin; Mesothelioma; Adenomyosis; Adrenal Hyperplasia, Congenital; Anovulation; Carcinoma; Carcinoma, Lobular; Dwarfism; Endometriosis; Fallopian Tube Neoplasms; Hepatopulmonary Syndrome; Inflammatory Breast Neoplasms; Leiomyosarcoma; Lymphangioleiomyomatosis; Ovarian Neoplasms; Peritoneal Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Azoospermia; Carcinoma, Intraductal, Noninfiltrating; Endometrial Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Hypogonadism; Infertility; Menopause; Neoplasm Metastasis; Osteoporosis; Ovarian Hyperstimulation Syndrome; Polycystic Ovary Syndrome; Pregnancy; Breast Neoplasms; Neoplasms

Cytochrome P450 19A1 inhibitor


Small molecule Approved OTHER ORAL Sarcoma; Diabetes Mellitus Peroxisome proliferator-activated receptor gamma agonist


Small molecule Approved ENT; OTHER; PHARMACOLOGY; RESPIRATORY ORAL Appendicitis; Osteomyelitis; Mastitis; Bacterial Infections; Bronchitis, Chronic; Infections; Otitis Media; Pharyngitis; Pneumonia; Tonsillitis Bacterial penicillin-binding protein inhibitor

Small molecule

Approved

DERMATOLOGY; IMMUNE SYSTEM; OTHER

TOPICAL

Lymphoma, T-Cell, Cutaneous; Mouth Neoplasms; Astrocytoma; Brain Neoplasms; Carcinoma, Squamous Cell; Colorectal Neoplasms; Diffuse Intrinsic Pontine Glioma; Ependymoma; Glioblastoma; Glioma; Influenza in Birds; Medulloblastoma; Neoplasms; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Breast Neoplasms; Carcinoma in Situ; Carcinoma, Non-Small-Cell Lung; Cheilitis; Fallopian Tube Neoplasms; Hemangioma; Hepatitis B, Chronic; Keloid; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Melanoma; Ovarian Neoplasms; Papillomavirus Infections; Port-Wine Stain; Renal Insufficiency; Uterine Cervical Neoplasms; Anus Neoplasms; Cervical Intraepithelial Neoplasia; Condylomata Acuminata; Influenza, Human; Leishmaniasis, Cutaneous; Lentigo; Paget Disease, Extramammary; Scleroderma, Localized; Squamous Intraepithelial Lesions; Vulvar Neoplasms; Carcinoma, Basal Cell; Keratosis; Keratosis, Actinic; Virus Diseases

Toll-like receptor 7 agonist

Small molecule

Approved

OTHER

TOPICAL

Adrenal Hyperplasia, Congenital; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Bursitis; Colitis, Ulcerative; Conjunctivitis, Allergic; Dermatitis; Dermatitis, Atopic; Dermatitis, Seborrheic; Endocrine System Diseases; Exanthema; Inflammation; Leukemia; Lymphoma; Neoplasms; Osteoarthritis; Pruritus; Psoriasis; Serum Sickness; Skin Diseases; Spondylitis; Tenosynovitis

Glucocorticoid receptor agonist