DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 1496


Small molecule Approved IMMUNE SYSTEM; OTHER DENTAL; TOPICAL Stomatitis; Lung Diseases, Obstructive Phosphodiesterase 4 inhibitor


Small molecule Approved OTHER ORAL Prostatic Neoplasms, Castration-Resistant; Neoplasms; Prostatic Neoplasms Androgen Receptor antagonist


Small molecule Approved IMMUNE SYSTEM; OTHER; PEDIATRICS ORAL Amyotrophic Lateral Sclerosis; Anus Neoplasms; Erectile Dysfunction; Glioblastoma; Glioma; Hypertension; Hypertension, Pulmonary; Insulin Resistance; Kidney Diseases; Liver Diseases; Malaria; Neoplasm Metastasis; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Respiratory Distress Syndrome; Tuberculosis; Hepatitis B, Chronic; Mycobacterium avium-intracellulare Infection; Neoplasms; Post-Acute COVID-19 Syndrome; Pregnancy; Sarcoma; Sarcoma, Kaposi; Acquired Immunodeficiency Syndrome; Coronavirus Infections; Hepatitis D; Infections; Influenza, Human; Pneumonia; Severe Acute Respiratory Syndrome; Hepatitis C; Hepatitis C, Chronic; HIV Infections; Virus Diseases Cytochrome P450 3A inhibitor

Small molecule

Approved

IMMUNE SYSTEM; OTHER; PEDIATRICS

ORAL

Amyotrophic Lateral Sclerosis; Anus Neoplasms; Erectile Dysfunction; Glioblastoma; Glioma; Hypertension; Hypertension, Pulmonary; Insulin Resistance; Kidney Diseases; Liver Diseases; Malaria; Neoplasm Metastasis; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Respiratory Distress Syndrome; Tuberculosis; Hepatitis B, Chronic; Mycobacterium avium-intracellulare Infection; Neoplasms; Post-Acute COVID-19 Syndrome; Pregnancy; Sarcoma; Sarcoma, Kaposi; Acquired Immunodeficiency Syndrome; Coronavirus Infections; Hepatitis D; Infections; Influenza, Human; Pneumonia; Severe Acute Respiratory Syndrome; Hepatitis C; Hepatitis C, Chronic; HIV Infections; Virus Diseases

Cytochrome P450 3A inhibitor


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Postoperative Nausea and Vomiting; Sleep Apnea, Obstructive; Stomach Diseases; Alcoholism; Amphetamine-Related Disorders; Anorexia; Anorexia Nervosa; Cachexia; Cocaine-Related Disorders; Fibromyalgia; Paraganglioma; Substance-Related Disorders; Weight Loss; Anxiety; Child Development Disorders, Pervasive; Dementia; Heroin Dependence; Nausea; Schizophrenia; Depressive Disorder; Depressive Disorder, Major; Sleep Initiation and Maintenance Disorders Adrenergic receptor alpha-2 antagonist

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER

ORAL

Postoperative Nausea and Vomiting; Sleep Apnea, Obstructive; Stomach Diseases; Alcoholism; Amphetamine-Related Disorders; Anorexia; Anorexia Nervosa; Cachexia; Cocaine-Related Disorders; Fibromyalgia; Paraganglioma; Substance-Related Disorders; Weight Loss; Anxiety; Child Development Disorders, Pervasive; Dementia; Heroin Dependence; Nausea; Schizophrenia; Depressive Disorder; Depressive Disorder, Major; Sleep Initiation and Maintenance Disorders

Adrenergic receptor alpha-2 antagonist


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Diabetes Mellitus, Type 1; Diabetes Mellitus; Diabetes Mellitus, Type 2 Lysosomal alpha-glucosidase inhibitor


Small molecule Approved EYE; IMMUNE SYSTEM; OTHER INJECTION Condylomata Acuminata; Herpes Simplex; HIV Infections; Kidney Diseases; Uterine Cervical Neoplasms; Infections; Papilloma; Sarcoma; Uterine Cervical Dysplasia; Anus Neoplasms; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Primary Immunodeficiency Diseases; Virus Diseases Human herpesvirus 1 DNA polymerase inhibitor


Small molecule Approved GASTROINTESTINAL; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER INJECTION; INTRAVENOUS Gram-Negative Bacterial Infections; Osteomyelitis; Pancreatitis; Respiratory Insufficiency; Appendicitis; Communicable Diseases; Hematologic Neoplasms; Tuberculosis; Tuberculosis, Pulmonary; Enterobacteriaceae Infections; Lung Diseases; Mental Disorders; Neonatal Sepsis; Pneumonia; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Pyelonephritis; Sepsis; Shock, Septic; Urinary Bladder Neoplasms; Bacteremia; Bacterial Infections; Infections; Intraabdominal Infections; Meningitis; Meningitis, Bacterial; Urinary Tract Infections Bacterial penicillin-binding protein inhibitor

Small molecule

Approved

GASTROINTESTINAL; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

INJECTION; INTRAVENOUS

Gram-Negative Bacterial Infections; Osteomyelitis; Pancreatitis; Respiratory Insufficiency; Appendicitis; Communicable Diseases; Hematologic Neoplasms; Tuberculosis; Tuberculosis, Pulmonary; Enterobacteriaceae Infections; Lung Diseases; Mental Disorders; Neonatal Sepsis; Pneumonia; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Pyelonephritis; Sepsis; Shock, Septic; Urinary Bladder Neoplasms; Bacteremia; Bacterial Infections; Infections; Intraabdominal Infections; Meningitis; Meningitis, Bacterial; Urinary Tract Infections

Bacterial penicillin-binding protein inhibitor


Small molecule Approved EYE; OTHER; UROLOGY AND KIDNEY INJECTION; OPHTHALMIC; ORAL Endophthalmitis; Escherichia coli Infections; HIV Infections; Kidney Diseases; Appendicitis; Cellulitis; Diabetic Foot; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoidosis; Tuberculosis, Multidrug-Resistant; Bronchitis; Cataract; Dyspepsia; Endocarditis; Fever; Helicobacter Infections; Hot Flashes; Influenza, Human; Maxillary Sinusitis; Neutropenia; Otitis Media; Pelvic Inflammatory Disease; Pneumonia, Bacterial; Prostatic Hyperplasia; Prostatitis; Pulmonary Disease, Chronic Obstructive; Pyelonephritis; Severe Acute Respiratory Syndrome; Skin Diseases; Staphylococcal Infections; Tuberculosis; Tuberculosis, Pulmonary; Bacterial Infections; Bronchitis, Chronic; Conjunctivitis, Bacterial; Cystic Fibrosis; Eye Infections; Infections; Pneumonia; Respiratory Tract Infections; Sinusitis; Urinary Tract Infections DNA gyrase inhibitor

Small molecule

Approved

EYE; OTHER; UROLOGY AND KIDNEY

INJECTION; OPHTHALMIC; ORAL

Endophthalmitis; Escherichia coli Infections; HIV Infections; Kidney Diseases; Appendicitis; Cellulitis; Diabetic Foot; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoidosis; Tuberculosis, Multidrug-Resistant; Bronchitis; Cataract; Dyspepsia; Endocarditis; Fever; Helicobacter Infections; Hot Flashes; Influenza, Human; Maxillary Sinusitis; Neutropenia; Otitis Media; Pelvic Inflammatory Disease; Pneumonia, Bacterial; Prostatic Hyperplasia; Prostatitis; Pulmonary Disease, Chronic Obstructive; Pyelonephritis; Severe Acute Respiratory Syndrome; Skin Diseases; Staphylococcal Infections; Tuberculosis; Tuberculosis, Pulmonary; Bacterial Infections; Bronchitis, Chronic; Conjunctivitis, Bacterial; Cystic Fibrosis; Eye Infections; Infections; Pneumonia; Respiratory Tract Infections; Sinusitis; Urinary Tract Infections

DNA gyrase inhibitor


Small molecule Approved OTHER OPHTHALMIC Alopecia Areata; Meniere Disease; Vitiligo; Glaucoma; Glaucoma, Open-Angle; Hypertension; Ocular Hypertension Prostanoid FP receptor agonist


Unknown Approved DERMATOLOGY; IMMUNE SYSTEM; OTHER; PEDIATRICS ORAL; TOPICAL Alcoholism; Infections; Leishmaniasis; Triple Negative Breast Neoplasms; Acne Vulgaris; Anosmia; Dengue; Dermatitis, Atopic; Onchocerciasis, Ocular; Severe Dengue; Trichuriasis; Blepharitis; Elephantiasis, Filarial; Influenza, Human; Malaria; Pneumonia; Severe Acute Respiratory Syndrome; Helminthiasis; Lice Infestations; Onchocerciasis; Rosacea; Strongyloidiasis Glutamate-gated chloride channel modulator

Unknown

Approved

DERMATOLOGY; IMMUNE SYSTEM; OTHER; PEDIATRICS

ORAL; TOPICAL

Alcoholism; Infections; Leishmaniasis; Triple Negative Breast Neoplasms; Acne Vulgaris; Anosmia; Dengue; Dermatitis, Atopic; Onchocerciasis, Ocular; Severe Dengue; Trichuriasis; Blepharitis; Elephantiasis, Filarial; Influenza, Human; Malaria; Pneumonia; Severe Acute Respiratory Syndrome; Helminthiasis; Lice Infestations; Onchocerciasis; Rosacea; Strongyloidiasis

Glutamate-gated chloride channel modulator


Unknown Approved OTHER INJECTION Acute Kidney Injury Diagnostic agent


Protein Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER UNKNOWN Stroke; Alzheimer Disease; Asthma; Colitis, Ulcerative; Crohn Disease; Multiple Organ Failure; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Pulmonary Disease, Chronic Obstructive; Hepatitis C; Influenza, Human; Multiple Sclerosis, Relapsing-Remitting; Pneumonia; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Multiple Sclerosis; Neoplasms Interferon alpha/beta receptor agonist

Protein

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

UNKNOWN

Stroke; Alzheimer Disease; Asthma; Colitis, Ulcerative; Crohn Disease; Multiple Organ Failure; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Pulmonary Disease, Chronic Obstructive; Hepatitis C; Influenza, Human; Multiple Sclerosis, Relapsing-Remitting; Pneumonia; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Multiple Sclerosis; Neoplasms

Interferon alpha/beta receptor agonist


Small molecule Approved DERMATOLOGY; OTHER TOPICAL Skin Diseases; Molluscum Contagiosum; Acne Vulgaris Retinoic acid receptor agonist


Antibody Approved OTHER INTRAVENOUS Unknown Diagnostic agent


Antibody Approved OTHER UNKNOWN Unknown Diagnostic (monoclonal antibody that is labelled with Indium (111In) for imaging)


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS ORAL Bulimia Nervosa; Cognitive Dysfunction; Feeding and Eating Disorders; Hernias, Diaphragmatic, Congenital; HIV Infections; Liver Diseases; Alcohol Drinking; Amphetamine-Related Disorders; Brain Ischemia; Deafness; Diabetes Mellitus; Hearing Loss, Sudden; Marijuana Abuse; Multiple Sclerosis; Parkinson Disease; Sciatica; Stress Disorders, Post-Traumatic; Alcoholism; Anxiety; Bipolar Disorder; Bulimia; Cocaine-Related Disorders; Dementia; Depressive Disorder; Diabetes Mellitus, Type 2; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Essential Tremor; Gambling; Headache; Hyperlipidemias; Hypertension; Hypertriglyceridemia; Metabolic Syndrome; Mood Disorders; Obesity; Obsessive-Compulsive Disorder; Pain; Prader-Willi Syndrome; Schizophrenia; Smoking Cessation; Tobacco Use Disorder; Tourette Syndrome; Epilepsy; Lennox Gastaut Syndrome; Migraine Disorders; Seizures Carbonic anhydrase II inhibitor

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS

ORAL

Bulimia Nervosa; Cognitive Dysfunction; Feeding and Eating Disorders; Hernias, Diaphragmatic, Congenital; HIV Infections; Liver Diseases; Alcohol Drinking; Amphetamine-Related Disorders; Brain Ischemia; Deafness; Diabetes Mellitus; Hearing Loss, Sudden; Marijuana Abuse; Multiple Sclerosis; Parkinson Disease; Sciatica; Stress Disorders, Post-Traumatic; Alcoholism; Anxiety; Bipolar Disorder; Bulimia; Cocaine-Related Disorders; Dementia; Depressive Disorder; Diabetes Mellitus, Type 2; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Essential Tremor; Gambling; Headache; Hyperlipidemias; Hypertension; Hypertriglyceridemia; Metabolic Syndrome; Mood Disorders; Obesity; Obsessive-Compulsive Disorder; Pain; Prader-Willi Syndrome; Schizophrenia; Smoking Cessation; Tobacco Use Disorder; Tourette Syndrome; Epilepsy; Lennox Gastaut Syndrome; Migraine Disorders; Seizures

Carbonic anhydrase II inhibitor


Enzyme Approved OTHER SINGLE-USE; UNKNOWN Hematologic Neoplasms; Retinal Vein Occlusion; Thrombophlebitis; Abdominal Abscess; Arterial Occlusive Diseases; Bronchitis; Infections; Macular Degeneration; Neoplasms; Nervous System Diseases; Respiratory Insufficiency; Retinal Hemorrhage; Severe Acute Respiratory Syndrome; Urinary Retention; Venous Thrombosis; Abscess; Angina, Stable; Brain Ischemia; Cardiovascular Diseases; Cerebral Hemorrhage; Cerebral Infarction; Coronary Disease; Empyema; Empyema, Pleural; Hemorrhage; Ischemic Stroke; Myocardial Ischemia; Respiratory Distress Syndrome; Retinal Artery Occlusion; Subarachnoid Hemorrhage; Eye Diseases; Heart Failure; Myocardial Infarction; Pulmonary Embolism; Stroke; Thrombosis Tissue-type plasminogen activator exogenous protein

Enzyme

Approved

OTHER

SINGLE-USE; UNKNOWN

Hematologic Neoplasms; Retinal Vein Occlusion; Thrombophlebitis; Abdominal Abscess; Arterial Occlusive Diseases; Bronchitis; Infections; Macular Degeneration; Neoplasms; Nervous System Diseases; Respiratory Insufficiency; Retinal Hemorrhage; Severe Acute Respiratory Syndrome; Urinary Retention; Venous Thrombosis; Abscess; Angina, Stable; Brain Ischemia; Cardiovascular Diseases; Cerebral Hemorrhage; Cerebral Infarction; Coronary Disease; Empyema; Empyema, Pleural; Hemorrhage; Ischemic Stroke; Myocardial Ischemia; Respiratory Distress Syndrome; Retinal Artery Occlusion; Subarachnoid Hemorrhage; Eye Diseases; Heart Failure; Myocardial Infarction; Pulmonary Embolism; Stroke; Thrombosis

Tissue-type plasminogen activator exogenous protein


Small molecule Approved OTHER; RESPIRATORY ORAL Breast Neoplasms; Hypersensitivity; Ovarian Neoplasms; Asthma; Lung Diseases, Obstructive Cysteinyl leukotriene receptor 1 antagonist


Small molecule Approved OTHER ORAL HIV Infections; Alzheimer Disease; Dermatitis; Melanoma; Psoriasis Retinoid receptor agonist


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Breast Neoplasms; Obesity; Substance-Related Disorders; Cocaine-Related Disorders; Endometriosis; Infertility; Paget Disease, Extramammary; Pituitary ACTH Hypersecretion; Polycystic Ovary Syndrome; Diabetes Mellitus; Ovarian Hyperstimulation Syndrome; Restless Legs Syndrome; Parkinson Disease; Pituitary Neoplasms Dopamine D2 receptor agonist

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER

ORAL

Breast Neoplasms; Obesity; Substance-Related Disorders; Cocaine-Related Disorders; Endometriosis; Infertility; Paget Disease, Extramammary; Pituitary ACTH Hypersecretion; Polycystic Ovary Syndrome; Diabetes Mellitus; Ovarian Hyperstimulation Syndrome; Restless Legs Syndrome; Parkinson Disease; Pituitary Neoplasms

Dopamine D2 receptor agonist


Small molecule Approved CANCER; OTHER; PREGNANCY AND GYNECOLOGY INJECTION; INTRAVENOUS Breast Neoplasms, Male; Carcinoma, Endometrioid; Carcinoma, Renal Cell; Colonic Neoplasms; Cystadenoma, Serous; Digestive System Diseases; Lymphoma; Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Nausea; Neoplasms, Plasma Cell; Sarcoma, Synovial; Vaginal Neoplasms; Vulvar Neoplasms; Biliary Tract Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Large Cell; Carcinoma, Neuroendocrine; Carcinoma, Ovarian Epithelial; Carcinoma, Transitional Cell; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Hereditary Breast and Ovarian Cancer Syndrome; Leiomyosarcoma; Leukemia; Liver Neoplasms; Mediastinal Neoplasms; Melanoma; Osteosarcoma; Pancreatic Neoplasms; Penile Neoplasms; Retroviridae Infections; Salivary Gland Neoplasms; Sarcoma, Ewing; Small Cell Lung Carcinoma; Testicular Neoplasms; Thyroid Carcinoma, Anaplastic; Tonsillar Neoplasms; Triple Negative Breast Neoplasms; Urethral Neoplasms; Uterine Neoplasms; Adenocarcinoma of Lung; Anorexia; Cachexia; Carcinoma; Carcinoma, Squamous Cell; Endometrial Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Fatigue; Genital Neoplasms, Male; Hypersensitivity; Hypopharyngeal Neoplasms; Inflammatory Breast Neoplasms; Kidney Neoplasms; Laryngeal Neoplasms; Lung Neoplasms; Mouth Neoplasms; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neutropenia; Oropharyngeal Neoplasms; Ovarian Neoplasms; Paranasal Sinus Neoplasms; Peritoneal Neoplasms; Pharyngeal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Squamous Cell Carcinoma of Head and Neck; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Adenocarcinoma; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Head and Neck Neoplasms; Neoplasms; Prostatic Neoplasms; Stomach Neoplasms Tubulin inhibitor

Small molecule

Approved

CANCER; OTHER; PREGNANCY AND GYNECOLOGY

INJECTION; INTRAVENOUS

Breast Neoplasms, Male; Carcinoma, Endometrioid; Carcinoma, Renal Cell; Colonic Neoplasms; Cystadenoma, Serous; Digestive System Diseases; Lymphoma; Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Nausea; Neoplasms, Plasma Cell; Sarcoma, Synovial; Vaginal Neoplasms; Vulvar Neoplasms; Biliary Tract Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Large Cell; Carcinoma, Neuroendocrine; Carcinoma, Ovarian Epithelial; Carcinoma, Transitional Cell; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Hereditary Breast and Ovarian Cancer Syndrome; Leiomyosarcoma; Leukemia; Liver Neoplasms; Mediastinal Neoplasms; Melanoma; Osteosarcoma; Pancreatic Neoplasms; Penile Neoplasms; Retroviridae Infections; Salivary Gland Neoplasms; Sarcoma, Ewing; Small Cell Lung Carcinoma; Testicular Neoplasms; Thyroid Carcinoma, Anaplastic; Tonsillar Neoplasms; Triple Negative Breast Neoplasms; Urethral Neoplasms; Uterine Neoplasms; Adenocarcinoma of Lung; Anorexia; Cachexia; Carcinoma; Carcinoma, Squamous Cell; Endometrial Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Fatigue; Genital Neoplasms, Male; Hypersensitivity; Hypopharyngeal Neoplasms; Inflammatory Breast Neoplasms; Kidney Neoplasms; Laryngeal Neoplasms; Lung Neoplasms; Mouth Neoplasms; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neutropenia; Oropharyngeal Neoplasms; Ovarian Neoplasms; Paranasal Sinus Neoplasms; Peritoneal Neoplasms; Pharyngeal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Squamous Cell Carcinoma of Head and Neck; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Adenocarcinoma; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Head and Neck Neoplasms; Neoplasms; Prostatic Neoplasms; Stomach Neoplasms

Tubulin inhibitor


Unknown Approved OTHER INJECTION Unknown Unknown


Small molecule Approved OTHER INJECTION Brain Neoplasms; Diffuse Intrinsic Pontine Glioma; Leukemia; Leukemia, Myeloid, Acute; Lymphoma, T-Cell, Cutaneous; Sarcoma, Synovial; Stomach Neoplasms; Adenocarcinoma; Adenocarcinoma of Lung; Anxiety; Bile Duct Neoplasms; Biliary Tract Diseases; Bone Neoplasms; Carcinoma, Large Cell; Carcinoma, Ovarian Epithelial; Carcinoma, Renal Cell; Colonic Neoplasms; Colorectal Neoplasms; Digestive System Diseases; Endometrial Neoplasms; Esophageal Neoplasms; Esthesioneuroblastoma, Olfactory; Gastrointestinal Stromal Tumors; Glioma; Head and Neck Neoplasms; Kidney Neoplasms; Leiomyosarcoma; Leukemia-Lymphoma, Adult T-Cell; Liver Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, T-Cell; Medulloblastoma; Melanoma; Multiple Myeloma; Neoplasms, Germ Cell and Embryonal; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Sarcoma, Ewing; Small Cell Lung Carcinoma; Testicular Neoplasms; Thyroid Neoplasms; Urethral Neoplasms; Biliary Tract Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cholangiocarcinoma; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Genital Neoplasms, Female; Granuloma, Lethal Midline; Hepatoblastoma; Hernia; Hernia, Ventral; Hodgkin Disease; Immunoblastic Lymphadenopathy; Lung Neoplasms; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Mesothelioma; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Sarcoma; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Neoplasms Unknown

Small molecule

Approved

OTHER

INJECTION

Brain Neoplasms; Diffuse Intrinsic Pontine Glioma; Leukemia; Leukemia, Myeloid, Acute; Lymphoma, T-Cell, Cutaneous; Sarcoma, Synovial; Stomach Neoplasms; Adenocarcinoma; Adenocarcinoma of Lung; Anxiety; Bile Duct Neoplasms; Biliary Tract Diseases; Bone Neoplasms; Carcinoma, Large Cell; Carcinoma, Ovarian Epithelial; Carcinoma, Renal Cell; Colonic Neoplasms; Colorectal Neoplasms; Digestive System Diseases; Endometrial Neoplasms; Esophageal Neoplasms; Esthesioneuroblastoma, Olfactory; Gastrointestinal Stromal Tumors; Glioma; Head and Neck Neoplasms; Kidney Neoplasms; Leiomyosarcoma; Leukemia-Lymphoma, Adult T-Cell; Liver Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, T-Cell; Medulloblastoma; Melanoma; Multiple Myeloma; Neoplasms, Germ Cell and Embryonal; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Sarcoma, Ewing; Small Cell Lung Carcinoma; Testicular Neoplasms; Thyroid Neoplasms; Urethral Neoplasms; Biliary Tract Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cholangiocarcinoma; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Genital Neoplasms, Female; Granuloma, Lethal Midline; Hepatoblastoma; Hernia; Hernia, Ventral; Hodgkin Disease; Immunoblastic Lymphadenopathy; Lung Neoplasms; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Mesothelioma; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Sarcoma; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Neoplasms

Unknown


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Cardiovascular Diseases; Heart Failure; Hypertension; Myocardial Infarction; Ventricular Dysfunction, Left Angiotensin-converting enzyme inhibitor


Small molecule Approved OTHER; RESPIRATORY ORAL Anemia, Sickle Cell; Inflammation; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Acne Vulgaris; Idiopathic Pulmonary Fibrosis; Lung Neoplasms; Tobacco Use Disorder; Pulmonary Disease, Chronic Obstructive; Asthma Arachidonate 5-lipoxygenase inhibitor


Small molecule Approved IMMUNE SYSTEM; OTHER; PHARMACOLOGY ORAL Unknown Bacterial DNA gyrase inhibitor

Antibody

Approved

HEMATOLOGY; OTHER

UNKNOWN

Arthritis, Psoriatic; Autoimmune Diseases; Carcinoma, Squamous Cell; Crohn Disease; Encephalomyelitis; Fanconi Anemia; Gangliosidoses; Glycogen Storage Disease Type II; Gout; Graves Disease; Hematologic Diseases; Liver Cirrhosis, Biliary; Lymphoma, Primary Effusion; Lymphoma, T-Cell, Cutaneous; Macular Degeneration; Muscular Diseases; Mycosis Fungoides; Neuroblastoma; Opsoclonus-Myoclonus Syndrome; Pemphigoid, Benign Mucous Membrane; Prostatic Neoplasms, Castration-Resistant; Renal Insufficiency, Chronic; Scleritis; Urticaria; Acquired Immunodeficiency Syndrome; Anemia, Aplastic; Anemia, Sickle Cell; Behcet Syndrome; Blast Crisis; Blastic Plasmacytoid Dendritic Cell Neoplasm; Breast Neoplasms; Bronchiolitis Obliterans Syndrome; Carcinoma, Hepatocellular; Castleman Disease; Churg-Strauss Syndrome; Colitis, Ulcerative; Colonic Neoplasms; Dermatomyositis; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Encephalitis, Japanese; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Graves Ophthalmopathy; Heart Failure; Hematologic Neoplasms; Hemolytic-Uremic Syndrome; Hemophilia A; Histiocytosis, Langerhans-Cell; HTLV-I Infections; Idiopathic Pulmonary Fibrosis; Immunoblastic Lymphadenopathy; Kidney Failure, Chronic; Leukemia, Biphenotypic, Acute; Leukemia, Hairy Cell; Leukemia, Mast-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Leukemia, Prolymphocytic; Lung Neoplasms; Lymphoma, AIDS-Related; Lymphoma, B-Cell; Lymphoma, Large-Cell, Anaplastic; Lymphoproliferative Disorders; Melanoma; Multiple Myeloma; Multiple Sclerosis, Chronic Progressive; Myelodysplastic Syndromes; Neoplasms, Plasma Cell; Neuromyelitis Optica; Pancreatic Neoplasms; Peripheral Nervous System Diseases; Pneumococcal Infections; Polyendocrinopathies, Autoimmune; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Psychotic Disorders; Pulmonary Alveolar Proteinosis; Renal Insufficiency; Rheumatic Heart Disease; Sarcoidosis; Schizophrenia; Scleroderma, Systemic; Sjogren's Syndrome; Spinal Cord Diseases; Spondylitis, Ankylosing; Stiff-Person Syndrome; Stomach Neoplasms; Virus Diseases; Anemia, Hemolytic, Autoimmune; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Burkitt Lymphoma; Fatigue Syndrome, Chronic; Glomerulonephritis, Membranoproliferative; Glomerulonephritis, Membranous; Graft vs Host Disease; Hodgkin Disease; IgA Vasculitis; Immune System Diseases; Kidney Diseases; Leukemia; Leukemia, Lymphoid; Lung Diseases; Lung Diseases, Interstitial; Lupus Erythematosus, Systemic; Lupus Nephritis; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Mental Disorders; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Myasthenia Gravis; Nephrotic Syndrome; Pemphigoid, Bullous; Polymyalgia Rheumatica; Polyneuropathies; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Proteinuria; Purpura, Thrombocytopenic, Idiopathic; Purpura, Thrombotic Thrombocytopenic; Waldenstrom Macroglobulinemia; Arthritis, Rheumatoid; Granulomatosis with Polyangiitis; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Microscopic Polyangiitis; Neoplasms; Pemphigus; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Systemic Vasculitis

B-lymphocyte antigen CD20 binding agent

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER

ORAL

Anemia, Sickle Cell; Arthritis, Rheumatoid; Gastrointestinal Stromal Tumors; Malaria; Mitochondrial Diseases; Neoplasms; Parkinson Disease; Prostatic Neoplasms, Castration-Resistant; Atherosclerosis; Coronary Disease; Cystic Fibrosis; Hypercholesterolemia; Hypertension; Diabetes Mellitus; Diabetes Mellitus, Type 2

Sulfonylurea receptor 1, Kir6.2 blocker

Protein

Approved

OTHER

INJECTION

Central Nervous System Neoplasms; Heart Failure, Systolic; Hypotension, Orthostatic; Neoplasms; Sarcoma; Subarachnoid Hemorrhage; Adenocarcinoma; Adenocarcinoma of Lung; Adrenoleukodystrophy; alpha 1-Antitrypsin Deficiency; Amyotrophic Lateral Sclerosis; Burns; Carcinoma, Squamous Cell; Cerebral Hemorrhage; Cerebral Infarction; Craniocerebral Trauma; Esophageal Neoplasms; Graft vs Host Disease; Inflammation; Kidney Diseases; Macular Degeneration; Multiple Sclerosis, Relapsing-Remitting; Pneumonia; Scleroderma, Systemic; Shock; Abortion, Habitual; Alzheimer Disease; Ascites; Breast Neoplasms; Carcinoma, Hepatocellular; Edema; Endometrial Neoplasms; Ischemic Stroke; Liver Cirrhosis; Orthostatic Intolerance; Pancreatic Neoplasms; Paraganglioma; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Pulmonary Disease, Chronic Obstructive; Sepsis; Shock, Septic; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Nephrosis; Respiratory Distress Syndrome

Bilirubin sequestering agent


Small molecule Approved OTHER INJECTION Bacterial Infections Bacterial DNA gyrase inhibitor

Small molecule

Approved

OTHER; PREGNANCY AND GYNECOLOGY

ORAL

Brain Neoplasms; Carcinoma, Endometrioid; Carcinoma, Non-Small-Cell Lung; Leiomyoma; Lymphoma, Non-Hodgkin; Mesothelioma; Pregnancy, Ectopic; Adenomyosis; Anovulation; Carcinoma; Carcinoma, Lobular; Dwarfism; Endometriosis; Fallopian Tube Neoplasms; Hemangiosarcoma; Hermanski-Pudlak Syndrome; Infertility, Male; Inflammatory Breast Neoplasms; Leiomyosarcoma; Liver Neoplasms; Lymphangioleiomyomatosis; Peritoneal Neoplasms; Triple Negative Breast Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Abortion, Spontaneous; Azoospermia; Carcinoma, Intraductal, Noninfiltrating; Endometrial Neoplasms; Follicular Cyst; Hereditary Breast and Ovarian Cancer Syndrome; Hypogonadism; Infertility; Menopause; Neoplasm Metastasis; Osteoporosis; Ovarian Hyperstimulation Syndrome; Ovarian Neoplasms; Polycystic Ovary Syndrome; Pregnancy; Breast Neoplasms; Neoplasms

Cytochrome P450 19A1 inhibitor


Small molecule Approved OTHER ORAL Sarcoma; Diabetes Mellitus Peroxisome proliferator-activated receptor gamma agonist


Small molecule Approved ENT; OTHER; PHARMACOLOGY; RESPIRATORY ORAL Appendicitis; Osteomyelitis; Mastitis; Bacterial Infections; Bronchitis, Chronic; Infections; Otitis Media; Pharyngitis; Pneumonia; Tonsillitis Bacterial penicillin-binding protein inhibitor

Small molecule

Approved

DERMATOLOGY; IMMUNE SYSTEM; OTHER

TOPICAL

Astrocytoma; Brain Neoplasms; Carcinoma, Squamous Cell; Cheilitis; Colorectal Neoplasms; Diffuse Intrinsic Pontine Glioma; Ependymoma; Glioblastoma; Glioma; Influenza in Birds; Lymphoma, T-Cell, Cutaneous; Malaria, Falciparum; Medulloblastoma; Mouth Neoplasms; Mycosis Fungoides; Neoplasms; Osteosarcoma; Paraganglioma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Bowen's Disease; Breast Neoplasms; Carcinoma in Situ; Carcinoma, Non-Small-Cell Lung; Hemangioma; Hepatitis B, Chronic; Keloid; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Liver Cirrhosis; Melanoma; Port-Wine Stain; Renal Insufficiency; Uterine Cervical Neoplasms; Influenza, Human; Leishmaniasis, Cutaneous; Paget Disease, Extramammary; Papillomavirus Infections; Scleroderma, Localized; Squamous Intraepithelial Lesions; Uterine Cervical Dysplasia; Vulvar Neoplasms; Carcinoma, Basal Cell; Condylomata Acuminata; Keratosis; Keratosis, Actinic; Virus Diseases

Toll-like receptor 7 agonist


Small molecule Approved OTHER TOPICAL Skin Diseases Glucocorticoid receptor agonist