DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 1496


Oligosaccharide Approved CARDIOVASCULAR; OTHER INJECTION Unknown Antithrombin-III activator


Small molecule Approved OTHER TOPICAL Adrenal Hyperplasia, Congenital; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Bursitis; Colitis, Ulcerative; Conjunctivitis, Allergic; Dermatitis; Dermatitis, Atopic; Dermatitis, Seborrheic; Endocrine System Diseases; Exanthema; Inflammation; Leukemia; Lymphoma; Neoplasms; Osteoarthritis; Pruritus; Psoriasis; Serum Sickness; Skin Diseases; Spondylitis; Tenosynovitis Glucocorticoid receptor agonist

Small molecule

Approved

OTHER

TOPICAL

Adrenal Hyperplasia, Congenital; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Bursitis; Colitis, Ulcerative; Conjunctivitis, Allergic; Dermatitis; Dermatitis, Atopic; Dermatitis, Seborrheic; Endocrine System Diseases; Exanthema; Inflammation; Leukemia; Lymphoma; Neoplasms; Osteoarthritis; Pruritus; Psoriasis; Serum Sickness; Skin Diseases; Spondylitis; Tenosynovitis

Glucocorticoid receptor agonist


Small molecule Approved OTHER OPHTHALMIC Unknown Histamine H1 receptor antagonist


Small molecule Approved OTHER ORAL Lecithin Cholesterol Acyltransferase Deficiency; Multiple Sclerosis; Alcoholism; Anxiety; Anxiety Disorders; Borderline Personality Disorder; Dementia; Depressive Disorder; Neurotic Disorders; Obsessive-Compulsive Disorder; Phobia, Social; Psychomotor Agitation; Psychotic Disorders; Stress Disorders, Post-Traumatic; Bipolar Disorder; Depressive Disorder, Major; Schizophrenia Dopamine D2 receptor antagonist

Small molecule

Approved

OTHER

ORAL

Lecithin Cholesterol Acyltransferase Deficiency; Multiple Sclerosis; Alcoholism; Anxiety; Anxiety Disorders; Borderline Personality Disorder; Dementia; Depressive Disorder; Neurotic Disorders; Obsessive-Compulsive Disorder; Phobia, Social; Psychomotor Agitation; Psychotic Disorders; Stress Disorders, Post-Traumatic; Bipolar Disorder; Depressive Disorder, Major; Schizophrenia

Dopamine D2 receptor antagonist


Small molecule Approved OTHER; PHARMACOLOGY INJECTION Macular Degeneration Alcohol dehydrogenase class I inhibitor


Small molecule Approved OTHER ORAL Sarcoma; Diabetes Mellitus Peroxisome proliferator-activated receptor gamma agonist


Small molecule Approved IMMUNE SYSTEM; OTHER; PHARMACOLOGY ORAL Unknown Bacterial DNA gyrase inhibitor


Small molecule Approved OTHER OPHTHALMIC Central Serous Chorioretinopathy; Glaucoma; Glaucoma, Open-Angle; Ocular Hypertension Carbonic anhydrase II inhibitor


Small molecule Approved DERMATOLOGY; OTHER ORAL Endometriosis; Epilepsy; Scleroderma, Systemic; Acquired Immunodeficiency Syndrome; Alzheimer Disease; Amyloidosis; Amyotrophic Lateral Sclerosis; Appendiceal Neoplasms; Brain Stem Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Castleman Disease; Central Nervous System Neoplasms; Cholangitis, Sclerosing; Colonic Neoplasms; Esophageal Neoplasms; Glioblastoma; Glioma; Head and Neck Neoplasms; Hepatitis C; Histiocytosis, Langerhans-Cell; HIV Infections; HIV Wasting Syndrome; Hodgkin Disease; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Liver Neoplasms; Lupus Erythematosus, Discoid; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Medulloblastoma; Melanoma; Mouth Neoplasms; Neuroblastoma; Neuroendocrine Tumors; Pain; Pancreatitis, Chronic; Primary Myelofibrosis; Proctitis; Prostatic Neoplasms; Psoriasis; Purpura, Thrombocytopenic, Idiopathic; Retroviridae Infections; Sarcoma; Severe Acute Respiratory Syndrome; Spondylitis, Ankylosing; Thalassemia; Waldenstrom Macroglobulinemia; Amyloidosis, Familial; Carcinoma, Hepatocellular; Colitis, Ulcerative; Colorectal Neoplasms; Cough; Crohn Disease; Fallopian Tube Neoplasms; Granuloma, Lethal Midline; Hypoalbuminemia; Idiopathic Pulmonary Fibrosis; Kidney Neoplasms; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Myelodysplastic Syndromes; Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoidosis; Vascular Malformations; Immune System Diseases; Multiple Myeloma CRL4(CRBN) E3 ubiquitin ligase inhibitor

Small molecule

Approved

DERMATOLOGY; OTHER

ORAL

Endometriosis; Epilepsy; Scleroderma, Systemic; Acquired Immunodeficiency Syndrome; Alzheimer Disease; Amyloidosis; Amyotrophic Lateral Sclerosis; Appendiceal Neoplasms; Brain Stem Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Castleman Disease; Central Nervous System Neoplasms; Cholangitis, Sclerosing; Colonic Neoplasms; Esophageal Neoplasms; Glioblastoma; Glioma; Head and Neck Neoplasms; Hepatitis C; Histiocytosis, Langerhans-Cell; HIV Infections; HIV Wasting Syndrome; Hodgkin Disease; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Liver Neoplasms; Lupus Erythematosus, Discoid; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Medulloblastoma; Melanoma; Mouth Neoplasms; Neuroblastoma; Neuroendocrine Tumors; Pain; Pancreatitis, Chronic; Primary Myelofibrosis; Proctitis; Prostatic Neoplasms; Psoriasis; Purpura, Thrombocytopenic, Idiopathic; Retroviridae Infections; Sarcoma; Severe Acute Respiratory Syndrome; Spondylitis, Ankylosing; Thalassemia; Waldenstrom Macroglobulinemia; Amyloidosis, Familial; Carcinoma, Hepatocellular; Colitis, Ulcerative; Colorectal Neoplasms; Cough; Crohn Disease; Fallopian Tube Neoplasms; Granuloma, Lethal Midline; Hypoalbuminemia; Idiopathic Pulmonary Fibrosis; Kidney Neoplasms; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Myelodysplastic Syndromes; Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoidosis; Vascular Malformations; Immune System Diseases; Multiple Myeloma

CRL4(CRBN) E3 ubiquitin ligase inhibitor


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER; UROLOGY AND KIDNEY INJECTION; INTRAVENOUS; ORAL Breast Neoplasms; Multiple Myeloma; Neoplasms; Rectal Neoplasms; Carcinoma, Pancreatic Ductal; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Hypocalcemia; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Albuminuria; Glomerulonephritis, IGA; Hyperparathyroidism; Hypertrophy, Left Ventricular; Kidney Diseases; Proteinuria; Hyperparathyroidism, Secondary; Parathyroid Diseases; Renal Insufficiency, Chronic Vitamin D receptor agonist

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER; UROLOGY AND KIDNEY

INJECTION; INTRAVENOUS; ORAL

Breast Neoplasms; Multiple Myeloma; Neoplasms; Rectal Neoplasms; Carcinoma, Pancreatic Ductal; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Hypocalcemia; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Albuminuria; Glomerulonephritis, IGA; Hyperparathyroidism; Hypertrophy, Left Ventricular; Kidney Diseases; Proteinuria; Hyperparathyroidism, Secondary; Parathyroid Diseases; Renal Insufficiency, Chronic

Vitamin D receptor agonist


Antibody Approved OTHER; RESPIRATORY UNKNOWN Hernias, Diaphragmatic, Congenital; Respiratory Syncytial Virus Infections; Bronchopulmonary Dysplasia; Respiratory Tract Diseases Fusion glycoprotein F0 inhibitor


Antibody Approved DIABETES DRUGS & ENDOCRINOLOGY; IMMUNE SYSTEM; OTHER SINGLE-USE DiGeorge Syndrome; Kidney Tubular Necrosis, Acute; Leukemia, Myeloid, Acute; Multiple Myeloma; Neoplasms; Uremia; Amyotrophic Lateral Sclerosis; Colitis, Ulcerative; Glioblastoma; Glomerulosclerosis, Focal Segmental; Granuloma, Lethal Midline; Hodgkin Disease; Kidney Diseases; Renal Insufficiency, Chronic; Uveitis; Diabetes Mellitus, Type 1; Emphysema; Graft vs Host Disease; Infections; Reperfusion Injury; Immune System Diseases Interleukin-2 receptor inhibitor

Antibody

Approved

DIABETES DRUGS & ENDOCRINOLOGY; IMMUNE SYSTEM; OTHER

SINGLE-USE

DiGeorge Syndrome; Kidney Tubular Necrosis, Acute; Leukemia, Myeloid, Acute; Multiple Myeloma; Neoplasms; Uremia; Amyotrophic Lateral Sclerosis; Colitis, Ulcerative; Glioblastoma; Glomerulosclerosis, Focal Segmental; Granuloma, Lethal Midline; Hodgkin Disease; Kidney Diseases; Renal Insufficiency, Chronic; Uveitis; Diabetes Mellitus, Type 1; Emphysema; Graft vs Host Disease; Infections; Reperfusion Injury; Immune System Diseases

Interleukin-2 receptor inhibitor


Small molecule Approved OTHER; PREGNANCY AND GYNECOLOGY ORAL Sleep Apnea, Obstructive; Alzheimer Disease; HIV Infections; Albuminuria; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Essential Hypertension; Heart Diseases; Lipid Metabolism Disorders; Polycystic Kidney Diseases; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; Cardiovascular Diseases; Diabetes Mellitus; Hypertension; Myocardial Infarction; Stroke Type-1 angiotensin II receptor antagonist

Small molecule

Approved

OTHER; PREGNANCY AND GYNECOLOGY

ORAL

Sleep Apnea, Obstructive; Alzheimer Disease; HIV Infections; Albuminuria; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Essential Hypertension; Heart Diseases; Lipid Metabolism Disorders; Polycystic Kidney Diseases; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; Cardiovascular Diseases; Diabetes Mellitus; Hypertension; Myocardial Infarction; Stroke

Type-1 angiotensin II receptor antagonist


Small molecule Approved OTHER ORAL Cognitive Dysfunction; Hypotension, Orthostatic; Melanoma; Psychotic Disorders; Sleep Apnea Syndromes; Sleep Initiation and Maintenance Disorders; Tinnitus; Tobacco Use Disorder; Alcoholism; Amphetamine-Related Disorders; Deglutition Disorders; Depressive Disorder; Opioid-Related Disorders; Ovarian Neoplasms; Parkinson Disease; Schizophrenia; Stress Disorders, Post-Traumatic; Substance-Related Disorders; Alzheimer Disease; Brain Neoplasms; Cocaine-Related Disorders; Depressive Disorder, Major; Fatigue; Multiple Sclerosis; Narcolepsy; Postpoliomyelitis Syndrome; Sarcoma, Ewing; Sleep Apnea, Obstructive; Sleep Wake Disorders; Stroke; Attention Deficit Disorder with Hyperactivity Dopamine transporter inhibitor

Small molecule

Approved

OTHER

ORAL

Cognitive Dysfunction; Hypotension, Orthostatic; Melanoma; Psychotic Disorders; Sleep Apnea Syndromes; Sleep Initiation and Maintenance Disorders; Tinnitus; Tobacco Use Disorder; Alcoholism; Amphetamine-Related Disorders; Deglutition Disorders; Depressive Disorder; Opioid-Related Disorders; Ovarian Neoplasms; Parkinson Disease; Schizophrenia; Stress Disorders, Post-Traumatic; Substance-Related Disorders; Alzheimer Disease; Brain Neoplasms; Cocaine-Related Disorders; Depressive Disorder, Major; Fatigue; Multiple Sclerosis; Narcolepsy; Postpoliomyelitis Syndrome; Sarcoma, Ewing; Sleep Apnea, Obstructive; Sleep Wake Disorders; Stroke; Attention Deficit Disorder with Hyperactivity

Dopamine transporter inhibitor


Small molecule Approved OTHER ORAL Depressive Disorder, Major; Obesity; Breast Carcinoma In Situ; Carcinoma, Hepatocellular; Hepatolenticular Degeneration; Hypotension, Orthostatic; Inflammation; Keratosis, Actinic; Mouth Neoplasms; Myeloproliferative Disorders; Neuroblastoma; Tuberculosis; Uterine Cervical Neoplasms; Amyotrophic Lateral Sclerosis; Back Pain; Brain Neoplasms; Carcinoma, Renal Cell; Central Nervous System Neoplasms; Cervical Intraepithelial Neoplasia; Esophageal Neoplasms; Facial Pain; Glioblastoma; Glioma; Graves Ophthalmopathy; Lymphangioleiomyomatosis; Medulloblastoma; Melanoma; Multiple Myeloma; Muscular Atrophy, Spinal; Neuralgia; Neurofibromatosis 1; Obsessive-Compulsive Disorder; Ovarian Neoplasms; Papilloma; Papillomavirus Infections; Paraproteinemias; Peritoneal Neoplasms; Pre-Eclampsia; Prostatic Hyperplasia; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rotator Cuff Injuries; Sarcoma; Schizophrenia; Severe Acute Respiratory Syndrome; Squamous Cell Carcinoma of Head and Neck; Squamous Intraepithelial Lesions; Stomatitis; Temporomandibular Joint Disorders; Tonsillitis; Toothache; Urinary Bladder Neoplasms; Uterine Neoplasms; Adenoma; Alzheimer Disease; Bipolar Disorder; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Chronic Pain; Colonic Neoplasms; Colorectal Neoplasms; Depression, Postpartum; Depressive Disorder; Gout; Hand-Foot Syndrome; Head and Neck Neoplasms; Hypertension; Influenza, Human; Liver Neoplasms; Low Back Pain; Lung Neoplasms; Macular Degeneration; Memory Disorders; Nasopharyngeal Neoplasms; Osteoarthritis, Hip; Osteoarthritis, Knee; Pancreatic Neoplasms; Pharyngitis; Rectal Neoplasms; Tobacco Use Disorder; Wounds and Injuries; Acute Pain; Adenomatous Polyposis Coli; Arthritis, Juvenile; Arthritis, Rheumatoid; Dysmenorrhea; Hemorrhage; Migraine Disorders; Neoplasms; Osteoarthritis; Pain; Peptic Ulcer; Rheumatic Diseases; Spondylitis; Spondylitis, Ankylosing; Stroke Cyclooxygenase-2 inhibitor

Small molecule

Approved

OTHER

ORAL

Depressive Disorder, Major; Obesity; Breast Carcinoma In Situ; Carcinoma, Hepatocellular; Hepatolenticular Degeneration; Hypotension, Orthostatic; Inflammation; Keratosis, Actinic; Mouth Neoplasms; Myeloproliferative Disorders; Neuroblastoma; Tuberculosis; Uterine Cervical Neoplasms; Amyotrophic Lateral Sclerosis; Back Pain; Brain Neoplasms; Carcinoma, Renal Cell; Central Nervous System Neoplasms; Cervical Intraepithelial Neoplasia; Esophageal Neoplasms; Facial Pain; Glioblastoma; Glioma; Graves Ophthalmopathy; Lymphangioleiomyomatosis; Medulloblastoma; Melanoma; Multiple Myeloma; Muscular Atrophy, Spinal; Neuralgia; Neurofibromatosis 1; Obsessive-Compulsive Disorder; Ovarian Neoplasms; Papilloma; Papillomavirus Infections; Paraproteinemias; Peritoneal Neoplasms; Pre-Eclampsia; Prostatic Hyperplasia; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rotator Cuff Injuries; Sarcoma; Schizophrenia; Severe Acute Respiratory Syndrome; Squamous Cell Carcinoma of Head and Neck; Squamous Intraepithelial Lesions; Stomatitis; Temporomandibular Joint Disorders; Tonsillitis; Toothache; Urinary Bladder Neoplasms; Uterine Neoplasms; Adenoma; Alzheimer Disease; Bipolar Disorder; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Chronic Pain; Colonic Neoplasms; Colorectal Neoplasms; Depression, Postpartum; Depressive Disorder; Gout; Hand-Foot Syndrome; Head and Neck Neoplasms; Hypertension; Influenza, Human; Liver Neoplasms; Low Back Pain; Lung Neoplasms; Macular Degeneration; Memory Disorders; Nasopharyngeal Neoplasms; Osteoarthritis, Hip; Osteoarthritis, Knee; Pancreatic Neoplasms; Pharyngitis; Rectal Neoplasms; Tobacco Use Disorder; Wounds and Injuries; Acute Pain; Adenomatous Polyposis Coli; Arthritis, Juvenile; Arthritis, Rheumatoid; Dysmenorrhea; Hemorrhage; Migraine Disorders; Neoplasms; Osteoarthritis; Pain; Peptic Ulcer; Rheumatic Diseases; Spondylitis; Spondylitis, Ankylosing; Stroke

Cyclooxygenase-2 inhibitor


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER; RHEUMATOLOGY ORAL Breast Neoplasms; Graft vs Host Disease; HIV Infections; Melanoma; Severe Acute Respiratory Syndrome; Lupus Erythematosus, Systemic; Lymphoproliferative Disorders; Multiple Myeloma; Pemphigoid, Bullous; Prostatic Neoplasms, Castration-Resistant; Purpura, Schoenlein-Henoch; Smoldering Multiple Myeloma; Uveitis; Arthritis, Psoriatic; Central Nervous System Neoplasms; Lupus Nephritis; Myasthenia Gravis; Polymyalgia Rheumatica; Arthritis, Rheumatoid; Immune System Diseases; Multiple Sclerosis Dihydroorotate dehydrogenase inhibitor

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER; RHEUMATOLOGY

ORAL

Breast Neoplasms; Graft vs Host Disease; HIV Infections; Melanoma; Severe Acute Respiratory Syndrome; Lupus Erythematosus, Systemic; Lymphoproliferative Disorders; Multiple Myeloma; Pemphigoid, Bullous; Prostatic Neoplasms, Castration-Resistant; Purpura, Schoenlein-Henoch; Smoldering Multiple Myeloma; Uveitis; Arthritis, Psoriatic; Central Nervous System Neoplasms; Lupus Nephritis; Myasthenia Gravis; Polymyalgia Rheumatica; Arthritis, Rheumatoid; Immune System Diseases; Multiple Sclerosis

Dihydroorotate dehydrogenase inhibitor


Enzyme Approved OTHER ORAL Unknown Sucrose hydrolytic enzyme


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Cocaine-Related Disorders; Neuroblastoma; Alcoholism; Brain Injuries; Gambling; Obsessive-Compulsive Disorder; Pick Disease of the Brain; Schizophrenia; Tobacco Use Disorder; Liver Failure; Parkinson Disease Catechol O-methyltransferase inhibitor


Protein Approved OTHER; RHEUMATOLOGY SUBCUTANEOUS; UNKNOWN Fanconi Anemia; Myositis, Inclusion Body; HIV Infections; Leukemia, Lymphocytic, Chronic, B-Cell; Myelodysplastic Syndromes; Neoplasms; Persian Gulf Syndrome; Prostatic Neoplasms, Castration-Resistant; Sciatica; Subarachnoid Hemorrhage; Alzheimer Disease; Amyloidosis; Asthma; Dermatomyositis; Granulomatosis with Polyangiitis; Hidradenitis Suppurativa; Histiocytosis; Leukemia; Lichen Planus; Lupus Erythematosus, Cutaneous; Lupus Nephritis; Metabolic Syndrome; Mucocutaneous Lymph Node Syndrome; Pemphigus; Pulmonary Disease, Chronic Obstructive; Pulmonary Fibrosis; Radiculopathy; Renal Insufficiency, Chronic; Reperfusion Injury; Sjogren's Syndrome; Stomatitis; Synovitis; Temporomandibular Joint Disorders; Tinnitus; Urticaria; Vitiligo; Anorexia; Arthritis; Cachexia; Diabetes Mellitus, Type 1; Graft vs Host Disease; Inflammation; Pneumonia; Polymyalgia Rheumatica; Stevens-Johnson Syndrome; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Immune System Diseases; Psoriasis; Spondylitis; Spondylitis, Ankylosing TNF-alpha inhibitor

Protein

Approved

OTHER; RHEUMATOLOGY

SUBCUTANEOUS; UNKNOWN

Fanconi Anemia; Myositis, Inclusion Body; HIV Infections; Leukemia, Lymphocytic, Chronic, B-Cell; Myelodysplastic Syndromes; Neoplasms; Persian Gulf Syndrome; Prostatic Neoplasms, Castration-Resistant; Sciatica; Subarachnoid Hemorrhage; Alzheimer Disease; Amyloidosis; Asthma; Dermatomyositis; Granulomatosis with Polyangiitis; Hidradenitis Suppurativa; Histiocytosis; Leukemia; Lichen Planus; Lupus Erythematosus, Cutaneous; Lupus Nephritis; Metabolic Syndrome; Mucocutaneous Lymph Node Syndrome; Pemphigus; Pulmonary Disease, Chronic Obstructive; Pulmonary Fibrosis; Radiculopathy; Renal Insufficiency, Chronic; Reperfusion Injury; Sjogren's Syndrome; Stomatitis; Synovitis; Temporomandibular Joint Disorders; Tinnitus; Urticaria; Vitiligo; Anorexia; Arthritis; Cachexia; Diabetes Mellitus, Type 1; Graft vs Host Disease; Inflammation; Pneumonia; Polymyalgia Rheumatica; Stevens-Johnson Syndrome; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Immune System Diseases; Psoriasis; Spondylitis; Spondylitis, Ankylosing

TNF-alpha inhibitor


Small molecule Approved CANCER; OTHER ORAL Carcinoma, Merkel Cell; Central Nervous System Neoplasms; Lymphoma, Non-Hodgkin; Melanoma; Neoplasm Metastasis; Urinary Bladder Neoplasms; Anus Neoplasms; Brain Neoplasms; Breast Neoplasms, Male; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Neuroendocrine; Carcinoma, Pancreatic Ductal; Fallopian Tube Neoplasms; Glioblastoma; Glioma; Head and Neck Neoplasms; Hypopharyngeal Neoplasms; Inflammatory Breast Neoplasms; Kidney Neoplasms; Lung Neoplasms; Mesothelioma; Oropharyngeal Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Skin Neoplasms; Squamous Cell Carcinoma of Head and Neck; Thyroid Neoplasms; Triple Negative Breast Neoplasms; Uterine Cervical Neoplasms; Adenocarcinoma; Biliary Tract Neoplasms; Brain Diseases; Carcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Cholangiocarcinoma; Colorectal Neoplasms; Esophageal Neoplasms; Gallbladder Neoplasms; Hand-Foot Syndrome; Liver Neoplasms; Nasopharyngeal Neoplasms; Neuroendocrine Tumors; Pancreatic Neoplasms; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Stomach Neoplasms; Breast Neoplasms; Colonic Neoplasms; Neoplasms DNA inhibitor

Small molecule

Approved

CANCER; OTHER

ORAL

Carcinoma, Merkel Cell; Central Nervous System Neoplasms; Lymphoma, Non-Hodgkin; Melanoma; Neoplasm Metastasis; Urinary Bladder Neoplasms; Anus Neoplasms; Brain Neoplasms; Breast Neoplasms, Male; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Neuroendocrine; Carcinoma, Pancreatic Ductal; Fallopian Tube Neoplasms; Glioblastoma; Glioma; Head and Neck Neoplasms; Hypopharyngeal Neoplasms; Inflammatory Breast Neoplasms; Kidney Neoplasms; Lung Neoplasms; Mesothelioma; Oropharyngeal Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Skin Neoplasms; Squamous Cell Carcinoma of Head and Neck; Thyroid Neoplasms; Triple Negative Breast Neoplasms; Uterine Cervical Neoplasms; Adenocarcinoma; Biliary Tract Neoplasms; Brain Diseases; Carcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Cholangiocarcinoma; Colorectal Neoplasms; Esophageal Neoplasms; Gallbladder Neoplasms; Hand-Foot Syndrome; Liver Neoplasms; Nasopharyngeal Neoplasms; Neuroendocrine Tumors; Pancreatic Neoplasms; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Stomach Neoplasms; Breast Neoplasms; Colonic Neoplasms; Neoplasms

DNA inhibitor


Small molecule Approved CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Pain; Atherosclerosis; Breast Neoplasms; Coronary Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Essential Hypertension; Hypercholesterolemia; Hypertension, Renovascular; Proteinuria; Renal Artery Obstruction; Angina Pectoris; Angina, Stable; Cardiovascular Diseases; Diabetes Mellitus; Heart Failure; Hypertension; Myocardial Infarction; Stroke Type-1 angiotensin II receptor antagonist

Small molecule

Approved

CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER

ORAL

Pain; Atherosclerosis; Breast Neoplasms; Coronary Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Essential Hypertension; Hypercholesterolemia; Hypertension, Renovascular; Proteinuria; Renal Artery Obstruction; Angina Pectoris; Angina, Stable; Cardiovascular Diseases; Diabetes Mellitus; Heart Failure; Hypertension; Myocardial Infarction; Stroke

Type-1 angiotensin II receptor antagonist


Unknown Approved OTHER INTRATRACHEAL Acute Lung Injury; Bronchopulmonary Dysplasia; Respiratory Distress Syndrome; Respiratory Distress Syndrome, Newborn Surfactant agent


Small molecule Approved OTHER ORAL Unknown Unknown


Small molecule Approved IMMUNE SYSTEM; OTHER ORAL Diabetes Mellitus, Type 2; Hepatitis C; Lymphoma, Non-Hodgkin; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Acquired Immunodeficiency Syndrome; Tuberculosis; Autoimmune Diseases; HIV Infections; Infections; Virus Diseases Human immunodeficiency virus type 1 reverse transcriptase inhibitor


Small molecule Approved OTHER INTRAVESICAL Carcinoma in Situ; Urinary Bladder Neoplasms; Carcinoma; Neoplasms DNA inhibitor


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL HIV Infections; Central Nervous System Neoplasms; Head and Neck Neoplasms; Heart Failure; Leukoplakia, Oral; Non-alcoholic Fatty Liver Disease; Pituitary ACTH Hypersecretion; Sarcoma; Atherosclerosis; Insulin Resistance; Diabetes Mellitus; Diabetes Mellitus, Type 2 Peroxisome proliferator-activated receptor gamma agonist

Small molecule

Approved

OTHER

ORAL; TOPICAL

Thyroid Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Multiple Myeloma; Pituitary ACTH Hypersecretion; Alopecia Areata; Alzheimer Disease; Breast Neoplasms; Leukemia; Leukemia, Myeloid, Acute; Lung Neoplasms; Myelodysplastic-Myeloproliferative Diseases; Myelodysplastic Syndromes; Parapsoriasis; Psoriasis; Sezary Syndrome; Carcinoma, Non-Small-Cell Lung; Lymphoma; Lymphoma, Large-Cell, Anaplastic; Mycosis Fungoides; Psychotic Disorders; Schizophrenia; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous; Neoplasms

Retinoid X receptor agonist

Protein

Approved

OTHER

UNKNOWN

Kidney Neoplasms; Breast Neoplasms, Male; Carcinoma, Endometrioid; Cystadenoma, Serous; Multiple Myeloma; Fallopian Tube Neoplasms; Graft vs Host Disease; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Melanoma; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Lymphoma; Lymphoma, T-Cell, Peripheral; Lymphoma, T-Cell, Cutaneous; Neoplasms

Elongation factor 2 inhibitor


Small molecule Approved IMMUNE SYSTEM; OTHER ORAL Virus Diseases; Influenza, Human; Kidney Failure, Chronic Neuraminidase inhibitor


Small molecule Approved OTHER ORAL Metabolic Syndrome; Hyperlipoproteinemia Type I; Polycystic Ovary Syndrome; Infertility; Obesity Gastric lipase inhibitor


Small molecule Approved MUSCULOSKELETAL; OTHER; RHEUMATOLOGY ORAL Brain Neoplasms; Glioma; Alzheimer Disease; Carcinoma, Non-Small-Cell Lung; Adenoma; Colorectal Neoplasms; Joint Diseases; Osteoarthritis; Osteoarthritis, Knee; Pain; Prostatic Neoplasms, Castration-Resistant; Stomach Neoplasms; Rheumatic Diseases Cyclooxygenase-2 inhibitor


Small molecule Approved OTHER ORAL CADASIL; Fatty Liver; Osteoarthritis; Pain; Cerebral Small Vessel Diseases; Cognitive Dysfunction; Intermittent Claudication; Stroke; Atherosclerosis; Cardiovascular Diseases; Cerebral Infarction; Cerebrovascular Disorders; Coronary Disease; Peripheral Arterial Disease; Peripheral Vascular Diseases; Thrombosis Phosphodiesterase 3A inhibitor

Small molecule

Approved

CANCER; OTHER

INTRAVENOUS; ORAL

Desmoplastic Small Round Cell Tumor; Cytomegalovirus Infections; Ependymoma; Fallopian Tube Neoplasms; Meningitis, Aseptic; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Biliary Tract Neoplasms; Brain Diseases; Brain Stem Neoplasms; Breast Neoplasms; Carcinoid Tumor; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Neuroendocrine; Colorectal Neoplasms; Ganglioneuroblastoma; Gastrointestinal Stromal Tumors; Glioma; Hereditary Breast and Ovarian Cancer Syndrome; Leukemia; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma; Medulloblastoma; Myelodysplastic Syndromes; Neuroblastoma; Neuroectodermal Tumors, Primitive, Peripheral; Neurofibromatosis 1; Ovarian Neoplasms; Pancreatic Neoplasms; Pinealoma; Pituitary Neoplasms; Rectal Neoplasms; Retinoblastoma; Rhabdomyosarcoma; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Sarcoma; Skin Neoplasms; Small Cell Lung Carcinoma; Spinal Cord Neoplasms; Astrocytoma; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Choroid Plexus Neoplasms; Diffuse Intrinsic Pontine Glioma; Gliosarcoma; Melanoma; Neoplasm Metastasis; Neuroendocrine Tumors; Oligodendroglioma; Optic Nerve Glioma; Sarcoma, Ewing; Glioblastoma; Neoplasms

DNA inhibitor

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

INTRAVENOUS; ORAL

Aphasia; Canavan Disease; Essential Tremor; Stroke; Alzheimer Disease; Anemia, Sickle Cell; Bipolar Disorder; Brain Neoplasms; Cocaine-Related Disorders; Cognitive Dysfunction; Dyskinesia, Drug-Induced; Epilepsy, Absence; Epilepsy, Reflex; Glioblastoma; Glioma; Leukemia, Myeloid, Acute; Neuralgia, Postherpetic; Neuroblastoma; Obsessive-Compulsive Disorder; Opioid-Related Disorders; Parkinson Disease; Polyneuropathies; Psychotic Disorders; Restless Legs Syndrome; Stress Disorders, Post-Traumatic; Torticollis; Alcoholism; Anxiety; Dementia; Depressive Disorder; Epilepsies, Partial; Movement Disorders; Panic Disorder; Schizophrenia; Status Epilepticus; Subarachnoid Hemorrhage; Substance Withdrawal Syndrome; Epilepsy; Epilepsy, Tonic-Clonic; Seizures

Synaptic vesicle glycoprotein 2A modulator


Small molecule Approved EYE; OTHER OPHTHALMIC Chronic Pain; Conjunctivitis, Allergic; Dermatitis; Dermatitis, Atopic; Fractures, Bone; Rhinitis, Allergic, Perennial Histamine H1 receptor antagonist