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Total: 51
Small molecule
Approved
CANCER; OTHER; RESPIRATORY
ORAL
Breast Neoplasms; Colorectal Neoplasms; Diffuse Intrinsic Pontine Glioma; Glioblastoma; Kidney Diseases; Prostatic Neoplasms, Castration-Resistant; Adenocarcinoma; Bile Duct Neoplasms; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Endometrial Neoplasms; Gallbladder Neoplasms; Granuloma, Plasma Cell; Leukemia, Myeloid, Acute; Lymphoma, Large-Cell, Anaplastic; Multiple Myeloma; Neurofibromatosis 2; Stomach Neoplasms; Uveal Melanoma; Adenocarcinoma of Lung; Carcinoma; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasms
ALK tyrosine kinase receptor inhibitor
Small molecule
Approved
CANCER; OTHER; UROLOGY AND KIDNEY
ORAL
Blast Crisis; Breast Neoplasms; Carcinoma; Endometriosis; Gliosarcoma; Mesothelioma; Neoplasm Metastasis; Stomach Neoplasms; Adrenal Cortex Neoplasms; Biliary Tract Neoplasms; Carcinoid Tumor; Carcinoma, Adenoid Cystic; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colorectal Neoplasms; Endometrial Neoplasms; Gastrointestinal Stromal Tumors; Glioblastoma; Leukemia, Myeloid, Acute; Liver Neoplasms; Lung Neoplasms; Melanoma; Myelodysplastic Syndromes; Nasopharyngeal Neoplasms; Pancreatic Neoplasms; Paraganglioma; Pheochromocytoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Salivary Gland Neoplasms; Sarcoma; Sarcoma, Alveolar Soft Part; Skin Neoplasms; Solitary Fibrous Tumors; Thyroid Neoplasms; Carcinoma, Pancreatic Ductal; Kidney Neoplasms; Carcinoma, Renal Cell; Neoplasms
Vascular endothelial growth factor receptor inhibitor
Small molecule
Approved
CANCER
ORAL
Carcinoma, Renal Cell; Kidney Diseases; Liver Diseases; Pancreatic Neoplasms; Adenocarcinoma; Carcinoma; Carcinoma, Hepatocellular; Endometrial Neoplasms; Lymphoma, Mantle-Cell; Ovarian Neoplasms; Severe Acute Respiratory Syndrome; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Uterine Neoplasms; Breast Neoplasms; Neoplasms; Prostatic Neoplasms
Androgen Receptor antagonist
Small molecule
Approved
CANCER
ORAL
Primary Myelofibrosis; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Skin Neoplasms; Triple Negative Breast Neoplasms; Basal Cell Nevus Syndrome; Breast Neoplasms; Bronchiolitis Obliterans Syndrome; Carcinoma, Pancreatic Ductal; Chondrosarcoma, Clear Cell; Chondrosarcoma, Mesenchymal; Glioblastoma; Gliosarcoma; Idiopathic Pulmonary Fibrosis; Leukemia, Myeloid, Acute; Medulloblastoma; Meningioma; Multiple Myeloma; Ovarian Neoplasms; Pancreatic Neoplasms; Paraganglioma; Small Cell Lung Carcinoma; Stomach Neoplasms; Carcinoma, Basal Cell; Neoplasms
Smoothened homolog inhibitor
Antibody
Approved
CANCER
INJECTION
Burkitt Lymphoma; Colorectal Neoplasms; Hodgkin Disease; Kidney Failure, Chronic; Leukemia, Prolymphocytic; Lymphoma, T-Cell, Cutaneous; Mycosis Fungoides; Urinary Bladder Neoplasms; Carcinoma, Non-Small-Cell Lung; Glomerulonephritis; Glomerulosclerosis, Focal Segmental; Graft vs Host Disease; Leukemia; Leukemia, Hairy Cell; Leukemia, Lymphoid; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Mantle-Cell; Nephrotic Syndrome; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purpura, Thrombocytopenic, Idiopathic; Waldenstrom Macroglobulinemia; Kidney Diseases; Lupus Erythematosus, Systemic; Lupus Nephritis; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Follicular; Neoplasms
B-lymphocyte antigen CD20 binding agent
Small molecule
Approved
CANCER; HEMATOLOGY; OTHER
ORAL
Anemia, Sickle Cell; Burkitt Lymphoma; Castleman Disease; Hodgkin Disease; Immunoglobulin Light-chain Amyloidosis; Lymphoma; Lymphoma, Non-Hodgkin; Neoplasms; Pancreatic Neoplasms; Small Cell Lung Carcinoma; Waldenstrom Macroglobulinemia; Amyloidosis; Amyloidosis, Familial; Central Nervous System Neoplasms; Graft vs Host Disease; Leukemia, Plasma Cell; Lung Diseases, Interstitial; Lymphoma, Large B-Cell, Diffuse; Medulloblastoma; Myeloproliferative Disorders; Neoplasms, Plasma Cell; Plasmacytoma; Polycythemia Vera; Prostatic Neoplasms, Castration-Resistant; Pulmonary Fibrosis; Sarcoma; Sarcoma, Kaposi; Scleroderma, Systemic; Smoldering Multiple Myeloma; Telangiectasia, Hereditary Hemorrhagic; Primary Myelofibrosis; Immune System Diseases; Multiple Myeloma
CRL4(CRBN) E3 ubiquitin ligase inhibitor
Small molecule
Approved
CANCER; OTHER
ORAL
Multiple Myeloma; Carcinoma, Non-Small-Cell Lung
Epidermal growth factor receptor erbB1 inhibitor
Small molecule
Approved
CANCER; HEMATOLOGY; OTHER
ORAL
Carcinoma, Pancreatic Ductal; Leukemia, Myeloid, Acute; Multiple Myeloma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Myelofibrosis; Rhinitis, Allergic, Seasonal; Amyloidosis; Hodgkin Disease; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Waldenstrom Macroglobulinemia; Lymphoma; Lymphoma, Follicular; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Neoplasms
PI3-kinase p110-delta subunit inhibitor
Antibody
Approved
CANCER
INJECTION
Burkitt Lymphoma; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Multiple Myeloma; Hematologic Neoplasms; Leukemia, Biphenotypic, Acute; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Leukemia; Neoplasms; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma
B-lymphocyte antigen CD19 cross-linking agent
Small molecule
Approved
CANCER
ORAL
Liver Diseases; Cholangiocarcinoma; Glioblastoma; Granuloma, Plasma Cell; Lymphoma, Large-Cell, Anaplastic; Melanoma; Neuroblastoma; Thyroid Neoplasms; Sarcoma; Carcinoma, Non-Small-Cell Lung; Neoplasms
ALK tyrosine kinase receptor inhibitor
Combination
Approved
CANCER
INJECTION
Unknown
Unknown
Combination
Approved
CANCER
ORAL
Unknown
Unknown
Small molecule
Approved
CANCER
INJECTION
Unknown
Unknown
Combination
Approved
CANCER; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
ORAL
Unknown
Unknown
Small molecule
Approved
CANCER; HEMATOLOGY; OTHER
ORAL
Leukemia, Myeloid, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid
Bcr/Abl fusion protein inhibitor
Combination
Approved
CANCER; OTHER; PHARMACOLOGY
INTRAVENOUS
Unknown
Unknown