Display Options:
Total: 1496
Small molecule
Approved
OTHER
OPHTHALMIC
Conjunctivitis, Allergic; Eye Manifestations
Histamine H1 receptor antagonist
Small molecule
Approved
OTHER
TOPICAL
Lice Infestations
Nicotinic acetylcholine receptor agonist
Antibody
Approved
CANCER; OTHER
INJECTION
Hematologic Neoplasms; Leukemia; Leukemia, Myeloid, Acute; Lymphoma, T-Cell, Cutaneous; Enteropathy-Associated T-Cell Lymphoma; Graft vs Host Disease; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Mast-Cell; Lupus Erythematosus, Systemic; Lymphoma; Lymphoma, Follicular; Lymphoma, T-Cell, Peripheral; Mesothelioma; Neoplasms, Germ Cell and Embryonal; Scleroderma, Diffuse; Sezary Syndrome; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mycosis Fungoides; Hodgkin Disease; Lymphoma, Large-Cell, Anaplastic; Neoplasms
Tubulin inhibitor
Small molecule
Approved
OTHER; UROLOGY AND KIDNEY
ORAL
Kidney Diseases; Erectile Dysfunction
Phosphodiesterase 5A inhibitor
Small molecule
Approved
OTHER
INHALATION
Asthma; Bronchitis, Chronic; Emphysema; Pulmonary Disease, Chronic Obstructive
Beta-2 adrenergic receptor agonist
Small molecule
Approved
OTHER
INTRAVENOUS
Arthritis, Rheumatoid; Heart Failure
Diagnostic agent
Small molecule
Approved
CARDIOVASCULAR; HEMATOLOGY; OTHER
ORAL
Obesity, Morbid; Renal Insufficiency, Chronic; Acute Coronary Syndrome; Anemia, Sickle Cell; Aortic Valve Disease; Heart Diseases; Hemorrhage; Ischemia; Multiple Myeloma; Thromboembolism; Antiphospholipid Syndrome; Coronary Disease; Diabetes Mellitus, Type 2; Hematoma; Ischemic Stroke; Liver Cirrhosis; Myocardial Infarction; Neoplasms; Peripheral Arterial Disease; Renal Insufficiency; Rheumatic Heart Disease; Severe Acute Respiratory Syndrome; Stroke; Thrombocytopenia; Venous Thromboembolism; Atrial Fibrillation; Pulmonary Embolism; Thrombosis; Venous Thrombosis
Coagulation factor X inhibitor
Small molecule
Approved
CANCER; OTHER; RESPIRATORY
ORAL
Breast Neoplasms; Colorectal Neoplasms; Diffuse Intrinsic Pontine Glioma; Glioblastoma; Kidney Diseases; Lung Neoplasms; Prostatic Neoplasms, Castration-Resistant; Adenocarcinoma; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Endometrial Neoplasms; Granuloma, Plasma Cell; Leukemia, Myeloid, Acute; Lymphoma, Large-Cell, Anaplastic; Multiple Myeloma; Neurofibromatosis 2; Stomach Neoplasms; Adenocarcinoma of Lung; Carcinoma, Non-Small-Cell Lung; Lymphoma, Large B-Cell, Diffuse; Neoplasms
ALK tyrosine kinase receptor inhibitor
Small molecule
Approved
DIABETES DRUGS & ENDOCRINOLOGY; OTHER
ORAL
Polycystic Ovary Syndrome; Renal Insufficiency; Diabetes Mellitus, Type 1; Obesity; Diabetic Nephropathies; Heart Failure; Diabetes Mellitus; Diabetes Mellitus, Type 2
Sodium/glucose cotransporter 2 inhibitor
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
ORAL
Amyotrophic Lateral Sclerosis; Depressive Disorder; Depressive Disorder, Major; Neuralgia, Postherpetic; Epilepsy; Seizures
KCNQ (Kv7) potassium channel opener
Small molecule
Approved
CARDIOVASCULAR; OTHER
ORAL
Hypertension; Stroke
Type-1 angiotensin II receptor antagonist
Small molecule
Approved
OTHER
ORAL
Hepatitis C; Insulin Resistance; Acquired Immunodeficiency Syndrome; HIV Infections; Virus Diseases
Human immunodeficiency virus type 1 reverse transcriptase inhibitor
Small molecule
Approved
OTHER
ORAL
Central Nervous System Neoplasms; Diffuse Intrinsic Pontine Glioma; Esophageal Neoplasms; Glioblastoma; Glioma; Neuroblastoma; Rectal Neoplasms; Adenocarcinoma, Follicular; Astrocytoma; Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Carcinoma, Verrucous; Colorectal Neoplasms; Fallopian Tube Neoplasms; Gastrointestinal Stromal Tumors; Gliosarcoma; Head and Neck Neoplasms; Kidney Neoplasms; Leukemia, Myeloid, Acute; Lung Neoplasms; Mesothelioma; Multiple Myeloma; Neoplasm Metastasis; Oligodendroglioma; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Stomach Neoplasms; Ureteral Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Medullary; Neoplasms; Thyroid Neoplasms
Ephrin receptor inhibitor
Small molecule
Approved
DERMATOLOGY; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
ORAL
Kidney Diseases; Alcoholism; Diabetic Neuropathies; Migraine Disorders; Epilepsy; Neuralgia, Postherpetic; Restless Legs Syndrome
Voltage-gated calcium channel modulator
Small molecule
Approved
GASTROINTESTINAL; OTHER; UROLOGY AND KIDNEY
ORAL
Biliary Tract Neoplasms; Leukemia, Myeloid, Acute; Small Cell Lung Carcinoma; Bile Duct Neoplasms; Carcinoma; Carcinoma, Adenoid Cystic; Carcinoma, Renal Cell; Cholangiocarcinoma; Fallopian Tube Neoplasms; Glioblastoma; Hemangiosarcoma; Liposarcoma; Macular Degeneration; Melanoma; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Sarcoma; Stomach Neoplasms; Thyroid Neoplasms; Carcinoma, Hepatocellular; Colonic Neoplasms; Esophageal Neoplasms; Gastrointestinal Stromal Tumors; Colorectal Neoplasms; Neoplasms
Discoidin domain-containing receptor 2 inhibitor
Small molecule
Approved
OTHER
ORAL
Insulin Resistance; Acquired Immunodeficiency Syndrome; HIV Infections; Virus Diseases
Human immunodeficiency virus type 1 integrase inhibitor
Small molecule
Approved
OTHER
INTRAVENOUS
Prostatic Neoplasms
Diagnostic agent
Small molecule
Approved
MUSCULOSKELETAL; OTHER
ORAL
Celiac Disease; Kidney Diseases; Paraparesis, Tropical Spastic; Immune System Diseases; Multiple Sclerosis
Dihydroorotate dehydrogenase inhibitor
Protein
Approved
GASTROINTESTINAL; OTHER
ORAL
Adenoma; Constipation; Irritable Bowel Syndrome
Heat-stable enterotoxin receptor agonist
Small molecule
Approved
OTHER; UROLOGY AND KIDNEY
ORAL
Esophageal Achalasia; Kidney Diseases; Liver Diseases; Polycystic Ovary Syndrome; Heart Failure; Hypertrophy, Left Ventricular; Pain; Prediabetic State; Urinary Bladder, Neurogenic; Cystitis, Interstitial; Kidney Calculi; Polyuria; Urinary Bladder, Overactive; Urinary Incontinence; Urinary Incontinence, Urge
Beta-3 adrenergic receptor agonist
Small molecule
Approved
OTHER
ORAL
Carcinoma, Non-Small-Cell Lung; Insulin Resistance; Malaria; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Acquired Immunodeficiency Syndrome; Pneumonia, Pneumocystis; Severe Acute Respiratory Syndrome; HIV Infections; Infections
Cytochrome P450 3A inhibitor
Small molecule
Approved
CANCER; OTHER; UROLOGY AND KIDNEY
ORAL
Blast Crisis; Breast Neoplasms; Carcinoma; Endometriosis; Gliosarcoma; Mesothelioma; Stomach Neoplasms; Adrenal Cortex Neoplasms; Biliary Tract Neoplasms; Carcinoid Tumor; Carcinoma, Adenoid Cystic; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colorectal Neoplasms; Endometrial Neoplasms; Gastrointestinal Stromal Tumors; Glioblastoma; Leukemia, Myeloid, Acute; Melanoma; Myelodysplastic Syndromes; Nasopharyngeal Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Salivary Gland Neoplasms; Sarcoma; Sarcoma, Alveolar Soft Part; Skin Neoplasms; Solitary Fibrous Tumors; Thyroid Neoplasms; Carcinoma, Pancreatic Ductal; Kidney Neoplasms; Carcinoma, Renal Cell; Neoplasms
Vascular endothelial growth factor receptor inhibitor
Antibody
Approved
OTHER
IV (INFUSION)
Anthrax
Protective antigen binding agent
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS
ORAL
Alcoholism; Bipolar Disorder; Depressive Disorder, Major; Stress Disorders, Post-Traumatic; Torticollis; Amyotrophic Lateral Sclerosis; Diabetic Neuropathies; Essential Tremor; Migraine Disorders; Neuralgia; Peripheral Nervous System Diseases; Epilepsy, Tonic-Clonic; Lennox Gastaut Syndrome; Parkinson Disease; Epilepsy; Seizures
Glutamate receptor ionotropic AMPA antagonist
Small molecule
Approved
CANCER; HEMATOLOGY; OTHER
ORAL
Amyloidosis; Anemia, Sickle Cell; Castleman Disease; Hodgkin Disease; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Neoplasms; Pancreatic Neoplasms; Small Cell Lung Carcinoma; Waldenstrom Macroglobulinemia; Amyloidosis, Familial; Graft vs Host Disease; Leukemia, Plasma Cell; Lung Diseases, Interstitial; Medulloblastoma; Myeloproliferative Disorders; Plasmacytoma; Polycythemia Vera; Prostatic Neoplasms, Castration-Resistant; Pulmonary Fibrosis; Sarcoma; Sarcoma, Kaposi; Scleroderma, Systemic; Telangiectasia, Hereditary Hemorrhagic; Primary Myelofibrosis; Immune System Diseases; Multiple Myeloma
CRL4(CRBN) E3 ubiquitin ligase inhibitor
Unknown
Approved
OTHER
ORAL
Hyperphosphatemia; Renal Insufficiency, Chronic
Phosphate sequestering agent
Small molecule
Approved
CANCER; OTHER
ORAL
Multiple Myeloma; Carcinoma, Non-Small-Cell Lung
Epidermal growth factor receptor erbB1 inhibitor
Small molecule
Approved
OTHER
INTRAVENOUS
Unknown
Diagnostic agent
Small molecule
Approved
OTHER
ORAL
Depressive Disorder, Major
Norepinephrine transporter inhibitor
Small molecule
Approved
OTHER
ORAL
Hepatitis B, Chronic; Lymphoma; Infections; Severe Acute Respiratory Syndrome; Hepatitis C; Hepatitis C, Chronic; Virus Diseases
Hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor
Small molecule
Approved
IMMUNE SYSTEM; MUSCULOSKELETAL; OTHER
ORAL
Gliosarcoma; Leukemia, Lymphocytic, Chronic, B-Cell; Arthritis, Psoriatic; Arthritis, Rheumatoid; Cerebral Hemorrhage; Ischemic Stroke; Lymphoma, T-Cell, Cutaneous; Severe Acute Respiratory Syndrome; Sleep Apnea, Obstructive; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Psoriasis; Immune System Diseases; Multiple Sclerosis
Kelch-like ECH-associated protein 1 inhibitor
Small molecule
Approved
CARDIOVASCULAR; OTHER; RESPIRATORY
ORAL
HIV Infections; Anemia, Sickle Cell; Coronary Disease; Cystic Fibrosis; Raynaud Disease; Scleroderma, Localized; Scleroderma, Systemic; Ulcer; Familial Primary Pulmonary Hypertension; Hypertension; Hypertension, Pulmonary
Soluble guanylate cyclase positive allosteric modulator
Protein
Approved
DIABETES DRUGS & ENDOCRINOLOGY; OTHER
INJECTION
Diabetes Mellitus, Type 1; Polydipsia; Smoking Cessation; Diabetes Mellitus; Diabetes Mellitus, Type 2
Glucagon-like peptide 1 receptor agonist
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
ORAL
Sleep Apnea Syndromes; Tobacco Use Disorder; Alcoholism; Alzheimer Disease; Opioid-Related Disorders; Restless Legs Syndrome; Sleep Wake Disorders; Smoking Cessation; Delirium; Sleep Initiation and Maintenance Disorders
Orexin receptor antagonist
Small molecule
Approved
OTHER
INTRAVENOUS
Influenza, Human; Influenza, Human; Virus Diseases
Neuraminidase inhibitor