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Therapeutic Area
CANCER (51)
CARDIOVASCULAR (45)
DENTISTRY (2)
DERMATOLOGY (31)
DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
Level 2
Level 3
Level 4
Level 5
Level 6
Active Pharmaceutical Ingredients (APIs)
Small Molecules
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
10647
AV-380
1
Unknown
Investigational
Unknown
Unknown
Cachexia
Unknown
AV-380
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AV-412
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
AV-412
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ULILEDLIMAB
1
Antibody
Investigational
Unknown
Unknown
Neoplasms
Unknown
ULILEDLIMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CAL-263
1
Small molecule
Investigational
Unknown
Unknown
Rhinitis, Allergic, Seasonal
PI3-kinase p110-delta subunit inhibitor
CAL-263
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
RGX-104
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Liver X receptor agonist
RGX-104
×
Maximum Phase:
1
First Approval:
None
UNII:
Q26B92650V
Molecule Type:
Small molecule
Molecular Formula:
C34H33ClF3NO3
Molecular Weight:
596.09
AlogP:
8.48
PSA:
49.77
HBD:
1.0
HBA:
#RotB:
13.0
Source:
BMS-936559
1
Unknown
Investigational
Unknown
Unknown
HIV Infections
Unknown
BMS-936559
×
Maximum Phase:
1
First Approval:
None
UNII:
TLZ6R6973Z
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
DOTAMTATE
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
DOTAMTATE
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
C65H91N17O16PbS2
Molecular Weight:
1637.88
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
IBI-188
1
Unknown
Investigational
Unknown
Unknown
Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Neoplasms
Unknown
IBI-188
×
Maximum Phase:
1
First Approval:
None
UNII:
BDN84I1TFE
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
LEXANERSEN
1
Oligonucleotide
Investigational
Unknown
Unknown
Huntington Disease
Unknown
LEXANERSEN
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Oligonucleotide
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BIVATUZUMAB MERTANSINE
1
Antibody
Investigational
Unknown
Unknown
Unknown
CD44 antigen binding agent
BIVATUZUMAB MERTANSINE
×
Maximum Phase:
1
First Approval:
None
UNII:
074GT4PR9D
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GLPG0259
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
GLPG0259
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AZD-6482
1
Small molecule
Investigational
Unknown
Unknown
Unknown
PI3-kinase class I inhibitor
AZD-6482
×
Maximum Phase:
1
First Approval:
None
UNII:
78G6MP5PZ5
Molecule Type:
Small molecule
Molecular Formula:
C22H24N4O4
Molecular Weight:
408.46
AlogP:
2.71
PSA:
96.17
HBD:
2.0
HBA:
#RotB:
5.0
Source:
ELINOGREL
1
Small molecule
Investigational
Unknown
Unknown
Kidney Diseases; Myocardial Infarction
Purinergic receptor P2Y12 antagonist
ELINOGREL
×
Maximum Phase:
1
First Approval:
None
UNII:
915Y8E749J
Molecule Type:
Small molecule
Molecular Formula:
C20H15ClFN5O5S2
Molecular Weight:
523.96
AlogP:
3.09
PSA:
142.16
HBD:
4.0
HBA:
#RotB:
5.0
Source:
LIOTHYRONINE I 131
1
Small molecule
Investigational
Unknown
Unknown
Heart Defects, Congenital
Unknown
LIOTHYRONINE I 131
×
Maximum Phase:
1
First Approval:
None
UNII:
86AZ0G22V2
Molecule Type:
Small molecule
Molecular Formula:
C15H12I3NO4
Molecular Weight:
662.98
AlogP:
3.95
PSA:
92.78
HBD:
3.0
HBA:
#RotB:
5.0
Source:
IMAPRELIMAB
1
Antibody
Investigational
Unknown
Unknown
Psoriasis
Unknown
IMAPRELIMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
IYH4W60MAZ
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
LY2979165
1
Small molecule
Investigational
Unknown
Unknown
Bipolar Disorder
Metabotropic glutamate receptor 2 agonist
LY2979165
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
RGB-286638
1
Small molecule
Investigational
Unknown
Unknown
Hematologic Neoplasms
Cyclin-dependent kinase 1 inhibitor
RGB-286638
×
Maximum Phase:
1
First Approval:
None
UNII:
1GAJ98SC2X
Molecule Type:
Small molecule
Molecular Formula:
C29H35N7O4
Molecular Weight:
545.64
AlogP:
2.42
PSA:
115.06
HBD:
3.0
HBA:
#RotB:
8.0
Source:
VOFATAMAB
1
Antibody
Investigational
Unknown
Unknown
Multiple Myeloma; Neoplasms; Urinary Bladder Neoplasms
Unknown
VOFATAMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
JMH6YR91PG
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PINATUZUMAB VEDOTIN
1
Antibody
Investigational
Unknown
Unknown
Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse
CD22 binding agent
PINATUZUMAB VEDOTIN
×
Maximum Phase:
1
First Approval:
None
UNII:
6KA1906BLC
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
UC 781
1
Small molecule
Investigational
Unknown
Unknown
HIV Infections
Unknown
UC 781
×
Maximum Phase:
1
First Approval:
None
UNII:
L7K247H29H
Molecule Type:
Small molecule
Molecular Formula:
C17H18ClNO2S
Molecular Weight:
335.86
AlogP:
5.37
PSA:
34.4
HBD:
1.0
HBA:
#RotB:
5.0
Source:
OLAPTESED PEGOL
1
Unknown
Investigational
Unknown
Unknown
Glioblastoma; Pancreatic Neoplasms
Unknown
OLAPTESED PEGOL
×
Maximum Phase:
1
First Approval:
None
UNII:
MTM792B442
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
RADAVIRSEN
1
Oligonucleotide
Investigational
Unknown
Unknown
Influenza, Human
Unknown
RADAVIRSEN
×
Maximum Phase:
1
First Approval:
None
UNII:
9P30PF804H
Molecule Type:
Oligonucleotide
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CP-742,033
1
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
CP-742,033
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
IP6
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
IP6
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PA-799
1
Small molecule
Investigational
Unknown
Unknown
Neoplasms
PI3-kinase class I inhibitor
PA-799
×
Maximum Phase:
1
First Approval:
None
UNII:
JCL936W835
Molecule Type:
Small molecule
Molecular Formula:
C15H19N7O3S
Molecular Weight:
377.43
AlogP:
-0.33
PSA:
127.43
HBD:
1.0
HBA:
#RotB:
3.0
Source:
CYC-065
1
Unknown
Investigational
Unknown
Unknown
Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasms
Unknown
CYC-065
×
Maximum Phase:
1
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AZADIRACHTA INDICA
1
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
AZADIRACHTA INDICA
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TEBOTELIMAB
1
Antibody
Investigational
Unknown
Unknown
Breast Neoplasms; Carcinoma, Hepatocellular; Endometrial Neoplasms; Stomach Neoplasms; Carcinoma, Squamous Cell
Lymphocyte activation gene 3 protein inhibitor
TEBOTELIMAB
×
Maximum Phase:
1
First Approval:
None
UNII:
L62556GPXB
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AGN-201904
1
Small molecule
Investigational
Unknown
Unknown
Peptic Ulcer
Unknown
AGN-201904
×
Maximum Phase:
1
First Approval:
None
UNII:
G0835O03ZM
Molecule Type:
Small molecule
Molecular Formula:
C25H25N3O8S2
Molecular Weight:
559.62
AlogP:
3.07
PSA:
146.91
HBD:
1.0
HBA:
#RotB:
10.0
Source:
DSTP3086S
1
Antibody
Investigational
Unknown
Unknown
Unknown
Unknown
DSTP3086S
×
Maximum Phase:
1
First Approval:
None
UNII:
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
RG-7603
1
Small molecule
Investigational
Unknown
Unknown
Lymphoma, Non-Hodgkin
Serine/threonine-protein kinase mTOR inhibitor
RG-7603
×
Maximum Phase:
1
First Approval:
None
UNII:
579255I6O9
Molecule Type:
Small molecule
Molecular Formula:
C24H32N6O3
Molecular Weight:
452.56
AlogP:
2.27
PSA:
91.85
HBD:
2.0
HBA:
#RotB:
5.0
Source:
BMS-986178
1
Unknown
Investigational
Unknown
Unknown
Neoplasms
Unknown
BMS-986178
×
Maximum Phase:
1
First Approval:
None
UNII:
P9XVH8H2HF
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GSK2879552
1
Small molecule
Investigational
Unknown
Unknown
Leukemia; Myelodysplastic Syndromes; Small Cell Lung Carcinoma
Unknown
GSK2879552
×
Maximum Phase:
1
First Approval:
None
UNII:
GT77Z6Y09Z
Molecule Type:
Small molecule
Molecular Formula:
C23H28N2O2
Molecular Weight:
364.49
AlogP:
3.74
PSA:
52.57
HBD:
2.0
HBA:
#RotB:
7.0
Source:
PRI-724
1
Unknown
Investigational
Unknown
Unknown
Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Neoplasms; Colorectal Neoplasms
CBP/beta catenin inhibitor
PRI-724
×
Maximum Phase:
1
First Approval:
None
UNII:
43Y934BBZ6
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TEMANOGREL
1
Small molecule
Investigational
Unknown
Unknown
Acute Coronary Syndrome
Serotonin 2a (5-HT2a) receptor inverse agonist
TEMANOGREL
×
Maximum Phase:
1
First Approval:
None
UNII:
F42Z27575A
Molecule Type:
Small molecule
Molecular Formula:
C24H28N4O4
Molecular Weight:
436.51
AlogP:
3.06
PSA:
77.85
HBD:
1.0
HBA:
#RotB:
8.0
Source:
1
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Compound Properties
Molecular Formula
Molecular Weight
ALogP
PSA