DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 10647


Small molecule Approved OTHER INHALATION; NASAL Rhinitis, Allergic, Perennial; Asthma; Lung Diseases, Obstructive; Nasal Obstruction; Rhinitis Glucocorticoid receptor agonist


Small molecule Approved Unknown Unknown Osteomyelitis; Bacterial Infections Unknown


Small molecule Unknown Unknown Unknown Hepatitis C; Anemia, Sickle Cell; Carcinoma, Squamous Cell; Depressive Disorder; Rotator Cuff Injuries; Stress Disorders, Post-Traumatic; Toothache; Back Pain; Cocaine-Related Disorders; Depressive Disorder, Major; Heroin Dependence; HIV Infections; Intervertebral Disc Degeneration; Low Back Pain; Morphine Dependence; Neonatal Abstinence Syndrome; Neuralgia; Osteoarthritis; Substance Withdrawal Syndrome; Acute Pain; Chronic Pain; Drug Overdose; Opioid-Related Disorders; Pain; Substance-Related Disorders Kappa opioid receptor agonist

Small molecule

Unknown

Hepatitis C; Anemia, Sickle Cell; Carcinoma, Squamous Cell; Depressive Disorder; Rotator Cuff Injuries; Stress Disorders, Post-Traumatic; Toothache; Back Pain; Cocaine-Related Disorders; Depressive Disorder, Major; Heroin Dependence; HIV Infections; Intervertebral Disc Degeneration; Low Back Pain; Morphine Dependence; Neonatal Abstinence Syndrome; Neuralgia; Osteoarthritis; Substance Withdrawal Syndrome; Acute Pain; Chronic Pain; Drug Overdose; Opioid-Related Disorders; Pain; Substance-Related Disorders

Kappa opioid receptor agonist


Small molecule Approved Unknown Unknown Sleep Apnea, Obstructive; Alcoholism; Diabetic Neuropathies; Alzheimer Disease; Anxiety; Dementia; Depressive Disorder, Major; Schizophrenia; Sleep Initiation and Maintenance Disorders; Sleep Wake Disorders; Depressive Disorder Unknown


Small molecule Approved Unknown Unknown Attention Deficit Disorder with Hyperactivity; Cystic Fibrosis; Coronary Disease; Demyelinating Diseases; Hyperparathyroidism, Primary; Migraine with Aura; Multiple Sclerosis, Chronic Progressive; Optic Neuritis; Hypertension; Cardiovascular Diseases Unknown


Small molecule Approved Unknown Unknown Hypotension, Orthostatic; Orthostatic Intolerance; Depressive Disorder; Hypotension; Myocardial Infarction; Hypertension Unknown


Unknown Approved OTHER ORAL Eosinophilic Esophagitis; Duodenal Ulcer; Gastroesophageal Reflux; Peptic Ulcer Glycoproteins cross-linking agent


Small molecule Approved Unknown Unknown Osteomyelitis; Pulmonary Disease, Chronic Obstructive; Tuberculosis; Pneumonia; Cystic Fibrosis; Mycobacterium Infections; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Bacterial Infections; Eye Infections Unknown


Small molecule Approved OTHER ORAL Adrenal Hyperplasia, Congenital; Substance-Related Disorders; Anus Diseases; Epilepsies, Partial; Fissure in Ano; Proteinuria; Renal Insufficiency, Chronic; Diabetic Nephropathies; Hypertension, Pulmonary; Kidney Calculi; Myocardial Ischemia; Placenta Previa; Premature Birth; Raynaud Disease; Cardiovascular Diseases; Coronary Vasospasm; Hypertension Voltage-gated L-type calcium channel blocker

Small molecule

Approved

OTHER

ORAL

Adrenal Hyperplasia, Congenital; Substance-Related Disorders; Anus Diseases; Epilepsies, Partial; Fissure in Ano; Proteinuria; Renal Insufficiency, Chronic; Diabetic Nephropathies; Hypertension, Pulmonary; Kidney Calculi; Myocardial Ischemia; Placenta Previa; Premature Birth; Raynaud Disease; Cardiovascular Diseases; Coronary Vasospasm; Hypertension

Voltage-gated L-type calcium channel blocker


Small molecule Unknown Unknown Unknown Cardiovascular Diseases; Hodgkin Disease; Atrial Fibrillation; Heart Failure; Arrhythmias, Cardiac; Diabetes Mellitus; Hypertension Voltage-gated L-type calcium channel blocker


Small molecule Approved OTHER ORAL Multiple Sclerosis; Sunburn; Angioedema; Conjunctivitis, Allergic; Hypersensitivity; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Rhinitis, Vasomotor; Urticaria Histamine H1 receptor antagonist


Small molecule Approved OTHER INJECTION; ORAL Osteoporosis; Stress Disorders, Post-Traumatic; Atrial Fibrillation; Cerebrovascular Disorders; Essential Hypertension; Heart Diseases; Heart Failure; Hemangioma; Hypertrophy, Left Ventricular; Marfan Syndrome; Mitral Valve Stenosis; Myocardial Ischemia; Angina Pectoris; Angina, Stable; Cardiovascular Diseases; Coronary Artery Disease; Diabetes Mellitus; Hypertension; Myocardial Infarction; Stroke Beta-1 adrenergic receptor antagonist

Small molecule

Approved

OTHER

INJECTION; ORAL

Osteoporosis; Stress Disorders, Post-Traumatic; Atrial Fibrillation; Cerebrovascular Disorders; Essential Hypertension; Heart Diseases; Heart Failure; Hemangioma; Hypertrophy, Left Ventricular; Marfan Syndrome; Mitral Valve Stenosis; Myocardial Ischemia; Angina Pectoris; Angina, Stable; Cardiovascular Diseases; Coronary Artery Disease; Diabetes Mellitus; Hypertension; Myocardial Infarction; Stroke

Beta-1 adrenergic receptor antagonist


Small molecule Approved Unknown Unknown Osteomyelitis Bacterial penicillin-binding protein inhibitor


Small molecule Approved OTHER; RESPIRATORY INHALATION Depressive Disorder, Major; Diabetes Mellitus; Glycogen Storage Disease Type II; Idiopathic Pulmonary Fibrosis; Kartagener Syndrome; Lymphangioleiomyomatosis; Myasthenic Syndromes, Congenital; Bronchiolitis; Cough; Familial Primary Pulmonary Hypertension; Hypersensitivity; Memory Disorders; Pulmonary Edema; Respiratory Insufficiency; Spinal Cord Injuries; Status Asthmaticus; Dysautonomia, Familial; Heart Failure; Hypertension, Pulmonary; Lung Diseases; Organophosphate Poisoning; Rhinitis, Allergic, Seasonal; Asthma; Asthma, Exercise-Induced; Bronchial Spasm; Lung Diseases, Obstructive; Pulmonary Disease, Chronic Obstructive Beta-2 adrenergic receptor agonist

Small molecule

Approved

OTHER; RESPIRATORY

INHALATION

Depressive Disorder, Major; Diabetes Mellitus; Glycogen Storage Disease Type II; Idiopathic Pulmonary Fibrosis; Kartagener Syndrome; Lymphangioleiomyomatosis; Myasthenic Syndromes, Congenital; Bronchiolitis; Cough; Familial Primary Pulmonary Hypertension; Hypersensitivity; Memory Disorders; Pulmonary Edema; Respiratory Insufficiency; Spinal Cord Injuries; Status Asthmaticus; Dysautonomia, Familial; Heart Failure; Hypertension, Pulmonary; Lung Diseases; Organophosphate Poisoning; Rhinitis, Allergic, Seasonal; Asthma; Asthma, Exercise-Induced; Bronchial Spasm; Lung Diseases, Obstructive; Pulmonary Disease, Chronic Obstructive

Beta-2 adrenergic receptor agonist


Small molecule Approved Unknown Unknown Osteomyelitis; Appendicitis; Peritonitis; Sepsis; Bacterial Infections Unknown


Small molecule Approved IMMUNE SYSTEM; OTHER ORAL; TOPICAL Glioblastoma; Insulin Resistance; Alzheimer Disease; Asthma; Diabetes Mellitus, Type 2; Erectile Dysfunction; Essential Hypertension; Gastroparesis; Hepatitis C; Immune System Diseases; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, Non-Hodgkin; Melanoma; Multiple Sclerosis; Nausea; Neuroblastoma; Osteoporosis; Premature Birth; Pulmonary Disease, Chronic Obstructive; Breast Neoplasms; Burns; Hypogonadism; Neoplasms; Prostatic Neoplasms; Psoriasis; Acne Vulgaris; Candidiasis, Vulvovaginal; Dermatitis; Prostatic Neoplasms, Castration-Resistant; Respiratory Distress Syndrome; Vaginosis, Bacterial; Adrenal Gland Diseases; Blastomycosis; Dermatitis, Seborrheic; Onychomycosis; Tinea; Tinea Pedis Cytochrome P450 51 inhibitor

Small molecule

Approved

IMMUNE SYSTEM; OTHER

ORAL; TOPICAL

Glioblastoma; Insulin Resistance; Alzheimer Disease; Asthma; Diabetes Mellitus, Type 2; Erectile Dysfunction; Essential Hypertension; Gastroparesis; Hepatitis C; Immune System Diseases; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, Non-Hodgkin; Melanoma; Multiple Sclerosis; Nausea; Neuroblastoma; Osteoporosis; Premature Birth; Pulmonary Disease, Chronic Obstructive; Breast Neoplasms; Burns; Hypogonadism; Neoplasms; Prostatic Neoplasms; Psoriasis; Acne Vulgaris; Candidiasis, Vulvovaginal; Dermatitis; Prostatic Neoplasms, Castration-Resistant; Respiratory Distress Syndrome; Vaginosis, Bacterial; Adrenal Gland Diseases; Blastomycosis; Dermatitis, Seborrheic; Onychomycosis; Tinea; Tinea Pedis

Cytochrome P450 51 inhibitor


Small molecule Approved OTHER ORAL Asthma; Diabetes Mellitus, Type 1; Migraine Disorders; Phobia, Social; Substance-Related Disorders; Epilepsy; Stress Disorders, Post-Traumatic; Dementia; Depressive Disorder; Schizophrenia; Anxiety; Anxiety Disorders; Panic Disorder GABA-A receptor; anion channel positive allosteric modulator


Small molecule Approved OTHER ORAL Alzheimer Disease; Anemia; Diabetes Mellitus, Type 2; HIV Infections; Hypertriglyceridemia; Neoplasms; Alcoholism; Myocardial Ischemia; Smoking Cessation; Tobacco Use Disorder; Abdominal Pain; Cardiovascular Diseases; Coronary Disease Peroxisome proliferator-activated receptor alpha agonist


Small molecule Approved CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Diabetes Mellitus, Type 2; Glioblastoma; Hypertension, Pulmonary; Neoplasms; Primary Myelofibrosis; Heart Diseases; Pneumonia; Severe Acute Respiratory Syndrome; Cardiovascular Diseases; Collagen Diseases; Diabetic Nephropathies; Diabetic Retinopathy; Heart Failure; Hypertension; Myocardial Infarction; Renal Insufficiency; Ventricular Dysfunction, Left Angiotensin-converting enzyme inhibitor

Small molecule

Approved

CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER

ORAL

Diabetes Mellitus, Type 2; Glioblastoma; Hypertension, Pulmonary; Neoplasms; Primary Myelofibrosis; Heart Diseases; Pneumonia; Severe Acute Respiratory Syndrome; Cardiovascular Diseases; Collagen Diseases; Diabetic Nephropathies; Diabetic Retinopathy; Heart Failure; Hypertension; Myocardial Infarction; Renal Insufficiency; Ventricular Dysfunction, Left

Angiotensin-converting enzyme inhibitor


Small molecule Approved Unknown Unknown Osteomyelitis; Otitis Media; Communicable Diseases; Graft vs Host Disease; Abscess; Cholecystitis, Acute; Diabetic Foot; Enterobacteriaceae Infections; Hematologic Neoplasms; Infections; Pancreatic Neoplasms; Pneumonia; Pneumonia, Bacterial; Pseudomonas Infections; Pyelonephritis; Sepsis; Shock, Septic; Urinary Tract Infections; Bacterial Infections Unknown

Small molecule

Approved

Unknown

Osteomyelitis; Otitis Media; Communicable Diseases; Graft vs Host Disease; Abscess; Cholecystitis, Acute; Diabetic Foot; Enterobacteriaceae Infections; Hematologic Neoplasms; Infections; Pancreatic Neoplasms; Pneumonia; Pneumonia, Bacterial; Pseudomonas Infections; Pyelonephritis; Sepsis; Shock, Septic; Urinary Tract Infections; Bacterial Infections

Unknown


Small molecule Approved Unknown Unknown Anemia; HIV Infections; Malaria; Malaria, Falciparum; Malaria, Vivax; Pneumonia, Pneumocystis; Pregnancy; Premature Birth Dihydropteroate synthetase inhibitor


Small molecule Approved OTHER ORAL Anxiety GABA-A receptor; anion channel positive allosteric modulator


Small molecule Approved OTHER ORAL Lung Diseases, Obstructive Adenosine receptor antagonist


Small molecule Approved CARDIOVASCULAR; GASTROINTESTINAL; OTHER INJECTION; INTRA-ANAL; SUBLINGUAL; TRANSDERMAL Colorectal Neoplasms; Hypotension; Peripheral Arterial Disease; Hypertension, Pulmonary; Infections; Inflammation; Phlebitis; Rectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Diabetic Neuropathies; Erectile Dysfunction; Hot Flashes; Lung Neoplasms; Shock; Tendinopathy; Arthritis, Rheumatoid; Bone Diseases, Metabolic; Muscle Cramp; Myocardial Ischemia; Osteoporosis; Raynaud Disease; Reperfusion Injury; Scleroderma, Localized; Stroke; Wounds and Injuries; Angina Pectoris; Angina, Stable; Cardiovascular Diseases; Coronary Artery Disease; Coronary Disease; Heart Failure; Hemorrhoids; Hypertension; Myocardial Infarction; Pain Soluble guanylate cyclase activator

Small molecule

Approved

CARDIOVASCULAR; GASTROINTESTINAL; OTHER

INJECTION; INTRA-ANAL; SUBLINGUAL; TRANSDERMAL

Colorectal Neoplasms; Hypotension; Peripheral Arterial Disease; Hypertension, Pulmonary; Infections; Inflammation; Phlebitis; Rectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Diabetic Neuropathies; Erectile Dysfunction; Hot Flashes; Lung Neoplasms; Shock; Tendinopathy; Arthritis, Rheumatoid; Bone Diseases, Metabolic; Muscle Cramp; Myocardial Ischemia; Osteoporosis; Raynaud Disease; Reperfusion Injury; Scleroderma, Localized; Stroke; Wounds and Injuries; Angina Pectoris; Angina, Stable; Cardiovascular Diseases; Coronary Artery Disease; Coronary Disease; Heart Failure; Hemorrhoids; Hypertension; Myocardial Infarction; Pain

Soluble guanylate cyclase activator


Small molecule Approved OTHER ORAL Anxiety; Dementia; Depressive Disorder; Pulmonary Disease, Chronic Obstructive; Schizophrenia; Sleep Initiation and Maintenance Disorders GABA-A receptor; anion channel positive allosteric modulator

Small molecule

Approved

CARDIOVASCULAR; OTHER; UROLOGY AND KIDNEY

INJECTION; URETHRAL

Arteriosclerosis Obliterans; Optic Neuropathy, Ischemic; Peripheral Arterial Disease; Peripheral Vascular Diseases; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Sexual Dysfunction, Physiological; Heart Failure; Macular Degeneration; Prostatic Neoplasms, Castration-Resistant; Cardiovascular Diseases; Ductus Arteriosus, Patent; Erectile Dysfunction

Prostanoid EP1 receptor agonist


Small molecule Approved Unknown Unknown Hypoxia-Ischemia, Brain; Asthma; Pre-Eclampsia; Purpura, Thrombotic Thrombocytopenic Unknown


Small molecule Approved Unknown Unknown Helminthiasis Unknown


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved OTHER ORAL Arrhythmias, Cardiac Sodium channel alpha subunit blocker


Small molecule Approved OTHER INJECTION Unknown Androgen Receptor agonist


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved Unknown Unknown Hypersensitivity Unknown


Small molecule Approved OTHER ORAL Ovarian Cysts; Endometrial Hyperplasia; Abortion, Habitual; Infertility; Infertility, Female; Menopause; Pregnancy; Premature Birth Progesterone receptor agonist


Small molecule Approved OTHER ORAL Epilepsy GABA-A receptor; anion channel positive allosteric modulator