DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 10647


Small molecule Approved OTHER INHALATION; NASAL Rhinitis, Allergic, Perennial; Asthma; Lung Diseases, Obstructive; Nasal Obstruction; Rhinitis Glucocorticoid receptor agonist


Small molecule Approved Unknown Unknown Hypoxia-Ischemia, Brain; Asthma; Pre-Eclampsia; Purpura, Thrombotic Thrombocytopenic Unknown


Small molecule Approved Unknown Unknown Sleep Apnea, Obstructive; Alcoholism; Diabetic Neuropathies; Alzheimer Disease; Anxiety; Dementia; Depressive Disorder, Major; Schizophrenia; Sleep Initiation and Maintenance Disorders; Sleep Wake Disorders; Depressive Disorder Unknown


Small molecule Unknown Unknown Unknown Hepatitis C; Anemia, Sickle Cell; Carcinoma, Squamous Cell; Depressive Disorder; Rotator Cuff Injuries; Stress Disorders, Post-Traumatic; Toothache; Back Pain; Cocaine-Related Disorders; Depressive Disorder, Major; Heroin Dependence; HIV Infections; Intervertebral Disc Degeneration; Low Back Pain; Morphine Dependence; Neonatal Abstinence Syndrome; Neuralgia; Osteoarthritis; Substance Withdrawal Syndrome; Acute Pain; Chronic Pain; Drug Overdose; Opioid-Related Disorders; Pain; Substance-Related Disorders Kappa opioid receptor agonist

Small molecule

Unknown

Hepatitis C; Anemia, Sickle Cell; Carcinoma, Squamous Cell; Depressive Disorder; Rotator Cuff Injuries; Stress Disorders, Post-Traumatic; Toothache; Back Pain; Cocaine-Related Disorders; Depressive Disorder, Major; Heroin Dependence; HIV Infections; Intervertebral Disc Degeneration; Low Back Pain; Morphine Dependence; Neonatal Abstinence Syndrome; Neuralgia; Osteoarthritis; Substance Withdrawal Syndrome; Acute Pain; Chronic Pain; Drug Overdose; Opioid-Related Disorders; Pain; Substance-Related Disorders

Kappa opioid receptor agonist


Small molecule Approved Unknown Unknown Attention Deficit Disorder with Hyperactivity; Cystic Fibrosis; Coronary Disease; Demyelinating Diseases; Hyperparathyroidism, Primary; Migraine with Aura; Multiple Sclerosis, Chronic Progressive; Optic Neuritis; Hypertension; Cardiovascular Diseases Unknown


Small molecule Approved Unknown Unknown Hypotension, Orthostatic; Orthostatic Intolerance; Depressive Disorder; Hypotension; Myocardial Infarction; Hypertension Unknown


Small molecule Approved OTHER ORAL Multiple Sclerosis; Sunburn; Angioedema; Conjunctivitis, Allergic; Hypersensitivity; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Rhinitis, Vasomotor; Urticaria Histamine H1 receptor antagonist


Unknown Approved OTHER ORAL Eosinophilic Esophagitis; Duodenal Ulcer; Gastroesophageal Reflux; Peptic Ulcer Glycoproteins cross-linking agent


Small molecule Approved Unknown Unknown Osteomyelitis; Pulmonary Disease, Chronic Obstructive; Tuberculosis; Pneumonia; Cystic Fibrosis; Mycobacterium Infections; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Bacterial Infections; Eye Infections Unknown


Small molecule Unknown Unknown Unknown Cardiovascular Diseases; Hodgkin Disease; Atrial Fibrillation; Heart Failure; Arrhythmias, Cardiac; Diabetes Mellitus; Hypertension Voltage-gated L-type calcium channel blocker


Small molecule Approved OTHER ORAL Adrenal Hyperplasia, Congenital; Substance-Related Disorders; Anus Diseases; Epilepsies, Partial; Fissure in Ano; Proteinuria; Renal Insufficiency, Chronic; Diabetic Nephropathies; Hypertension, Pulmonary; Kidney Calculi; Myocardial Ischemia; Placenta Previa; Premature Birth; Raynaud Disease; Cardiovascular Diseases; Coronary Vasospasm; Hypertension Voltage-gated L-type calcium channel blocker

Small molecule

Approved

OTHER

ORAL

Adrenal Hyperplasia, Congenital; Substance-Related Disorders; Anus Diseases; Epilepsies, Partial; Fissure in Ano; Proteinuria; Renal Insufficiency, Chronic; Diabetic Nephropathies; Hypertension, Pulmonary; Kidney Calculi; Myocardial Ischemia; Placenta Previa; Premature Birth; Raynaud Disease; Cardiovascular Diseases; Coronary Vasospasm; Hypertension

Voltage-gated L-type calcium channel blocker


Small molecule Approved CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Diabetes Mellitus, Type 2; Glioblastoma; Hypertension, Pulmonary; Neoplasms; Primary Myelofibrosis; Heart Diseases; Pneumonia; Severe Acute Respiratory Syndrome; Cardiovascular Diseases; Collagen Diseases; Diabetic Nephropathies; Diabetic Retinopathy; Heart Failure; Hypertension; Myocardial Infarction; Renal Insufficiency; Ventricular Dysfunction, Left Angiotensin-converting enzyme inhibitor

Small molecule

Approved

CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER

ORAL

Diabetes Mellitus, Type 2; Glioblastoma; Hypertension, Pulmonary; Neoplasms; Primary Myelofibrosis; Heart Diseases; Pneumonia; Severe Acute Respiratory Syndrome; Cardiovascular Diseases; Collagen Diseases; Diabetic Nephropathies; Diabetic Retinopathy; Heart Failure; Hypertension; Myocardial Infarction; Renal Insufficiency; Ventricular Dysfunction, Left

Angiotensin-converting enzyme inhibitor


Small molecule Approved Unknown Unknown Osteomyelitis; Appendicitis; Peritonitis; Sepsis; Bacterial Infections Unknown


Small molecule Approved IMMUNE SYSTEM; OTHER ORAL; TOPICAL Glioblastoma; Insulin Resistance; Alzheimer Disease; Asthma; Diabetes Mellitus, Type 2; Erectile Dysfunction; Essential Hypertension; Gastroparesis; Hepatitis C; Immune System Diseases; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, Non-Hodgkin; Melanoma; Multiple Sclerosis; Nausea; Neuroblastoma; Osteoporosis; Premature Birth; Pulmonary Disease, Chronic Obstructive; Breast Neoplasms; Burns; Hypogonadism; Neoplasms; Prostatic Neoplasms; Psoriasis; Acne Vulgaris; Candidiasis, Vulvovaginal; Dermatitis; Prostatic Neoplasms, Castration-Resistant; Respiratory Distress Syndrome; Vaginosis, Bacterial; Adrenal Gland Diseases; Blastomycosis; Dermatitis, Seborrheic; Onychomycosis; Tinea; Tinea Pedis Cytochrome P450 51 inhibitor

Small molecule

Approved

IMMUNE SYSTEM; OTHER

ORAL; TOPICAL

Glioblastoma; Insulin Resistance; Alzheimer Disease; Asthma; Diabetes Mellitus, Type 2; Erectile Dysfunction; Essential Hypertension; Gastroparesis; Hepatitis C; Immune System Diseases; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, Non-Hodgkin; Melanoma; Multiple Sclerosis; Nausea; Neuroblastoma; Osteoporosis; Premature Birth; Pulmonary Disease, Chronic Obstructive; Breast Neoplasms; Burns; Hypogonadism; Neoplasms; Prostatic Neoplasms; Psoriasis; Acne Vulgaris; Candidiasis, Vulvovaginal; Dermatitis; Prostatic Neoplasms, Castration-Resistant; Respiratory Distress Syndrome; Vaginosis, Bacterial; Adrenal Gland Diseases; Blastomycosis; Dermatitis, Seborrheic; Onychomycosis; Tinea; Tinea Pedis

Cytochrome P450 51 inhibitor


Small molecule Approved OTHER ORAL Alzheimer Disease; Anemia; Diabetes Mellitus, Type 2; HIV Infections; Hypertriglyceridemia; Neoplasms; Alcoholism; Myocardial Ischemia; Smoking Cessation; Tobacco Use Disorder; Abdominal Pain; Cardiovascular Diseases; Coronary Disease Peroxisome proliferator-activated receptor alpha agonist


Small molecule Approved Unknown Unknown Osteomyelitis Bacterial penicillin-binding protein inhibitor


Small molecule Approved OTHER; RESPIRATORY INHALATION Depressive Disorder, Major; Diabetes Mellitus; Glycogen Storage Disease Type II; Idiopathic Pulmonary Fibrosis; Kartagener Syndrome; Lymphangioleiomyomatosis; Myasthenic Syndromes, Congenital; Bronchiolitis; Cough; Familial Primary Pulmonary Hypertension; Hypersensitivity; Memory Disorders; Pulmonary Edema; Respiratory Insufficiency; Spinal Cord Injuries; Status Asthmaticus; Dysautonomia, Familial; Heart Failure; Hypertension, Pulmonary; Lung Diseases; Organophosphate Poisoning; Rhinitis, Allergic, Seasonal; Asthma; Asthma, Exercise-Induced; Bronchial Spasm; Lung Diseases, Obstructive; Pulmonary Disease, Chronic Obstructive Beta-2 adrenergic receptor agonist

Small molecule

Approved

OTHER; RESPIRATORY

INHALATION

Depressive Disorder, Major; Diabetes Mellitus; Glycogen Storage Disease Type II; Idiopathic Pulmonary Fibrosis; Kartagener Syndrome; Lymphangioleiomyomatosis; Myasthenic Syndromes, Congenital; Bronchiolitis; Cough; Familial Primary Pulmonary Hypertension; Hypersensitivity; Memory Disorders; Pulmonary Edema; Respiratory Insufficiency; Spinal Cord Injuries; Status Asthmaticus; Dysautonomia, Familial; Heart Failure; Hypertension, Pulmonary; Lung Diseases; Organophosphate Poisoning; Rhinitis, Allergic, Seasonal; Asthma; Asthma, Exercise-Induced; Bronchial Spasm; Lung Diseases, Obstructive; Pulmonary Disease, Chronic Obstructive

Beta-2 adrenergic receptor agonist


Small molecule Approved OTHER ORAL Anxiety; Dementia; Depressive Disorder; Pulmonary Disease, Chronic Obstructive; Schizophrenia; Sleep Initiation and Maintenance Disorders GABA-A receptor; anion channel positive allosteric modulator


Small molecule Approved OTHER ORAL Asthma; Diabetes Mellitus, Type 1; Migraine Disorders; Phobia, Social; Substance-Related Disorders; Epilepsy; Stress Disorders, Post-Traumatic; Dementia; Depressive Disorder; Schizophrenia; Anxiety; Anxiety Disorders; Panic Disorder GABA-A receptor; anion channel positive allosteric modulator


Small molecule Approved Unknown Unknown Osteomyelitis; Otitis Media; Communicable Diseases; Graft vs Host Disease; Abscess; Cholecystitis, Acute; Diabetic Foot; Enterobacteriaceae Infections; Hematologic Neoplasms; Infections; Pancreatic Neoplasms; Pneumonia; Pneumonia, Bacterial; Pseudomonas Infections; Pyelonephritis; Sepsis; Shock, Septic; Urinary Tract Infections; Bacterial Infections Unknown

Small molecule

Approved

Unknown

Osteomyelitis; Otitis Media; Communicable Diseases; Graft vs Host Disease; Abscess; Cholecystitis, Acute; Diabetic Foot; Enterobacteriaceae Infections; Hematologic Neoplasms; Infections; Pancreatic Neoplasms; Pneumonia; Pneumonia, Bacterial; Pseudomonas Infections; Pyelonephritis; Sepsis; Shock, Septic; Urinary Tract Infections; Bacterial Infections

Unknown


Small molecule Approved OTHER ORAL Anxiety GABA-A receptor; anion channel positive allosteric modulator


Small molecule Approved OTHER ORAL Lung Diseases, Obstructive Adenosine receptor antagonist


Small molecule Approved OTHER INJECTION; ORAL Osteoporosis; Stress Disorders, Post-Traumatic; Atrial Fibrillation; Cerebrovascular Disorders; Essential Hypertension; Heart Diseases; Heart Failure; Hemangioma; Hypertrophy, Left Ventricular; Marfan Syndrome; Mitral Valve Stenosis; Myocardial Ischemia; Angina Pectoris; Angina, Stable; Cardiovascular Diseases; Coronary Artery Disease; Diabetes Mellitus; Hypertension; Myocardial Infarction; Stroke Beta-1 adrenergic receptor antagonist

Small molecule

Approved

OTHER

INJECTION; ORAL

Osteoporosis; Stress Disorders, Post-Traumatic; Atrial Fibrillation; Cerebrovascular Disorders; Essential Hypertension; Heart Diseases; Heart Failure; Hemangioma; Hypertrophy, Left Ventricular; Marfan Syndrome; Mitral Valve Stenosis; Myocardial Ischemia; Angina Pectoris; Angina, Stable; Cardiovascular Diseases; Coronary Artery Disease; Diabetes Mellitus; Hypertension; Myocardial Infarction; Stroke

Beta-1 adrenergic receptor antagonist


Small molecule Approved Unknown Unknown Anemia; HIV Infections; Malaria; Malaria, Falciparum; Malaria, Vivax; Pneumonia, Pneumocystis; Pregnancy; Premature Birth Dihydropteroate synthetase inhibitor


Small molecule Approved CARDIOVASCULAR; OTHER; UROLOGY AND KIDNEY INJECTION; URETHRAL Arteriosclerosis Obliterans; Optic Neuropathy, Ischemic; Peripheral Arterial Disease; Peripheral Vascular Diseases; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Sexual Dysfunction, Physiological; Heart Failure; Macular Degeneration; Prostatic Neoplasms, Castration-Resistant; Cardiovascular Diseases; Ductus Arteriosus, Patent; Erectile Dysfunction Prostanoid EP1 receptor agonist

Small molecule

Approved

CARDIOVASCULAR; OTHER; UROLOGY AND KIDNEY

INJECTION; URETHRAL

Arteriosclerosis Obliterans; Optic Neuropathy, Ischemic; Peripheral Arterial Disease; Peripheral Vascular Diseases; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Sexual Dysfunction, Physiological; Heart Failure; Macular Degeneration; Prostatic Neoplasms, Castration-Resistant; Cardiovascular Diseases; Ductus Arteriosus, Patent; Erectile Dysfunction

Prostanoid EP1 receptor agonist

Small molecule

Approved

CARDIOVASCULAR; GASTROINTESTINAL; OTHER

INJECTION; INTRA-ANAL; SUBLINGUAL; TRANSDERMAL

Colorectal Neoplasms; Hypotension; Peripheral Arterial Disease; Hypertension, Pulmonary; Infections; Inflammation; Phlebitis; Rectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Diabetic Neuropathies; Erectile Dysfunction; Hot Flashes; Lung Neoplasms; Shock; Tendinopathy; Arthritis, Rheumatoid; Bone Diseases, Metabolic; Muscle Cramp; Myocardial Ischemia; Osteoporosis; Raynaud Disease; Reperfusion Injury; Scleroderma, Localized; Stroke; Wounds and Injuries; Angina Pectoris; Angina, Stable; Cardiovascular Diseases; Coronary Artery Disease; Coronary Disease; Heart Failure; Hemorrhoids; Hypertension; Myocardial Infarction; Pain

Soluble guanylate cyclase activator


Small molecule Approved Unknown Unknown Osteomyelitis; Bacterial Infections Unknown


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved OTHER ORAL Arrhythmias, Cardiac Sodium channel alpha subunit blocker


Small molecule Approved OTHER INJECTION Unknown Muscle-type nicotinic acetylcholine receptor antagonist


Small molecule Approved Unknown Unknown Helminthiasis Unknown


Small molecule Approved OTHER TOPICAL Lice Infestations; Ectoparasitic Infestations Acetylcholinesterase inhibitor


Small molecule Approved Unknown Unknown Hypersensitivity Unknown


Small molecule Approved OTHER INJECTION Unknown Androgen Receptor agonist


Small molecule Approved OTHER ORAL Ovarian Cysts; Endometrial Hyperplasia; Abortion, Habitual; Infertility; Infertility, Female; Menopause; Pregnancy; Premature Birth Progesterone receptor agonist