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Total: 1496
Small molecule
Approved
OTHER
ORAL
Unknown
Bacterial 70S ribosome inhibitor
Small molecule
Approved
OTHER
ORAL
Psoriasis; Sinusitis; Diabetic Retinopathy; Lichen Planus, Oral; Macular Degeneration; Nasal Polyps; Optic Neuropathy, Ischemic; Rotator Cuff Injuries; Abdominal Pain; Acneiform Eruptions; Alopecia Areata; Dermatitis, Atopic; Melanoma; Melanosis; Osteoarthritis, Knee; Shoulder Pain; Vascular Diseases; Vitiligo; Wet Macular Degeneration; Keloid; Macular Edema; Osteoarthritis; Pain; Pancreatitis, Chronic; Pulmonary Disease, Chronic Obstructive; Radiculopathy; Retinal Vein Occlusion; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Eye Diseases; Hemorrhoids; Lung Diseases, Obstructive; Nasal Obstruction; Skin Diseases
Glucocorticoid receptor agonist
Small molecule
Approved
OTHER
ORAL
Unknown
Muscarinic acetylcholine receptor M1 antagonist
Small molecule
Approved
OTHER
OPHTHALMIC
Glaucoma
Acetylcholinesterase inhibitor
Small molecule
Approved
OTHER
IM-IV; INJECTION; ORAL
Liver Cirrhosis; Pain
Carbonic anhydrase I inhibitor
Small molecule
Approved
OTHER
ORAL
Unknown
Vitamin K-dependent gamma-carboxylase inhibitor
Small molecule
Approved
OTHER
ORAL
Melanoma; Venous Thrombosis; Thrombosis
Vitamin k epoxide reductase complex subunit 1 isoform 1 inhibitor
Small molecule
Approved
OTHER
RECTAL
Delirium; Glioblastoma; Neonatal Abstinence Syndrome; Severe Acute Respiratory Syndrome; Conduct Disorder; Porphyrias; Postoperative Nausea and Vomiting; Psychotic Disorders; Schizophrenia
D2-like dopamine receptor antagonist
Small molecule
Approved
OTHER
ORAL
Epilepsy; Seizures
Sodium channel alpha subunit blocker
Small molecule
Approved
OTHER
ORAL
Friedreich Ataxia; Atherosclerosis; Chemical and Drug Induced Liver Injury; Cognitive Dysfunction; DiGeorge Syndrome; Frontotemporal Dementia; Gangliosidoses; Gaucher Disease; Hearing Loss, Noise-Induced; Immune System Diseases; Mucocutaneous Lymph Node Syndrome; Muscular Diseases; Myasthenia Gravis; Optic Nerve Diseases; Ovarian Hyperstimulation Syndrome; Parkinson Disease; Stiff-Person Syndrome; Adenomatous Polyposis Coli; Amyotrophic Lateral Sclerosis; Anemia, Aplastic; Appendicitis; Breast Neoplasms; Burkitt Lymphoma; Carcinoma, Non-Small-Cell Lung; Carpal Tunnel Syndrome; Coronavirus Infections; Death, Sudden, Cardiac; Fallopian Tube Neoplasms; Fanconi Anemia; Fasciitis, Plantar; Graves Ophthalmopathy; Hantavirus Infections; Hepatitis, Alcoholic; Hyperlipoproteinemia Type I; Immunoblastic Lymphadenopathy; Immunoglobulin G4-Related Disease; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, AIDS-Related; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Lymphoproliferative Disorders; Melanoma; Meniere Disease; Myelodysplastic-Myeloproliferative Diseases; Myelodysplastic Syndromes; Myeloproliferative Disorders; Nasal Polyps; Neoplasms; Neuromyelitis Optica; Ovarian Neoplasms; Pain; Prostatic Neoplasms; Purpura, Schoenlein-Henoch; Radiculopathy; Sinusitis; Spasms, Infantile; Spondylarthropathies; Spondylitis, Ankylosing; Abdominal Pain; Aging; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Bell Palsy; Bronchopulmonary Dysplasia; Deglutition Disorders; Dermatomyositis; Edema; Glomerulonephritis, IGA; Glomerulonephritis, Membranous; Graft vs Host Disease; Granulomatosis with Polyangiitis; Heart Arrest; Heart Diseases; Hematologic Neoplasms; Hematoma, Subdural, Intracranial; Hodgkin Disease; Ischemic Stroke; Kidney Diseases; Leukemia; Leukemia, Biphenotypic, Acute; Lupus Erythematosus, Systemic; Lupus Nephritis; Lymphohistiocytosis, Hemophagocytic; Lymphoma; Microscopic Polyangiitis; Multiple Myeloma; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Optic Neuritis; Optic Neuropathy, Ischemic; Pneumonia, Pneumocystis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Pulpitis; Purpura, Thrombocytopenic, Idiopathic; Renal Insufficiency, Chronic; Respiratory Distress Syndrome; Respiratory Tract Diseases; Scleroderma, Systemic; Severe Acute Respiratory Syndrome; Specific Language Disorder; Spinal Cord Injuries; Thrombocytopenia; Urinary Tract Infections; Vestibular Neuronitis; Acne Vulgaris; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Bursitis; Colitis, Ulcerative; Crohn Disease; Dermatitis, Atopic; Inflammation; Multiple Sclerosis; Osteoarthritis; Pneumonia; Tenosynovitis
Glucocorticoid receptor agonist
Small molecule
Approved
OTHER
ORAL
Psychotic Disorders
Dopamine D2 receptor antagonist
Small molecule
Approved
OTHER
ORAL
Epilepsy; Seizures
Voltage-gated T-type calcium channel blocker
Small molecule
Approved
OTHER
ORAL
Hypertension
Synaptic vesicular amine transporter inhibitor
Protein
Approved
OTHER
FOR RX COMPOUNDING; INJECTION
Eczema; Hordeolum; Bacteremia; Infections; Inflammation
Cell outer membrane inhibitor
Small molecule
Approved
OTHER
ORAL
Carcinoma, Pancreatic Ductal; Lymphoma, Mantle-Cell; Glomerulonephritis, Membranous; Glomerulosclerosis, Focal Segmental; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Stomach Neoplasms; Hodgkin Disease; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma
DNA inhibitor
Small molecule
Approved
OTHER
ORAL
Unknown
Bacterial penicillin-binding protein inhibitor
Small molecule
Approved
OTHER
ORAL
Osteomyelitis; Pneumonia; Arthritis; Bacteremia; Bacterial Infections; Endocarditis, Bacterial; Infections; Meningitis; Scarlet Fever
Bacterial penicillin-binding protein inhibitor
Small molecule
Approved
OTHER
ORAL
Unknown
Intermediate conductance calcium-activated potassium channel protein 4 opener
Small molecule
Approved
OTHER
ORAL
Cough
Slowly adapting pulmonary stretch receptor inhibitor
Small molecule
Approved
OTHER
ORAL
Hypokalemic Periodic Paralysis; Myotonic Disorders; Paralysis, Hyperkalemic Periodic; Glaucoma
Carbonic anhydrase II inhibitor
Small molecule
Approved
OTHER
ORAL
Diabetes Mellitus; Diabetes Mellitus, Type 2
Sulfonylurea receptor 1, Kir6.2 blocker
Protein
Approved
OTHER
OTIC
Unknown
Unknown
Small molecule
Approved
EYE; OTHER
INTRAOCULAR; INTRAVITREAL; OPHTHALMIC; ORAL; TOPICAL
Hypertension; Radius Fractures; Tooth Diseases; Adrenal Insufficiency; Aortic Coarctation; Brain Edema; Esophageal Neoplasms; Graves Disease; Head and Neck Neoplasms; Heart Failure; Lacrimal Apparatus Diseases; Lung Neoplasms; Lymphoma, T-Cell, Cutaneous; Meningeal Carcinomatosis; Osteoarthritis, Knee; Rheumatic Diseases; Rotator Cuff Injuries; Scleritis; Vitiligo; Appendicitis; Blast Crisis; Brain Neoplasms; Breast Carcinoma In Situ; Breast Neoplasms; Burkitt Lymphoma; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Castleman Disease; Cholangiocarcinoma; Dry Eye Syndromes; Dyspnea; Endocrine Gland Neoplasms; Endometrial Neoplasms; Fasciitis, Plantar; Glomerulonephritis; Gout; Hearing Loss; Hearing Loss, Sensorineural; Hematologic Neoplasms; Hematoma, Subdural, Intracranial; Hemorrhage; Histiocytosis, Langerhans-Cell; Histiocytosis, Sinus; Intestinal Obstruction; Intracranial Hypertension; Kidney Diseases; Leptospirosis; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Plasma Cell; Leukemia, T-Cell; Lichen Planus; Liposarcoma, Myxoid; Liver Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell, Peripheral; Macular Degeneration; Melanoma; Meningitis; Meningitis, Cryptococcal; Mesothelioma; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neck Pain; Neoplasm Metastasis; Nervous System Diseases; Pancreatic Neoplasms; POEMS Syndrome; Premature Birth; Pulmonary Fibrosis; Purpura, Schoenlein-Henoch; Purpura, Thrombotic Thrombocytopenic; Radiculopathy; Rectal Neoplasms; Red-Cell Aplasia, Pure; Respiratory Tract Diseases; Retinal Vein Occlusion; Sciatica; Stomach Neoplasms; Tonsillitis; Toxoplasmosis, Cerebral; Tuberculosis; Urinary Bladder Neoplasms; Uveitis, Intermediate; Wet Macular Degeneration; Xerostomia; Amyloidosis; Amyloidosis, Familial; Anemia; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Anemia, Sickle Cell; Atrioventricular Block; Back Pain; Blepharitis; Bronchiolitis; Bronchopulmonary Dysplasia; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Cataract; Chronic Pain; Colorectal Neoplasms; Conjunctivitis, Viral; Cysticercosis; Deafness; Deglutition Disorders; Dermatitis; Encephalitis, Herpes Simplex; Fatigue; Genital Neoplasms, Female; Glaucoma; Glomerulosclerosis, Focal Segmental; Graft vs Host Disease; Granuloma, Lethal Midline; Headache; HELLP Syndrome; Hernias, Diaphragmatic, Congenital; Hodgkin Disease; Hypersensitivity; Knee Injuries; Leiomyoma; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Leukemia, Promyelocytic, Acute; Lichen Planus, Oral; Liver Cirrhosis; Lymphohistiocytosis, Hemophagocytic; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Malaria; Mastoiditis; Meniere Disease; Migraine Disorders; Multiple Myeloma; Myelodysplastic Syndromes; Nausea; Nephrosis; Neuralgia; Otitis Externa; Otitis Media; Ovarian Hyperstimulation Syndrome; Ovarian Neoplasms; Pain; Pelvic Organ Prolapse; Plasmacytoma; Pneumonia, Viral; Postoperative Nausea and Vomiting; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Renal Insufficiency, Chronic; Respiratory Distress Syndrome; Rhinitis, Allergic, Perennial; Sarcoma; Severe Acute Respiratory Syndrome; Small Cell Lung Carcinoma; Smoldering Multiple Myeloma; Specific Language Disorder; Strabismus; Urinary Tract Infections; Uveitis, Anterior; Vaginosis, Bacterial; Vitreoretinopathy, Proliferative; Vomiting; Waldenstrom Macroglobulinemia; Wounds and Injuries; Acne Vulgaris; Addison Disease; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Anemia, Aplastic; Anemia, Hemolytic; Arthritis, Gouty; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Bursitis; Chorioretinitis; Choroiditis; Colitis, Ulcerative; Conjunctivitis, Allergic; Crohn Disease; Dermatitis, Atopic; Dermatitis, Contact; Dermatitis, Exfoliative; Dermatitis Herpetiformis; Dermatitis, Seborrheic; Diabetic Retinopathy; Erythema Multiforme; Eye Diseases; Hemorrhoids; Herpes Zoster Ophthalmicus; Hypercalcemia; Infections; Inflammation; Iridocyclitis; Iritis; Keratitis; Leukemia; Lupus Erythematosus, Systemic; Lymphoma; Macular Edema; Multiple Sclerosis; Mycosis Fungoides; Myocarditis; Nasal Obstruction; Neoplasms; Nephrotic Syndrome; Ophthalmia, Sympathetic; Optic Neuritis; Osteoarthritis; Pemphigus; Peptic Ulcer; Pneumonia; Psoriasis; Pulmonary Eosinophilia; Purpura, Thrombocytopenic, Idiopathic; Rhinitis, Allergic, Seasonal; Sarcoidosis; Serum Sickness; Spondylitis, Ankylosing; Stevens-Johnson Syndrome; Synovitis; Tennis Elbow; Tenosynovitis; Thrombocytopenia; Thyroiditis, Subacute; Trichinellosis; Tuberculosis, Meningeal; Tuberculosis, Pulmonary; Uveitis, Posterior
Glucocorticoid receptor agonist
Small molecule
Approved
OTHER
ORAL
Unknown
DNA inhibitor
Small molecule
Approved
OTHER
ORAL
Atherosclerosis; Coronary Disease; Diabetes Mellitus, Type 2; Heart Diseases; Hypercholesterolemia; Cardiovascular Diseases; Edema; Glomerulonephritis; Heart Failure; Hypertension; Kidney Failure, Chronic; Nephrotic Syndrome; Toxemia
Thiazide-sensitive sodium-chloride cotransporter inhibitor
Small molecule
Approved
OTHER
INHALATION
Unknown
GABA-A receptor; anion channel positive allosteric modulator
Small molecule
Approved
OTHER
INJECTION; ORAL; SUBCUTANEOUS
Pregnancy; Alzheimer Disease; Endometrial Hyperplasia; HIV Infections; Pain; Primary Ovarian Insufficiency; Sleep Apnea Syndromes; Coronary Disease; Diabetes Mellitus; Endometrial Neoplasms; Heart Diseases; Hot Flashes; Hypercholesterolemia; Hypertension; Infertility; Kidney Neoplasms; Lupus Erythematosus, Systemic; Menopause; Menorrhagia; Myocardial Ischemia; Osteoporosis; Prostatic Neoplasms; Thrombosis; Turner Syndrome; Carcinoma, Renal Cell; Endometriosis; Hemorrhage; Hyperplasia; Neoplasms; Uterine Hemorrhage
Progesterone receptor agonist
Small molecule
Approved
OTHER
INJECTION; INTRAVENOUS
Neoplasms, Neuroepithelial; Anemia; Chordoma; Crohn Disease; Fallopian Tube Neoplasms; Kidney Neoplasms; Liver Neoplasms; Neoplasms, Germ Cell and Embryonal; Ovarian Neoplasms; Peritoneal Neoplasms; Severe Combined Immunodeficiency; Wiskott-Aldrich Syndrome; Anemia, Sickle Cell; Breast Neoplasms, Male; Ganglioneuroblastoma; Glioma; Hematologic Diseases; Hematologic Neoplasms; Inflammatory Breast Neoplasms; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Osteosarcoma; Primary Myelofibrosis; Sarcoma; Brain Neoplasms; Breast Neoplasms; Central Nervous System Neoplasms; Graft vs Host Disease; Leukemia; Medulloblastoma; Neuroblastoma; Neuroectodermal Tumors, Primitive; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retinoblastoma; Adenocarcinoma; Carcinoma; Hodgkin Disease; Neoplasms
DNA inhibitor
Small molecule
Approved
OTHER
OPHTHALMIC
Unknown
Acetylcholinesterase inhibitor
Small molecule
Approved
DIABETES DRUGS & ENDOCRINOLOGY; OTHER
ORAL
Metabolic Syndrome; Diabetes Mellitus; Lecithin Cholesterol Acyltransferase Deficiency; Kidney Diseases; Atherosclerosis; Coronary Disease; Death, Sudden, Cardiac; Diabetes Mellitus, Type 2; Essential Hypertension; Hypercholesterolemia; Kidney Calculi; Pre-Eclampsia; Angina Pectoris; Cardiovascular Diseases; Edema; Glomerulonephritis; Heart Failure; Hypertension; Kidney Failure, Chronic; Liver Cirrhosis; Myocardial Infarction; Nephrotic Syndrome; Renal Insufficiency, Chronic; Toxemia
Thiazide-sensitive sodium-chloride cotransporter inhibitor
Unknown
Approved
OTHER
OPHTHALMIC
Autistic Disorder
Polypeptides proteolytic enzyme
Small molecule
Approved
OTHER
ORAL
Cardiovascular Diseases
Thiazide-sensitive sodium-chloride cotransporter inhibitor
Small molecule
Approved
OTHER
ORAL
Gout
Solute carrier family 22 member 12 inhibitor
Small molecule
Approved
OTHER
INJECTION; INTERSTITIAL; INTRAVENOUS
Inflammatory Breast Neoplasms; Arthritis, Rheumatoid; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Head and Neck Neoplasms; Lung Neoplasms; Lymphedema; Melanoma; Breast Neoplasms; Periodontitis; Endometrial Neoplasms; Hirschsprung Disease; Periodontal Diseases; Retinal Perforations; Stomach Neoplasms
Diagnostic agent
Small molecule
Approved
OTHER
ORAL
Cardiovascular Diseases; Hypertension
Thiazide-sensitive sodium-chloride cotransporter inhibitor