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Therapeutic Area
CANCER (51)
CARDIOVASCULAR (45)
DENTISTRY (2)
DERMATOLOGY (31)
DIABETES DRUGS & ENDOCRINOLOGY (61)
EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
HEMATOLOGY (23)
MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
Level 2
Level 3
Level 4
Level 5
Level 6
Active Pharmaceutical Ingredients (APIs)
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
10647
IMPLITAPIDE
2
Small molecule
Investigational
Unknown
Unknown
Hyperlipoproteinemia Type II; Hypertriglyceridemia
Microsomal triglyceride transfer protein inhibitor
IMPLITAPIDE
×
Maximum Phase:
2
First Approval:
None
UNII:
Q70OH404HR
Molecule Type:
Small molecule
Molecular Formula:
C35H37N3O2
Molecular Weight:
531.7
AlogP:
6.98
PSA:
67.15
HBD:
2.0
HBA:
#RotB:
8.0
Source:
SOLCITINIB
2
Small molecule
Investigational
Unknown
Unknown
Colitis, Ulcerative; Lupus Erythematosus, Systemic; Psoriasis
Tyrosine-protein kinase JAK1 inhibitor
SOLCITINIB
×
Maximum Phase:
2
First Approval:
None
UNII:
3V7GQ1260K
Molecule Type:
Small molecule
Molecular Formula:
C22H23N5O2
Molecular Weight:
389.46
AlogP:
3.23
PSA:
79.6
HBD:
1.0
HBA:
#RotB:
4.0
Source:
O-(2-FLUOROETHYL)-L-TYROSINE F-18
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
O-(2-FLUOROETHYL)-L-TYROSINE F-18
×
Maximum Phase:
2
First Approval:
None
UNII:
1326R5J1IA
Molecule Type:
Small molecule
Molecular Formula:
C11H14FNO3
Molecular Weight:
226.24
AlogP:
0.99
PSA:
72.55
HBD:
2.0
HBA:
#RotB:
6.0
Source:
SAMALIZUMAB
2
Antibody
Investigational
Unknown
Unknown
Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Multiple Myeloma; Neoplasms
OX-2 membrane glycoprotein inhibitor
SAMALIZUMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
64EUX713G6
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GRC-6211
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Vanilloid receptor antagonist
GRC-6211
×
Maximum Phase:
2
First Approval:
None
UNII:
4S841S9BO9
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
MACOZINONE
2
Small molecule
Investigational
Unknown
Unknown
Tuberculosis
Unknown
MACOZINONE
×
Maximum Phase:
2
First Approval:
None
UNII:
A3M1353L40
Molecule Type:
Small molecule
Molecular Formula:
C20H23F3N4O3S
Molecular Weight:
456.49
AlogP:
4.29
PSA:
79.58
HBD:
0.0
HBA:
#RotB:
4.0
Source:
MENAQUINONE 7
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
MENAQUINONE 7
×
Maximum Phase:
2
First Approval:
None
UNII:
8427BML8NY
Molecule Type:
Small molecule
Molecular Formula:
C46H64O2
Molecular Weight:
649.02
AlogP:
14.1
PSA:
34.14
HBD:
0.0
HBA:
#RotB:
20.0
Source:
FAZA
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
FAZA
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
OLINVACIMAB
2
Antibody
Investigational
Unknown
Unknown
Breast Neoplasms; Glioblastoma
Vascular endothelial growth factor receptor 2 inhibitor
OLINVACIMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
VFH55IZ5VI
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BOSWELLIC ACID
2
Small molecule
Investigational
Unknown
Unknown
Multiple Sclerosis, Relapsing-Remitting
Unknown
BOSWELLIC ACID
×
Maximum Phase:
2
First Approval:
None
UNII:
B252M1YO2V
Molecule Type:
Small molecule
Molecular Formula:
C30H48O3
Molecular Weight:
456.71
AlogP:
7.09
PSA:
57.53
HBD:
2.0
HBA:
#RotB:
1.0
Source:
SER-100
2
Protein
Investigational
Unknown
Unknown
Hypertension
Unknown
SER-100
×
Maximum Phase:
2
First Approval:
None
UNII:
VJ98TJ922K
Molecule Type:
Protein
Molecular Formula:
C85H141N27O15
Molecular Weight:
1781.24
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
PACTIMIBE
2
Small molecule
Investigational
Unknown
Unknown
Atherosclerosis; Coronary Disease
Unknown
PACTIMIBE
×
Maximum Phase:
2
First Approval:
None
UNII:
D874R9PZ9T
Molecule Type:
Small molecule
Molecular Formula:
C25H40N2O3
Molecular Weight:
416.61
AlogP:
5.64
PSA:
69.64
HBD:
2.0
HBA:
#RotB:
10.0
Source:
ZIMLOVISERTIB
2
Small molecule
Investigational
Unknown
Unknown
Arthritis, Rheumatoid; Hidradenitis Suppurativa; Severe Acute Respiratory Syndrome
Interleukin-1 receptor-associated kinase 4 inhibitor
ZIMLOVISERTIB
×
Maximum Phase:
2
First Approval:
None
UNII:
S3F315JJXI
Molecule Type:
Small molecule
Molecular Formula:
C18H20FN3O4
Molecular Weight:
361.37
AlogP:
1.58
PSA:
103.54
HBD:
2.0
HBA:
#RotB:
6.0
Source:
ISIS-463588
2
Unknown
Investigational
Unknown
Unknown
Obesity
Unknown
ISIS-463588
×
Maximum Phase:
2
First Approval:
None
UNII:
YJ4APB5MQC
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
SSR125543
2
Small molecule
Investigational
Unknown
Unknown
Depressive Disorder; Adrenal Hyperplasia, Congenital
Corticotropin releasing factor receptor 1 antagonist
SSR125543
×
Maximum Phase:
2
First Approval:
None
UNII:
MFT24BX55I
Molecule Type:
Small molecule
Molecular Formula:
C27H28ClFN2OS
Molecular Weight:
483.05
AlogP:
7.52
PSA:
25.36
HBD:
0.0
HBA:
#RotB:
8.0
Source:
STI-3031
2
Unknown
Investigational
Unknown
Unknown
Granuloma, Lethal Midline; Neoplasms
Unknown
STI-3031
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
FIRSOCOSTAT
2
Small molecule
Investigational
Unknown
Unknown
Non-alcoholic Fatty Liver Disease
Acetyl-CoA carboxylase negative allosteric modulator
FIRSOCOSTAT
×
Maximum Phase:
2
First Approval:
None
UNII:
XE10NJQ95M
Molecule Type:
Small molecule
Molecular Formula:
C28H31N3O8S
Molecular Weight:
569.64
AlogP:
3.95
PSA:
135.02
HBD:
1.0
HBA:
#RotB:
9.0
Source:
DERSALAZINE SODIUM
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
DERSALAZINE SODIUM
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PLECONARIL
2
Small molecule
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 1; Sepsis; Virus Diseases
VP1 capsid protein disrupting agent
PLECONARIL
×
Maximum Phase:
2
First Approval:
None
UNII:
9H4570Q89D
Molecule Type:
Small molecule
Molecular Formula:
C18H18F3N3O3
Molecular Weight:
381.35
AlogP:
4.68
PSA:
74.18
HBD:
0.0
HBA:
#RotB:
6.0
Source:
PEMRAMETOSTAT
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Breast Neoplasms
Unknown
PEMRAMETOSTAT
×
Maximum Phase:
2
First Approval:
None
UNII:
VXT8SZ6875
Molecule Type:
Small molecule
Molecular Formula:
C24H32N6O3
Molecular Weight:
452.56
AlogP:
1.05
PSA:
110.69
HBD:
3.0
HBA:
#RotB:
7.0
Source:
ZSTK-474
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms
PI3-kinase class I inhibitor
ZSTK-474
×
Maximum Phase:
2
First Approval:
None
UNII:
K0068GK39A
Molecule Type:
Small molecule
Molecular Formula:
C23H17NOS
Molecular Weight:
355.46
AlogP:
6.25
PSA:
32.59
HBD:
1.0
HBA:
#RotB:
1.0
Source:
RG-4733
2
Small molecule
Investigational
Unknown
Unknown
Astrocytoma; Breast Neoplasms; Neoplasms; Oligodendroglioma; Breast Neoplasms, Male; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Colonic Neoplasms; Colorectal Neoplasms; Fallopian Tube Neoplasms; Gliosarcoma; Melanoma; Multiple Myeloma; Ovarian Neoplasms; Prostatic Neoplasms; Rectal Neoplasms; Triple Negative Breast Neoplasms
Gamma-secretase inhibitor
RG-4733
×
Maximum Phase:
2
First Approval:
None
UNII:
KK8645V7LE
Molecule Type:
Small molecule
Molecular Formula:
C22H20F5N3O3
Molecular Weight:
469.41
AlogP:
3.8
PSA:
87.3
HBD:
3.0
HBA:
#RotB:
5.0
Source:
MODITHROMYCIN
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
MODITHROMYCIN
×
Maximum Phase:
2
First Approval:
None
UNII:
9MAY4E090U
Molecule Type:
Small molecule
Molecular Formula:
C43H64N6O11
Molecular Weight:
841.02
AlogP:
3.7
PSA:
205.72
HBD:
2.0
HBA:
#RotB:
8.0
Source:
PLATELETS
2
Unknown
Investigational
Unknown
Unknown
Osteoarthritis; Brain Injuries; Dupuytren Contracture; Stroke; Thrombocytopenia; Hemorrhage; Wounds and Injuries
Unknown
PLATELETS
×
Maximum Phase:
2
First Approval:
None
UNII:
V82T6JEZ99
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PEGADRICASE
2
Enzyme
Investigational
Unknown
Unknown
Gout
Uric acid oxidative enzyme
PEGADRICASE
×
Maximum Phase:
2
First Approval:
None
UNII:
50XB37EKN8
Molecule Type:
Enzyme
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
OLORINAB
2
Small molecule
Investigational
Unknown
Unknown
Abdominal Pain; Crohn Disease; Irritable Bowel Syndrome
Cannabinoid CB2 receptor agonist
OLORINAB
×
Maximum Phase:
2
First Approval:
None
UNII:
581F7DFA9B
Molecule Type:
Small molecule
Molecular Formula:
C18H23N5O3
Molecular Weight:
357.41
AlogP:
0.7
PSA:
106.98
HBD:
2.0
HBA:
#RotB:
4.0
Source:
PPS
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
PPS
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
EFINOPEGDUTIDE
2
Protein
Investigational
Unknown
Unknown
Diabetes Mellitus, Type 2; Renal Insufficiency, Chronic; Non-alcoholic Fatty Liver Disease; Obesity
Glucagon-like peptide 1 receptor agonist
EFINOPEGDUTIDE
×
Maximum Phase:
2
First Approval:
None
UNII:
DR6P1M58PO
Molecule Type:
Protein
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GEDIVUMAB
2
Antibody
Investigational
Unknown
Unknown
Influenza, Human
Hemagglutinin inhibitor
GEDIVUMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
6IRE1TI49I
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ATSM COPPER (II)
2
Small molecule
Investigational
Unknown
Unknown
Parkinson Disease; Amyotrophic Lateral Sclerosis
Unknown
ATSM COPPER (II)
×
Maximum Phase:
2
First Approval:
None
UNII:
0YDK1H9L3A
Molecule Type:
Small molecule
Molecular Formula:
C8H14CuN6S2
Molecular Weight:
321.92
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
LTX-109
2
Small molecule
Investigational
Unknown
Unknown
Hidradenitis Suppurativa; Staphylococcal Infections; Impetigo; Severe Acute Respiratory Syndrome
Cell membrane disrupting agent
LTX-109
×
Maximum Phase:
2
First Approval:
None
UNII:
HO813QDF65
Molecule Type:
Small molecule
Molecular Formula:
C43H69N11O3
Molecular Weight:
788.1
AlogP:
3.79
PSA:
252.91
HBD:
11.0
HBA:
#RotB:
18.0
Source:
DELPARANTAG
2
Small molecule
Investigational
Unknown
Unknown
Coronary Disease
Unknown
DELPARANTAG
×
Maximum Phase:
2
First Approval:
None
UNII:
FSY46235ZO
Molecule Type:
Small molecule
Molecular Formula:
C56H79N13O12
Molecular Weight:
1126.33
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
COLENEURAMIDE
2
Small molecule
Investigational
Unknown
Unknown
Diabetic Neuropathies
Unknown
COLENEURAMIDE
×
Maximum Phase:
2
First Approval:
None
UNII:
G2D52T65LR
Molecule Type:
Small molecule
Molecular Formula:
C39H68N2O8
Molecular Weight:
692.98
AlogP:
4.3
PSA:
157.58
HBD:
6.0
HBA:
#RotB:
12.0
Source:
CASTOR OIL
2
Small molecule
Investigational
Unknown
Unknown
Premature Birth; Constipation
Unknown
CASTOR OIL
×
Maximum Phase:
2
First Approval:
None
UNII:
D5340Y2I9G
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
HISTIDINE
2
Small molecule
Investigational
Unknown
Unknown
Irritable Bowel Syndrome; Hernias, Diaphragmatic, Congenital; Multiple Sclerosis
Unknown
HISTIDINE
×
Maximum Phase:
2
First Approval:
None
UNII:
4QD397987E
Molecule Type:
Small molecule
Molecular Formula:
C6H9N3O2
Molecular Weight:
155.16
AlogP:
-0.64
PSA:
92.0
HBD:
3.0
HBA:
#RotB:
3.0
Source:
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Molecular Formula
Molecular Weight
ALogP
PSA