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EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
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MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
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OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
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Level 3
Level 4
Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
10647
EMACTUZUMAB
2
Antibody
Investigational
Unknown
Unknown
Lymphoma, Non-Hodgkin; Neoplasms
Macrophage colony stimulating factor receptor inhibitor
EMACTUZUMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
6FY6EI1X8R
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
FAPI GA-68
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
FAPI GA-68
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C40H53GaN10O10
Molecular Weight:
903.65
AlogP:
None
PSA:
None
HBD:
None
HBA:
#RotB:
None
Source:
OBATOCLAX
2
Small molecule
Investigational
Unknown
Unknown
Small Cell Lung Carcinoma; Leukemia, Myeloid, Acute
Unknown
OBATOCLAX
×
Maximum Phase:
2
First Approval:
None
UNII:
QN4128B52A
Molecule Type:
Small molecule
Molecular Formula:
C20H19N3O
Molecular Weight:
317.39
AlogP:
4.49
PSA:
53.17
HBD:
2.0
HBA:
#RotB:
3.0
Source:
INDOXIMOD
2
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung; Ependymoma; Gliosarcoma; Leukemia, Myeloid, Acute; Medulloblastoma; Breast Neoplasms; Melanoma; Prostatic Neoplasms
Unknown
INDOXIMOD
×
Maximum Phase:
2
First Approval:
None
UNII:
TX5CYN1KMZ
Molecule Type:
Small molecule
Molecular Formula:
C12H14N2O2
Molecular Weight:
218.26
AlogP:
1.13
PSA:
68.25
HBD:
2.0
HBA:
#RotB:
3.0
Source:
VEBICORVIR
2
Small molecule
Investigational
Unknown
Unknown
Hepatitis B, Chronic
Unknown
VEBICORVIR
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C19H12F3N3O4S2
Molecular Weight:
467.45
AlogP:
3.49
PSA:
105.23
HBD:
2.0
HBA:
#RotB:
3.0
Source:
IRX-4204
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Parkinson Disease; Carcinoma, Non-Small-Cell Lung; Prostatic Neoplasms, Castration-Resistant
Retinoid X receptor agonist
IRX-4204
×
Maximum Phase:
2
First Approval:
None
UNII:
877M97Z38Y
Molecule Type:
Small molecule
Molecular Formula:
C24H32O2
Molecular Weight:
352.52
AlogP:
5.9
PSA:
37.3
HBD:
1.0
HBA:
#RotB:
4.0
Source:
ETO
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
ETO
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CORT118335
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
CORT118335
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
VESATOLIMOD
2
Small molecule
Investigational
Unknown
Unknown
Hepatitis C; HIV Infections; Acquired Immunodeficiency Syndrome; Hepatitis B, Chronic
Toll-like receptor 7 activator
VESATOLIMOD
×
Maximum Phase:
2
First Approval:
None
UNII:
O8M467C50G
Molecule Type:
Small molecule
Molecular Formula:
C22H30N6O2
Molecular Weight:
410.52
AlogP:
2.79
PSA:
96.61
HBD:
2.0
HBA:
#RotB:
8.0
Source:
DAPANSUTRILE
2
Small molecule
Investigational
Unknown
Unknown
Heart Failure, Systolic; Melanoma; Schnitzler Syndrome; Severe Acute Respiratory Syndrome
NACHT, LRR and PYD domains-containing protein 3 inhibitor
DAPANSUTRILE
×
Maximum Phase:
2
First Approval:
None
UNII:
2Z03364G96
Molecule Type:
Small molecule
Molecular Formula:
C4H7NO2S
Molecular Weight:
133.17
AlogP:
-0.06
PSA:
57.93
HBD:
0.0
HBA:
#RotB:
2.0
Source:
SERIBANTUMAB
2
Antibody
Investigational
Unknown
Unknown
Breast Neoplasms; Pancreatic Neoplasms
Receptor tyrosine-protein kinase erbB-3 inhibitor
SERIBANTUMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
1N3L70MDFX
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ADL-5747
2
Small molecule
Investigational
Unknown
Unknown
Neuralgia, Postherpetic; Osteoarthritis, Knee
Delta opioid receptor agonist
ADL-5747
×
Maximum Phase:
2
First Approval:
None
UNII:
BRJ718SA03
Molecule Type:
Small molecule
Molecular Formula:
C24H29ClN2O3
Molecular Weight:
428.96
AlogP:
3.82
PSA:
61.8
HBD:
2.0
HBA:
#RotB:
4.0
Source:
IRX-2
2
Unknown
Investigational
Unknown
Unknown
Carcinoma, Hepatocellular; Breast Neoplasms; Carcinoma, Squamous Cell; Squamous Cell Carcinoma of Head and Neck; Squamous Intraepithelial Lesions
Unknown
IRX-2
×
Maximum Phase:
2
First Approval:
None
UNII:
ZDR4QSJ43F
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
P144
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
P144
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BIROPEPIMUT-S
2
Unknown
Investigational
Unknown
Unknown
Squamous Cell Carcinoma of Head and Neck
Melanoma-associated antigen 3 vaccine antigen
BIROPEPIMUT-S
×
Maximum Phase:
2
First Approval:
None
UNII:
6XJF4EZC5Z
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
TC-6987
2
Small molecule
Investigational
Unknown
Unknown
Asthma; Diabetes Mellitus, Type 2
Neuronal acetylcholine receptor protein alpha-7 subunit agonist
TC-6987
×
Maximum Phase:
2
First Approval:
None
UNII:
Q2U4R164OG
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
CB-103
2
Small molecule
Investigational
Unknown
Unknown
Breast Neoplasms
Unknown
CB-103
×
Maximum Phase:
2
First Approval:
None
UNII:
Q5BB91JL0V
Molecule Type:
Small molecule
Molecular Formula:
C15H18N2O
Molecular Weight:
242.32
AlogP:
3.75
PSA:
48.14
HBD:
1.0
HBA:
#RotB:
2.0
Source:
VALZIFLOCEPT
2
Protein
Investigational
Unknown
Unknown
Glomerulonephritis, IGA
Unknown
VALZIFLOCEPT
×
Maximum Phase:
2
First Approval:
None
UNII:
EA2075XV4Y
Molecule Type:
Protein
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PRESATOVIR
2
Small molecule
Investigational
Unknown
Unknown
Respiratory Syncytial Virus Infections
Fusion glycoprotein F0 inhibitor
PRESATOVIR
×
Maximum Phase:
2
First Approval:
None
UNII:
9628AJ27JA
Molecule Type:
Small molecule
Molecular Formula:
C24H30ClN7O3S
Molecular Weight:
532.07
AlogP:
2.97
PSA:
125.93
HBD:
2.0
HBA:
#RotB:
5.0
Source:
BIFUNCTIONAL EPOXIDE HYDROLASE 2
2
Enzyme
Investigational
Unknown
Unknown
Heart Failure
Unknown
BIFUNCTIONAL EPOXIDE HYDROLASE 2
×
Maximum Phase:
2
First Approval:
None
UNII:
JEH09DQZ6V
Molecule Type:
Enzyme
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BMS-777607
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms
Hepatocyte growth factor receptor inhibitor
BMS-777607
×
Maximum Phase:
2
First Approval:
None
UNII:
A3MMS6HDO1
Molecule Type:
Small molecule
Molecular Formula:
C25H19ClF2N4O4
Molecular Weight:
512.9
AlogP:
5.19
PSA:
108.47
HBD:
2.0
HBA:
#RotB:
7.0
Source:
TBA-7371
2
Small molecule
Investigational
Unknown
Unknown
Tuberculosis; Tuberculosis, Pulmonary
FAD-dependent decaprenylphosphoryl-beta-D-ribofuranose 2-oxidase inhibitor
TBA-7371
×
Maximum Phase:
2
First Approval:
None
UNII:
R3T98GBE3C
Molecule Type:
Small molecule
Molecular Formula:
C18H21N5O3
Molecular Weight:
355.4
AlogP:
1.22
PSA:
102.16
HBD:
2.0
HBA:
#RotB:
6.0
Source:
BEETROOT JUICE
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
BEETROOT JUICE
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
APL-501
2
Unknown
Investigational
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung; Neoplasms; Lymphoma, Follicular; Lymphoma, T-Cell, Peripheral; Sarcoma, Alveolar Soft Part; Uterine Cervical Neoplasms
Programmed cell death protein 1 inhibitor
APL-501
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
LY-2940094
2
Small molecule
Investigational
Unknown
Unknown
Depressive Disorder, Major; Parkinson Disease
Nociceptin receptor antagonist
LY-2940094
×
Maximum Phase:
2
First Approval:
None
UNII:
4I67US2V8Q
Molecule Type:
Small molecule
Molecular Formula:
C22H23ClF2N4O2S
Molecular Weight:
480.97
AlogP:
4.4
PSA:
63.41
HBD:
1.0
HBA:
#RotB:
4.0
Source:
POVIDONE
2
Small molecule
Investigational
Unknown
Unknown
Thymoma; Blepharitis
Unknown
POVIDONE
×
Maximum Phase:
2
First Approval:
None
UNII:
FZ989GH94E
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ACLARUBICIN
2
Small molecule
Investigational
Unknown
Unknown
Myelodysplastic Syndromes; Leukemia, Myeloid, Acute; Neoplasms
Unknown
ACLARUBICIN
×
Maximum Phase:
2
First Approval:
None
UNII:
74KXF8I502
Molecule Type:
Small molecule
Molecular Formula:
C42H53NO15
Molecular Weight:
811.88
AlogP:
3.16
PSA:
217.05
HBD:
4.0
HBA:
#RotB:
9.0
Source:
VODOBATINIB
2
Small molecule
Investigational
Unknown
Unknown
Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Dementia; Parkinson Disease
Bcr/Abl fusion protein inhibitor
VODOBATINIB
×
Maximum Phase:
2
First Approval:
None
UNII:
N8Q12KU2SW
Molecule Type:
Small molecule
Molecular Formula:
C27H20ClN3O2
Molecular Weight:
453.93
AlogP:
4.98
PSA:
71.09
HBD:
2.0
HBA:
#RotB:
2.0
Source:
ANATIBANT
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Bradykinin B2 receptor antagonist
ANATIBANT
×
Maximum Phase:
2
First Approval:
None
UNII:
CLO4JRD21F
Molecule Type:
Small molecule
Molecular Formula:
C34H36Cl2N6O5S
Molecular Weight:
711.67
AlogP:
5.11
PSA:
167.57
HBD:
4.0
HBA:
#RotB:
12.0
Source:
AMUVATINIB
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Small Cell Lung Carcinoma
Hepatocyte growth factor receptor inhibitor
AMUVATINIB
×
Maximum Phase:
2
First Approval:
None
UNII:
SO9S6QZB4R
Molecule Type:
Small molecule
Molecular Formula:
C23H21N5O3S
Molecular Weight:
447.52
AlogP:
3.3
PSA:
75.89
HBD:
1.0
HBA:
#RotB:
3.0
Source:
MGAWN1
2
Antibody
Investigational
Unknown
Unknown
West Nile Fever
E protein inhibitor
MGAWN1
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
NAVAFENTEROL
2
Small molecule
Investigational
Unknown
Unknown
Pulmonary Disease, Chronic Obstructive
Beta-2 adrenergic receptor agonist
NAVAFENTEROL
×
Maximum Phase:
2
First Approval:
None
UNII:
U29GY32XJ4
Molecule Type:
Small molecule
Molecular Formula:
C38H42N6O6S2
Molecular Weight:
742.92
AlogP:
5.04
PSA:
165.83
HBD:
5.0
HBA:
#RotB:
14.0
Source:
INVAC-1, A DOUBLE STRANDED DNA PLASMID VACCINE CONSTRUCT ENCODING UBIQUITIN-HUMAN TELOMERASE REVERSE TRANSCRIPTASE (HTERT) FUSION PROTEIN
2
Enzyme
Investigational
Unknown
Unknown
Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell
Unknown
INVAC-1, A DOUBLE STRANDED DNA PLASMID VACCINE CONSTRUCT ENCODING UBIQUITIN-HUMAN TELOMERASE REVERSE TRANSCRIPTASE (HTERT) FUSION PROTEIN
×
Maximum Phase:
2
First Approval:
None
UNII:
S8GQZ8LF0D
Molecule Type:
Enzyme
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GLPG0634
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
GLPG0634
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
LMB-100
2
Unknown
Investigational
Unknown
Unknown
Neoplasms; Pancreatic Neoplasms; Adenocarcinoma of Lung; Mesothelioma
Elongation factor 2 disrupting agent
LMB-100
×
Maximum Phase:
2
First Approval:
None
UNII:
D6AT024T4P
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
1
2
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Maximum Phase
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Molecular Formula
Molecular Weight
ALogP
PSA