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Therapeutic Area
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EMERGENCY MEDICINE (3)
ENT (5)
EYE (23)
GASTROINTESTINAL (29)
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MUSCULOSKELETAL (28)
NEUROLOGY DRUGS & NERVOUS SYSTEM (50)
PEDIATRICS (27)
PHARMACOLOGY (8)
PREGNANCY AND GYNECOLOGY (30)
RESPIRATORY (42)
RHEUMATOLOGY (19)
OTHER (1482)
Therapeutic Indication
Adverse Reaction (System Organ Classification)
Mechanism of Action
Primary Target
Target Level
Level 1
Level 2
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Level 4
Level 5
Level 6
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Display Options:
Drug type
Therapeutic Area
Route of administration
Mechanism of Action
Indication
Status
Total:
10647
RONACALERET
2
Small molecule
Investigational
Unknown
Unknown
Fractures, Bone; Osteoporosis
Calcium sensing receptor antagonist
RONACALERET
×
Maximum Phase:
2
First Approval:
None
UNII:
DIH95YP7J3
Molecule Type:
Small molecule
Molecular Formula:
C25H31F2NO4
Molecular Weight:
447.52
AlogP:
3.9
PSA:
78.79
HBD:
3.0
HBA:
#RotB:
11.0
Source:
OMS405
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Peroxisome proliferator-activated receptor gamma agonist
OMS405
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
GINSENG
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
GINSENG
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
ECHINACEA ANGUSTIFOLIA
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
ECHINACEA ANGUSTIFOLIA
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
DANUSERTIB
2
Small molecule
Investigational
Unknown
Unknown
Leukemia; Multiple Myeloma; Prostatic Neoplasms, Castration-Resistant
Serine/threonine-protein kinase Aurora inhibitor
DANUSERTIB
×
Maximum Phase:
2
First Approval:
None
UNII:
M3X659D0FY
Molecule Type:
Small molecule
Molecular Formula:
C26H30N6O3
Molecular Weight:
474.57
AlogP:
2.64
PSA:
93.8
HBD:
2.0
HBA:
#RotB:
6.0
Source:
LAPULEUCEL-T
2
Cell
Investigational
Unknown
Unknown
Urinary Bladder Neoplasms
Unknown
LAPULEUCEL-T
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Cell
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
EPETIRIMOD ESYLATE
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
EPETIRIMOD ESYLATE
×
Maximum Phase:
2
First Approval:
None
UNII:
H92K6N217F
Molecule Type:
Small molecule
Molecular Formula:
C15H23N5O4S
Molecular Weight:
369.45
AlogP:
2.22
PSA:
69.62
HBD:
1.0
HBA:
#RotB:
2.0
Source:
IODOFILTIC ACID I 123
2
Small molecule
Investigational
Unknown
Unknown
Acute Coronary Syndrome
Unknown
IODOFILTIC ACID I 123
×
Maximum Phase:
2
First Approval:
None
UNII:
0J7USQ749M
Molecule Type:
Small molecule
Molecular Formula:
C22H35IO2
Molecular Weight:
454.43
AlogP:
7.24
PSA:
37.3
HBD:
1.0
HBA:
#RotB:
15.0
Source:
NAPTUMOMAB ESTAFENATOX
2
Antibody
Investigational
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell
Trophoblast glycoprotein other
NAPTUMOMAB ESTAFENATOX
×
Maximum Phase:
2
First Approval:
None
UNII:
93T929W6LC
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
PARATHYROID HORMONE RELATED PROTEIN (1-36)
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
PARATHYROID HORMONE RELATED PROTEIN (1-36)
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AFIMETORAN
2
Small molecule
Investigational
Unknown
Unknown
Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic
Unknown
AFIMETORAN
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C26H32N6O
Molecular Weight:
444.58
AlogP:
4.28
PSA:
92.31
HBD:
2.0
HBA:
#RotB:
5.0
Source:
FASORACETAM
2
Small molecule
Investigational
Unknown
Unknown
Attention Deficit Disorder with Hyperactivity
Unknown
FASORACETAM
×
Maximum Phase:
2
First Approval:
None
UNII:
42O8UF5CJB
Molecule Type:
Small molecule
Molecular Formula:
C10H16N2O2
Molecular Weight:
196.25
AlogP:
0.28
PSA:
49.41
HBD:
1.0
HBA:
#RotB:
1.0
Source:
MEROTOCIN
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
MEROTOCIN
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
LESOGABERAN
2
Small molecule
Investigational
Unknown
Unknown
Gastroesophageal Reflux
GABA-B receptor 1 agonist
LESOGABERAN
×
Maximum Phase:
2
First Approval:
None
UNII:
4D6Q6HGC7Z
Molecule Type:
Small molecule
Molecular Formula:
C3H9FNO2P
Molecular Weight:
141.08
AlogP:
-0.25
PSA:
63.32
HBD:
2.0
HBA:
#RotB:
3.0
Source:
ORVEPITANT MALEATE
2
Small molecule
Investigational
Unknown
Unknown
Cough
Unknown
ORVEPITANT MALEATE
×
Maximum Phase:
2
First Approval:
None
UNII:
HAX0H28B6W
Molecule Type:
Small molecule
Molecular Formula:
C35H39F7N4O6
Molecular Weight:
744.71
AlogP:
6.8
PSA:
47.1
HBD:
0.0
HBA:
#RotB:
4.0
Source:
ENVAFOLIMAB
2
Antibody
Investigational
Unknown
Unknown
Carcinoma, Hepatocellular; Biliary Tract Neoplasms; Breast Neoplasms; Hepatitis B, Chronic; Neoplasms
Programmed cell death 1 ligand 1 binding agent
ENVAFOLIMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
ES1M06M6QH
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BXT-51072
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
BXT-51072
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
STRONTIUM MALONATE
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
STRONTIUM MALONATE
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
HM781-36B
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
HM781-36B
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
AURICLOSENE MONOSODIUM MONOHYDRATE
2
Small molecule
Investigational
Unknown
Unknown
Conjunctivitis, Viral
Unknown
AURICLOSENE MONOSODIUM MONOHYDRATE
×
Maximum Phase:
2
First Approval:
None
UNII:
4787JWS9HN
Molecule Type:
Small molecule
Molecular Formula:
C4H10Cl2NNaO4S
Molecular Weight:
262.09
AlogP:
1.26
PSA:
57.61
HBD:
1.0
HBA:
#RotB:
3.0
Source:
CXL-1020
2
Small molecule
Investigational
Unknown
Unknown
Heart Failure
Unknown
CXL-1020
×
Maximum Phase:
2
First Approval:
None
UNII:
T7Q0XY74OK
Molecule Type:
Small molecule
Molecular Formula:
C7H9NO5S2
Molecular Weight:
251.28
AlogP:
-0.24
PSA:
100.54
HBD:
2.0
HBA:
#RotB:
3.0
Source:
IRX-2
2
Unknown
Investigational
Unknown
Unknown
Carcinoma, Hepatocellular; Breast Neoplasms; Carcinoma, Squamous Cell; Squamous Cell Carcinoma of Head and Neck; Squamous Intraepithelial Lesions
Unknown
IRX-2
×
Maximum Phase:
2
First Approval:
None
UNII:
ZDR4QSJ43F
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
OLEOYL
2
Small molecule
Investigational
Unknown
Unknown
Obesity
Unknown
OLEOYL
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C21H40NaO7P
Molecular Weight:
458.51
AlogP:
5.04
PSA:
113.29
HBD:
3.0
HBA:
#RotB:
20.0
Source:
PERFLENAPENT
2
Small molecule
Investigational
Unknown
Unknown
Glioblastoma
Unknown
PERFLENAPENT
×
Maximum Phase:
2
First Approval:
None
UNII:
483AU1Y5CZ
Molecule Type:
Small molecule
Molecular Formula:
C5F12
Molecular Weight:
288.03
AlogP:
4.02
PSA:
0.0
HBD:
0.0
HBA:
#RotB:
2.0
Source:
RV-521
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
RV-521
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Small molecule
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
EMACTUZUMAB
2
Antibody
Investigational
Unknown
Unknown
Lymphoma, Non-Hodgkin; Neoplasms
Macrophage colony stimulating factor receptor inhibitor
EMACTUZUMAB
×
Maximum Phase:
2
First Approval:
None
UNII:
6FY6EI1X8R
Molecule Type:
Antibody
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
BERUBICIN
2
Small molecule
Investigational
Unknown
Unknown
Glioblastoma
Unknown
BERUBICIN
×
Maximum Phase:
2
First Approval:
None
UNII:
6QPN83HK2M
Molecule Type:
Small molecule
Molecular Formula:
C34H35NO11
Molecular Weight:
633.65
AlogP:
2.23
PSA:
195.07
HBD:
5.0
HBA:
#RotB:
8.0
Source:
[18F]DPA-714
2
Small molecule
Investigational
Unknown
Unknown
Unknown
Unknown
[18F]DPA-714
×
Maximum Phase:
2
First Approval:
None
UNII:
0VMV8Z3972
Molecule Type:
Small molecule
Molecular Formula:
C22H27FN4O2
Molecular Weight:
397.48
AlogP:
3.77
PSA:
59.73
HBD:
0.0
HBA:
#RotB:
8.0
Source:
CPG-52852
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Melanoma
Toll-like receptor 7 agonist
CPG-52852
×
Maximum Phase:
2
First Approval:
None
UNII:
6PJC3KPK6S
Molecule Type:
Small molecule
Molecular Formula:
C17H23N5O2S
Molecular Weight:
361.47
AlogP:
2.06
PSA:
102.9
HBD:
2.0
HBA:
#RotB:
7.0
Source:
INDOXIMOD
2
Small molecule
Investigational
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung; Ependymoma; Gliosarcoma; Leukemia, Myeloid, Acute; Medulloblastoma; Breast Neoplasms; Melanoma; Prostatic Neoplasms
Unknown
INDOXIMOD
×
Maximum Phase:
2
First Approval:
None
UNII:
TX5CYN1KMZ
Molecule Type:
Small molecule
Molecular Formula:
C12H14N2O2
Molecular Weight:
218.26
AlogP:
1.13
PSA:
68.25
HBD:
2.0
HBA:
#RotB:
3.0
Source:
VEBICORVIR
2
Small molecule
Investigational
Unknown
Unknown
Hepatitis B, Chronic
Unknown
VEBICORVIR
×
Maximum Phase:
2
First Approval:
None
UNII:
None
Molecule Type:
Small molecule
Molecular Formula:
C19H12F3N3O4S2
Molecular Weight:
467.45
AlogP:
3.49
PSA:
105.23
HBD:
2.0
HBA:
#RotB:
3.0
Source:
IRX-4204
2
Small molecule
Investigational
Unknown
Unknown
Neoplasms; Parkinson Disease; Carcinoma, Non-Small-Cell Lung; Prostatic Neoplasms, Castration-Resistant
Retinoid X receptor agonist
IRX-4204
×
Maximum Phase:
2
First Approval:
None
UNII:
877M97Z38Y
Molecule Type:
Small molecule
Molecular Formula:
C24H32O2
Molecular Weight:
352.52
AlogP:
5.9
PSA:
37.3
HBD:
1.0
HBA:
#RotB:
4.0
Source:
ETO
2
Unknown
Investigational
Unknown
Unknown
Unknown
Unknown
ETO
×
Maximum Phase:
2
First Approval:
None
UNII:
Molecule Type:
Unknown
Molecular Formula:
Molecular Weight:
AlogP:
PSA:
HBD:
HBA:
#RotB:
Source:
VESATOLIMOD
2
Small molecule
Investigational
Unknown
Unknown
Hepatitis C; HIV Infections; Acquired Immunodeficiency Syndrome; Hepatitis B, Chronic
Toll-like receptor 7 activator
VESATOLIMOD
×
Maximum Phase:
2
First Approval:
None
UNII:
O8M467C50G
Molecule Type:
Small molecule
Molecular Formula:
C22H30N6O2
Molecular Weight:
410.52
AlogP:
2.79
PSA:
96.61
HBD:
2.0
HBA:
#RotB:
8.0
Source:
DAPANSUTRILE
2
Small molecule
Investigational
Unknown
Unknown
Heart Failure, Systolic; Melanoma; Schnitzler Syndrome; Severe Acute Respiratory Syndrome
NACHT, LRR and PYD domains-containing protein 3 inhibitor
DAPANSUTRILE
×
Maximum Phase:
2
First Approval:
None
UNII:
2Z03364G96
Molecule Type:
Small molecule
Molecular Formula:
C4H7NO2S
Molecular Weight:
133.17
AlogP:
-0.06
PSA:
57.93
HBD:
0.0
HBA:
#RotB:
2.0
Source:
1
2
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Compound Name
Maximum Phase
Compound Structure
Smile
Inchi
InchiKey
Compound Properties
Molecular Formula
Molecular Weight
ALogP
PSA