DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 10647


Unknown Approved Unknown Unknown Psoriasis; Skin Diseases; Severe Acute Respiratory Syndrome Unknown


Small molecule Approved OTHER ORAL Alzheimer Disease; Anus Neoplasms; Burkitt Lymphoma; Carcinoma, Ovarian Epithelial; Carcinoma, Squamous Cell; Carcinoma, Verrucous; Crohn Disease; Diffuse Intrinsic Pontine Glioma; Esophageal Neoplasms; Fallopian Tube Neoplasms; Glioma; Hypopharyngeal Neoplasms; Leukemia, Lymphoid; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myelomonocytic, Juvenile; Leukemia, Promyelocytic, Acute; Liver Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, T-Cell, Peripheral; Medulloblastoma; Melanoma; Neoplasms, Plasma Cell; Niemann-Pick Diseases; Oligodendroglioma; Oropharyngeal Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Salivary Gland Neoplasms; Schizophrenia; Skin Neoplasms; Small Cell Lung Carcinoma; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Adenocarcinoma, Follicular; Anemia, Sickle Cell; Astrocytoma; Brain Diseases; Brain Neoplasms; Breast Neoplasms; Breast Neoplasms, Male; Carcinoma, Medullary; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Colonic Neoplasms; Colorectal Neoplasms; Glioblastoma; Gliosarcoma; HIV Infections; Hodgkin Disease; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Mycosis Fungoides; Myelodysplastic Syndromes; Neuroblastoma; Ovarian Neoplasms; Pituitary ACTH Hypersecretion; Polycythemia Vera; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Sarcoma; Sezary Syndrome; Thrombocythemia, Essential; Thyroid Neoplasms; Urinary Bladder Neoplasms; Uveal Melanoma; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma; Mesothelioma; Multiple Myeloma; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous; Neoplasms Histone deacetylase 1 inhibitor

Small molecule

Approved

OTHER

ORAL

Alzheimer Disease; Anus Neoplasms; Burkitt Lymphoma; Carcinoma, Ovarian Epithelial; Carcinoma, Squamous Cell; Carcinoma, Verrucous; Crohn Disease; Diffuse Intrinsic Pontine Glioma; Esophageal Neoplasms; Fallopian Tube Neoplasms; Glioma; Hypopharyngeal Neoplasms; Leukemia, Lymphoid; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myelomonocytic, Juvenile; Leukemia, Promyelocytic, Acute; Liver Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, T-Cell, Peripheral; Medulloblastoma; Melanoma; Neoplasms, Plasma Cell; Niemann-Pick Diseases; Oligodendroglioma; Oropharyngeal Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Salivary Gland Neoplasms; Schizophrenia; Skin Neoplasms; Small Cell Lung Carcinoma; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Adenocarcinoma, Follicular; Anemia, Sickle Cell; Astrocytoma; Brain Diseases; Brain Neoplasms; Breast Neoplasms; Breast Neoplasms, Male; Carcinoma, Medullary; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Colonic Neoplasms; Colorectal Neoplasms; Glioblastoma; Gliosarcoma; HIV Infections; Hodgkin Disease; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Mycosis Fungoides; Myelodysplastic Syndromes; Neuroblastoma; Ovarian Neoplasms; Pituitary ACTH Hypersecretion; Polycythemia Vera; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Sarcoma; Sezary Syndrome; Thrombocythemia, Essential; Thyroid Neoplasms; Urinary Bladder Neoplasms; Uveal Melanoma; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma; Mesothelioma; Multiple Myeloma; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous; Neoplasms

Histone deacetylase 1 inhibitor


Small molecule Approved Unknown ORAL Alzheimer Disease; Amyotrophic Lateral Sclerosis; Restless Legs Syndrome; Supranuclear Palsy, Progressive; Parkinson Disease Unknown


Small molecule Approved IMMUNE SYSTEM; OTHER INTRAVENOUS; ORAL Glioblastoma; Leukemia; Leukemia, Myeloid, Acute; Neoplasms; Chagas Disease; Granulomatous Disease, Chronic; Mucormycosis; Onychomycosis; Candidiasis, Oral; Leukopenia; Aspergillosis; Candidiasis; Coccidioidomycosis; Mycoses; Neutropenia Cytochrome P450 51 inhibitor


Small molecule Approved Unknown Unknown Melanosis Sunscreen


Unknown Approved IMMUNE SYSTEM TOPICAL Condylomata Acuminata; Carcinoma, Basal Cell; Prostatic Neoplasms; Virus Diseases Unknown


Combination Approved Unknown Unknown Unknown Unknown


Small molecule Approved OTHER ORAL Alcohol Drinking; Alzheimer Disease; Amphetamine-Related Disorders; Cocaine-Related Disorders; Friedreich Ataxia; Machado-Joseph Disease; Marijuana Abuse; Parkinson Disease; Psychotic Disorders; Schizophrenia; Substance-Related Disorders; Acute Coronary Syndrome; Alcoholism; Dry Eye Syndromes; Lung Neoplasms; Neoplasms; Smoking Cessation; Eye Diseases; Tobacco Use Disorder Neuronal acetylcholine receptor; alpha4/beta2 partial agonist

Small molecule

Approved

OTHER

ORAL

Alcohol Drinking; Alzheimer Disease; Amphetamine-Related Disorders; Cocaine-Related Disorders; Friedreich Ataxia; Machado-Joseph Disease; Marijuana Abuse; Parkinson Disease; Psychotic Disorders; Schizophrenia; Substance-Related Disorders; Acute Coronary Syndrome; Alcoholism; Dry Eye Syndromes; Lung Neoplasms; Neoplasms; Smoking Cessation; Eye Diseases; Tobacco Use Disorder

Neuronal acetylcholine receptor; alpha4/beta2 partial agonist


Small molecule Approved IMMUNE SYSTEM; OTHER ORAL Autoimmune Diseases; HIV Infections; Infections Human immunodeficiency virus type 1 protease inhibitor


Small molecule Approved Unknown Unknown Hepatitis; Liver Cirrhosis; Hepatitis B, Chronic; Virus Diseases DNA polymerase/reverse transcriptase inhibitor


Small molecule Approved HEMATOLOGY; OTHER INTRAVENOUS Burkitt Lymphoma; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Hematologic Neoplasms; HIV Infections; Leukemia, Promyelocytic, Acute; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous; Mastocytosis, Systemic; Medulloblastoma; Multiple Myeloma; Neuroblastoma; Paraganglioma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Sarcoma, Synovial; Triple Negative Breast Neoplasms; Adenocarcinoma, Follicular; Anemia, Aplastic; Anemia, Sickle Cell; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Esophageal Neoplasms; Fallopian Tube Neoplasms; Granuloma, Lethal Midline; Hodgkin Disease; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lung Neoplasms; Lymphoma; Melanoma; Ovarian Neoplasms; Peritoneal Neoplasms; Primary Myelofibrosis; Severe Acute Respiratory Syndrome; Thalassemia; Thyroid Neoplasms; Graft vs Host Disease; Hematologic Diseases; Leukemia; Leukemia, Myeloid, Acute; Lymphoma, Large B-Cell, Diffuse; Lymphoma, T-Cell, Peripheral; Myeloproliferative Disorders; Purpura, Thrombocytopenic, Idiopathic; Thrombocytopenia; Anemia; Anemia, Refractory, with Excess of Blasts; Leukemia, Myeloid; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; Neoplasms DNA (cytosine-5)-methyltransferase 1 inhibitor

Small molecule

Approved

HEMATOLOGY; OTHER

INTRAVENOUS

Burkitt Lymphoma; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Hematologic Neoplasms; HIV Infections; Leukemia, Promyelocytic, Acute; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous; Mastocytosis, Systemic; Medulloblastoma; Multiple Myeloma; Neuroblastoma; Paraganglioma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Sarcoma, Synovial; Triple Negative Breast Neoplasms; Adenocarcinoma, Follicular; Anemia, Aplastic; Anemia, Sickle Cell; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Esophageal Neoplasms; Fallopian Tube Neoplasms; Granuloma, Lethal Midline; Hodgkin Disease; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lung Neoplasms; Lymphoma; Melanoma; Ovarian Neoplasms; Peritoneal Neoplasms; Primary Myelofibrosis; Severe Acute Respiratory Syndrome; Thalassemia; Thyroid Neoplasms; Graft vs Host Disease; Hematologic Diseases; Leukemia; Leukemia, Myeloid, Acute; Lymphoma, Large B-Cell, Diffuse; Lymphoma, T-Cell, Peripheral; Myeloproliferative Disorders; Purpura, Thrombocytopenic, Idiopathic; Thrombocytopenia; Anemia; Anemia, Refractory, with Excess of Blasts; Leukemia, Myeloid; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; Neoplasms

DNA (cytosine-5)-methyltransferase 1 inhibitor


Small molecule Approved OTHER; PEDIATRICS; RESPIRATORY INHALATION; NASAL Pulmonary Disease, Chronic Obstructive; Chronic Disease; Hypersensitivity; Respiratory Tract Diseases; Severe Acute Respiratory Syndrome; Asthma; Lung Diseases, Obstructive; Nasal Obstruction; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal Glucocorticoid receptor agonist


Small molecule Approved Unknown Unknown Gliosarcoma; Hemorrhagic Fever, Ebola; Kidney Diseases; Leukemia, Myeloid, Acute; Osteosarcoma; Adenocarcinoma; Adrenal Cortex Neoplasms; Ascites; Brain Neoplasms; Carcinoid Tumor; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Squamous Cell; Cholangiocarcinoma; Colorectal Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Glioblastoma; Glioma; Liver Neoplasms; Lung Neoplasms; Melanoma; Nasopharyngeal Carcinoma; Neoplasms, Germ Cell and Embryonal; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Pheochromocytoma; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Sarcoma, Alveolar Soft Part; Small Cell Lung Carcinoma; Stomach Neoplasms; Thymoma; Thymus Neoplasms; Thyroid Neoplasms; Urinary Bladder Neoplasms; Uveal Melanoma; von Hippel-Lindau Disease; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Kidney Neoplasms; Prostatic Neoplasms; Urogenital Neoplasms; Carcinoma, Renal Cell; Gastrointestinal Stromal Tumors; Neoplasms; Neuroendocrine Tumors Macrophage colony stimulating factor receptor inhibitor

Small molecule

Approved

Unknown

Gliosarcoma; Hemorrhagic Fever, Ebola; Kidney Diseases; Leukemia, Myeloid, Acute; Osteosarcoma; Adenocarcinoma; Adrenal Cortex Neoplasms; Ascites; Brain Neoplasms; Carcinoid Tumor; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Squamous Cell; Cholangiocarcinoma; Colorectal Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Glioblastoma; Glioma; Liver Neoplasms; Lung Neoplasms; Melanoma; Nasopharyngeal Carcinoma; Neoplasms, Germ Cell and Embryonal; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Pheochromocytoma; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Sarcoma, Alveolar Soft Part; Small Cell Lung Carcinoma; Stomach Neoplasms; Thymoma; Thymus Neoplasms; Thyroid Neoplasms; Urinary Bladder Neoplasms; Uveal Melanoma; von Hippel-Lindau Disease; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Kidney Neoplasms; Prostatic Neoplasms; Urogenital Neoplasms; Carcinoma, Renal Cell; Gastrointestinal Stromal Tumors; Neoplasms; Neuroendocrine Tumors

Macrophage colony stimulating factor receptor inhibitor


Protein Approved RHEUMATOLOGY IV (INFUSION) Amyotrophic Lateral Sclerosis; Anemia, Sickle Cell; Behcet Syndrome; Bronchiolitis Obliterans Syndrome; Myasthenia Gravis; Polychondritis, Relapsing; Scleroderma, Systemic; Thalassemia; Vitiligo; Alopecia; Alopecia Areata; Diabetes Mellitus, Type 1; Graft vs Host Disease; Hypertension; Immunoglobulin G4-Related Disease; Lupus Erythematosus, Systemic; Multiple Myeloma; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Myocarditis; Nephrotic Syndrome; Peanut Hypersensitivity; Polymyositis; Psoriasis; Sarcoidosis; Scleroderma, Diffuse; Spondylitis, Ankylosing; Takayasu Arteritis; Uveitis; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Colitis, Ulcerative; Crohn Disease; Dermatomyositis; Giant Cell Arteritis; Granulomatosis with Polyangiitis; Lupus Nephritis; Polymyalgia Rheumatica; Severe Acute Respiratory Syndrome; Sjogren's Syndrome; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Immune System Diseases T-lymphocyte activation antigen CD80 inhibitor

Protein

Approved

RHEUMATOLOGY

IV (INFUSION)

Amyotrophic Lateral Sclerosis; Anemia, Sickle Cell; Behcet Syndrome; Bronchiolitis Obliterans Syndrome; Myasthenia Gravis; Polychondritis, Relapsing; Scleroderma, Systemic; Thalassemia; Vitiligo; Alopecia; Alopecia Areata; Diabetes Mellitus, Type 1; Graft vs Host Disease; Hypertension; Immunoglobulin G4-Related Disease; Lupus Erythematosus, Systemic; Multiple Myeloma; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Myocarditis; Nephrotic Syndrome; Peanut Hypersensitivity; Polymyositis; Psoriasis; Sarcoidosis; Scleroderma, Diffuse; Spondylitis, Ankylosing; Takayasu Arteritis; Uveitis; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Colitis, Ulcerative; Crohn Disease; Dermatomyositis; Giant Cell Arteritis; Granulomatosis with Polyangiitis; Lupus Nephritis; Polymyalgia Rheumatica; Severe Acute Respiratory Syndrome; Sjogren's Syndrome; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Immune System Diseases

T-lymphocyte activation antigen CD80 inhibitor


Small molecule Approved Unknown Unknown Asthma; Bronchitis; Bronchitis, Chronic; Emphysema; Pulmonary Disease, Chronic Obstructive Unknown


Small molecule Approved Unknown Unknown Tonsillitis; Pain; Acid-Base Imbalance; Fluid Therapy pH lowering agent


Small molecule Approved Unknown Unknown Staphylococcal Infections; Infections; Impetigo; Staphylococcal Skin Infections 70S ribosome inhibitor


Small molecule Approved CARDIOVASCULAR; OTHER; RESPIRATORY ORAL Anemia, Sickle Cell; Altitude Sickness; Asthma; Hypoplastic Left Heart Syndrome; Severe Acute Respiratory Syndrome; Idiopathic Pulmonary Fibrosis; Vascular Diseases; Familial Primary Pulmonary Hypertension; Hypertension; Hypertension, Pulmonary; Pulmonary Arterial Hypertension Endothelin receptor, ET-A/ET-B antagonist


Protein Approved Unknown Unknown Acromegaly; Malignant Carcinoid Syndrome Somatostatin receptor 2 agonist


Small molecule Approved OTHER ORAL Head and Neck Neoplasms; Hepatitis C; Leukemia, Biphenotypic, Acute; Paraparesis, Tropical Spastic; HTLV-I Infections; Liver Cirrhosis, Biliary; Multiple Sclerosis, Relapsing-Remitting; Acquired Immunodeficiency Syndrome; HIV Infections; Infections; Virus Diseases Unknown


Small molecule Approved Unknown Unknown Hyperphosphatemia; Insulin Resistance; Kidney Failure, Chronic; Renal Insufficiency, Chronic Unknown


Small molecule Approved Unknown Unknown Heart Failure; Hypertension; Radiodermatitis; Alzheimer Disease; Autistic Disorder; Enteritis; Hypertension, Portal; Kidney Failure, Chronic; Lesch-Nyhan Syndrome; Liver Cirrhosis; Phenylketonurias; Pulmonary Disease, Chronic Obstructive Unknown


Small molecule Approved IMMUNE SYSTEM; OTHER; UROLOGY AND KIDNEY INTRAVENOUS Meningitis; Appendicitis; Cholecystitis; Pancreatitis; Peritonitis; Pneumonia; Pneumonia, Ventilator-Associated; Bacterial Infections; Intraabdominal Infections; Pyelonephritis; Urinary Tract Infections Bacterial penicillin-binding protein inhibitor


Protein Approved Unknown Unknown Carcinoma, Hepatocellular; Carcinoma, Merkel Cell; Diarrhea; Dumping Syndrome; Esophagitis, Peptic; Graves Ophthalmopathy; Hyperglycemia; Intestinal Diseases; Intestinal Obstruction; Neuroendocrine Tumors; Paraganglioma; Pheochromocytoma; Acromegaly; Carcinoid Heart Disease; Carcinoid Tumor; Endocrine Gland Neoplasms; Malignant Carcinoid Syndrome; Neoplasms; Pituitary Neoplasms; Polycystic Kidney, Autosomal Dominant; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms Unknown

Protein

Approved

Unknown

Carcinoma, Hepatocellular; Carcinoma, Merkel Cell; Diarrhea; Dumping Syndrome; Esophagitis, Peptic; Graves Ophthalmopathy; Hyperglycemia; Intestinal Diseases; Intestinal Obstruction; Neuroendocrine Tumors; Paraganglioma; Pheochromocytoma; Acromegaly; Carcinoid Heart Disease; Carcinoid Tumor; Endocrine Gland Neoplasms; Malignant Carcinoid Syndrome; Neoplasms; Pituitary Neoplasms; Polycystic Kidney, Autosomal Dominant; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms

Unknown


Small molecule Approved UROLOGY AND KIDNEY INTRAVENOUS Adenocarcinoma; Astrocytoma; Brain Neoplasms; Breast Neoplasms, Male; Carcinoma; Colonic Neoplasms; Colorectal Neoplasms; Diffuse Intrinsic Pontine Glioma; Genital Neoplasms, Female; Glioma; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lung Neoplasms; Oligodendroglioma; Paraganglioma; Peritoneal Neoplasms; Prostatic Neoplasms; Urethral Neoplasms; Uterine Cervical Neoplasms; Adenoma; Arthritis, Rheumatoid; Carcinoid Tumor; Carcinoma, Endometrioid; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Endometrial Neoplasms; Fallopian Tube Neoplasms; Ganglioneuroblastoma; Glioblastoma; Gliosarcoma; Hodgkin Disease; Insulinoma; Ischemia; Kidney Neoplasms; Leukemia; Leukemia, Myeloid, Acute; Liver Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Melanoma; Multiple Myeloma; Multiple Sclerosis, Relapsing-Remitting; Myelodysplastic Syndromes; Neuroblastoma; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Peripheral Arterial Disease; Prostatic Neoplasms, Castration-Resistant; Retroviridae Infections; Rhabdomyosarcoma; Sarcoma; Small Cell Lung Carcinoma; Somatostatinoma; Thyroid Neoplasms; Urinary Bladder Neoplasms; Breast Neoplasms; Hepatoblastoma; Lymphoma; Neoplasm Metastasis; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Carcinoma, Renal Cell; Lymphoma, Mantle-Cell; Neoplasms FK506-binding protein 1A inhibitor

Small molecule

Approved

UROLOGY AND KIDNEY

INTRAVENOUS

Adenocarcinoma; Astrocytoma; Brain Neoplasms; Breast Neoplasms, Male; Carcinoma; Colonic Neoplasms; Colorectal Neoplasms; Diffuse Intrinsic Pontine Glioma; Genital Neoplasms, Female; Glioma; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lung Neoplasms; Oligodendroglioma; Paraganglioma; Peritoneal Neoplasms; Prostatic Neoplasms; Urethral Neoplasms; Uterine Cervical Neoplasms; Adenoma; Arthritis, Rheumatoid; Carcinoid Tumor; Carcinoma, Endometrioid; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Endometrial Neoplasms; Fallopian Tube Neoplasms; Ganglioneuroblastoma; Glioblastoma; Gliosarcoma; Hodgkin Disease; Insulinoma; Ischemia; Kidney Neoplasms; Leukemia; Leukemia, Myeloid, Acute; Liver Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Melanoma; Multiple Myeloma; Multiple Sclerosis, Relapsing-Remitting; Myelodysplastic Syndromes; Neuroblastoma; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Peripheral Arterial Disease; Prostatic Neoplasms, Castration-Resistant; Retroviridae Infections; Rhabdomyosarcoma; Sarcoma; Small Cell Lung Carcinoma; Somatostatinoma; Thyroid Neoplasms; Urinary Bladder Neoplasms; Breast Neoplasms; Hepatoblastoma; Lymphoma; Neoplasm Metastasis; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Carcinoma, Renal Cell; Lymphoma, Mantle-Cell; Neoplasms

FK506-binding protein 1A inhibitor

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

ORAL

Carcinoma, Non-Small-Cell Lung; Head and Neck Neoplasms; Esophageal Neoplasms; Glioma; Multiple Sclerosis; Neoplasms; Schizophrenia; Sleep Initiation and Maintenance Disorders; Stroke; Brain Injuries; Depressive Disorder; Disorders of Excessive Somnolence; Fatigue; Obesity; Sleep Apnea Syndromes; Attention Deficit Disorder with Hyperactivity; Narcolepsy; Sleep Apnea, Obstructive; Sleep Wake Disorders

Dopamine transporter inhibitor

Small molecule

Approved

Unknown

Breast Neoplasms; Bronchiolitis Obliterans Syndrome; Chordoma; Colonic Neoplasms; Huntington Disease; Cerebellar Ataxia; Glioma; Graft vs Host Disease; Hypertension, Pulmonary; Leukemia, Myeloid, Acute; Melanoma; Neuroma, Acoustic; Paraganglioma; Parkinson Disease; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Synovitis, Pigmented Villonodular; Alzheimer Disease; Gastrointestinal Stromal Tumors; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Neoplasms; Sarcoma

Unknown


Small molecule Approved Unknown Unknown Unknown Unknown

Small molecule

Approved

Unknown

ORAL

Carcinoma, Renal Cell; Endometrial Neoplasms; Prostatic Neoplasms, Castration-Resistant; Renal Insufficiency, Chronic; Thyroid Neoplasms; Urinary Bladder Neoplasms; Adenocarcinoma; Bile Duct Neoplasms; Brain Neoplasms; Carcinoma, Ductal; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colorectal Neoplasms; Esophageal Neoplasms; Gallbladder Neoplasms; Melanoma; Ovarian Neoplasms; Pancreatic Neoplasms; Paraganglioma; Peritoneal Neoplasms; Pituitary Neoplasms; Stomach Neoplasms; Uterine Cervical Neoplasms; Brain Diseases; Breast Neoplasms; Head and Neck Neoplasms; Neoplasms; Sarcoma

Unknown

Antibody

Approved

HEMATOLOGY

IV (INFUSION)

End Stage Liver Disease; Graft vs Host Disease; Hemolysis; Anemia, Hemolytic, Autoimmune; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Dermatomyositis; Diabetes Mellitus; Glomerulonephritis, Membranoproliferative; Macular Degeneration; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; Thrombocytopenia; Guillain-Barre Syndrome; Hemolytic-Uremic Syndrome; Leukemia; Myasthenia Gravis; Neuromyelitis Optica; Atypical Hemolytic Uremic Syndrome; Hemoglobinuria; Hemoglobinuria, Paroxysmal

Complement C5 inhibitor


Enzyme Approved OTHER INJECTION Empyema, Pleural; Pulmonary Embolism; ST Elevation Myocardial Infarction; Empyema; Infections; Stroke; Thrombosis Urokinase-type plasminogen activator exogenous protein

Small molecule

Approved

IMMUNE SYSTEM; OTHER

ORAL

Hypertriglyceridemia; AIDS Dementia Complex; Arthritis, Rheumatoid; Cognitive Dysfunction; Graft vs Host Disease; Hematologic Neoplasms; Hodgkin Disease; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Myelodysplastic Syndromes; Sarcoma, Kaposi; Severe Acute Respiratory Syndrome; Stroke; Acquired Immunodeficiency Syndrome; Infections; HIV Infections; Virus Diseases

C-C chemokine receptor type 5 antagonist


Small molecule Approved Unknown Unknown Coronary Disease; Coronary Artery Disease Diagnostic agent


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER TRANSDERMAL Alzheimer Disease; Fibromyalgia; Stroke; Substance-Related Disorders; Parkinson Disease; Restless Legs Syndrome D2-like dopamine receptor agonist


Small molecule Approved Unknown Unknown Breast Neoplasms; Neoplasms; Ovarian Neoplasms; Parkinson Disease; Scleroderma, Systemic; Leukemia, Myelogenous, Chronic, BCR-ABL Positive Bcr/Abl fusion protein inhibitor