DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 10647


Unknown Approved Unknown Unknown Unknown Unknown


Small molecule Approved IMMUNE SYSTEM; OTHER ORAL Cholangitis, Sclerosing; Neoplasms; Persian Gulf Syndrome; Renal Insufficiency, Chronic; Alzheimer Disease; Anemia, Sickle Cell; Breast Neoplasms; Diverticulitis; Dyspepsia; Heart Failure, Systolic; Hepatitis C; HIV Infections; Intestinal Pseudo-Obstruction; Rosacea; Vaginosis, Bacterial; Brain Diseases; Clostridium Infections; Colitis, Collagenous; Crohn Disease; Helicobacter Infections; Hepatitis, Alcoholic; Irritable Bowel Syndrome; Liver Cirrhosis; Parkinson Disease; Peritonitis; Rectal Neoplasms; Diarrhea; Hepatic Encephalopathy; Infections Bacterial DNA-directed RNA polymerase inhibitor

Small molecule

Approved

IMMUNE SYSTEM; OTHER

ORAL

Cholangitis, Sclerosing; Neoplasms; Persian Gulf Syndrome; Renal Insufficiency, Chronic; Alzheimer Disease; Anemia, Sickle Cell; Breast Neoplasms; Diverticulitis; Dyspepsia; Heart Failure, Systolic; Hepatitis C; HIV Infections; Intestinal Pseudo-Obstruction; Rosacea; Vaginosis, Bacterial; Brain Diseases; Clostridium Infections; Colitis, Collagenous; Crohn Disease; Helicobacter Infections; Hepatitis, Alcoholic; Irritable Bowel Syndrome; Liver Cirrhosis; Parkinson Disease; Peritonitis; Rectal Neoplasms; Diarrhea; Hepatic Encephalopathy; Infections

Bacterial DNA-directed RNA polymerase inhibitor


Small molecule Approved Unknown Unknown Urinary Bladder, Overactive; Polyuria; Urinary Incontinence Unknown


Small molecule Approved CANCER INJECTION; INTRAVENOUS Leukemia, Promyelocytic, Acute; Lymphoma, Follicular; Graft vs Host Disease; Hematologic Diseases; Histiocytosis, Langerhans-Cell; Hodgkin Disease; Leukemia, Biphenotypic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myelomonocytic, Chronic; Lymphoma; Lymphoma, Non-Hodgkin; Multiple Myeloma; Myelodysplastic Syndromes; Osteopetrosis; Leukemia; Leukemia, Myeloid, Acute; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma DNA inhibitor

Small molecule

Approved

CANCER

INJECTION; INTRAVENOUS

Leukemia, Promyelocytic, Acute; Lymphoma, Follicular; Graft vs Host Disease; Hematologic Diseases; Histiocytosis, Langerhans-Cell; Hodgkin Disease; Leukemia, Biphenotypic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myelomonocytic, Chronic; Lymphoma; Lymphoma, Non-Hodgkin; Multiple Myeloma; Myelodysplastic Syndromes; Osteopetrosis; Leukemia; Leukemia, Myeloid, Acute; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma

DNA inhibitor


Small molecule Approved Unknown Unknown Carcinoma, Squamous Cell; Cheilitis; Uterine Cervical Dysplasia; Acne Vulgaris; Carcinoma, Basal Cell; Keratosis, Actinic; Skin Aging; Neoplasms Unknown


Small molecule Approved CANCER; OTHER INJECTION; INTRAVENOUS; IV (INFUSION) Chordoma; Endometrial Neoplasms; Glioma; Lymphoma; Lymphoma, Non-Hodgkin; Melanoma; Primary Myelofibrosis; Thymoma; Thymus Neoplasms; Triple Negative Breast Neoplasms; Uveal Melanoma; Adenocarcinoma; Biliary Tract Neoplasms; Breast Neoplasms; Breast Neoplasms, Male; Carcinoma, Large Cell; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Colorectal Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Liver Neoplasms; Lymphoma, Large B-Cell, Diffuse; Medulloblastoma; Meningeal Carcinomatosis; Mesothelioma, Malignant; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neuroendocrine Tumors; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Sarcoma; Thyroid Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Adenocarcinoma of Lung; Carcinoma; Carcinoma, Non-Small-Cell Lung; Head and Neck Neoplasms; Lung Neoplasms; Small Cell Lung Carcinoma; Stomach Neoplasms; Uterine Cervical Neoplasms; Mesothelioma; Neoplasms Dihydrofolate reductase inhibitor

Small molecule

Approved

CANCER; OTHER

INJECTION; INTRAVENOUS; IV (INFUSION)

Chordoma; Endometrial Neoplasms; Glioma; Lymphoma; Lymphoma, Non-Hodgkin; Melanoma; Primary Myelofibrosis; Thymoma; Thymus Neoplasms; Triple Negative Breast Neoplasms; Uveal Melanoma; Adenocarcinoma; Biliary Tract Neoplasms; Breast Neoplasms; Breast Neoplasms, Male; Carcinoma, Large Cell; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Colorectal Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Liver Neoplasms; Lymphoma, Large B-Cell, Diffuse; Medulloblastoma; Meningeal Carcinomatosis; Mesothelioma, Malignant; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neuroendocrine Tumors; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Sarcoma; Thyroid Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Adenocarcinoma of Lung; Carcinoma; Carcinoma, Non-Small-Cell Lung; Head and Neck Neoplasms; Lung Neoplasms; Small Cell Lung Carcinoma; Stomach Neoplasms; Uterine Cervical Neoplasms; Mesothelioma; Neoplasms

Dihydrofolate reductase inhibitor


Protein Approved Unknown Unknown Fever; Pain Voltage-gated N-type calcium channel alpha-1B subunit blocker


Unknown Approved Unknown Unknown Unknown Unknown


Small molecule Approved Unknown Unknown Amyotrophic Lateral Sclerosis; Urinary Bladder, Overactive; Polyuria; Urinary Incontinence Unknown


Small molecule Approved Unknown Unknown Adenocarcinoma of Lung; Astrocytoma; Brain Neoplasms; Carcinoma, Renal Cell; Central Nervous System Neoplasms; Colonic Neoplasms; Glioma; Hemorrhagic Fever, Ebola; Hepatitis C, Chronic; Melanoma; Multiple Myeloma; Oligodendroglioma; Pharyngeal Neoplasms; Rectal Neoplasms; Adenocarcinoma, Bronchiolo-Alveolar; Adenomatous Polyposis Coli; Breast Neoplasms; Carcinoma; Diffuse Intrinsic Pontine Glioma; Digestive System Diseases; Ependymoma; Esophageal Neoplasms; Fallopian Tube Neoplasms; Glioblastoma; Gliosarcoma; Hematologic Neoplasms; Leukemia; Leukemia, Myeloid, Acute; Liver Neoplasms; Mesothelioma; Myelodysplastic Syndromes; Nasopharyngeal Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuroendocrine Tumors; Ovarian Neoplasms; Polycythemia Vera; Prostatic Neoplasms, Castration-Resistant; Psoriasis; Skin Neoplasms; Thymoma; Urinary Bladder Neoplasms; Biliary Tract Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colorectal Neoplasms; Head and Neck Neoplasms; Lung Neoplasms; Mouth Neoplasms; Neoplasm Metastasis; Neoplasms; Pancreatic Neoplasms Unknown

Small molecule

Approved

Unknown

Adenocarcinoma of Lung; Astrocytoma; Brain Neoplasms; Carcinoma, Renal Cell; Central Nervous System Neoplasms; Colonic Neoplasms; Glioma; Hemorrhagic Fever, Ebola; Hepatitis C, Chronic; Melanoma; Multiple Myeloma; Oligodendroglioma; Pharyngeal Neoplasms; Rectal Neoplasms; Adenocarcinoma, Bronchiolo-Alveolar; Adenomatous Polyposis Coli; Breast Neoplasms; Carcinoma; Diffuse Intrinsic Pontine Glioma; Digestive System Diseases; Ependymoma; Esophageal Neoplasms; Fallopian Tube Neoplasms; Glioblastoma; Gliosarcoma; Hematologic Neoplasms; Leukemia; Leukemia, Myeloid, Acute; Liver Neoplasms; Mesothelioma; Myelodysplastic Syndromes; Nasopharyngeal Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuroendocrine Tumors; Ovarian Neoplasms; Polycythemia Vera; Prostatic Neoplasms, Castration-Resistant; Psoriasis; Skin Neoplasms; Thymoma; Urinary Bladder Neoplasms; Biliary Tract Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colorectal Neoplasms; Head and Neck Neoplasms; Lung Neoplasms; Mouth Neoplasms; Neoplasm Metastasis; Neoplasms; Pancreatic Neoplasms

Unknown


Small molecule Approved Unknown Unknown Amphetamine-Related Disorders; Autistic Disorder; Tinnitus; Child Development Disorders, Pervasive; Cocaine-Related Disorders; Essential Tremor; Feeding and Eating Disorders; Fragile X Syndrome; Anxiety; Dementia; Depressive Disorder; Schizophrenia; Alcoholism Unknown


Small molecule Approved Unknown Unknown Prostatic Hyperplasia; Urinary Bladder, Overactive; Urinary Incontinence, Urge Muscarinic acetylcholine receptor M2 antagonist


Enzyme Approved OTHER INJECTION Anemia, Hemolytic; Diabetes Mellitus, Type 1; Hypersensitivity; Neuralgia; Breast Neoplasms; Graves Ophthalmopathy; Leukemia, Biphenotypic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Melanoma; Muscle Spasticity; Neoplasms; Prostatic Neoplasms; Amyloidosis, Familial; Bursitis; Carcinoma, Non-Small-Cell Lung; Coronary Disease; Lymphoma; Lymphoma, Follicular; Multiple Myeloma; Myocardial Infarction; Myocardial Ischemia; Pain Hyaluronic acid hydrolytic enzyme

Enzyme

Approved

OTHER

INJECTION

Anemia, Hemolytic; Diabetes Mellitus, Type 1; Hypersensitivity; Neuralgia; Breast Neoplasms; Graves Ophthalmopathy; Leukemia, Biphenotypic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Melanoma; Muscle Spasticity; Neoplasms; Prostatic Neoplasms; Amyloidosis, Familial; Bursitis; Carcinoma, Non-Small-Cell Lung; Coronary Disease; Lymphoma; Lymphoma, Follicular; Multiple Myeloma; Myocardial Infarction; Myocardial Ischemia; Pain

Hyaluronic acid hydrolytic enzyme


Antibody Approved Unknown Unknown Unknown Diagnostic


Small molecule Approved OTHER ORAL Myelodysplastic Syndromes; Primary Myelofibrosis; Scleroderma, Systemic; Crohn Disease; Dry Eye Syndromes; Leukemia; Leukemia, Myeloid, Acute; Lymphoma; Renal Insufficiency, Chronic; Cytomegalovirus Infections; Diabetes Mellitus, Type 1; Graft vs Host Disease; Lupus Erythematosus, Systemic; Lupus Nephritis; Nephrotic Syndrome; Sarcoidosis, Pulmonary; Uveitis, Intermediate; Immune System Diseases Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor

Small molecule

Approved

OTHER

ORAL

Myelodysplastic Syndromes; Primary Myelofibrosis; Scleroderma, Systemic; Crohn Disease; Dry Eye Syndromes; Leukemia; Leukemia, Myeloid, Acute; Lymphoma; Renal Insufficiency, Chronic; Cytomegalovirus Infections; Diabetes Mellitus, Type 1; Graft vs Host Disease; Lupus Erythematosus, Systemic; Lupus Nephritis; Nephrotic Syndrome; Sarcoidosis, Pulmonary; Uveitis, Intermediate; Immune System Diseases

Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitor


Small molecule Approved OTHER; RESPIRATORY INHALATION Cystic Fibrosis; Neoplasms; Spinal Cord Injuries; Asthma; Bronchial Spasm; Bronchitis, Chronic; Emphysema; Lung Diseases, Obstructive; Pulmonary Disease, Chronic Obstructive Muscarinic acetylcholine receptor M3 antagonist


Small molecule Approved Unknown Unknown Alcoholism; Brain Injuries; Hallucinations; Erectile Dysfunction; Parkinson Disease Unknown


Small molecule Approved Unknown Unknown Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Crohn Disease; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dyspepsia; Eczema; Head and Neck Neoplasms; Propionic Acidemia; Renal Insufficiency, Chronic; Anxiety Disorders; Breast Neoplasms; Clostridium Infections; Cross Infection; Cystic Fibrosis; Heart Failure; Herpes Labialis; Herpes Simplex; Irritable Bowel Syndrome; Lymphoma; Multiple Myeloma; Periodontitis; Prostatic Neoplasms, Castration-Resistant; Thalassemia; Wounds and Injuries; Colorectal Neoplasms; Coronary Disease; Diarrhea; Fetal Growth Retardation; Malnutrition; Mucositis; Multiple Organ Failure; Muscular Dystrophy, Duchenne; Neoplasms; Peripheral Nervous System Diseases; Premature Birth; Sepsis; Severe Acute Respiratory Syndrome; Stomatitis; Anemia, Sickle Cell; Short Bowel Syndrome Unknown

Small molecule

Approved

Unknown

Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Crohn Disease; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dyspepsia; Eczema; Head and Neck Neoplasms; Propionic Acidemia; Renal Insufficiency, Chronic; Anxiety Disorders; Breast Neoplasms; Clostridium Infections; Cross Infection; Cystic Fibrosis; Heart Failure; Herpes Labialis; Herpes Simplex; Irritable Bowel Syndrome; Lymphoma; Multiple Myeloma; Periodontitis; Prostatic Neoplasms, Castration-Resistant; Thalassemia; Wounds and Injuries; Colorectal Neoplasms; Coronary Disease; Diarrhea; Fetal Growth Retardation; Malnutrition; Mucositis; Multiple Organ Failure; Muscular Dystrophy, Duchenne; Neoplasms; Peripheral Nervous System Diseases; Premature Birth; Sepsis; Severe Acute Respiratory Syndrome; Stomatitis; Anemia, Sickle Cell; Short Bowel Syndrome

Unknown


Small molecule Approved Unknown Unknown Amphetamine-Related Disorders; Emergence Delirium; Stress Disorders, Post-Traumatic; Stroke; Alcoholism; Attention Deficit Disorder with Hyperactivity; Colorectal Neoplasms; Diabetes Mellitus; Diabetic Nephropathies; Fatigue Syndrome, Chronic; Lung Diseases, Interstitial; Multiple Sclerosis; Myalgia; Neuralgia; Pain; Anxiety; Anxiety Disorders; Back Pain; Biliary Dyskinesia; Burning Mouth Syndrome; Cognitive Dysfunction; Dementia; Depressive Disorder; Depressive Disorder, Major; Diabetic Neuropathies; Fibromyalgia; Low Back Pain; Osteoarthritis; Osteoarthritis, Knee; Parkinson Disease; Peripheral Nervous System Diseases; Schizophrenia; Shoulder Pain; Urinary Incontinence; Urinary Incontinence, Stress Unknown

Small molecule

Approved

Unknown

Amphetamine-Related Disorders; Emergence Delirium; Stress Disorders, Post-Traumatic; Stroke; Alcoholism; Attention Deficit Disorder with Hyperactivity; Colorectal Neoplasms; Diabetes Mellitus; Diabetic Nephropathies; Fatigue Syndrome, Chronic; Lung Diseases, Interstitial; Multiple Sclerosis; Myalgia; Neuralgia; Pain; Anxiety; Anxiety Disorders; Back Pain; Biliary Dyskinesia; Burning Mouth Syndrome; Cognitive Dysfunction; Dementia; Depressive Disorder; Depressive Disorder, Major; Diabetic Neuropathies; Fibromyalgia; Low Back Pain; Osteoarthritis; Osteoarthritis, Knee; Parkinson Disease; Peripheral Nervous System Diseases; Schizophrenia; Shoulder Pain; Urinary Incontinence; Urinary Incontinence, Stress

Unknown


Small molecule Approved Unknown Unknown Brain Neoplasms; Lymphoma Unknown


Small molecule Approved OTHER ORAL Breast Carcinoma In Situ; Carcinoma, Merkel Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Chagas Cardiomyopathy; Colorectal Neoplasms; Fatty Liver; Lymphoma, Non-Hodgkin; Melanoma; Metabolic Syndrome; Ovarian Neoplasms; Pancreatic Neoplasms; Severe Acute Respiratory Syndrome; Urinary Bladder Neoplasms; Wounds and Injuries; Aggression; Autistic Disorder; Bipolar Disorder; Breast Neoplasms; Child Development Disorders, Pervasive; Cognitive Dysfunction; Depression, Postpartum; Depressive Disorder; Depressive Disorder, Major; Diabetes Mellitus, Type 1; Dysthymic Disorder; Epilepsy; Glomerulonephritis, IGA; Inflammation; Lichen Planus, Oral; Myositis; Oral Ulcer; Periodontitis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Psychotic Disorders; Renal Insufficiency, Chronic; Sarcopenia; Schizophrenia; Stomatitis; Acne Vulgaris; Alzheimer Disease; Atrial Fibrillation; Attention Deficit Disorder with Hyperactivity; Dry Eye Syndromes; Endocrine System Diseases; Heart Diseases; Heart Failure; HIV Infections; Hypercholesterolemia; Hyperlipidemia, Familial Combined; Hyperlipoproteinemia Type II; Hypertension; Hypertriglyceridemia; Insulin Resistance; Intermittent Claudication; Language Disorders; Lipid Metabolism Disorders; Metabolic Diseases; Myocardial Infarction; Myocardial Ischemia; Non-alcoholic Fatty Liver Disease; Peripheral Arterial Disease; Pyelonephritis; Vascular Diseases; Cardiovascular Diseases; Diabetes Mellitus; Diabetes Mellitus, Type 2; Hypothyroidism Unknown

Small molecule

Approved

OTHER

ORAL

Breast Carcinoma In Situ; Carcinoma, Merkel Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Chagas Cardiomyopathy; Colorectal Neoplasms; Fatty Liver; Lymphoma, Non-Hodgkin; Melanoma; Metabolic Syndrome; Ovarian Neoplasms; Pancreatic Neoplasms; Severe Acute Respiratory Syndrome; Urinary Bladder Neoplasms; Wounds and Injuries; Aggression; Autistic Disorder; Bipolar Disorder; Breast Neoplasms; Child Development Disorders, Pervasive; Cognitive Dysfunction; Depression, Postpartum; Depressive Disorder; Depressive Disorder, Major; Diabetes Mellitus, Type 1; Dysthymic Disorder; Epilepsy; Glomerulonephritis, IGA; Inflammation; Lichen Planus, Oral; Myositis; Oral Ulcer; Periodontitis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Psychotic Disorders; Renal Insufficiency, Chronic; Sarcopenia; Schizophrenia; Stomatitis; Acne Vulgaris; Alzheimer Disease; Atrial Fibrillation; Attention Deficit Disorder with Hyperactivity; Dry Eye Syndromes; Endocrine System Diseases; Heart Diseases; Heart Failure; HIV Infections; Hypercholesterolemia; Hyperlipidemia, Familial Combined; Hyperlipoproteinemia Type II; Hypertension; Hypertriglyceridemia; Insulin Resistance; Intermittent Claudication; Language Disorders; Lipid Metabolism Disorders; Metabolic Diseases; Myocardial Infarction; Myocardial Ischemia; Non-alcoholic Fatty Liver Disease; Peripheral Arterial Disease; Pyelonephritis; Vascular Diseases; Cardiovascular Diseases; Diabetes Mellitus; Diabetes Mellitus, Type 2; Hypothyroidism

Unknown


Small molecule Approved OTHER INHALATION Asthma; Humeral Fractures; Myocardial Infarction; Heart Arrest; Lung Neoplasms; Multiple Organ Failure; Pulmonary Disease, Chronic Obstructive; Renal Insufficiency, Chronic; Scleroderma, Systemic; Raynaud Disease; Respiratory Distress Syndrome; Shock, Septic; Hypertension, Pulmonary; Pulmonary Arterial Hypertension; Thrombosis Prostanoid IP receptor agonist

Small molecule

Approved

OTHER

INHALATION

Asthma; Humeral Fractures; Myocardial Infarction; Heart Arrest; Lung Neoplasms; Multiple Organ Failure; Pulmonary Disease, Chronic Obstructive; Renal Insufficiency, Chronic; Scleroderma, Systemic; Raynaud Disease; Respiratory Distress Syndrome; Shock, Septic; Hypertension, Pulmonary; Pulmonary Arterial Hypertension; Thrombosis

Prostanoid IP receptor agonist


Protein Approved OTHER SUBCUTANEOUS Hypogonadism; Infertility; Infertility, Female; Ovulation Induction Luteinizing hormone/Choriogonadotropin receptor agonist


Antibody Approved OTHER; UROLOGY AND KIDNEY INTRAVENOUS Adenomatous Polyposis Coli; Carcinoma, Merkel Cell; Carcinoma, Pancreatic Ductal; Cystadenoma, Serous; Desmoplastic Small Round Cell Tumor; Diabetic Neuropathies; Endometriosis; Inflammatory Breast Neoplasms; Lymphedema; Meningitis, Aseptic; Myeloproliferative Disorders; Neoplasm Metastasis; Neoplasms, Cystic, Mucinous, and Serous; Neuroma, Acoustic; Neuromyelitis Optica; Pharyngeal Neoplasms; Pulmonary Veno-Occlusive Disease; Renal Insufficiency, Chronic; von Hippel-Lindau Disease; Adenocarcinoma, Clear Cell; Adenoma; Adrenal Cortex Neoplasms; Ascites; Astrocytoma; Biliary Tract Neoplasms; Brain Injuries; Breast Neoplasms, Male; Carcinoid Tumor; Carcinoma; Carcinoma, Endometrioid; Carcinoma, Islet Cell; Carcinoma, Large Cell; Carcinoma, Neuroendocrine; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Central Serous Chorioretinopathy; Cholangiocarcinoma; Choriocarcinoma; Coronavirus Infections; Diffuse Intrinsic Pontine Glioma; Digestive System Diseases; Endometrial Neoplasms; Ependymoma; Esophageal Neoplasms; Fibrosarcoma; Gallbladder Neoplasms; Gestational Trophoblastic Disease; Glioma; Granuloma, Lethal Midline; Head and Neck Neoplasms; Hemangiosarcoma; Hemorrhage; Histiocytoma, Benign Fibrous; Hodgkin Disease; Insulinoma; Keloid; Leiomyosarcoma; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liposarcoma; Liver Neoplasms; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Medulloblastoma; Melanoma; Meningioma; Multiple Myeloma; Myelodysplastic Syndromes; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasms, Germ Cell and Embryonal; Neoplasms, Plasma Cell; Neurilemmoma; Neuroblastoma; Neuroectodermal Tumors, Primitive, Peripheral; Neuroendocrine Tumors; Oligodendroglioma; Optic Neuropathy, Ischemic; Osteosarcoma; Papilloma; Pinealoma; Pneumonia; Primary Myelofibrosis; Pulmonary Fibrosis; Retroviridae Infections; Rhabdomyosarcoma; Rhabdomyosarcoma, Alveolar; Sarcoma; Sarcoma, Alveolar Soft Part; Sarcoma, Kaposi; Sarcoma, Synovial; Sex Cord-Gonadal Stromal Tumors; Small Cell Lung Carcinoma; Somatostatinoma; Thymoma; Thyroid Neoplasms; Triple Negative Breast Neoplasms; Trophoblastic Tumor, Placental Site; Urinary Bladder Neoplasms; Uterine Neoplasms; Uveal Melanoma; Vascular Diseases; Vitreous Hemorrhage; Adenocarcinoma; Adenocarcinoma of Lung; Brain Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Ovarian Epithelial; Choroidal Neovascularization; Choroiditis; Colorectal Neoplasms, Hereditary Nonpolyposis; Corneal Neovascularization; Diabetic Retinopathy; Gastrointestinal Stromal Tumors; Glaucoma; Gliosarcoma; Inflammation; Kidney Neoplasms; Lung Neoplasms; Lymphoma, Follicular; Macular Degeneration; Macular Edema; Mesothelioma; Myopia; Pancreatic Neoplasms; Paraganglioma; Pleural Effusion; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pterygium; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Retinal Detachment; Retinal Diseases; Retinal Telangiectasis; Retinal Vein Occlusion; Retinopathy of Prematurity; Severe Acute Respiratory Syndrome; Stomach Neoplasms; Telangiectasia, Hereditary Hemorrhagic; Telangiectasis; Uveitis; Uveomeningoencephalitic Syndrome; Wet Macular Degeneration; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Colonic Neoplasms; Colorectal Neoplasms; Fallopian Tube Neoplasms; Glioblastoma; Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Retinal Neovascularization; Uterine Cervical Neoplasms Vascular endothelial growth factor A inhibitor

Antibody

Approved

OTHER; UROLOGY AND KIDNEY

INTRAVENOUS

Adenomatous Polyposis Coli; Carcinoma, Merkel Cell; Carcinoma, Pancreatic Ductal; Cystadenoma, Serous; Desmoplastic Small Round Cell Tumor; Diabetic Neuropathies; Endometriosis; Inflammatory Breast Neoplasms; Lymphedema; Meningitis, Aseptic; Myeloproliferative Disorders; Neoplasm Metastasis; Neoplasms, Cystic, Mucinous, and Serous; Neuroma, Acoustic; Neuromyelitis Optica; Pharyngeal Neoplasms; Pulmonary Veno-Occlusive Disease; Renal Insufficiency, Chronic; von Hippel-Lindau Disease; Adenocarcinoma, Clear Cell; Adenoma; Adrenal Cortex Neoplasms; Ascites; Astrocytoma; Biliary Tract Neoplasms; Brain Injuries; Breast Neoplasms, Male; Carcinoid Tumor; Carcinoma; Carcinoma, Endometrioid; Carcinoma, Islet Cell; Carcinoma, Large Cell; Carcinoma, Neuroendocrine; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Central Serous Chorioretinopathy; Cholangiocarcinoma; Choriocarcinoma; Coronavirus Infections; Diffuse Intrinsic Pontine Glioma; Digestive System Diseases; Endometrial Neoplasms; Ependymoma; Esophageal Neoplasms; Fibrosarcoma; Gallbladder Neoplasms; Gestational Trophoblastic Disease; Glioma; Granuloma, Lethal Midline; Head and Neck Neoplasms; Hemangiosarcoma; Hemorrhage; Histiocytoma, Benign Fibrous; Hodgkin Disease; Insulinoma; Keloid; Leiomyosarcoma; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liposarcoma; Liver Neoplasms; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Medulloblastoma; Melanoma; Meningioma; Multiple Myeloma; Myelodysplastic Syndromes; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasms, Germ Cell and Embryonal; Neoplasms, Plasma Cell; Neurilemmoma; Neuroblastoma; Neuroectodermal Tumors, Primitive, Peripheral; Neuroendocrine Tumors; Oligodendroglioma; Optic Neuropathy, Ischemic; Osteosarcoma; Papilloma; Pinealoma; Pneumonia; Primary Myelofibrosis; Pulmonary Fibrosis; Retroviridae Infections; Rhabdomyosarcoma; Rhabdomyosarcoma, Alveolar; Sarcoma; Sarcoma, Alveolar Soft Part; Sarcoma, Kaposi; Sarcoma, Synovial; Sex Cord-Gonadal Stromal Tumors; Small Cell Lung Carcinoma; Somatostatinoma; Thymoma; Thyroid Neoplasms; Triple Negative Breast Neoplasms; Trophoblastic Tumor, Placental Site; Urinary Bladder Neoplasms; Uterine Neoplasms; Uveal Melanoma; Vascular Diseases; Vitreous Hemorrhage; Adenocarcinoma; Adenocarcinoma of Lung; Brain Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Ovarian Epithelial; Choroidal Neovascularization; Choroiditis; Colorectal Neoplasms, Hereditary Nonpolyposis; Corneal Neovascularization; Diabetic Retinopathy; Gastrointestinal Stromal Tumors; Glaucoma; Gliosarcoma; Inflammation; Kidney Neoplasms; Lung Neoplasms; Lymphoma, Follicular; Macular Degeneration; Macular Edema; Mesothelioma; Myopia; Pancreatic Neoplasms; Paraganglioma; Pleural Effusion; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pterygium; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Retinal Detachment; Retinal Diseases; Retinal Telangiectasis; Retinal Vein Occlusion; Retinopathy of Prematurity; Severe Acute Respiratory Syndrome; Stomach Neoplasms; Telangiectasia, Hereditary Hemorrhagic; Telangiectasis; Uveitis; Uveomeningoencephalitic Syndrome; Wet Macular Degeneration; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Colonic Neoplasms; Colorectal Neoplasms; Fallopian Tube Neoplasms; Glioblastoma; Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Retinal Neovascularization; Uterine Cervical Neoplasms

Vascular endothelial growth factor A inhibitor


Protein Approved OTHER INTRAVENOUS Obsessive-Compulsive Disorder; Autistic Disorder Secretin receptor agonist


Small molecule Approved Unknown Unknown Constipation Unknown


Small molecule Approved Unknown Unknown Bronchitis, Chronic; Renal Insufficiency; Spinal Cord Injuries; Asthma; Pulmonary Disease, Chronic Obstructive Unknown


Small molecule Approved Unknown Unknown Brain Injuries; Heart Failure; Liver Cirrhosis; Hyponatremia; Cardiovascular Diseases Unknown


Small molecule Approved Unknown Unknown Graft vs Host Disease; Neoplasms; Aspergillosis; Leukemia; Candidemia; Candidiasis; Candidiasis, Invasive; Candidiasis, Oral; Mycoses Unknown

Antibody

Approved

Unknown

Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; HIV Infections; Leukemia, Biphenotypic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Liver Neoplasms; Lymphoma, B-Cell; Lymphoma, Follicular; Ovarian Neoplasms; Panuveitis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency, Chronic; Schizophrenia; Small Cell Lung Carcinoma; Urinary Bladder Neoplasms; Uveitis, Intermediate; Uveitis, Posterior; Amyotrophic Lateral Sclerosis; Astrocytoma; Behcet Syndrome; Breast Neoplasms; Castleman Disease; Depressive Disorder, Major; Dermatomyositis; Diabetes Mellitus, Type 1; Erdheim-Chester Disease; Familial Mediterranean Fever; Fever; Fibrous Dysplasia of Bone; Graft vs Host Disease; Graves Ophthalmopathy; Hematologic Neoplasms; Hypertension, Pulmonary; Leukemia; Lung Diseases; Lymphohistiocytosis, Hemophagocytic; Lymphoma, Mantle-Cell; Macrophage Activation Syndrome; Melanoma; Motor Neuron Disease; Multiple Myeloma; Myasthenia Gravis; Neoplasms; Neuromyelitis Optica; Non-ST Elevated Myocardial Infarction; Pancreatic Neoplasms; Pneumonia, Viral; Polychondritis, Relapsing; Polymyositis; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Respiratory Distress Syndrome; Schnitzler Syndrome; Still's Disease, Adult-Onset; Uveitis; Virus Diseases; Epilepsy; Influenza, Human; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Pneumonia; Polymyalgia Rheumatica; Sepsis; Spondylitis, Ankylosing; Takayasu Arteritis; Arthritis, Juvenile; Arthritis, Rheumatoid; COVID-19; Cytokine Release Syndrome; Giant Cell Arteritis; Immune System Diseases; Scleroderma, Systemic; Severe Acute Respiratory Syndrome

Interleukin-6 receptor alpha subunit inhibitor


Small molecule Approved OTHER; PEDIATRICS ORAL Hemorrhage; HIV Infections; Virus Diseases Human immunodeficiency virus type 1 protease inhibitor


Combination Approved Unknown Unknown Unknown Unknown

Protein

Approved

OTHER

INJECTION

Alopecia; Epidermolysis Bullosa; Graft vs Host Disease; Granulomatous Disease, Chronic; Hematologic Neoplasms; Hodgkin Disease; Leukemia, Plasma Cell; Lymphoma, Non-Hodgkin; Multiple Sclerosis; Neoplasms, Neuroepithelial; Stevens-Johnson Syndrome; X-Linked Combined Immunodeficiency Diseases; Asthma; Colonic Neoplasms; HIV Infections; Leukemia, Myeloid, Acute; Lymphoma, T-Cell; Myelodysplastic Syndromes; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Leukemia; Lymphoma; Multiple Myeloma; Neoplasms; Mucositis; Stomatitis

Fibroblast growth factor receptor 2 agonist


Protein Approved OTHER INJECTION Cystic Fibrosis; Atherosclerosis; Coronary Disease; Hypercholesterolemia; Hypertension; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2 Insulin receptor agonist


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS ORAL Neuralgia; Epilepsy; Dementia; Depressive Disorder; Epilepsia Partialis Continua; Low Back Pain; Pain; Schizophrenia; Anxiety; Lennox Gastaut Syndrome; Seizures GABA-A receptor; anion channel positive allosteric modulator