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Total: 10647
Small molecule
Approved
Unknown
Unknown
Constipation
Osmotic agent
Small molecule
Approved
Unknown
Unknown
Migraine Disorders
Calcitonin gene-related peptide type 1 receptor antagonist
Small molecule
Approved
Unknown
Unknown
Migraine Disorders
Serotonin 1f (5-HT1f) receptor agonist
Small molecule
Approved
Unknown
Unknown
Carcinoma, Non-Small-Cell Lung
Hepatocyte growth factor receptor inhibitor
Small molecule
Approved
Unknown
Unknown
Pain
GABA-A receptor; anion channel positive allosteric modulator
Unknown
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Kidney Diseases; Liver Diseases; Sleep Apnea, Obstructive; Sleep Disorders, Circadian Rhythm; Sleep Initiation and Maintenance Disorders
Orexin receptor 1 antagonist
Small molecule
Approved
Unknown
Unknown
Leukemia, Myeloid, Acute; Lymphoma; Prostatic Neoplasms, Castration-Resistant; Keratosis, Actinic
Tyrosine-protein kinase SRC inhibitor
Small molecule
Approved
Unknown
Unknown
Astrocytoma; Biliary Tract Neoplasms; Cholangiocarcinoma; Colonic Neoplasms; Kidney Neoplasms; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Optic Nerve Glioma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Rectal Neoplasms; Sarcoma, Kaposi; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Adenocarcinoma; Adenocarcinoma, Follicular; Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Colorectal Neoplasms; Gallbladder Neoplasms; Liver Neoplasms; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Melanoma; Multiple Myeloma; Neurofibroma, Plexiform; Neurofibromatosis 1; Pancreatic Neoplasms; Sarcoma; Stomach Neoplasms; Carcinoma, Non-Small-Cell Lung; Thyroid Neoplasms; Neoplasms
Dual specificity mitogen-activated protein kinase kinase 1 inhibitor
Antibody
Approved
Unknown
Unknown
Anemia, Hemolytic, Autoimmune; Colorectal Neoplasms; Hematologic Neoplasms; Immune System Diseases; Amyloidosis, Familial; Leukemia, Myeloid, Acute; Leukemia, T-Cell; Lymphoma; Paraproteinemias; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Smoldering Multiple Myeloma; Multiple Myeloma; Neoplasms
Lymphocyte differentiation antigen CD38 inhibitor
Small molecule
Approved
Unknown
Unknown
Diabetes Mellitus, Type 2; Hypercholesterolemia; Lipid Metabolism Disorders; Hyperlipidemias; Atherosclerosis; Cardiovascular Diseases; Coronary Artery Disease; Hyperlipoproteinemia Type II
ATP-citrate synthase inhibitor
Small molecule
Approved
Unknown
Unknown
Unknown
GABA-B receptor agonist
Small molecule
Approved
Unknown
Unknown
Pituitary ACTH Hypersecretion
Cytochrome P450 11B1 inhibitor
Small molecule
Approved
Unknown
Unknown
Psoriasis; Trigeminal Neuralgia; Migraine Disorders
Calcitonin gene-related peptide type 1 receptor antagonist
Unknown
Approved
Unknown
Unknown
Unknown
Unknown
Combination
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Glycogen Storage Disease Type I; Migraine Disorders; Amyotrophic Lateral Sclerosis; Ataxia Telangiectasia; Glycogen Storage Disease; Glycogen Storage Disease Type VII; Hemiplegia; Huntington Disease; Rett Syndrome
Supplement
Small molecule
Approved
Unknown
Unknown
Multiple Sclerosis
Sphingosine 1-phosphate receptor Edg-1 modulator
Small molecule
Approved
Unknown
Unknown
Glioma; Leukemia, Mast-Cell; Mastocytosis, Systemic; Gastrointestinal Stromal Tumors; Neoplasms
Platelet-derived growth factor receptor alpha inhibitor
Oligosaccharide
Approved
Unknown
Unknown
Renal Insufficiency, Chronic; Anemia; Anemia, Iron-Deficiency
Supplement
Small molecule
Approved
Unknown
Unknown
Leukemia, Myeloid, Acute; Endometrial Neoplasms; Myeloproliferative Disorders; Urinary Bladder Neoplasms; Urogenital Neoplasms; Cholangiocarcinoma; Neoplasms
Fibroblast growth factor receptor 1 inhibitor
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Alzheimer Disease
Unknown
Small molecule
Approved
Unknown
Unknown
Breast Neoplasms; Carcinoma, Hepatocellular; Friedreich Ataxia; Neoplasms; Colorectal Neoplasms; Crohn Disease; Severe Acute Respiratory Syndrome; Cytomegalovirus Infections; Fever; Malaria, Falciparum; Malaria, Vivax; Schistosomiasis; Schistosomiasis haematobia; Malaria
Unknown
Small molecule
Approved
Unknown
Unknown
Breast Neoplasms; Glioblastoma; Liver Diseases; Carcinoma, Hepatocellular; Kidney Neoplasms; Lung Neoplasms; Melanoma; Carcinoma, Non-Small-Cell Lung; Sarcoma; Neoplasms
Hepatocyte growth factor receptor inhibitor
Combination
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Dwarfism, Pituitary
Growth hormone receptor agonist
Small molecule
Approved
Unknown
Unknown
Alzheimer Disease; Chronic Traumatic Encephalopathy; Cognitive Dysfunction
Diagnostic agent
Combination
Approved
Unknown
Unknown
Unknown
Unknown
Unknown
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Pneumonia, Viral; Hemorrhagic Fever, Ebola; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome
Replicase polyprotein 1ab inhibitor
Small molecule
Approved
Unknown
ORAL
Multiple Sclerosis, Relapsing-Remitting; Multiple Sclerosis
Kelch-like ECH-associated protein 1 inhibitor
Small molecule
Approved
Unknown
Unknown
Kidney Diseases; Liver Diseases; Cushing Syndrome; Essential Hypertension; Hyperaldosteronism; Hypertension; Pituitary ACTH Hypersecretion; Adrenal Gland Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Carcinoid Tumor; Endometrial Neoplasms; Glioblastoma; Leukemia; Stomach Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Mesothelioma; Sarcoma; Ovarian Neoplasms; Neoplasms; Small Cell Lung Carcinoma
DNA negative modulator
Oligonucleotide
Approved
Unknown
Unknown
Hyperoxaluria, Primary
Hydroxyacid oxidase 1 mRNA RNAi inhibitor