DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 10647


Protein Approved Unknown Unknown Hemoglobinuria, Paroxysmal; Amyotrophic Lateral Sclerosis; Hemoglobinuria; Myasthenia Gravis; Severe Acute Respiratory Syndrome Complement C5 inhibitor


Small molecule Approved Unknown Unknown Hematologic Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Uterine Cervical Neoplasms; Uterine Neoplasms; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Lymphoma, Follicular; Meningioma; Multiple Myeloma; Prostatic Neoplasms; Stomach Neoplasms; Triple Negative Breast Neoplasms; Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Neoplasms Serine/threonine-protein kinase AKT inhibitor

Small molecule

Approved

Unknown

Hematologic Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Uterine Cervical Neoplasms; Uterine Neoplasms; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Lymphoma, Follicular; Meningioma; Multiple Myeloma; Prostatic Neoplasms; Stomach Neoplasms; Triple Negative Breast Neoplasms; Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Neoplasms

Serine/threonine-protein kinase AKT inhibitor


Small molecule Approved Unknown Unknown Hemoglobinuria, Paroxysmal; Kidney Diseases; Liver Diseases; Glomerulonephritis; Glomerulonephritis, Membranous; Lupus Nephritis; Macular Degeneration; Atypical Hemolytic Uremic Syndrome; Glomerulonephritis, IGA; Glomerulonephritis, Membranoproliferative; Hemoglobinuria Complement factor B inhibitor


Small molecule Approved Unknown Unknown Dry Eye Syndromes; Ossification, Heterotopic; Myositis Ossificans Retinoic acid receptor gamma agonist


Small molecule Approved Unknown Unknown Alopecia Areata; Dermatitis, Atopic; Eosinophilic Esophagitis; Inflammatory Bowel Diseases; Liver Cirrhosis, Biliary; Pyoderma; Colitis, Ulcerative; Crohn Disease Sphingosine 1-phosphate receptor Edg-1 agonist


Small molecule Approved Unknown Unknown Colitis, Ulcerative; Muscular Dystrophy, Duchenne Glucocorticoid receptor agonist


Small molecule Approved Unknown Unknown Asthma; Severe Acute Respiratory Syndrome; Migraine Disorders Calcitonin-gene-related peptide receptor, CALCRL/RAMP1 antagonist


Small molecule Approved Unknown Unknown Carcinoma, Non-Small-Cell Lung; Leukemia, Myeloid; Polycythemia Vera; Thrombocythemia, Essential; Carcinoma, Pancreatic Ductal; Neoplasms; Primary Myelofibrosis Tyrosine-protein kinase JAK1 inhibitor


Oligonucleotide Approved Unknown Unknown Amyloidosis; Amyloid Neuropathies, Familial Transthyretin mRNA antisense inhibitor


Small molecule Approved Unknown Unknown Hypertension; Glomerulosclerosis, Focal Segmental; Glomerulonephritis, IGA Endothelin receptor ET-A antagonist


Small molecule Approved Unknown Unknown Amyloidosis; Amyloid Neuropathies, Familial; Cardiovascular Diseases Transthyretin stabiliser


Small molecule Approved Unknown Unknown Endometrial Neoplasms; Neoplasms; Breast Neoplasms PI3-kinase p110-alpha subunit inhibitor


Small molecule Approved Unknown Unknown Breast Neoplasms; Carcinoma, Renal Cell; HIV Infections; Melanoma; Waldenstrom Macroglobulinemia; Neutropenia; Neoplasms C-X-C chemokine receptor type 4 antagonist


Small molecule Approved Unknown Unknown Liver Diseases; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasms Epidermal growth factor receptor erbB1 inhibitor


Small molecule Approved Unknown Unknown Diagnostic Imaging Diagnostic


Small molecule Approved Unknown Unknown Kidney Diseases; Liver Diseases; Geographic Atrophy; Glomerulonephritis, Membranoproliferative; Severe Acute Respiratory Syndrome; Hemoglobinuria; Hemoglobinuria, Paroxysmal; Hemolysis Complement factor D inhibitor


Small molecule Approved Unknown Unknown Liver Diseases; Cholangitis, Sclerosing; Hyperlipidemias; Hyperlipoproteinemia Type II; Non-alcoholic Fatty Liver Disease; Liver Cirrhosis, Biliary Peroxisome proliferator-activated receptor delta agonist


Small molecule Approved Unknown Unknown Asthma; Cystic Fibrosis; Severe Acute Respiratory Syndrome; Pulmonary Disease, Chronic Obstructive Phosphodiesterase 3 inhibitor


Small molecule Approved Unknown Unknown Liver Diseases; Carcinoma, Non-Small-Cell Lung; Neoplasms CD74-ROS1 inhibitor


Small molecule Approved Unknown Unknown Kidney Diseases; Liver Diseases; Essential Hypertension; Hypertension Endothelin receptor, ET-A/ET-B antagonist


Oligonucleotide Approved Unknown Unknown Breast Neoplasms; Lymphoma; Neuroblastoma; Carcinoma, Non-Small-Cell Lung; Multiple Myeloma; Myelodysplastic Syndromes; Polycythemia Vera; Thrombocythemia, Essential; Neoplasms; Primary Myelofibrosis Telomerase reverse transcriptase inhibitor


Small molecule Approved Unknown Unknown Dyslipidemias; Hypercholesterolemia; Hyperlipoproteinemia Type II; Non-alcoholic Fatty Liver Disease Thyroid hormone receptor beta-1 agonist


Small molecule Approved Unknown Unknown Liver Diseases; Anemia; Renal Insufficiency, Chronic Egl nine homolog 1 inhibitor


Small molecule Approved Unknown Unknown Gaucher Disease; Niemann-Pick Disease, Type C; Amyotrophic Lateral Sclerosis; Myositis, Inclusion Body Unknown


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved Unknown Unknown Glioma; Liver Diseases; Neoplasms; Paraganglioma; Astrocytoma; Oligodendroglioma IDH1/IDH2 inhibitor


Small molecule Approved Unknown Unknown Crohn Disease; Hodgkin Disease; Polycythemia Vera; Arthritis, Juvenile; Leukemia, Lymphocytic, Chronic, B-Cell; Multiple Myeloma; Myeloproliferative Disorders; Muscular Dystrophy, Duchenne Unknown


Small molecule Approved Unknown Unknown Atrial Flutter; Heart Arrest; Tachycardia, Supraventricular; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiovascular Diseases; Shock, Septic Beta-1 adrenergic receptor antagonist


Small molecule Approved Unknown Unknown Liver Diseases; Cholangitis, Sclerosing; Diabetes Mellitus, Type 2; Non-alcoholic Fatty Liver Disease; Liver Cirrhosis, Biliary; Cholangitis Peroxisome proliferator-activated receptor alpha agonist


Small molecule Approved Unknown Unknown Lung Neoplasms; Melanoma; Carcinoma, Non-Small-Cell Lung ALK tyrosine kinase receptor inhibitor

Small molecule

Investigational

Unknown

Bone Marrow Failure Disorders; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Graft vs Host Disease; Hematologic Neoplasms; Hemoglobinuria; Hodgkin Disease; Lymphoma, Non-Hodgkin; Multiple Myeloma; Nijmegen Breakage Syndrome; Shwachman-Diamond Syndrome; Leukemia, Myeloid, Acute; Melanoma; Myelodysplastic Syndromes; Ovarian Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma, Ewing; Hematopoietic Stem Cell Transplantation; Neoplasms

DNA cross-linking agent


Small molecule Approved Unknown Unknown Colorectal Neoplasms; Glioma; Carcinoma, Non-Small-Cell Lung; Neoplasms; Neurofibromatosis 1 Dual specificity mitogen-activated protein kinase kinase 1 inhibitor


Small molecule Investigational Unknown Unknown Carcinoma, Hepatocellular; Multiple Myeloma; Neoplasms; Waldenstrom Macroglobulinemia 26S proteasome inhibitor


Unknown Investigational Unknown Unknown Unknown Unknown


Unknown Investigational Unknown Unknown Neoplasms Unknown