DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 6532


Small molecule Approved OTHER IMPLANTATION; INHALATION; NASAL; TOPICAL Alopecia Areata; Hypersensitivity; Otitis Media with Effusion; Spinal Cord Injuries; Anemia, Sickle Cell; Dermatitis, Atopic; Eosinophilic Esophagitis; Pemphigoid, Bullous; Psoriasis; Radiodermatitis; Breast Neoplasms; Hypertrophy; Pulmonary Disease, Chronic Obstructive; Rhinitis, Allergic, Perennial; Severe Acute Respiratory Syndrome; Sinusitis; Sleep Apnea, Obstructive; Asthma; Lung Diseases, Obstructive; Nasal Obstruction; Nasal Polyps; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal; Skin Diseases Glucocorticoid receptor agonist

Small molecule

Approved

OTHER

IMPLANTATION; INHALATION; NASAL; TOPICAL

Alopecia Areata; Hypersensitivity; Otitis Media with Effusion; Spinal Cord Injuries; Anemia, Sickle Cell; Dermatitis, Atopic; Eosinophilic Esophagitis; Pemphigoid, Bullous; Psoriasis; Radiodermatitis; Breast Neoplasms; Hypertrophy; Pulmonary Disease, Chronic Obstructive; Rhinitis, Allergic, Perennial; Severe Acute Respiratory Syndrome; Sinusitis; Sleep Apnea, Obstructive; Asthma; Lung Diseases, Obstructive; Nasal Obstruction; Nasal Polyps; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal; Skin Diseases

Glucocorticoid receptor agonist


Small molecule Approved OTHER; RESPIRATORY ORAL Osteomyelitis; Bronchitis, Chronic; Infections; Maxillary Sinusitis; Otitis Media; Pharyngitis; Sinusitis; Tonsillitis; Urinary Tract Infections Bacterial penicillin-binding protein inhibitor


Small molecule Approved Unknown Unknown Non-alcoholic Fatty Liver Disease Unknown


Small molecule Approved Unknown Unknown Cardiovascular Diseases Unknown


Small molecule Approved GASTROINTESTINAL; OTHER; RESPIRATORY INJECTION; ORAL; OTIC Arthritis, Rheumatoid; Carcinoma, Pancreatic Ductal; Diabetic Foot; Dysentery, Bacillary; Erectile Dysfunction; Gastroenteritis; Hearing Loss; Hepatitis, Alcoholic; Hepatitis C; Leukemia, Myeloid, Acute; Liver Cirrhosis, Alcoholic; Lung Diseases; Lymphoma; Neoplasms; Osteomyelitis; Periapical Periodontitis; Pseudomonas Infections; Purpura, Thrombocytopenic, Idiopathic; Rhinoscleroma; Amyotrophic Lateral Sclerosis; Anthrax; Cataract; Corneal Ulcer; Crohn Disease; Cystic Fibrosis; Endophthalmitis; Leukemia, Lymphocytic, Chronic, B-Cell; Pancreatic Neoplasms; Breast Neoplasms; Bronchiectasis; Communicable Diseases; Diarrhea; Digestive System Diseases; Fever; Hypertriglyceridemia; Kidney Calculi; Lipid Metabolism Disorders; Liver Abscess; Neutropenia; Otitis Media; Peritonitis; Plague; Pneumonia; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Sepsis; Urinary Bladder Neoplasms; Urolithiasis; Bacterial Infections; Bronchitis, Chronic; Cystitis; Eye Infections; Gonorrhea; Infections; Intraabdominal Infections; Otitis Externa; Prostatitis; Pyelonephritis; Sinusitis; Typhoid Fever; Urinary Tract Infections Bacterial DNA gyrase inhibitor

Small molecule

Approved

GASTROINTESTINAL; OTHER; RESPIRATORY

INJECTION; ORAL; OTIC

Arthritis, Rheumatoid; Carcinoma, Pancreatic Ductal; Diabetic Foot; Dysentery, Bacillary; Erectile Dysfunction; Gastroenteritis; Hearing Loss; Hepatitis, Alcoholic; Hepatitis C; Leukemia, Myeloid, Acute; Liver Cirrhosis, Alcoholic; Lung Diseases; Lymphoma; Neoplasms; Osteomyelitis; Periapical Periodontitis; Pseudomonas Infections; Purpura, Thrombocytopenic, Idiopathic; Rhinoscleroma; Amyotrophic Lateral Sclerosis; Anthrax; Cataract; Corneal Ulcer; Crohn Disease; Cystic Fibrosis; Endophthalmitis; Leukemia, Lymphocytic, Chronic, B-Cell; Pancreatic Neoplasms; Breast Neoplasms; Bronchiectasis; Communicable Diseases; Diarrhea; Digestive System Diseases; Fever; Hypertriglyceridemia; Kidney Calculi; Lipid Metabolism Disorders; Liver Abscess; Neutropenia; Otitis Media; Peritonitis; Plague; Pneumonia; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Sepsis; Urinary Bladder Neoplasms; Urolithiasis; Bacterial Infections; Bronchitis, Chronic; Cystitis; Eye Infections; Gonorrhea; Infections; Intraabdominal Infections; Otitis Externa; Prostatitis; Pyelonephritis; Sinusitis; Typhoid Fever; Urinary Tract Infections

Bacterial DNA gyrase inhibitor


Small molecule Approved Unknown Unknown Glioma; Immunoblastic Lymphadenopathy; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma, T-Cell, Peripheral; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Biphenotypic, Acute; Lymphoma; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Multiple Sclerosis, Relapsing-Remitting; Myelodysplastic Syndromes; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Neoplasms Unknown

Small molecule

Approved

Unknown

Glioma; Immunoblastic Lymphadenopathy; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma, T-Cell, Peripheral; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Biphenotypic, Acute; Lymphoma; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Multiple Sclerosis, Relapsing-Remitting; Myelodysplastic Syndromes; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Neoplasms

Unknown


Small molecule Approved Unknown Unknown Cardiovascular Diseases; Diabetes Mellitus; Heart Failure; Hypertension; Myocardial Infarction; Stroke Angiotensin-converting enzyme inhibitor


Small molecule Approved Unknown Unknown Depressive Disorder; Panic Disorder; Stress Disorders, Post-Traumatic; Bipolar Disorder; Depressive Disorder, Major; Obsessive-Compulsive Disorder Serotonin transporter inhibitor


Small molecule Approved GASTROINTESTINAL; OTHER ORAL; RECTAL Berylliosis; HIV Infections; Malnutrition; Adenoma; Colitis; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Digestive System Diseases; Diverticulum, Colon; Eosinophilic Esophagitis; Inflammatory Bowel Diseases; Colitis, Collagenous; Colitis, Lymphocytic; Crohn Disease; Diverticular Diseases; Diverticulitis; Irritable Bowel Syndrome; Colitis, Ulcerative; Proctitis Arachidonate 5-lipoxygenase inhibitor

Small molecule

Approved

GASTROINTESTINAL; OTHER

ORAL; RECTAL

Berylliosis; HIV Infections; Malnutrition; Adenoma; Colitis; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Digestive System Diseases; Diverticulum, Colon; Eosinophilic Esophagitis; Inflammatory Bowel Diseases; Colitis, Collagenous; Colitis, Lymphocytic; Crohn Disease; Diverticular Diseases; Diverticulitis; Irritable Bowel Syndrome; Colitis, Ulcerative; Proctitis

Arachidonate 5-lipoxygenase inhibitor


Small molecule Approved Unknown Unknown Dysuria; Pain; Urinary Retention Unknown


Small molecule Approved Unknown Unknown Myasthenia Gravis; Glaucoma Unknown


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved OTHER INJECTION; ORAL Severe Combined Immunodeficiency; Castleman Disease; Infections; Leukemia-Lymphoma, Adult T-Cell; Liver Cirrhosis, Biliary; Lymphoma; Lymphoma, AIDS-Related; Paraparesis, Tropical Spastic; Sarcoma, Kaposi; Acquired Immunodeficiency Syndrome; AIDS Dementia Complex; AIDS-Related Complex; Diarrhea; Pneumonia, Pneumocystis; Pregnancy; Severe Acute Respiratory Syndrome; Tuberculosis; Autoimmune Diseases; HIV Infections; Virus Diseases Human immunodeficiency virus type 1 reverse transcriptase inhibitor

Small molecule

Approved

OTHER

INJECTION; ORAL

Severe Combined Immunodeficiency; Castleman Disease; Infections; Leukemia-Lymphoma, Adult T-Cell; Liver Cirrhosis, Biliary; Lymphoma; Lymphoma, AIDS-Related; Paraparesis, Tropical Spastic; Sarcoma, Kaposi; Acquired Immunodeficiency Syndrome; AIDS Dementia Complex; AIDS-Related Complex; Diarrhea; Pneumonia, Pneumocystis; Pregnancy; Severe Acute Respiratory Syndrome; Tuberculosis; Autoimmune Diseases; HIV Infections; Virus Diseases

Human immunodeficiency virus type 1 reverse transcriptase inhibitor


Small molecule Approved OTHER ORAL Unknown Norepinephrine transporter releasing agent


Small molecule Approved CARDIOVASCULAR; OTHER ORAL Asthma; Inflammation; Leukemia, Myeloid, Acute; Metabolic Diseases; Porokeratosis; Stroke; Arthritis, Rheumatoid; Breast Neoplasms; Carotid Stenosis; Cerebrovascular Disorders; Cognitive Dysfunction; Fragile X Syndrome; HIV Infections; Intracranial Arteriosclerosis; Intracranial Arteriovenous Malformations; Learning Disabilities; Melanoma; Neurofibromatosis 1; Ovarian Neoplasms; Parkinson Disease; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Rett Syndrome; Xanthomatosis, Cerebrotendinous; Heart Diseases; Intermittent Claudication; Lipid Metabolism Disorders; Myocardial Ischemia; Peripheral Vascular Diseases; Atherosclerosis; Cardiovascular Diseases; Coronary Artery Disease; Coronary Disease; Hypercholesterolemia HMG-CoA reductase inhibitor

Small molecule

Approved

CARDIOVASCULAR; OTHER

ORAL

Asthma; Inflammation; Leukemia, Myeloid, Acute; Metabolic Diseases; Porokeratosis; Stroke; Arthritis, Rheumatoid; Breast Neoplasms; Carotid Stenosis; Cerebrovascular Disorders; Cognitive Dysfunction; Fragile X Syndrome; HIV Infections; Intracranial Arteriosclerosis; Intracranial Arteriovenous Malformations; Learning Disabilities; Melanoma; Neurofibromatosis 1; Ovarian Neoplasms; Parkinson Disease; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Rett Syndrome; Xanthomatosis, Cerebrotendinous; Heart Diseases; Intermittent Claudication; Lipid Metabolism Disorders; Myocardial Ischemia; Peripheral Vascular Diseases; Atherosclerosis; Cardiovascular Diseases; Coronary Artery Disease; Coronary Disease; Hypercholesterolemia

HMG-CoA reductase inhibitor


Small molecule Approved OTHER ORAL Fibrosis; Glucose Intolerance; Huntington Disease; Liver Cirrhosis; Obesity; Severe Acute Respiratory Syndrome; Adenomatous Polyposis Coli; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Cholangitis, Sclerosing; Cholestasis; Colorectal Neoplasms; Diabetes Mellitus; Heart Failure; Hepatitis D; Inflammation; Jaundice, Obstructive; Non-alcoholic Fatty Liver Disease; Parkinson Disease; Pregnancy; Cholelithiasis; Cholestasis, Intrahepatic; Diabetes, Gestational; Diabetes Mellitus, Type 2; Hepatitis C, Chronic; Liver Diseases; Liver Cirrhosis, Biliary Bile acid receptor FXR agonist

Small molecule

Approved

OTHER

ORAL

Fibrosis; Glucose Intolerance; Huntington Disease; Liver Cirrhosis; Obesity; Severe Acute Respiratory Syndrome; Adenomatous Polyposis Coli; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Cholangitis, Sclerosing; Cholestasis; Colorectal Neoplasms; Diabetes Mellitus; Heart Failure; Hepatitis D; Inflammation; Jaundice, Obstructive; Non-alcoholic Fatty Liver Disease; Parkinson Disease; Pregnancy; Cholelithiasis; Cholestasis, Intrahepatic; Diabetes, Gestational; Diabetes Mellitus, Type 2; Hepatitis C, Chronic; Liver Diseases; Liver Cirrhosis, Biliary

Bile acid receptor FXR agonist


Small molecule Approved Unknown Unknown Brain Neoplasms; Cognitive Dysfunction; Colorectal Neoplasms; Diabetes Mellitus, Type 1; Dysthymic Disorder; Wounds and Injuries; Cocaine-Related Disorders; Epilepsy; Gastroesophageal Reflux; Hypertension, Pulmonary; Ischemic Stroke; Marijuana Abuse; Multiple Sclerosis, Chronic Progressive; Multiple System Atrophy; Obesity; Panic Disorder; Sciatica; Anxiety; Autistic Disorder; Bipolar Disorder; Cerebral Hemorrhage; Dementia; Depressive Disorder; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Enuresis; Fibromyalgia; Influenza, Human; Obsessive-Compulsive Disorder; Phobia, Social; Schizophrenia; Severe Acute Respiratory Syndrome; Stress Disorders, Post-Traumatic; Stroke; Tobacco Use Disorder Unknown

Small molecule

Approved

Unknown

Brain Neoplasms; Cognitive Dysfunction; Colorectal Neoplasms; Diabetes Mellitus, Type 1; Dysthymic Disorder; Wounds and Injuries; Cocaine-Related Disorders; Epilepsy; Gastroesophageal Reflux; Hypertension, Pulmonary; Ischemic Stroke; Marijuana Abuse; Multiple Sclerosis, Chronic Progressive; Multiple System Atrophy; Obesity; Panic Disorder; Sciatica; Anxiety; Autistic Disorder; Bipolar Disorder; Cerebral Hemorrhage; Dementia; Depressive Disorder; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Enuresis; Fibromyalgia; Influenza, Human; Obsessive-Compulsive Disorder; Phobia, Social; Schizophrenia; Severe Acute Respiratory Syndrome; Stress Disorders, Post-Traumatic; Stroke; Tobacco Use Disorder

Unknown


Small molecule Approved OTHER ORAL Unknown Cyclooxygenase-2 inhibitor


Small molecule Approved OTHER ORAL Chemical and Drug Induced Liver Injury; Cystinuria; Subarachnoid Hemorrhage Reducing agent


Small molecule Approved OTHER INJECTION Cicatrix; Cardiomyopathy, Dilated; Hypertension Angiotensin-converting enzyme inhibitor


Small molecule Approved Unknown Unknown Substance-Related Disorders; Cocaine-Related Disorders; Parkinson Disease Unknown


Small molecule Approved OTHER TOPICAL Tinea; Tinea Pedis Cytochrome P450 51 inhibitor


Small molecule Approved OTHER ORAL Abortion, Incomplete; Infections; Clostridium Infections; Muscle Cramp; Non-alcoholic Fatty Liver Disease; Premature Birth; Abortion, Spontaneous; Leiomyoma; Menorrhagia; Myoma; Obesity; Pain; Postpartum Hemorrhage; Pre-Eclampsia; Pregnancy; Spondylitis, Ankylosing; Uterine Diseases; Duodenal Ulcer; Gastroesophageal Reflux; Hemorrhage; Osteoarthritis; Peptic Ulcer; Stomach Ulcer Prostanoid EP3 receptor agonist

Small molecule

Approved

OTHER

ORAL

Abortion, Incomplete; Infections; Clostridium Infections; Muscle Cramp; Non-alcoholic Fatty Liver Disease; Premature Birth; Abortion, Spontaneous; Leiomyoma; Menorrhagia; Myoma; Obesity; Pain; Postpartum Hemorrhage; Pre-Eclampsia; Pregnancy; Spondylitis, Ankylosing; Uterine Diseases; Duodenal Ulcer; Gastroesophageal Reflux; Hemorrhage; Osteoarthritis; Peptic Ulcer; Stomach Ulcer

Prostanoid EP3 receptor agonist


Small molecule Approved Unknown Unknown Cardiovascular Diseases; Glaucoma Unknown


Small molecule Approved Unknown Unknown Hypersensitivity Histamine H1 receptor antagonist


Small molecule Approved Unknown Unknown Unknown Bacterial dihydrofolate reductase inhibitor


Small molecule Approved OTHER INJECTION Neoplasms Diagnostic agent


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved OTHER INJECTION Esophageal and Gastric Varices Calcium chelating agent


Small molecule Approved OTHER INJECTION Unknown Unknown


Small molecule Approved Unknown Unknown Bacterial Infections Unknown


Small molecule Approved Unknown Unknown Gastritis; Gastroparesis; Duodenal Ulcer; Esophagitis; Gastroesophageal Reflux; Heartburn; Peptic Ulcer Histamine H2 receptor antagonist

Small molecule

Approved

OTHER; UROLOGY AND KIDNEY

INJECTION; INTRAVENOUS; ORAL

Adenocarcinoma; Blastic Plasmacytoid Dendritic Cell Neoplasm; Ganglioneuroblastoma; Kidney Neoplasms; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Muscular Diseases; Myasthenia Gravis; Myelodysplastic Syndromes; Neoplasm Metastasis; Obesity; Osteosarcoma; Primary Myelofibrosis; Stiff-Person Syndrome; Vasculitis; Acute Kidney Injury; Anemia, Aplastic; Anemia, Sickle Cell; Burkitt Lymphoma; Carcinoma, Hepatocellular; Central Nervous System Neoplasms; Crohn Disease; Hematologic Neoplasms; Hodgkin Disease; Leukemia, Lymphocytic, Chronic, B-Cell; Lupus Erythematosus, Systemic; Lymphoma, B-Cell; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Melanoma; Multiple Myeloma; Multiple Sclerosis; Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuromyelitis Optica; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency, Chronic; Retinoblastoma; Sarcoma, Ewing; Testicular Neoplasms; Brain Neoplasms; Breast Neoplasms; Ependymoma; Leukemia; Leukemia, Lymphoid; Lung Neoplasms; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Medulloblastoma; Multiple Sclerosis, Relapsing-Remitting; Neuroblastoma; Sarcoma; Scleroderma, Systemic; Thrombocytopenia

Unknown


Small molecule Approved Unknown Unknown Brain Neoplasms; Coronary Disease; Aortic Aneurysm, Thoracic; Stroke; Subarachnoid Hemorrhage; Hypertension; Muscle Cramp; Pre-Eclampsia; Cardiovascular Diseases Unknown

Small molecule

Approved

OTHER

INJECTION

Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Neoplasm Metastasis; Neoplasms, Plasma Cell; Breast Neoplasms; Burkitt Lymphoma; Leukemia, Myeloid, Acute; Lymphoma, AIDS-Related; Lymphoma, B-Cell; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Nasopharyngeal Neoplasms; Pancreatic Neoplasms; Penile Neoplasms; Peritoneal Neoplasms; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Urethral Neoplasms; Urinary Bladder Neoplasms; Uterine Neoplasms; Wilms Tumor; Carcinoma; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Dermatofibrosarcoma; Endometrial Neoplasms; Fallopian Tube Neoplasms; Fibrosarcoma; Hemangiosarcoma; Histiocytoma; Hodgkin Disease; Kidney Neoplasms; Leiomyosarcoma; Leukemia; Leukemia, Biphenotypic, Acute; Liposarcoma; Lung Neoplasms; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Mediastinal Neoplasms; Neoplasms, Germ Cell and Embryonal; Neurilemmoma; Neuroblastoma; Osteosarcoma; Ovarian Neoplasms; Pheochromocytoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Retroviridae Infections; Rhabdomyosarcoma; Sarcoma; Sarcoma, Alveolar Soft Part; Sarcoma, Ewing; Sarcoma, Synovial; Small Cell Lung Carcinoma; Teratoma; Uterine Cervical Neoplasms; Neoplasms; Testicular Neoplasms

DNA inhibitor