DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 6532


Small molecule Approved CARDIOVASCULAR; OTHER ORAL Inflammation; Asthma; Leukemia, Myeloid, Acute; Metabolic Diseases; Porokeratosis; Stroke; Arthritis, Rheumatoid; Breast Neoplasms; Carotid Stenosis; Cognitive Dysfunction; Fragile X Syndrome; Heart Diseases; HIV Infections; Intracranial Arteriosclerosis; Intracranial Arteriovenous Malformations; Learning Disabilities; Melanoma; Neurofibromatosis 1; Ovarian Neoplasms; Parkinson Disease; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Rett Syndrome; Xanthomatosis, Cerebrotendinous; Intermittent Claudication; Lipid Metabolism Disorders; Myocardial Ischemia; Atherosclerosis; Cardiovascular Diseases; Coronary Artery Disease; Coronary Disease; Hypercholesterolemia; Hypothyroidism HMG-CoA reductase inhibitor

Small molecule

Approved

CARDIOVASCULAR; OTHER

ORAL

Inflammation; Asthma; Leukemia, Myeloid, Acute; Metabolic Diseases; Porokeratosis; Stroke; Arthritis, Rheumatoid; Breast Neoplasms; Carotid Stenosis; Cognitive Dysfunction; Fragile X Syndrome; Heart Diseases; HIV Infections; Intracranial Arteriosclerosis; Intracranial Arteriovenous Malformations; Learning Disabilities; Melanoma; Neurofibromatosis 1; Ovarian Neoplasms; Parkinson Disease; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Rett Syndrome; Xanthomatosis, Cerebrotendinous; Intermittent Claudication; Lipid Metabolism Disorders; Myocardial Ischemia; Atherosclerosis; Cardiovascular Diseases; Coronary Artery Disease; Coronary Disease; Hypercholesterolemia; Hypothyroidism

HMG-CoA reductase inhibitor


Small molecule Approved Unknown Unknown Non-alcoholic Fatty Liver Disease Unknown


Small molecule Approved Unknown Unknown Glaucoma Unknown


Small molecule Approved GASTROINTESTINAL; OTHER ORAL; RECTAL Berylliosis; HIV Infections; Malnutrition; Adenoma; Colitis; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Diverticulum, Colon; Colitis, Collagenous; Colitis, Lymphocytic; Crohn Disease; Diverticular Diseases; Diverticulitis; Irritable Bowel Syndrome; Colitis, Ulcerative; Proctitis Arachidonate 5-lipoxygenase inhibitor

Small molecule

Approved

GASTROINTESTINAL; OTHER

ORAL; RECTAL

Berylliosis; HIV Infections; Malnutrition; Adenoma; Colitis; Colorectal Neoplasms; Colorectal Neoplasms, Hereditary Nonpolyposis; Diverticulum, Colon; Colitis, Collagenous; Colitis, Lymphocytic; Crohn Disease; Diverticular Diseases; Diverticulitis; Irritable Bowel Syndrome; Colitis, Ulcerative; Proctitis

Arachidonate 5-lipoxygenase inhibitor


Small molecule Approved Unknown Unknown Unknown Opioid receptors; mu/kappa/delta agonist


Small molecule Approved Unknown Unknown Dysuria; Pain; Urinary Retention Unknown


Small molecule Approved OTHER ORAL Unknown Norepinephrine transporter releasing agent


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved Unknown Unknown Cardiovascular Diseases Unknown


Small molecule Approved OTHER VAGINAL Vaginitis; Candidiasis, Vulvovaginal Cytochrome P450 51 inhibitor


Small molecule Approved Unknown Unknown Cognitive Dysfunction; Diabetes Mellitus, Type 1; Severe Acute Respiratory Syndrome; Wounds and Injuries; Dysthymic Disorder; Cocaine-Related Disorders; Epilepsy; Gastroesophageal Reflux; Hypertension, Pulmonary; Ischemic Stroke; Marijuana Abuse; Multiple Sclerosis, Chronic Progressive; Multiple System Atrophy; Obesity; Panic Disorder; Sciatica; Anxiety; Autistic Disorder; Bipolar Disorder; Cerebral Hemorrhage; Dementia; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Enuresis; Fibromyalgia; Obsessive-Compulsive Disorder; Phobia, Social; Schizophrenia; Stress Disorders, Post-Traumatic; Stroke; Tobacco Use Disorder; Depressive Disorder Unknown

Small molecule

Approved

Unknown

Cognitive Dysfunction; Diabetes Mellitus, Type 1; Severe Acute Respiratory Syndrome; Wounds and Injuries; Dysthymic Disorder; Cocaine-Related Disorders; Epilepsy; Gastroesophageal Reflux; Hypertension, Pulmonary; Ischemic Stroke; Marijuana Abuse; Multiple Sclerosis, Chronic Progressive; Multiple System Atrophy; Obesity; Panic Disorder; Sciatica; Anxiety; Autistic Disorder; Bipolar Disorder; Cerebral Hemorrhage; Dementia; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Enuresis; Fibromyalgia; Obsessive-Compulsive Disorder; Phobia, Social; Schizophrenia; Stress Disorders, Post-Traumatic; Stroke; Tobacco Use Disorder; Depressive Disorder

Unknown


Small molecule Approved Unknown Unknown Glioma; Sarcoma; Breast Neoplasms; Granuloma, Lethal Midline; Leukemia, Lymphoid; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Multiple Sclerosis; Leukemia, Myeloid, Acute; Lymphoma, T-Cell, Peripheral; Neoplasms Unknown


Small molecule Approved Unknown Unknown Parkinson Disease; Carotid Stenosis; Atherosclerosis; Coronary Disease; Diabetes Mellitus, Type 2; Hypercholesterolemia; Hypertension; Prostatic Hyperplasia Unknown


Small molecule Approved OTHER ORAL Glucose Intolerance; Huntington Disease; Liver Cirrhosis; Obesity; Adenomatous Polyposis Coli; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Cholangitis, Sclerosing; Cholestasis; Colorectal Neoplasms; Diabetes Mellitus, Type 2; Heart Failure; Inflammation; Jaundice, Obstructive; Non-alcoholic Fatty Liver Disease; Parkinson Disease; Pregnancy; Cholelithiasis; Cholestasis, Intrahepatic; Hepatitis C, Chronic; Liver Diseases; Liver Cirrhosis, Biliary Bile acid receptor FXR agonist

Small molecule

Approved

OTHER

ORAL

Glucose Intolerance; Huntington Disease; Liver Cirrhosis; Obesity; Adenomatous Polyposis Coli; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Cholangitis, Sclerosing; Cholestasis; Colorectal Neoplasms; Diabetes Mellitus, Type 2; Heart Failure; Inflammation; Jaundice, Obstructive; Non-alcoholic Fatty Liver Disease; Parkinson Disease; Pregnancy; Cholelithiasis; Cholestasis, Intrahepatic; Hepatitis C, Chronic; Liver Diseases; Liver Cirrhosis, Biliary

Bile acid receptor FXR agonist


Small molecule Approved OTHER IMPLANTATION; INHALATION; NASAL; TOPICAL Hypersensitivity; Spinal Cord Injuries; Anemia, Sickle Cell; Dermatitis, Atopic; Eosinophilic Esophagitis; Pemphigoid, Bullous; Psoriasis; Breast Neoplasms; Hypertrophy; Otitis Media with Effusion; Pulmonary Disease, Chronic Obstructive; Rhinitis, Allergic, Perennial; Severe Acute Respiratory Syndrome; Sinusitis; Sleep Apnea, Obstructive; Asthma; Lung Diseases, Obstructive; Nasal Obstruction; Nasal Polyps; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal; Skin Diseases Glucocorticoid receptor agonist

Small molecule

Approved

OTHER

IMPLANTATION; INHALATION; NASAL; TOPICAL

Hypersensitivity; Spinal Cord Injuries; Anemia, Sickle Cell; Dermatitis, Atopic; Eosinophilic Esophagitis; Pemphigoid, Bullous; Psoriasis; Breast Neoplasms; Hypertrophy; Otitis Media with Effusion; Pulmonary Disease, Chronic Obstructive; Rhinitis, Allergic, Perennial; Severe Acute Respiratory Syndrome; Sinusitis; Sleep Apnea, Obstructive; Asthma; Lung Diseases, Obstructive; Nasal Obstruction; Nasal Polyps; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal; Skin Diseases

Glucocorticoid receptor agonist


Small molecule Approved Unknown Unknown Rheumatic Diseases Cyclooxygenase inhibitor


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved Unknown Unknown Bacterial Infections Unknown


Small molecule Unknown Unknown Unknown Gastritis; Gastroparesis; Duodenal Ulcer; Esophagitis; Gastroesophageal Reflux; Heartburn; Peptic Ulcer Histamine H2 receptor antagonist


Small molecule Approved Unknown Unknown Cardiovascular Diseases; Glaucoma Unknown


Small molecule Approved Unknown Unknown Unknown Bacterial dihydrofolate reductase inhibitor


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved OTHER ORAL Chemical and Drug Induced Liver Injury; Cystinuria; Subarachnoid Hemorrhage Reducing agent


Small molecule Approved OTHER TOPICAL Tinea; Tinea Pedis Cytochrome P450 51 inhibitor


Small molecule Approved Unknown Unknown Coronary Disease; Brain Neoplasms; Aortic Aneurysm, Thoracic; Stroke; Subarachnoid Hemorrhage; Hypertension; Muscle Cramp; Pre-Eclampsia; Cardiovascular Diseases Unknown

Small molecule

Approved

OTHER

INJECTION

Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Neoplasm Metastasis; Breast Neoplasms; Burkitt Lymphoma; Leukemia, Myeloid, Acute; Lymphoma, AIDS-Related; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Nasopharyngeal Neoplasms; Pancreatic Neoplasms; Penile Neoplasms; Peritoneal Neoplasms; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Urethral Neoplasms; Urinary Bladder Neoplasms; Uterine Neoplasms; Wilms Tumor; Carcinoma; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Dermatofibrosarcoma; Endometrial Neoplasms; Fallopian Tube Neoplasms; Fibrosarcoma; Hemangiopericytoma; Hemangiosarcoma; Histiocytoma; Hodgkin Disease; Kidney Neoplasms; Leiomyosarcoma; Leukemia; Leukemia, Biphenotypic, Acute; Liposarcoma; Lung Neoplasms; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Mediastinal Neoplasms; Mesenchymoma; Neoplasms, Germ Cell and Embryonal; Neurilemmoma; Neuroblastoma; Osteosarcoma; Ovarian Neoplasms; Pheochromocytoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retroviridae Infections; Rhabdomyosarcoma; Sarcoma; Sarcoma, Alveolar Soft Part; Sarcoma, Ewing; Sarcoma, Synovial; Small Cell Lung Carcinoma; Teratoma; Uterine Cervical Neoplasms; Neoplasms; Testicular Neoplasms

DNA inhibitor


Small molecule Approved Unknown Unknown Cocaine-Related Disorders; Parkinson Disease Unknown


Small molecule Approved OTHER INJECTION Unknown Diagnostic agent


Small molecule Approved Unknown Unknown Hypersensitivity Histamine H1 receptor antagonist


Small molecule Approved OTHER INJECTION Unknown Unknown

Small molecule

Approved

OTHER; UROLOGY AND KIDNEY

INJECTION; INTRAVENOUS; ORAL

Kidney Neoplasms; Leukemia, Myeloid, Acute; Muscular Diseases; Myasthenia Gravis; Myelodysplastic Syndromes; Neoplasm Metastasis; Obesity; Osteosarcoma; Primary Myelofibrosis; Stiff-Person Syndrome; Vasculitis; Acute Kidney Injury; Anemia, Aplastic; Anemia, Sickle Cell; Burkitt Lymphoma; Carcinoma, Hepatocellular; Crohn Disease; Hematologic Neoplasms; Hodgkin Disease; Leukemia, Lymphocytic, Chronic, B-Cell; Lupus Erythematosus, Systemic; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Melanoma; Multiple Myeloma; Multiple Sclerosis; Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuromyelitis Optica; Renal Insufficiency, Chronic; Retinoblastoma; Sarcoma, Ewing; Testicular Neoplasms; Brain Neoplasms; Breast Neoplasms; Leukemia; Lung Neoplasms; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Multiple Sclerosis, Relapsing-Remitting; Neuroblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma; Scleroderma, Systemic; Thrombocytopenia

Unknown


Small molecule Approved OTHER INJECTION Esophageal and Gastric Varices Calcium chelating agent


Small molecule Approved Unknown Unknown Bacterial Infections Unknown

Small molecule

Approved

OTHER

ORAL

Infections; Abortion, Incomplete; Clostridium Infections; Muscle Cramp; Premature Birth; Abortion, Spontaneous; Leiomyoma; Menorrhagia; Obesity; Pain; Postpartum Hemorrhage; Pre-Eclampsia; Pregnancy; Spondylitis, Ankylosing; Uterine Diseases; Duodenal Ulcer; Gastroesophageal Reflux; Hemorrhage; Osteoarthritis; Peptic Ulcer; Stomach Ulcer

Prostanoid EP3 receptor agonist


Small molecule Approved CARDIOVASCULAR; OTHER ORAL Cerebrovascular Disorders; Schizophrenia; Intracranial Aneurysm; Cocaine-Related Disorders; Infertility; Neurilemmoma; Stroke; Subarachnoid Hemorrhage; Cardiovascular Diseases Mineralocorticoid receptor antagonist