DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 6532


Small molecule Approved Unknown Unknown Amyotrophic Lateral Sclerosis; Insulin Resistance; Hepatitis D; Leukemia, Lymphocytic, Chronic, B-Cell; Weight Gain; Acquired Immunodeficiency Syndrome; Hepatitis B, Chronic; HIV Infections; Severe Acute Respiratory Syndrome; Virus Diseases Human immunodeficiency virus type 1 reverse transcriptase inhibitor


Small molecule Approved Unknown ORAL Alcoholism; Borderline Personality Disorder; Alzheimer Disease; Bipolar Disorder; Depressive Disorder; Mental Disorders; Psychomotor Agitation; Sleep Wake Disorders; Stress Disorders, Post-Traumatic; Depressive Disorder, Major; Psychotic Disorders; Schizophrenia Dopamine D2 receptor partial agonist


Small molecule Approved Unknown ORAL Breast Diseases; Carcinoma, Ductal; Carcinoma, Pancreatic Ductal; Glioblastoma; Head and Neck Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Histiocytoma, Malignant Fibrous; Kidney Diseases; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma, Non-Hodgkin; Multiple Myeloma; Pancreatic Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Adenocarcinoma; Carcinoma, Hepatocellular; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Chordoma; Colonic Neoplasms; Endometrial Neoplasms; Esophageal Neoplasms; Liposarcoma; Lymphoma; Lymphoma, Mantle-Cell; Melanoma; Nasopharyngeal Carcinoma; Neuroendocrine Tumors; Oligodendroglioma; Osteosarcoma; Ovarian Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoma, Ewing; Severe Acute Respiratory Syndrome; Thymus Neoplasms; Urinary Bladder Neoplasms; Carcinoma, Squamous Cell; Sarcoma; Breast Neoplasms; Neoplasms CDK6/cyclin D1 inhibitor

Small molecule

Approved

Unknown

ORAL

Breast Diseases; Carcinoma, Ductal; Carcinoma, Pancreatic Ductal; Glioblastoma; Head and Neck Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Histiocytoma, Malignant Fibrous; Kidney Diseases; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma, Non-Hodgkin; Multiple Myeloma; Pancreatic Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Adenocarcinoma; Carcinoma, Hepatocellular; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Chordoma; Colonic Neoplasms; Endometrial Neoplasms; Esophageal Neoplasms; Liposarcoma; Lymphoma; Lymphoma, Mantle-Cell; Melanoma; Nasopharyngeal Carcinoma; Neuroendocrine Tumors; Oligodendroglioma; Osteosarcoma; Ovarian Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoma, Ewing; Severe Acute Respiratory Syndrome; Thymus Neoplasms; Urinary Bladder Neoplasms; Carcinoma, Squamous Cell; Sarcoma; Breast Neoplasms; Neoplasms

CDK6/cyclin D1 inhibitor


Small molecule Approved Unknown Unknown Hepatitis C; Hepatitis C, Chronic Nonstructural protein 5A inhibitor


Small molecule Approved Unknown Unknown Virus Diseases Unknown


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved Unknown Unknown Pain; Blood Coagulation Disorders; Cognitive Dysfunction; Hemorrhage; Hypotension; Pre-Eclampsia; Cardiovascular Diseases; Nasal Obstruction; Obesity Unknown


Small molecule Approved Unknown INTRAVENOUS Glucosephosphate Dehydrogenase Deficiency; Jaundice; Sepsis; Abscess; Malaria; Malaria, Falciparum; Severe Acute Respiratory Syndrome; Stress Disorders, Post-Traumatic; Tooth Diseases; Wounds and Injuries; Bipolar Disorder; Dysuria; Shock, Septic; Urinary Tract Infections Reducing agent


Small molecule Approved Unknown Unknown Carcinoma, Non-Small-Cell Lung; Small Cell Lung Carcinoma; Biliary Tract Neoplasms; Breast Neoplasms; Carcinoma, Pancreatic Ductal; Endometrial Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Leiomyosarcoma; Mesothelioma; Pancreatic Neoplasms; Retroviridae Infections; Stomach Neoplasms; Uterine Cervical Neoplasms; Fallopian Tube Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Neoplasms PARP 1, 2 and 3 inhibitor

Small molecule

Approved

Unknown

Carcinoma, Non-Small-Cell Lung; Small Cell Lung Carcinoma; Biliary Tract Neoplasms; Breast Neoplasms; Carcinoma, Pancreatic Ductal; Endometrial Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Leiomyosarcoma; Mesothelioma; Pancreatic Neoplasms; Retroviridae Infections; Stomach Neoplasms; Uterine Cervical Neoplasms; Fallopian Tube Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Neoplasms

PARP 1, 2 and 3 inhibitor


Small molecule Approved Unknown INTRAVENOUS; ORAL Brain Neoplasms; Spinal Cord Injuries; Neuralgia, Postherpetic; Epilepsy, Absence; Unverricht-Lundborg Syndrome; Epilepsy; Seizures Synaptic vesicle glycoprotein 2A modulator


Small molecule Approved Unknown ORAL Amyloidosis, Familial; Burkitt Lymphoma; Carcinoma, Non-Small-Cell Lung; HIV Infections; Idiopathic Pulmonary Fibrosis; Kidney Diseases; Leukemia, Myelomonocytic, Chronic; Leukemia, Prolymphocytic; Lymphohistiocytosis, Hemophagocytic; Lymphoma, T-Cell, Cutaneous; Prostatic Neoplasms; Small Cell Lung Carcinoma; Amyloidosis; Blastic Plasmacytoid Dendritic Cell Neoplasm; Breast Neoplasms; Hematologic Neoplasms; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Prolymphocytic, T-Cell; Leukemia, Promyelocytic, Acute; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Myeloproliferative Disorders; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Waldenstrom Macroglobulinemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma, Mantle-Cell; Multiple Myeloma; Myelodysplastic Syndromes; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasms Apoptosis regulator Bcl-2 inhibitor

Small molecule

Approved

Unknown

ORAL

Amyloidosis, Familial; Burkitt Lymphoma; Carcinoma, Non-Small-Cell Lung; HIV Infections; Idiopathic Pulmonary Fibrosis; Kidney Diseases; Leukemia, Myelomonocytic, Chronic; Leukemia, Prolymphocytic; Lymphohistiocytosis, Hemophagocytic; Lymphoma, T-Cell, Cutaneous; Prostatic Neoplasms; Small Cell Lung Carcinoma; Amyloidosis; Blastic Plasmacytoid Dendritic Cell Neoplasm; Breast Neoplasms; Hematologic Neoplasms; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Prolymphocytic, T-Cell; Leukemia, Promyelocytic, Acute; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Myeloproliferative Disorders; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Waldenstrom Macroglobulinemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma, Mantle-Cell; Multiple Myeloma; Myelodysplastic Syndromes; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasms

Apoptosis regulator Bcl-2 inhibitor


Small molecule Approved Unknown Unknown Hepatitis, Viral, Human; Hepatitis C; Hepatitis C, Chronic; Virus Diseases Nonstructural protein 5A inhibitor


Small molecule Approved Unknown OPHTHALMIC Graft vs Host Disease; Conjunctivitis, Allergic; Dry Eye Syndromes; Eye Diseases Integrin alpha-L/beta-2 (LFA-1) antagonist


Small molecule Approved Unknown Unknown Tourette Syndrome; Parkinson Disease; Depressive Disorder, Major; Neurodegenerative Diseases; Schizophrenia; Psychotic Disorders Unknown


Small molecule Approved Unknown Unknown Carcinoma, Lobular; Glioma; Brain Neoplasms; Glioblastoma; Nasopharyngeal Carcinoma; Prostatic Neoplasms, Castration-Resistant; Paraganglioma; Prostatic Neoplasms; Radionuclide Imaging Diagnostic agent


Small molecule Approved Unknown ORAL Adenomatous Polyposis Coli; Cholestasis; Liver Diseases; Obesity; Pruritus; Barrett Esophagus; Cholangitis, Sclerosing; Hepatitis, Alcoholic; Lipodystrophy, Familial Partial; Non-alcoholic Fatty Liver Disease; Cholangitis; Liver Cirrhosis, Biliary Bile acid receptor FXR agonist


Small molecule Approved Unknown VAGINAL Diabetes Mellitus, Type 1; Sarcoma, Synovial; Crohn Disease; Depressive Disorder; Erectile Dysfunction; HIV Infections; Hot Flashes; Low Back Pain; Multiple Myeloma; Myotonic Dystrophy; Primary Ovarian Insufficiency; Stress Disorders, Post-Traumatic; Substance Withdrawal Syndrome; Addison Disease; Adrenal Insufficiency; Aging; Anorexia Nervosa; Breast Neoplasms; Genital Neoplasms, Female; Infertility; Lupus Erythematosus, Systemic; Malaria; Menopause; Sexual Dysfunction, Physiological; Skin Aging; Arthritis, Rheumatoid; Atrophic Vaginitis; Dysmenorrhea; Osteoarthritis; Pain Unknown

Small molecule

Approved

Unknown

VAGINAL

Diabetes Mellitus, Type 1; Sarcoma, Synovial; Crohn Disease; Depressive Disorder; Erectile Dysfunction; HIV Infections; Hot Flashes; Low Back Pain; Multiple Myeloma; Myotonic Dystrophy; Primary Ovarian Insufficiency; Stress Disorders, Post-Traumatic; Substance Withdrawal Syndrome; Addison Disease; Adrenal Insufficiency; Aging; Anorexia Nervosa; Breast Neoplasms; Genital Neoplasms, Female; Infertility; Lupus Erythematosus, Systemic; Malaria; Menopause; Sexual Dysfunction, Physiological; Skin Aging; Arthritis, Rheumatoid; Atrophic Vaginitis; Dysmenorrhea; Osteoarthritis; Pain

Unknown


Small molecule Approved Unknown TOPICAL Alopecia Areata; Dermatitis; Psoriasis; Scleroderma, Localized; Vitiligo; Dermatitis, Atopic; Eczema Phosphodiesterase 4 inhibitor


Small molecule Approved Unknown Unknown Glaucoma, Open-Angle; Corneal Edema; Fuchs' Endothelial Dystrophy; Glaucoma Unknown


Small molecule Approved Unknown Unknown Fallopian Tube Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Lung Neoplasms; Paraganglioma; Peritoneal Neoplasms; Rectal Neoplasms; Sarcoma, Ewing; Stomach Neoplasms; Urogenital Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Colorectal Neoplasms; Endometrial Neoplasms; Glioblastoma; Head and Neck Neoplasms; Lymphoma; Melanoma; Mesothelioma; Pancreatic Neoplasms; Penile Neoplasms; Prostatic Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Biliary Tract Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Hereditary Breast and Ovarian Cancer Syndrome; Ovarian Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Neoplasms Poly [ADP-ribose] polymerase-1 inhibitor

Small molecule

Approved

Unknown

Fallopian Tube Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Lung Neoplasms; Paraganglioma; Peritoneal Neoplasms; Rectal Neoplasms; Sarcoma, Ewing; Stomach Neoplasms; Urogenital Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Colorectal Neoplasms; Endometrial Neoplasms; Glioblastoma; Head and Neck Neoplasms; Lymphoma; Melanoma; Mesothelioma; Pancreatic Neoplasms; Penile Neoplasms; Prostatic Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Biliary Tract Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Hereditary Breast and Ovarian Cancer Syndrome; Ovarian Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Neoplasms

Poly [ADP-ribose] polymerase-1 inhibitor


Small molecule Approved Unknown INTRAVENOUS; ORAL Graft vs Host Disease; Pregnancy; Cytomegalovirus Infections; Infections; Virus Diseases DNA terminase inhibitor


Small molecule Approved Unknown Unknown Kidney Diseases; Liver Diseases; Renal Insufficiency, Chronic; Stress Disorders, Post-Traumatic; Hepatitis C; Hepatitis C, Chronic Nonstructural protein 5A inhibitor


Small molecule Approved Unknown Unknown Hepatitis C; Hepatitis C, Chronic Hepatitis C virus serine protease, NS3/NS4A inhibitor


Small molecule Approved Unknown Unknown Astrocytoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colorectal Neoplasms; Diffuse Intrinsic Pontine Glioma; Glioblastoma; Glioma; Kidney Diseases; Lymphoma; Neuroblastoma; Paraganglioma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Myelofibrosis; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rhabdoid Tumor; Carcinoma; Carcinoma, Hepatocellular; Fallopian Tube Neoplasms; Liposarcoma; Melanoma; Neoplasms; Neuroendocrine Tumors; Ovarian Neoplasms; Sarcoma; Teratoma; Thymus Neoplasms; Uterine Neoplasms; Breast Neoplasms Cyclin-dependent kinase 4 inhibitor

Small molecule

Approved

Unknown

Astrocytoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colorectal Neoplasms; Diffuse Intrinsic Pontine Glioma; Glioblastoma; Glioma; Kidney Diseases; Lymphoma; Neuroblastoma; Paraganglioma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Myelofibrosis; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rhabdoid Tumor; Carcinoma; Carcinoma, Hepatocellular; Fallopian Tube Neoplasms; Liposarcoma; Melanoma; Neoplasms; Neuroendocrine Tumors; Ovarian Neoplasms; Sarcoma; Teratoma; Thymus Neoplasms; Uterine Neoplasms; Breast Neoplasms

Cyclin-dependent kinase 4 inhibitor


Small molecule Approved Unknown Unknown Pancreatitis; Constipation Mu opioid receptor antagonist

Small molecule

Approved

Unknown

ORAL

Communicable Diseases; Glioblastoma; Leukemia; Leukemia, Prolymphocytic; Lymphoma; Multiple Myeloma; Arthritis, Rheumatoid; Bronchiolitis Obliterans Syndrome; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Food Hypersensitivity; Hematologic Neoplasms; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Ovarian Neoplasms; Pancreatic Neoplasms; Waldenstrom Macroglobulinemia; Lymphoma, Large B-Cell, Diffuse; Severe Acute Respiratory Syndrome; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Mantle-Cell; Neoplasms

Tyrosine-protein kinase BTK inhibitor


Small molecule Approved Unknown Unknown Tourette Syndrome; Trichotillomania; Huntington Disease; Movement Disorders; Schizophrenia Synaptic vesicular amine transporter inhibitor


Small molecule Approved Unknown ORAL Chagas Disease; Leishmaniasis; Trypanosomiasis Unknown


Small molecule Approved Unknown ORAL Heart Failure; Diabetes Mellitus; Diabetes Mellitus, Type 2; Mitral Valve Insufficiency Sodium/glucose cotransporter 2 inhibitor


Small molecule Approved Unknown ORAL Lymphoma, Large-Cell, Anaplastic; Carcinoma; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasms ALK tyrosine kinase receptor inhibitor


Small molecule Approved Unknown Unknown Liver Diseases; Biliary Tract Neoplasms; Malignant Carcinoid Syndrome; Neuroendocrine Tumors; Pancreatic Neoplasms; Carcinoid Heart Disease Tryptophan 5-hydroxylase inhibitor


Small molecule Approved Unknown Unknown Carcinoid Tumor; Diarrhea; Neuroendocrine Tumors Tryptophan 5-hydroxylase inhibitor


Small molecule Approved Unknown INTRAVENOUS; ORAL Community-Acquired Infections; Skin Diseases, Bacterial Bacterial DNA gyrase inhibitor

Small molecule

Approved

Unknown

ORAL

Carcinoma, Renal Cell; Colorectal Neoplasms; Cystadenocarcinoma, Serous; Diffuse Intrinsic Pontine Glioma; Glioma; Lymphoma; Lymphoma, Non-Hodgkin; Multiple Myeloma; Neoplasm Metastasis; Neuroblastoma; Neurofibromatosis 1; Osteosarcoma; Ovarian Neoplasms; Prostatic Neoplasms; Rhabdoid Tumor; Rhabdomyosarcoma; Sarcoma, Ewing; Sarcoma, Kaposi; Urinary Bladder Neoplasms; Biliary Tract Neoplasms; Brain Neoplasms; Breast Neoplasms, Male; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Endometrial Neoplasms; Genital Neoplasms, Female; Glioblastoma; Head and Neck Neoplasms; Hemangiosarcoma; Lung Neoplasms; Lymphoma, Mantle-Cell; Melanoma; Meningioma; Mesothelioma; Neuroendocrine Tumors; Oligodendroglioma; Paraganglioma; Prostatic Neoplasms, Castration-Resistant; Thyroid Neoplasms; Carcinoma, Non-Small-Cell Lung; Liposarcoma; Breast Neoplasms; Neoplasms

Cyclin-dependent kinase 4 inhibitor


Small molecule Approved Unknown Unknown Unknown Unknown