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Total: 6532
Small molecule
Approved
Unknown
TOPICAL
Wounds and Injuries; Impetigo
DNA gyrase inhibitor
Small molecule
Approved
Unknown
ORAL
Glioma; Urinary Bladder Neoplasms; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Colorectal Neoplasms; Diffuse Intrinsic Pontine Glioma; Lymphoma; Lymphoma, Non-Hodgkin; Multiple Myeloma; Neoplasm Metastasis; Neuroblastoma; Neurofibromatosis 1; Osteosarcoma; Pancreatic Neoplasms; Rhabdoid Tumor; Rhabdomyosarcoma; Sarcoma, Ewing; Sarcoma, Kaposi; Brain Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Endometrial Neoplasms; Genital Neoplasms, Female; Glioblastoma; Head and Neck Neoplasms; Lung Neoplasms; Lymphoma, Mantle-Cell; Melanoma; Mesothelioma; Oligodendroglioma; Prostatic Neoplasms, Castration-Resistant; Thyroid Neoplasms; Carcinoma, Non-Small-Cell Lung; Liposarcoma; Breast Neoplasms; Neoplasms
Cyclin-dependent kinase 4 inhibitor
Small molecule
Approved
Unknown
OPHTHALMIC
Glaucoma; Glaucoma, Open-Angle; Ocular Hypertension
Prostanoid FP receptor agonist
Small molecule
Approved
Unknown
ORAL
Communicable Diseases; Glioblastoma; Leukemia; Leukemia, Prolymphocytic; Multiple Myeloma; Neoplasms; Arthritis, Rheumatoid; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Graft vs Host Disease; Hematologic Neoplasms; Lymphoma; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Ovarian Neoplasms; Pancreatic Neoplasms; Waldenstrom Macroglobulinemia; Lymphoma, Large B-Cell, Diffuse; Severe Acute Respiratory Syndrome; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Mantle-Cell
Tyrosine-protein kinase BTK inhibitor
Small molecule
Approved
Unknown
Unknown
Hypersensitivity; Substance Withdrawal Syndrome; Cocaine-Related Disorders; Opioid-Related Disorders
Unknown
Small molecule
Approved
Unknown
Unknown
Hematologic Neoplasms; Liver Diseases; Multiple Myeloma; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; Leukemia; Neoplasms
Unknown
Small molecule
Approved
Unknown
Unknown
Dystonic Disorders; Cerebral Palsy; Movement Disorders; Tourette Syndrome; Chorea; Huntington Disease
Synaptic vesicular amine transporter inhibitor
Small molecule
Approved
Unknown
Unknown
Cachexia
Ghrelin receptor agonist
Small molecule
Approved
Unknown
INTRAVENOUS; ORAL
Cytomegalovirus Infections; Infections; Virus Diseases
DNA terminase inhibitor
Small molecule
Approved
Unknown
Unknown
Liver Diseases; Pneumonia; Gonorrhea; Infections; Pneumonia, Bacterial; Bacterial Infections
Unknown
Small molecule
Approved
Unknown
ORAL
Kidney Diseases; Liver Diseases; Aspergillosis, Allergic Bronchopulmonary; Muscular Dystrophies, Limb-Girdle; Muscular Dystrophies; Muscular Dystrophy, Duchenne
Glucocorticoid receptor agonist
Small molecule
Approved
Unknown
INTRAVENOUS
Kidney Diseases; Liver Diseases; Brain Injuries; Cerebral Hemorrhage; Stroke; Ischemic Stroke; Amyotrophic Lateral Sclerosis
Unknown
Small molecule
Approved
Unknown
ORAL
Liver Diseases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Rectal Neoplasms; Blast Crisis; Myelodysplastic Syndromes; Leukemia; Leukemia, Mast-Cell; Leukemia, Myeloid, Acute; Mastocytosis; Mastocytosis, Systemic; Neoplasms
Platelet-derived growth factor receptor inhibitor
Small molecule
Approved
Unknown
INTRAVENOUS; ORAL
Skin Diseases, Bacterial
Bacterial DNA gyrase inhibitor
Small molecule
Approved
Unknown
Unknown
Glaucoma, Open-Angle; Corneal Edema; Fuchs' Endothelial Dystrophy; Glaucoma
Unknown
Small molecule
Approved
Unknown
Unknown
Fallopian Tube Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Lung Neoplasms; Peritoneal Neoplasms; Rectal Neoplasms; Sarcoma, Ewing; Stomach Neoplasms; Urogenital Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Colorectal Neoplasms; Endometrial Neoplasms; Glioblastoma; Head and Neck Neoplasms; Lymphoma; Melanoma; Mesothelioma; Pancreatic Neoplasms; Prostatic Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Hereditary Breast and Ovarian Cancer Syndrome; Ovarian Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Neoplasms
Poly [ADP-ribose] polymerase-1 inhibitor
Small molecule
Approved
Unknown
Unknown
Carcinoma; Colorectal Neoplasms; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Ovarian Neoplasms; Carcinoma, Non-Small-Cell Lung; Glioblastoma; Hemangiosarcoma; Prostatic Neoplasms; Breast Neoplasms; Neoplasms
Epidermal growth factor receptor erbB1 inhibitor
Small molecule
Approved
Unknown
ORAL
Colorectal Neoplasms; Liver Diseases; Mouth Neoplasms; Neoplasm Metastasis; Brain Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Glioblastoma; Head and Neck Neoplasms; Penile Neoplasms; Carcinoma, Non-Small-Cell Lung; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasms
Epidermal growth factor receptor erbB1 inhibitor
Small molecule
Approved
Unknown
ORAL
Irritable Bowel Syndrome; Diarrhea; Eye Infections; Tuberculosis
Unknown
Small molecule
Approved
Unknown
Unknown
Liver Diseases; Renal Insufficiency, Chronic; Infections; Urinary Tract Infections; Bacterial Infections
Unknown
Small molecule
Approved
Unknown
Unknown
Malaria, Falciparum; Severe Acute Respiratory Syndrome; Malaria, Vivax; Malaria
Unknown
Small molecule
Approved
Unknown
Unknown
Diarrhea
DNA-directed RNA polymerase inhibitor
Small molecule
Approved
Unknown
ORAL
Liver Diseases; Salivary Gland Neoplasms; Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant
Androgen Receptor antagonist
Small molecule
Approved
Unknown
ORAL
Anorexia Nervosa; Cognitive Dysfunction; Crohn Disease; Cystitis, Interstitial; Essential Tremor; Heart Failure; Lung Neoplasms; Prostatic Neoplasms; Radiculopathy; Status Epilepticus; Sturge-Weber Syndrome; Toothache; Alcoholism; Anxiety; Arthritis, Psoriatic; Autistic Disorder; Bipolar Disorder; Child Development Disorders, Pervasive; Chronic Pain; Cocaine-Related Disorders; Colitis, Ulcerative; Diabetic Neuropathies; Epilepsy, Absence; Fatty Liver; Graft vs Host Disease; Hepatitis, Autoimmune; HIV Infections; Huntington Disease; Intellectual Disability; Marijuana Abuse; Migraine Disorders; Neoplasms; Neuralgia; Obsessive-Compulsive Disorder; Opioid-Related Disorders; Parkinson Disease; Peripheral Nervous System Diseases; Prader-Willi Syndrome; Schizophrenia; Severe Acute Respiratory Syndrome; Stress Disorders, Post-Traumatic; Tobacco Use Disorder; Amyotrophic Lateral Sclerosis; Fibromyalgia; Fragile X Syndrome; Osteoarthritis; Pain; Psychotic Disorders; Rett Syndrome; Spasms, Infantile; Epilepsies, Myoclonic; Epilepsy; Lennox Gastaut Syndrome; Seizures; Tuberous Sclerosis
Cannabinoid CB1 receptor negative allosteric modulator
Small molecule
Approved
Unknown
Unknown
Fabry Disease
Alpha-galactosidase A stabiliser
Small molecule
Approved
Unknown
Unknown
Pneumonia; Pyelonephritis; Urinary Tract Infections; Pneumonia, Bacterial; Bacterial Infections
Unknown
Small molecule
Approved
Unknown
Unknown
Glioblastoma; Graft vs Host Disease; Myelodysplastic Syndromes; Leukemia, Myeloid, Acute; Sarcoma; Neoplasms
Smoothened homolog antagonist
Small molecule
Approved
Unknown
Unknown
Liver Diseases; Deglutition Disorders; Ileus; Irritable Bowel Syndrome; Intestinal Pseudo-Obstruction; Constipation
Serotonin 4 (5-HT4) receptor agonist
Small molecule
Approved
Unknown
Unknown
HIV Infections
Human immunodeficiency virus type 1 integrase inhibitor
Small molecule
Approved
Unknown
Unknown
Leukemia; Leukemia, Myeloid, Acute; Pancreatic Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Endometrial Neoplasms; Glioblastoma; Hemangiosarcoma; Hereditary Breast and Ovarian Cancer Syndrome; Prostatic Neoplasms; Small Cell Lung Carcinoma; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Breast Neoplasms; Ovarian Neoplasms; Prostatic Neoplasms, Castration-Resistant; Neoplasms
Poly [ADP-ribose] polymerase-1 inhibitor
Small molecule
Approved
Unknown
ORAL
Liver Diseases; Thrombocytopenia
Thrombopoietin receptor agonist
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Carcinoid Tumor; Neuroblastoma; Paraganglioma; Pheochromocytoma
Norepinephrine transporter substrate
Small molecule
Approved
Unknown
Unknown
Acquired Immunodeficiency Syndrome; HIV Infections
Human immunodeficiency virus type 1 integrase inhibitor
Small molecule
Unknown
Unknown
Unknown
Unknown
Progesterone receptor agonist