DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 1496


Small molecule Approved IMMUNE SYSTEM; OTHER; RESPIRATORY ORAL Anovulation; Depressive Disorder, Major; HIV Infections; Neoplasm Metastasis; Neoplasms; Osteomyelitis; Parkinson Disease; Prostatic Neoplasms, Castration-Resistant; Venous Thromboembolism; Buruli Ulcer; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cystic Fibrosis; Disorders of Excessive Somnolence; Idiopathic Hypersomnia; Leukemia, Lymphocytic, Chronic, B-Cell; Lung Diseases; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Narcolepsy; Periodontitis; Pseudomyxoma Peritonei; Toxoplasmosis, Cerebral; Asthma; Bronchiolitis Obliterans; Bronchopulmonary Dysplasia; Crohn Disease; Gastritis; Heart Diseases; Helicobacter Infections; Hemorrhage; Lymphoma, Non-Hodgkin; Multiple Myeloma; Mycobacterium avium-intracellulare Infection; Pneumonia, Bacterial; Sepsis; Shock, Septic; Stomach Neoplasms; Stomach Ulcer; Tuberculosis; Bacterial Infections; Bronchitis, Chronic; Duodenal Ulcer; Infections; Maxillary Sinusitis; Otitis Media; Pharyngitis; Pneumonia; Sinusitis; Tonsillitis Bacterial 70S ribosome inhibitor

Small molecule

Approved

IMMUNE SYSTEM; OTHER; RESPIRATORY

ORAL

Anovulation; Depressive Disorder, Major; HIV Infections; Neoplasm Metastasis; Neoplasms; Osteomyelitis; Parkinson Disease; Prostatic Neoplasms, Castration-Resistant; Venous Thromboembolism; Buruli Ulcer; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cystic Fibrosis; Disorders of Excessive Somnolence; Idiopathic Hypersomnia; Leukemia, Lymphocytic, Chronic, B-Cell; Lung Diseases; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Narcolepsy; Periodontitis; Pseudomyxoma Peritonei; Toxoplasmosis, Cerebral; Asthma; Bronchiolitis Obliterans; Bronchopulmonary Dysplasia; Crohn Disease; Gastritis; Heart Diseases; Helicobacter Infections; Hemorrhage; Lymphoma, Non-Hodgkin; Multiple Myeloma; Mycobacterium avium-intracellulare Infection; Pneumonia, Bacterial; Sepsis; Shock, Septic; Stomach Neoplasms; Stomach Ulcer; Tuberculosis; Bacterial Infections; Bronchitis, Chronic; Duodenal Ulcer; Infections; Maxillary Sinusitis; Otitis Media; Pharyngitis; Pneumonia; Sinusitis; Tonsillitis

Bacterial 70S ribosome inhibitor


Small molecule Approved EYE; IMMUNE SYSTEM; OTHER INJECTION; OPHTHALMIC; ORAL Anemia, Sickle Cell; Graves Ophthalmopathy; Hemorrhagic Fever, Ebola; Immune System Diseases; Obesity; Osteomyelitis; Respiratory Distress Syndrome; Sepsis; Toxoplasmosis, Cerebral; Communicable Diseases; Crohn Disease; Dysentery, Bacillary; Eye Diseases; Gastrointestinal Hemorrhage; Gastroparesis; Multiple Sclerosis; Neoplasms; Obsessive-Compulsive Disorder; Onchocerciasis; Periodontitis; Respiratory Syncytial Virus Infections; Sarcoidosis; Tuberculosis; Virus Diseases; Whooping Cough; Abdominal Pain; Acne Vulgaris; Arthritis, Reactive; Asthma; Blepharitis; Bronchial Diseases; Bronchiectasis; Bronchiolitis Obliterans; Bronchitis; Bronchopulmonary Dysplasia; Cardiovascular Diseases; Chlamydia Infections; Chronic Periodontitis; Conjunctivitis, Inclusion; Coronary Disease; Coronavirus Infections; Cough; Diarrhea; Digestive System Diseases; Fever; Gonorrhea; Heart Diseases; Inflammation; Lung Diseases; Malaria; Malaria, Falciparum; Malnutrition; Maxillary Sinusitis; Mycobacterium avium-intracellulare Infection; Mycobacterium Infections; Mycoses; Myocardial Infarction; Neonatal Sepsis; Otitis Media, Suppurative; Pneumonia, Viral; Pregnancy; Premature Birth; Respiratory Insufficiency; Severe Acute Respiratory Syndrome; Spotted Fever Group Rickettsiosis; Syphilis; Vomiting; Yaws; Bacterial Infections; Bronchitis, Chronic; Conjunctivitis, Bacterial; Cystic Fibrosis; Eye Infections; HIV Infections; Infections; Otitis Media; Pelvic Inflammatory Disease; Pharyngitis; Pneumonia; Pulmonary Disease, Chronic Obstructive; Sinusitis; Tonsillitis; Urethritis; Uterine Cervicitis Bacterial 70S ribosome inhibitor

Small molecule

Approved

EYE; IMMUNE SYSTEM; OTHER

INJECTION; OPHTHALMIC; ORAL

Anemia, Sickle Cell; Graves Ophthalmopathy; Hemorrhagic Fever, Ebola; Immune System Diseases; Obesity; Osteomyelitis; Respiratory Distress Syndrome; Sepsis; Toxoplasmosis, Cerebral; Communicable Diseases; Crohn Disease; Dysentery, Bacillary; Eye Diseases; Gastrointestinal Hemorrhage; Gastroparesis; Multiple Sclerosis; Neoplasms; Obsessive-Compulsive Disorder; Onchocerciasis; Periodontitis; Respiratory Syncytial Virus Infections; Sarcoidosis; Tuberculosis; Virus Diseases; Whooping Cough; Abdominal Pain; Acne Vulgaris; Arthritis, Reactive; Asthma; Blepharitis; Bronchial Diseases; Bronchiectasis; Bronchiolitis Obliterans; Bronchitis; Bronchopulmonary Dysplasia; Cardiovascular Diseases; Chlamydia Infections; Chronic Periodontitis; Conjunctivitis, Inclusion; Coronary Disease; Coronavirus Infections; Cough; Diarrhea; Digestive System Diseases; Fever; Gonorrhea; Heart Diseases; Inflammation; Lung Diseases; Malaria; Malaria, Falciparum; Malnutrition; Maxillary Sinusitis; Mycobacterium avium-intracellulare Infection; Mycobacterium Infections; Mycoses; Myocardial Infarction; Neonatal Sepsis; Otitis Media, Suppurative; Pneumonia, Viral; Pregnancy; Premature Birth; Respiratory Insufficiency; Severe Acute Respiratory Syndrome; Spotted Fever Group Rickettsiosis; Syphilis; Vomiting; Yaws; Bacterial Infections; Bronchitis, Chronic; Conjunctivitis, Bacterial; Cystic Fibrosis; Eye Infections; HIV Infections; Infections; Otitis Media; Pelvic Inflammatory Disease; Pharyngitis; Pneumonia; Pulmonary Disease, Chronic Obstructive; Sinusitis; Tonsillitis; Urethritis; Uterine Cervicitis

Bacterial 70S ribosome inhibitor


Small molecule Approved EMERGENCY MEDICINE; GASTROINTESTINAL; OTHER INJECTION; ORAL Brain Diseases; Brain Injuries; Dyspnea; Lecithin Cholesterol Acyltransferase Deficiency; Neuralgia; Opioid-Related Disorders; Pruritus; Small Cell Lung Carcinoma; Amphetamine-Related Disorders; Breast Neoplasms; Cholecystitis; Cocaine-Related Disorders; Dementia; Gastroparesis; Glioma; Hallucinations; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Obsessive-Compulsive Disorder; Pancreatic Neoplasms; Sarcoma; Tobacco Use Disorder; Tonsillitis; Alcoholism; Gastroenteritis; Genital Neoplasms, Female; HIV Infections; Hypotension; Irritable Bowel Syndrome; Pain; Schizophrenia; Syncope; Uterine Cervical Neoplasms; Vomiting; Nausea; Neoplasms; Postoperative Nausea and Vomiting Serotonin 3a (5-HT3a) receptor antagonist

Small molecule

Approved

EMERGENCY MEDICINE; GASTROINTESTINAL; OTHER

INJECTION; ORAL

Brain Diseases; Brain Injuries; Dyspnea; Lecithin Cholesterol Acyltransferase Deficiency; Neuralgia; Opioid-Related Disorders; Pruritus; Small Cell Lung Carcinoma; Amphetamine-Related Disorders; Breast Neoplasms; Cholecystitis; Cocaine-Related Disorders; Dementia; Gastroparesis; Glioma; Hallucinations; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Obsessive-Compulsive Disorder; Pancreatic Neoplasms; Sarcoma; Tobacco Use Disorder; Tonsillitis; Alcoholism; Gastroenteritis; Genital Neoplasms, Female; HIV Infections; Hypotension; Irritable Bowel Syndrome; Pain; Schizophrenia; Syncope; Uterine Cervical Neoplasms; Vomiting; Nausea; Neoplasms; Postoperative Nausea and Vomiting

Serotonin 3a (5-HT3a) receptor antagonist


Small molecule Approved OTHER ORAL Fissure in Ano; Pregnancy; Vascular Diseases; Heart Failure; Hypertension; Oligohydramnios; Stroke; Fetal Membranes, Premature Rupture; Angina Pectoris; Cardiovascular Diseases; Coronary Artery Disease Soluble guanylate cyclase activator


Protein Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER; PEDIATRICS INJECTION; SUBCUTANEOUS Prostatic Neoplasms Gonadotropin-releasing hormone receptor agonist


Small molecule Approved OTHER ORAL Unknown Unknown


Protein Approved DIABETES DRUGS & ENDOCRINOLOGY; HEMATOLOGY; OTHER UNKNOWN Adenocarcinoma; Anemia, Refractory, with Excess of Blasts; Carcinoma, Pancreatic Ductal; Hepatitis B, Chronic; Leukemia, Plasma Cell; Liver Neoplasms; Neoplasm Metastasis; Parkinson Disease; Periodontitis; Sepsis; Alzheimer Disease; Biliary Tract Neoplasms; Brain Neoplasms; Breast Neoplasms, Male; Carcinoma, Endometrioid; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Colorectal Neoplasms; Cystadenoma, Serous; Down Syndrome; Esophageal Neoplasms; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Glioblastoma; Gliosarcoma; Hematologic Neoplasms; HIV Infections; Hodgkin Disease; Inflammatory Breast Neoplasms; Kidney Diseases; Kidney Neoplasms; Leishmaniasis, Cutaneous; Leukemia, Lymphocytic, Chronic, B-Cell; Lung Neoplasms; Lymphoma, Follicular; Myelodysplastic-Myeloproliferative Diseases; Myeloproliferative Disorders; Neoplasms, Plasma Cell; Osteosarcoma; Ovarian Neoplasms; Peritoneal Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pulmonary Alveolar Proteinosis; Severe Acute Respiratory Syndrome; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Triple Negative Breast Neoplasms; Breast Neoplasms; Crohn Disease; Cytomegalovirus Retinitis; Ganglioneuroblastoma; Infections; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma; Lymphoma, Non-Hodgkin; Melanoma; Multiple Myeloma; Myelodysplastic Syndromes; Neuroblastoma; Pancreatic Neoplasms; Rhabdomyosarcoma; Sarcoma; Urinary Bladder Neoplasms; Uveal Melanoma; Leukemia, Myeloid, Acute; Neoplasms Granulocyte-macrophage colony-stimulating factor receptor agonist

Protein

Approved

DIABETES DRUGS & ENDOCRINOLOGY; HEMATOLOGY; OTHER

UNKNOWN

Adenocarcinoma; Anemia, Refractory, with Excess of Blasts; Carcinoma, Pancreatic Ductal; Hepatitis B, Chronic; Leukemia, Plasma Cell; Liver Neoplasms; Neoplasm Metastasis; Parkinson Disease; Periodontitis; Sepsis; Alzheimer Disease; Biliary Tract Neoplasms; Brain Neoplasms; Breast Neoplasms, Male; Carcinoma, Endometrioid; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Colorectal Neoplasms; Cystadenoma, Serous; Down Syndrome; Esophageal Neoplasms; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Glioblastoma; Gliosarcoma; Hematologic Neoplasms; HIV Infections; Hodgkin Disease; Inflammatory Breast Neoplasms; Kidney Diseases; Kidney Neoplasms; Leishmaniasis, Cutaneous; Leukemia, Lymphocytic, Chronic, B-Cell; Lung Neoplasms; Lymphoma, Follicular; Myelodysplastic-Myeloproliferative Diseases; Myeloproliferative Disorders; Neoplasms, Plasma Cell; Osteosarcoma; Ovarian Neoplasms; Peritoneal Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pulmonary Alveolar Proteinosis; Severe Acute Respiratory Syndrome; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Triple Negative Breast Neoplasms; Breast Neoplasms; Crohn Disease; Cytomegalovirus Retinitis; Ganglioneuroblastoma; Infections; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma; Lymphoma, Non-Hodgkin; Melanoma; Multiple Myeloma; Myelodysplastic Syndromes; Neuroblastoma; Pancreatic Neoplasms; Rhabdomyosarcoma; Sarcoma; Urinary Bladder Neoplasms; Uveal Melanoma; Leukemia, Myeloid, Acute; Neoplasms

Granulocyte-macrophage colony-stimulating factor receptor agonist


Small molecule Approved OTHER INJECTION Central Nervous System Neoplasms; Mycobacterium Infections; Neuroblastoma; Sarcoma; Cystic Fibrosis; Lymphoma; Lymphoma, Non-Hodgkin Hydroxyapatite sequestering agent


Small molecule Approved OTHER ORAL Hepatolenticular Degeneration; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Asperger Syndrome; Autistic Disorder Lead chelating agent


Small molecule Approved OTHER INJECTION Anxiety; Dental Anxiety; Disorders of Excessive Somnolence; Fragile X Syndrome; Idiopathic Hypersomnia; Narcolepsy; Parkinson Disease; Sleep Initiation and Maintenance Disorders; Alcoholism; Obsessive-Compulsive Disorder; Substance-Related Disorders GABA-A receptor; anion channel allosteric antagonist


Protein Approved CANCER; HEMATOLOGY; OTHER UNKNOWN Alzheimer Disease; beta-Thalassemia; Blast Crisis; Carcinoma, Endometrioid; Chordoma; Coronary Disease; Cystadenoma, Serous; Enterocolitis, Necrotizing; Ganglioneuroblastoma; Glioma; Granulomatous Disease, Chronic; Hemangiosarcoma; Immunologic Deficiency Syndromes; Leukemia, Plasma Cell; Leukemia, Promyelocytic, Acute; Lymphoma, B-Cell, Marginal Zone; Menopause; Multiple Sclerosis; Muscular Diseases; Myasthenia Gravis; Neoplasm Metastasis; Neurilemmoma; Peripheral Arterial Disease; Peripheral Vascular Diseases; Primary Myelofibrosis; Sarcoma, Synovial; Severe Combined Immunodeficiency; Stiff-Person Syndrome; Vasculitis; Waldenstrom Macroglobulinemia; Amyotrophic Lateral Sclerosis; Anemia, Diamond-Blackfan; Anemia, Sickle Cell; Biliary Atresia; Breast Neoplasms, Male; Carcinoid Tumor; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Large Cell; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Cardiomyopathy, Dilated; Cerebral Palsy; Colorectal Neoplasms; Crohn Disease; Diabetes Mellitus, Type 1; Endometriosis; Epidermolysis Bullosa Dystrophica; Esophageal Neoplasms; Fallopian Tube Neoplasms; Fanconi Anemia; Gallbladder Neoplasms; Glioblastoma; Gliosarcoma; Hematologic Diseases; Hematologic Neoplasms; Histiocytosis, Langerhans-Cell; HIV Infections; Infertility; Inflammatory Breast Neoplasms; Ischemic Stroke; Leukemia, Mast-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Liver Neoplasms; Lupus Erythematosus, Systemic; Lymphoma, AIDS-Related; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell; Lymphoma, T-Cell, Peripheral; Lymphopenia; Myelodysplastic-Myeloproliferative Diseases; Nasopharyngeal Carcinoma; Neuromyelitis Optica; Osteosarcoma; Pancreatic Neoplasms; Parkinson Disease; Pemphigus; Peritoneal Neoplasms; Prostatic Neoplasms; Sarcoma, Ewing; Small Cell Lung Carcinoma; Stomach Neoplasms; Stroke; Urethral Neoplasms; Uterine Cervical Neoplasms; Wilms Tumor; Adrenal Cortex Neoplasms; Amyloidosis, Familial; Anemia; Anemia, Aplastic; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Brain Neoplasms; Breast Neoplasms; Burkitt Lymphoma; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Chagas Cardiomyopathy; Endometrial Neoplasms; Ependymoma; Fever; Graft vs Host Disease; Head and Neck Neoplasms; Hepatitis, Alcoholic; Hodgkin Disease; Hot Flashes; Kidney Neoplasms; Leukemia; Leukemia, Basophilic, Acute; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Liver Cirrhosis; Liver Diseases; Liver Failure; Lung Neoplasms; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Mediastinal Neoplasms; Medulloblastoma; Melanoma; Multiple Myeloma; Multiple Sclerosis, Relapsing-Remitting; Myelodysplastic Syndromes; Myeloproliferative Disorders; Myocardial Infarction; Neoplasms, Germ Cell and Embryonal; Neoplasms, Plasma Cell; Neuroblastoma; Neuroectodermal Tumors, Primitive; Ovarian Neoplasms; Pheochromocytoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Ovarian Insufficiency; Prostatic Neoplasms, Castration-Resistant; Retinoblastoma; Rhabdomyosarcoma; Sarcoma; Scleroderma, Systemic; ST Elevation Myocardial Infarction; Testicular Neoplasms; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Uterine Neoplasms; Hematopoietic Stem Cell Transplantation; Infections; Neoplasms; Neutropenia Granulocyte colony stimulating factor receptor agonist

Protein

Approved

CANCER; HEMATOLOGY; OTHER

UNKNOWN

Alzheimer Disease; beta-Thalassemia; Blast Crisis; Carcinoma, Endometrioid; Chordoma; Coronary Disease; Cystadenoma, Serous; Enterocolitis, Necrotizing; Ganglioneuroblastoma; Glioma; Granulomatous Disease, Chronic; Hemangiosarcoma; Immunologic Deficiency Syndromes; Leukemia, Plasma Cell; Leukemia, Promyelocytic, Acute; Lymphoma, B-Cell, Marginal Zone; Menopause; Multiple Sclerosis; Muscular Diseases; Myasthenia Gravis; Neoplasm Metastasis; Neurilemmoma; Peripheral Arterial Disease; Peripheral Vascular Diseases; Primary Myelofibrosis; Sarcoma, Synovial; Severe Combined Immunodeficiency; Stiff-Person Syndrome; Vasculitis; Waldenstrom Macroglobulinemia; Amyotrophic Lateral Sclerosis; Anemia, Diamond-Blackfan; Anemia, Sickle Cell; Biliary Atresia; Breast Neoplasms, Male; Carcinoid Tumor; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Large Cell; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Cardiomyopathy, Dilated; Cerebral Palsy; Colorectal Neoplasms; Crohn Disease; Diabetes Mellitus, Type 1; Endometriosis; Epidermolysis Bullosa Dystrophica; Esophageal Neoplasms; Fallopian Tube Neoplasms; Fanconi Anemia; Gallbladder Neoplasms; Glioblastoma; Gliosarcoma; Hematologic Diseases; Hematologic Neoplasms; Histiocytosis, Langerhans-Cell; HIV Infections; Infertility; Inflammatory Breast Neoplasms; Ischemic Stroke; Leukemia, Mast-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Liver Neoplasms; Lupus Erythematosus, Systemic; Lymphoma, AIDS-Related; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell; Lymphoma, T-Cell, Peripheral; Lymphopenia; Myelodysplastic-Myeloproliferative Diseases; Nasopharyngeal Carcinoma; Neuromyelitis Optica; Osteosarcoma; Pancreatic Neoplasms; Parkinson Disease; Pemphigus; Peritoneal Neoplasms; Prostatic Neoplasms; Sarcoma, Ewing; Small Cell Lung Carcinoma; Stomach Neoplasms; Stroke; Urethral Neoplasms; Uterine Cervical Neoplasms; Wilms Tumor; Adrenal Cortex Neoplasms; Amyloidosis, Familial; Anemia; Anemia, Aplastic; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Brain Neoplasms; Breast Neoplasms; Burkitt Lymphoma; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Chagas Cardiomyopathy; Endometrial Neoplasms; Ependymoma; Fever; Graft vs Host Disease; Head and Neck Neoplasms; Hepatitis, Alcoholic; Hodgkin Disease; Hot Flashes; Kidney Neoplasms; Leukemia; Leukemia, Basophilic, Acute; Leukemia, Biphenotypic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Liver Cirrhosis; Liver Diseases; Liver Failure; Lung Neoplasms; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Mediastinal Neoplasms; Medulloblastoma; Melanoma; Multiple Myeloma; Multiple Sclerosis, Relapsing-Remitting; Myelodysplastic Syndromes; Myeloproliferative Disorders; Myocardial Infarction; Neoplasms, Germ Cell and Embryonal; Neoplasms, Plasma Cell; Neuroblastoma; Neuroectodermal Tumors, Primitive; Ovarian Neoplasms; Pheochromocytoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Ovarian Insufficiency; Prostatic Neoplasms, Castration-Resistant; Retinoblastoma; Rhabdomyosarcoma; Sarcoma; Scleroderma, Systemic; ST Elevation Myocardial Infarction; Testicular Neoplasms; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Uterine Neoplasms; Hematopoietic Stem Cell Transplantation; Infections; Neoplasms; Neutropenia

Granulocyte colony stimulating factor receptor agonist


Small molecule Approved OTHER ORAL Atherosclerosis; Coronary Disease; Diabetes Mellitus, Type 2; Hypercholesterolemia; Cardiovascular Diseases; Diabetes Mellitus; Hypertension Mineralocorticoid receptor antagonist


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; MUSCULOSKELETAL; OTHER; RHEUMATOLOGY ORAL Lecithin Cholesterol Acyltransferase Deficiency; Carcinoma, Hepatocellular; Pancreatic Neoplasms; Colorectal Neoplasms; Muscular Diseases; Pain; Sprains and Strains; Acute Pain; Arthritis, Juvenile; Arthritis, Rheumatoid; Osteoarthritis; Rheumatic Diseases Cyclooxygenase-2 inhibitor


Small molecule Approved IMMUNE SYSTEM; OTHER ORAL AIDS Dementia Complex; Lymphoma; Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Tuberculosis; HIV Infections; Virus Diseases Human immunodeficiency virus type 1 reverse transcriptase inhibitor


Small molecule Approved OTHER ORAL Amyotrophic Lateral Sclerosis; Osteomyelitis; Bacterial Infections DNA gyrase inhibitor


Small molecule Approved OTHER ORAL Lecithin Cholesterol Acyltransferase Deficiency; Acute Coronary Syndrome; Muscular Dystrophy, Duchenne; Hypertension Beta-1 adrenergic receptor antagonist


Small molecule Approved OTHER ORAL Osteomyelitis; Lung Diseases; Tuberculosis, Pulmonary; Crohn Disease; Infections; Mycobacterium Infections; Mycoses; HIV Infections; Mycobacterium avium-intracellulare Infection; Tuberculosis Bacterial DNA-directed RNA polymerase inhibitor


Small molecule Approved OTHER INHALATION Postoperative Complications; Renal Insufficiency GABA-A receptor; anion channel positive allosteric modulator


Small molecule Approved IMMUNE SYSTEM; OTHER TOPICAL Hepatitis B, Chronic; Mycoses; Colitis, Ulcerative; Crohn Disease; Tinea Pedis; Onychomycosis; Tinea Squalene monooxygenase inhibitor


Small molecule Approved OTHER TOPICAL Prostatic Neoplasms, Castration-Resistant; Neoplasms Insulin-like growth factor I receptor inhibitor


Small molecule Approved IMMUNE SYSTEM; OTHER INJECTION; ORAL Alzheimer Disease; Amyotrophic Lateral Sclerosis; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Asthma; Bacterial Infections; Cachexia; Celiac Disease; Cystic Fibrosis; Diabetic Foot; Erectile Dysfunction; Esophageal Neoplasms; Glioblastoma; Heart Failure; Hepatitis B, Chronic; Hepatitis C, Chronic; Infections; Inflammatory Bowel Diseases; Lymphoma; Lymphoma, Non-Hodgkin; Malaria; Melanoma; Multiple Myeloma; Muscular Atrophy, Spinal; Myelodysplastic Syndromes; Neoplasm Metastasis; Neuralgia; Obesity; Pain; Polycystic Ovary Syndrome; Primary Myelofibrosis; Pulmonary Disease, Chronic Obstructive; Renal Insufficiency, Chronic; Respiratory Syncytial Virus Infections; Severe Acute Respiratory Syndrome; Sporotrichosis; Thrombosis; Burns; Carcinoma, Basal Cell; Carcinoma, Non-Small-Cell Lung; Coccidioidomycosis; Crohn Disease; Hematologic Diseases; Leukemia, Myeloid, Acute; Lung Neoplasms; Meningitis, Cryptococcal; Mycetoma; Opioid-Related Disorders; Ovarian Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sinusitis; Skin Neoplasms; Tinea Pedis; Tinea Versicolor; Aspergillosis, Allergic Bronchopulmonary; Bronchiectasis; Cryptococcosis; Histoplasmosis; Neoplasms; Aspergillosis; Blastomycosis; Candidiasis; Lung Diseases; Mycoses; Onychomycosis Cytochrome P450 51 inhibitor

Small molecule

Approved

IMMUNE SYSTEM; OTHER

INJECTION; ORAL

Alzheimer Disease; Amyotrophic Lateral Sclerosis; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Asthma; Bacterial Infections; Cachexia; Celiac Disease; Cystic Fibrosis; Diabetic Foot; Erectile Dysfunction; Esophageal Neoplasms; Glioblastoma; Heart Failure; Hepatitis B, Chronic; Hepatitis C, Chronic; Infections; Inflammatory Bowel Diseases; Lymphoma; Lymphoma, Non-Hodgkin; Malaria; Melanoma; Multiple Myeloma; Muscular Atrophy, Spinal; Myelodysplastic Syndromes; Neoplasm Metastasis; Neuralgia; Obesity; Pain; Polycystic Ovary Syndrome; Primary Myelofibrosis; Pulmonary Disease, Chronic Obstructive; Renal Insufficiency, Chronic; Respiratory Syncytial Virus Infections; Severe Acute Respiratory Syndrome; Sporotrichosis; Thrombosis; Burns; Carcinoma, Basal Cell; Carcinoma, Non-Small-Cell Lung; Coccidioidomycosis; Crohn Disease; Hematologic Diseases; Leukemia, Myeloid, Acute; Lung Neoplasms; Meningitis, Cryptococcal; Mycetoma; Opioid-Related Disorders; Ovarian Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sinusitis; Skin Neoplasms; Tinea Pedis; Tinea Versicolor; Aspergillosis, Allergic Bronchopulmonary; Bronchiectasis; Cryptococcosis; Histoplasmosis; Neoplasms; Aspergillosis; Blastomycosis; Candidiasis; Lung Diseases; Mycoses; Onychomycosis

Cytochrome P450 51 inhibitor


Small molecule Approved OTHER INJECTION Leukemia; Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Neoplasms DNA topoisomerase II inhibitor


Small molecule Approved OTHER ORAL Carcinoma, Non-Small-Cell Lung; Gastroesophageal Reflux; Leukemia, Myeloid, Acute; Infections; Severe Acute Respiratory Syndrome; Toxoplasmosis, Cerebral; Malaria, Falciparum; Amebiasis; Malaria; Pneumocystis Infections; Pneumonia, Pneumocystis Cytochrome b inhibitor


Small molecule Approved OTHER ORAL Arthritis, Juvenile; Arthritis, Rheumatoid; Osteoarthritis; Rheumatic Diseases Cyclooxygenase inhibitor


Small molecule Approved OTHER ORAL Osteomyelitis; Otitis Media Bacterial penicillin-binding protein inhibitor


Small molecule Approved OTHER ORAL HIV Infections; Virus Diseases Human immunodeficiency virus type 1 reverse transcriptase inhibitor


Small molecule Approved DERMATOLOGY; DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Hyperplasia; Hypogonadism; Acne Vulgaris; Carcinoma, Non-Small-Cell Lung; Prostatic Neoplasms, Castration-Resistant; Retinal Diseases; Alopecia; Prostatic Hyperplasia; Prostatic Neoplasms Steroid 5-alpha-reductase 2 inhibitor


Small molecule Approved OTHER INJECTION Astrocytoma; Glioblastoma; Glioma; Multiple Sclerosis, Chronic Progressive; Paraganglioma; Central Nervous System Diseases Diagnostic agent

Small molecule

Approved

CANCER; OTHER; RESPIRATORY

INJECTION; IV (INFUSION)

Anus Neoplasms; Brain Neoplasms; Carcinoid Tumor; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Renal Cell; Carcinoma, Small Cell; Carcinoma, Verrucous; Coronary Restenosis; Glioblastoma; Gliosarcoma; Hodgkin Disease; Leukemia, Lymphocytic, Chronic, B-Cell; Liver Neoplasms; Mesothelioma; Neoplasms, Cystic, Mucinous, and Serous; Rectal Neoplasms; Thyroid Carcinoma, Anaplastic; Vaginal Neoplasms; Adenocarcinoma, Bronchiolo-Alveolar; Adrenal Cortex Neoplasms; Arthritis, Rheumatoid; Bone Neoplasms; Breast Carcinoma In Situ; Carcinoma, Ductal; Carcinoma, Endometrioid; Carcinoma, Hepatocellular; Carcinoma, Merkel Cell; Carcinoma, Neuroendocrine; Carcinoma, Ovarian Epithelial; Central Nervous System Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms; Constriction, Pathologic; Cystadenoma, Serous; Digestive System Diseases; Gallbladder Neoplasms; Gastrointestinal Stromal Tumors; Glioma; Hemangiosarcoma; Hereditary Breast and Ovarian Cancer Syndrome; Hypopharyngeal Neoplasms; Keratosis, Actinic; Kidney Neoplasms; Leukemia; Lymphoma; Mouth Neoplasms; Multiple Myeloma; Neoplasms, Complex and Mixed; Neoplasms, Germ Cell and Embryonal; Oropharyngeal Neoplasms; Penile Neoplasms; Peripheral Vascular Diseases; Prostatic Hyperplasia; Prostatic Neoplasms; Psoriasis; Salivary Gland Neoplasms; Small Cell Lung Carcinoma; Thymoma; Uterine Cervical Dysplasia; Uveal Melanoma; Vulvar Neoplasms; Adenocarcinoma; Adenocarcinoma of Lung; Anemia; Biliary Tract Neoplasms; Breast Neoplasms, Male; Carcinoma, Large Cell; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Endometrial Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Genital Neoplasms, Female; Gestational Trophoblastic Disease; Head and Neck Neoplasms; HIV Infections; Hypersensitivity; Inflammatory Breast Neoplasms; Ischemia; Lung Neoplasms; Lymphoma, Non-Hodgkin; Melanoma; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Pain; Paraganglioma; Peripheral Arterial Disease; Peripheral Nervous System Diseases; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Retroviridae Infections; Sarcoma; Sex Cord-Gonadal Stromal Tumors; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Teratoma; Testicular Neoplasms; Thyroid Neoplasms; Triple Negative Breast Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Non-Small-Cell Lung; Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Sarcoma, Kaposi

Tubulin inhibitor


Small molecule Approved OTHER OPHTHALMIC Unknown Unknown

Small molecule

Approved

OTHER

INJECTION; ORAL

Central Nervous System Neoplasms; Graft vs Host Disease; Multiple Myeloma; Myeloproliferative Disorders; Neoplasms, Plasma Cell; Cholangitis, Sclerosing; Histiocytosis; Histiocytosis, Langerhans-Cell; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Mantle-Cell; Mastocytosis, Systemic; Multiple Sclerosis, Chronic Progressive; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, T-Cell, Peripheral; Multiple Sclerosis, Relapsing-Remitting; Anemia; Immune System Diseases; Leukemia, Hairy Cell; Multiple Sclerosis; Neoplasms

DNA inhibitor

Small molecule

Approved

IMMUNE SYSTEM; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS

ORAL

Alopecia; Child Development Disorders, Pervasive; Glioblastoma; Premature Birth; Psychotic Disorders; Abortion, Spontaneous; Anemia, Sickle Cell; Breast Neoplasms; HIV Infections; Hyperemesis Gravidarum; Intervertebral Disc Displacement; Low Back Pain; Marijuana Abuse; Mucositis; Multiple Sclerosis; Neoplasms; Paget Disease, Extramammary; Peripheral Nervous System Diseases; Postoperative Complications; Prostatic Neoplasms, Castration-Resistant; Rotator Cuff Injuries; Sleep Wake Disorders; Substance-Related Disorders; Substance Withdrawal Syndrome; Tinnitus; Tobacco Use Disorder; Urinary Bladder Neoplasms; Wounds and Injuries; Alcohol Drinking; Alcoholism; Anxiety; Azoospermia; Brain Injuries; Carpal Tunnel Syndrome; Chronic Pain; Cystitis, Interstitial; Delirium; Dementia; Depressive Disorder; Diabetic Neuropathies; Dyspepsia; Epilepsies, Partial; Fibromyalgia; Head and Neck Neoplasms; Herpes Zoster; Hot Flashes; Intervertebral Disc Degeneration; Liver Cirrhosis; Lung Diseases; Neuralgia; Opioid-Related Disorders; Oropharyngeal Neoplasms; Pain; Pelvic Organ Prolapse; Postoperative Nausea and Vomiting; Pruritus; Schizophrenia; Scoliosis; Sleep Initiation and Maintenance Disorders; Tremor; Vomiting; Epilepsy; Neuralgia, Postherpetic; Restless Legs Syndrome; Seizures

Voltage-gated calcium channel modulator


Small molecule Approved OTHER INJECTION Unknown Diagnostic agent

Small molecule

Approved

CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER

ORAL

Cholangitis, Sclerosing; Alcoholism; Burns; Diabetic Nephropathies; HIV Infections; Huntington Disease; Inflammatory Bowel Diseases; Metabolic Syndrome; Multiple Myeloma; Non-alcoholic Fatty Liver Disease; Obesity; Atherosclerosis; Coronary Disease; Diabetic Retinopathy; Hyperlipidemia, Familial Combined; Hyperlipidemias; Hyperlipoproteinemias; Hyperlipoproteinemia Type III; Hypertension; Hypertriglyceridemia; Lipid Metabolism Disorders; Lipodystrophy; Liver Cirrhosis, Biliary; Metabolic Diseases; Cardiovascular Diseases; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dyslipidemias; Hypercholesterolemia; Hypothyroidism

Peroxisome proliferator-activated receptor alpha agonist


Small molecule Approved OTHER ORAL Bipolar Disorder; Anemia; Epilepsy; Seizures Glutamate [NMDA] receptor antagonist