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Total: 10647
Small molecule
Unknown
Unknown
Unknown
Amyotrophic Lateral Sclerosis; Cystic Fibrosis; Lymphoma; Muscular Atrophy, Spinal; Myelodysplastic-Myeloproliferative Diseases; Myelodysplastic Syndromes; Pyruvate Dehydrogenase Complex Deficiency Disease; Argininosuccinic Aciduria; HIV Infections; Huntington Disease; Leukemia; Machado-Joseph Disease; Tuberculosis, Pulmonary; Hyperammonemia; Urea Cycle Disorders, Inborn
Glutamine sequestering agent
Small molecule
Approved
Unknown
Unknown
Hepatopulmonary Syndrome; Hypotension, Orthostatic; Ischemic Stroke; Ascites; Hypotension; Shock, Septic; Spinal Cord Injuries; Cardiovascular Diseases
Unknown
Enzyme
Approved
Unknown
Unknown
Hypoglycemia; Pancreatic Neoplasms; Pancreatitis; Cystic Fibrosis; Exocrine Pancreatic Insufficiency; Pancreatitis, Chronic
Fatty acids hydrolytic enzyme
Small molecule
Approved
CANCER; OTHER; PREGNANCY AND GYNECOLOGY
INJECTION; INTRAVENOUS
Breast Neoplasms, Male; Carcinoma, Endometrioid; Carcinoma, Renal Cell; Colonic Neoplasms; Cystadenoma, Serous; Digestive System Diseases; Lymphoma; Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Nausea; Sarcoma, Synovial; Vaginal Neoplasms; Vulvar Neoplasms; Adenocarcinoma; Anus Neoplasms; Biliary Tract Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Neuroendocrine; Carcinoma, Transitional Cell; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Hereditary Breast and Ovarian Cancer Syndrome; Leiomyosarcoma; Leukemia; Liver Neoplasms; Mediastinal Neoplasms; Melanoma; Osteosarcoma; Pancreatic Neoplasms; Penile Neoplasms; Retroviridae Infections; Small Cell Lung Carcinoma; Squamous Cell Carcinoma of Head and Neck; Testicular Neoplasms; Thyroid Carcinoma, Anaplastic; Tonsillar Neoplasms; Triple Negative Breast Neoplasms; Uterine Neoplasms; Adenocarcinoma of Lung; Anorexia; Cachexia; Carcinoma; Carcinoma, Squamous Cell; Endometrial Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Fatigue; Genital Neoplasms, Male; Head and Neck Neoplasms; Hypersensitivity; Hypopharyngeal Neoplasms; Inflammatory Breast Neoplasms; Kidney Neoplasms; Laryngeal Neoplasms; Lung Neoplasms; Mouth Neoplasms; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neutropenia; Oropharyngeal Neoplasms; Ovarian Neoplasms; Paranasal Sinus Neoplasms; Peritoneal Neoplasms; Pharyngeal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Stomach Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasms
Tubulin inhibitor
Small molecule
Approved
Unknown
TOPICAL
Herpes Labialis; Virus Diseases
Human herpesvirus 1 DNA polymerase inhibitor
Small molecule
Approved
EYE; IMMUNE SYSTEM; OTHER
INJECTION
Herpes Simplex; Kidney Diseases; Uterine Cervical Neoplasms; Anus Neoplasms; Infections; Papilloma; Sarcoma; Uterine Cervical Dysplasia; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Primary Immunodeficiency Diseases; Virus Diseases
Human herpesvirus 1 DNA polymerase inhibitor
Small molecule
Approved
DIABETES DRUGS & ENDOCRINOLOGY; OTHER
ORAL
Postoperative Nausea and Vomiting; Sleep Apnea, Obstructive; Alcoholism; Amphetamine-Related Disorders; Cocaine-Related Disorders; Fibromyalgia; Glioma; Substance-Related Disorders; Weight Loss; Anorexia; Anxiety; Cachexia; Child Development Disorders, Pervasive; Dementia; Heroin Dependence; Nausea; Schizophrenia; Depressive Disorder; Depressive Disorder, Major; Sleep Initiation and Maintenance Disorders
Adrenergic receptor alpha-2 antagonist
Unknown
Approved
OTHER
TOPICAL
Unknown
Unknown
Small molecule
Approved
Unknown
ORAL
Hepatitis C, Chronic; Infertility, Male; Hepatitis C; Hyperoxaluria, Primary; Non-alcoholic Fatty Liver Disease; Obesity; Depressive Disorder; Homocystinuria
Betaine-homocysteine S-methyltransferase substrate
Enzyme
Approved
Unknown
Unknown
Pancreatitis, Chronic
Fatty acids hydrolytic enzyme
Protein
Approved
Unknown
INTRAVENOUS; SUBCUTANEOUS
Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Hyperglycemia; Diabetes Mellitus
Insulin receptor agonist
Enzyme
Approved
Unknown
Unknown
Borderline Personality Disorder; Diarrhea; Malnutrition
Starch hydrolytic enzyme
Small molecule
Approved
Unknown
Unknown
Conjunctivitis, Allergic; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Eye Manifestations; Nasal Obstruction
Unknown
Enzyme
Approved
CARDIOVASCULAR
UNKNOWN
Stroke; Myocardial Infarction; Heart Failure; ST Elevation Myocardial Infarction; Thrombosis
Plasminogen activator
Enzyme
Approved
OTHER
SINGLE-USE; UNKNOWN
Retinal Vein Occlusion; Thrombophlebitis; Abdominal Abscess; Bronchitis; Neoplasms; Nervous System Diseases; Severe Acute Respiratory Syndrome; Urinary Retention; Venous Thrombosis; Abscess; Angina, Stable; Brain Ischemia; Cerebral Hemorrhage; Cerebral Infarction; Empyema; Empyema, Pleural; Hemorrhage; Ischemic Stroke; Myocardial Ischemia; Respiratory Distress Syndrome; Retinal Artery Occlusion; Subarachnoid Hemorrhage; Eye Diseases; Heart Failure; Myocardial Infarction; Pulmonary Embolism; Stroke; Thrombosis
Plasminogen activator
Small molecule
Approved
OTHER
INJECTION
Diffuse Intrinsic Pontine Glioma; Bile Duct Neoplasms; Brain Neoplasms; Leukemia; Lymphoma, T-Cell, Cutaneous; Sarcoma, Synovial; Stomach Neoplasms; Adenocarcinoma; Adenocarcinoma of Lung; Anxiety; Biliary Tract Diseases; Carcinoma, Large Cell; Carcinoma, Renal Cell; Colonic Neoplasms; Colorectal Neoplasms; Digestive System Diseases; Endometrial Neoplasms; Esophageal Neoplasms; Gastrointestinal Stromal Tumors; Head and Neck Neoplasms; Hodgkin Disease; Kidney Neoplasms; Leiomyosarcoma; Leukemia-Lymphoma, Adult T-Cell; Liver Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, T-Cell; Medulloblastoma; Melanoma; Multiple Myeloma; Neoplasms, Germ Cell and Embryonal; Osteosarcoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Small Cell Lung Carcinoma; Testicular Neoplasms; Thyroid Neoplasms; Urethral Neoplasms; Biliary Tract Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cholangiocarcinoma; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Granuloma, Lethal Midline; Hepatoblastoma; Immunoblastic Lymphadenopathy; Lung Neoplasms; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Mesothelioma; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Sarcoma; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Neoplasms
Unknown
Small molecule
Approved
DERMATOLOGY; OTHER
TOPICAL
Skin Diseases; Acne Vulgaris
Retinoic acid receptor agonist
Unknown
Approved
CANCER
ORAL
Unknown
Unknown
Unknown
Approved
OTHER
INJECTION
Unknown
Unknown
Unknown
Approved
DERMATOLOGY; IMMUNE SYSTEM; OTHER; PEDIATRICS
ORAL; TOPICAL
Alcoholism; Infections; Acne Vulgaris; Dengue; Dermatitis, Atopic; Severe Dengue; Trichuriasis; Blepharitis; Elephantiasis, Filarial; Malaria; Severe Acute Respiratory Syndrome; Helminthiasis; Lice Infestations; Onchocerciasis; Rosacea; Strongyloidiasis
Glutamate-gated chloride channel modulator
Small molecule
Approved
IMMUNE SYSTEM
ORAL
Hookworm Infections; Trichuriasis; Cysticercosis; Ectoparasitic Infestations; Elephantiasis, Filarial; Filariasis; HIV Infections; Malaria; Malnutrition; Onchocerciasis; Strongyloidiasis; Toxocariasis; Helminthiasis; Infections; Neurocysticercosis
Tubulin inhibitor
Protein
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
UNKNOWN
Stroke; Alzheimer Disease; Asthma; Colitis, Ulcerative; Crohn Disease; Multiple Organ Failure; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Pulmonary Disease, Chronic Obstructive; Hepatitis C; Multiple Sclerosis, Relapsing-Remitting; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Multiple Sclerosis
Interferon alpha/beta receptor agonist
Small molecule
Approved
Unknown
Unknown
Attention Deficit Disorder with Hyperactivity
Dopamine transporter releasing agent
Antibody
Approved
OTHER
INTRAVENOUS
Unknown
Diagnostic agent
Small molecule
Approved
Unknown
Unknown
Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Neuroblastoma; Uterine Cervical Neoplasms; Uterine Neoplasms; Ovarian Neoplasms; Small Cell Lung Carcinoma; Neoplasms
Unknown
Small molecule
Approved
Unknown
Unknown
Osteomyelitis; Kidney Diseases; Communicable Diseases; Enterobacteriaceae Infections; Pyelonephritis; Shock, Septic; Urinary Tract Infections; Bacterial Infections
Unknown
Small molecule
Approved
Unknown
Unknown
Status Epilepticus; Epilepsy
Unknown
Small molecule
Approved
Unknown
Unknown
Attention Deficit Disorder with Hyperactivity; Narcolepsy
Dopamine transporter releasing agent
Protein
Unknown
Unknown
Unknown
Adenoma
Diagnostic agent
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
DIABETES DRUGS & ENDOCRINOLOGY; OTHER
ORAL
Diabetes Mellitus, Type 1; Diabetes Mellitus; Diabetes Mellitus, Type 2
Lysosomal alpha-glucosidase inhibitor
Small molecule
Unknown
Unknown
Unknown
Infections; Osteomyelitis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pseudomonas Infections; Appendicitis; Neonatal Sepsis; Neoplasms; Pneumonia, Bacterial; Pyelonephritis; Gonorrhea; Staphylococcal Infections; Urinary Tract Infections; Bacterial Infections
Unknown
Small molecule
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Hemorrhagic Fever, Ebola; Metabolic Syndrome; Breast Neoplasms; Hepatitis C; Paraplegia; Periodontitis; Atherosclerosis; Diabetes Mellitus; Diabetes Mellitus, Type 2; Hyperlipidemia, Familial Combined; Hyperlipidemias; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type III; Hyperlipoproteinemia Type IV; Hypertriglyceridemia; Lipid Metabolism Disorders; Cardiovascular Diseases; Coronary Artery Disease; Coronary Disease; Hypercholesterolemia
Unknown
Antibody
Approved
OTHER
UNKNOWN
Unknown
Unknown