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Total: 10647
Small molecule
Approved
Unknown
Unknown
Renal Insufficiency; Ischemic Stroke; Pneumonia, Viral; Respiratory Insufficiency; Severe Acute Respiratory Syndrome; Stroke; Venous Thromboembolism; Acute Coronary Syndrome; Coronary Disease; Myocardial Infarction; Thrombosis
Unknown
Protein
Unknown
Unknown
Unknown
Anemia, Sickle Cell; Brain Infarction; Coronary Disease; Pneumonia; Shock, Septic; ST Elevation Myocardial Infarction; Stroke; Cardiovascular Diseases; Ischemic Stroke; Myocardial Infarction; Acute Coronary Syndrome; Thrombosis
Integrin alpha-IIb/beta-3 inhibitor
Small molecule
Approved
Unknown
Unknown
Hepatitis C; Acidosis, Lactic; Lipodystrophy; Sarcoma, Kaposi; Acquired Immunodeficiency Syndrome; HIV Infections; Tuberculosis; Virus Diseases
Unknown
Small molecule
Approved
OTHER
OPHTHALMIC
Central Serous Chorioretinopathy; Glaucoma; Glaucoma, Open-Angle; Ocular Hypertension
Carbonic anhydrase II inhibitor
Small molecule
Approved
DIABETES DRUGS & ENDOCRINOLOGY; OTHER; UROLOGY AND KIDNEY
INJECTION; INTRAVENOUS; ORAL
Breast Neoplasms; Multiple Myeloma; Neoplasms; Rectal Neoplasms; Carcinoma, Pancreatic Ductal; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Hypocalcemia; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Albuminuria; Glomerulonephritis, IGA; Hyperparathyroidism; Hypertrophy, Left Ventricular; Kidney Diseases; Proteinuria; Hyperparathyroidism, Secondary; Parathyroid Diseases; Renal Insufficiency, Chronic
Vitamin D receptor agonist
Oligonucleotide
Approved
EYE
INJECTION
Cytomegalovirus Retinitis; Eye Infections
Major intermediate early region 2 mRNA antisense inhibitor
Antibody
Approved
OTHER; RESPIRATORY
UNKNOWN
Hernias, Diaphragmatic, Congenital; Respiratory Syncytial Virus Infections; Bronchopulmonary Dysplasia; Respiratory Tract Diseases
Fusion glycoprotein F0 inhibitor
Small molecule
Approved
Unknown
Unknown
Headache; Migraine Disorders
Unknown
Small molecule
Approved
OTHER; PREGNANCY AND GYNECOLOGY
ORAL
Sleep Apnea, Obstructive; Alzheimer Disease; HIV Infections; Albuminuria; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Essential Hypertension; Heart Diseases; Lipid Metabolism Disorders; Polycystic Kidney Diseases; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; Cardiovascular Diseases; Diabetes Mellitus; Hypertension; Myocardial Infarction; Stroke
Type-1 angiotensin II receptor antagonist
Small molecule
Approved
DIABETES DRUGS & ENDOCRINOLOGY; OTHER; RHEUMATOLOGY
ORAL
Breast Neoplasms; Graft vs Host Disease; HIV Infections; Melanoma; Severe Acute Respiratory Syndrome; Lupus Erythematosus, Systemic; Lymphoproliferative Disorders; Multiple Myeloma; Pemphigoid, Bullous; Prostatic Neoplasms, Castration-Resistant; Purpura, Schoenlein-Henoch; Smoldering Multiple Myeloma; Uveitis; Arthritis, Psoriatic; Central Nervous System Neoplasms; Lupus Nephritis; Myasthenia Gravis; Polymyalgia Rheumatica; Arthritis, Rheumatoid; Immune System Diseases; Multiple Sclerosis
Dihydroorotate dehydrogenase inhibitor
Small molecule
Approved
Unknown
Unknown
Chronic Kidney Disease-Mineral and Bone Disorder; Fibrous Dysplasia of Bone; Lung Neoplasms; Menopause; Back Pain; Bone Diseases, Metabolic; Osteitis Deformans; Osteoporosis; Osteoporosis, Postmenopausal; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Spinal Cord Injuries; Bone Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Neuralgia; Kidney Calculi; Low Back Pain; Pain; Pelvic Organ Prolapse; Urinary Bladder, Overactive; Polyuria; Urinary Incontinence
Unknown
Protein
Unknown
Unknown
Unknown
Goiter, Nodular; Graves Disease; Thyroid Neoplasms
Thyroid stimulating hormone receptor agonist
Small molecule
Approved
OTHER
ORAL
Cognitive Dysfunction; Hypotension, Orthostatic; Melanoma; Psychotic Disorders; Sleep Apnea Syndromes; Sleep Initiation and Maintenance Disorders; Tinnitus; Tobacco Use Disorder; Alcoholism; Amphetamine-Related Disorders; Deglutition Disorders; Depressive Disorder; Opioid-Related Disorders; Ovarian Neoplasms; Parkinson Disease; Schizophrenia; Stress Disorders, Post-Traumatic; Substance-Related Disorders; Alzheimer Disease; Brain Neoplasms; Cocaine-Related Disorders; Depressive Disorder, Major; Fatigue; Multiple Sclerosis; Narcolepsy; Postpoliomyelitis Syndrome; Sarcoma, Ewing; Sleep Apnea, Obstructive; Sleep Wake Disorders; Stroke; Attention Deficit Disorder with Hyperactivity
Dopamine transporter inhibitor
Protein
Approved
Unknown
Unknown
Unknown
Diagnostic agent
Small molecule
Approved
Unknown
Unknown
Acute Coronary Syndrome; Child Development Disorders, Pervasive; Alcoholism; Bipolar Disorder; Cocaine-Related Disorders; Irritable Bowel Syndrome; Opioid-Related Disorders; Panic Disorder; Parkinson Disease; Stroke; Anxiety; Dementia; Depressive Disorder, Major; Obsessive-Compulsive Disorder; Psychomotor Agitation; Schizophrenia; Depressive Disorder
Unknown
Small molecule
Approved
NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
ORAL
Cocaine-Related Disorders; Neuroblastoma; Alcoholism; Brain Injuries; Gambling; Obsessive-Compulsive Disorder; Pick Disease of the Brain; Schizophrenia; Tobacco Use Disorder; Liver Failure; Parkinson Disease
Catechol O-methyltransferase inhibitor
Small molecule
Approved
RESPIRATORY
ORAL
Osteomyelitis; HIV Infections; Tuberculosis, Pulmonary; Tuberculosis
Bacterial DNA-directed RNA polymerase inhibitor
Protein
Approved
Unknown
Unknown
Lung Neoplasms; Thrombosis
Thrombin inhibitor
Antibody
Approved
DIABETES DRUGS & ENDOCRINOLOGY; IMMUNE SYSTEM; OTHER
SINGLE-USE
DiGeorge Syndrome; Kidney Tubular Necrosis, Acute; Leukemia, Myeloid, Acute; Multiple Myeloma; Neoplasms; Uremia; Amyotrophic Lateral Sclerosis; Colitis, Ulcerative; Glioblastoma; Glomerulosclerosis, Focal Segmental; Granuloma, Lethal Midline; Hodgkin Disease; Kidney Diseases; Renal Insufficiency, Chronic; Uveitis; Diabetes Mellitus, Type 1; Emphysema; Graft vs Host Disease; Infections; Reperfusion Injury; Immune System Diseases
Interleukin-2 receptor inhibitor
Small molecule
Approved
DERMATOLOGY; OTHER
ORAL
Endometriosis; Epilepsy; Scleroderma, Systemic; Acquired Immunodeficiency Syndrome; Alzheimer Disease; Amyloidosis; Amyotrophic Lateral Sclerosis; Appendiceal Neoplasms; Brain Stem Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Castleman Disease; Central Nervous System Neoplasms; Cholangitis, Sclerosing; Colonic Neoplasms; Esophageal Neoplasms; Glioblastoma; Glioma; Head and Neck Neoplasms; Hepatitis C; Histiocytosis, Langerhans-Cell; HIV Infections; HIV Wasting Syndrome; Hodgkin Disease; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Liver Neoplasms; Lupus Erythematosus, Discoid; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Medulloblastoma; Melanoma; Mouth Neoplasms; Neuroblastoma; Neuroendocrine Tumors; Pain; Pancreatitis, Chronic; Primary Myelofibrosis; Proctitis; Prostatic Neoplasms; Psoriasis; Purpura, Thrombocytopenic, Idiopathic; Retroviridae Infections; Sarcoma; Severe Acute Respiratory Syndrome; Spondylitis, Ankylosing; Thalassemia; Waldenstrom Macroglobulinemia; Amyloidosis, Familial; Carcinoma, Hepatocellular; Colitis, Ulcerative; Colorectal Neoplasms; Cough; Crohn Disease; Fallopian Tube Neoplasms; Granuloma, Lethal Midline; Hypoalbuminemia; Idiopathic Pulmonary Fibrosis; Kidney Neoplasms; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Myelodysplastic Syndromes; Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoidosis; Vascular Malformations; Immune System Diseases; Multiple Myeloma
CRL4(CRBN) E3 ubiquitin ligase inhibitor
Unknown
Approved
OTHER
INTRATRACHEAL
Acute Lung Injury; Bronchopulmonary Dysplasia; Respiratory Distress Syndrome; Respiratory Distress Syndrome, Newborn
Surfactant agent
Small molecule
Approved
Unknown
Unknown
Migraine with Aura; Migraine without Aura; Migraine Disorders
Unknown
Small molecule
Approved
Unknown
Unknown
Anemia, Hemolytic, Autoimmune; Bronchopulmonary Dysplasia; HIV Infections; Immune System Diseases; Neoplasms; Non-alcoholic Fatty Liver Disease; Respiratory Tract Diseases; Alzheimer Disease; Anemia, Sickle Cell; Cough; Leukemia, Myeloid, Acute; Multiple Myeloma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Premature Birth; Severe Dengue; Sleep Apnea Syndromes; Status Asthmaticus; Arthritis, Rheumatoid; Eosinophilic Esophagitis; Pain; Respiratory Sounds; Rhinitis, Allergic, Perennial; Severe Acute Respiratory Syndrome; Sleep Apnea, Obstructive; Asthma; Asthma, Exercise-Induced; Lung Diseases, Obstructive; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal
Unknown
Small molecule
Approved
IMMUNE SYSTEM; OTHER
ORAL
Diabetes Mellitus, Type 2; Hepatitis C; Lymphoma, Non-Hodgkin; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Acquired Immunodeficiency Syndrome; Tuberculosis; Autoimmune Diseases; HIV Infections; Infections; Virus Diseases
Human immunodeficiency virus type 1 reverse transcriptase inhibitor
Antibody
Approved
PREGNANCY AND GYNECOLOGY
INTRAVENOUS
Adenocarcinoma, Follicular; Adrenal Cortex Neoplasms; Anus Neoplasms; Appendiceal Neoplasms; Ependymoma; Esophageal Neoplasms; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Hodgkin Disease; Insulinoma; Lymphoma, Non-Hodgkin; Mycosis Fungoides; Oropharyngeal Neoplasms; Parathyroid Neoplasms; Pericardial Effusion; Peritoneal Neoplasms; Pleural Effusion; Skin Diseases; Somatostatinoma; Squamous Cell Carcinoma of Head and Neck; Testicular Neoplasms; Thyroid Neoplasms; Uterine Cervical Neoplasms; Vaginal Neoplasms; Vulvar Neoplasms; Adenocarcinoma; Biliary Tract Neoplasms; Carcinoma; Carcinoma, Ductal; Carcinoma, Non-Small-Cell Lung; Cholangiocarcinoma; Colorectal Neoplasms; Digestive System Neoplasms; Endometrial Neoplasms; Head and Neck Neoplasms; Hemangiosarcoma; Leukemia; Leukemia, Myeloid, Acute; Lung Neoplasms; Neoplasm Metastasis; Osteitis Deformans; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Salivary Gland Neoplasms; Sarcoma; Urethral Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Brain Diseases; Breast Neoplasms, Male; Carcinoma, Intraductal, Noninfiltrating; Inflammatory Breast Neoplasms; Stomach Neoplasms; Breast Neoplasms; Neoplasms
Receptor protein-tyrosine kinase erbB-2 inhibitor
Small molecule
Approved
CANCER; OTHER
ORAL
Carcinoma, Merkel Cell; Central Nervous System Neoplasms; Lymphoma, Non-Hodgkin; Melanoma; Neoplasm Metastasis; Urinary Bladder Neoplasms; Anus Neoplasms; Brain Neoplasms; Breast Neoplasms, Male; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Neuroendocrine; Carcinoma, Pancreatic Ductal; Fallopian Tube Neoplasms; Glioblastoma; Glioma; Head and Neck Neoplasms; Hypopharyngeal Neoplasms; Inflammatory Breast Neoplasms; Kidney Neoplasms; Lung Neoplasms; Mesothelioma; Oropharyngeal Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Skin Neoplasms; Squamous Cell Carcinoma of Head and Neck; Thyroid Neoplasms; Triple Negative Breast Neoplasms; Uterine Cervical Neoplasms; Adenocarcinoma; Biliary Tract Neoplasms; Brain Diseases; Carcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Cholangiocarcinoma; Colorectal Neoplasms; Esophageal Neoplasms; Gallbladder Neoplasms; Hand-Foot Syndrome; Liver Neoplasms; Nasopharyngeal Neoplasms; Neuroendocrine Tumors; Pancreatic Neoplasms; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Stomach Neoplasms; Breast Neoplasms; Colonic Neoplasms; Neoplasms
DNA inhibitor
Antibody
Approved
RHEUMATOLOGY
UNKNOWN
Berylliosis; Granulomatous Disease, Chronic; Arthritis, Reactive; Bipolar Disorder; Colitis; Dermatomyositis; Diabetes Mellitus, Type 1; Endometriosis; Eosinophilic Esophagitis; Giant Cell Arteritis; Granulomatosis with Polyangiitis; Hepatitis C; Hidradenitis Suppurativa; Microscopic Polyangiitis; Myelodysplastic Syndromes; Myositis; Osteoarthritis; Paraparesis, Tropical Spastic; Pemphigus; Reperfusion Injury; Spondylarthropathies; Stevens-Johnson Syndrome; Takayasu Arteritis; Wet Macular Degeneration; Anorexia; Arthritis, Juvenile; Behcet Syndrome; Cachexia; Fatigue; Graft vs Host Disease; Hepatitis C, Chronic; Inflammatory Bowel Diseases; Low Back Pain; Lung Neoplasms; Mucocutaneous Lymph Node Syndrome; Parapsoriasis; Polymyalgia Rheumatica; Pulmonary Disease, Chronic Obstructive; Sarcoidosis; Scleritis; Severe Acute Respiratory Syndrome; Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Immune System Diseases; Psoriasis; Spondylitis, Ankylosing
TNF-alpha inhibitor
Small molecule
Approved
OTHER
INTRAVESICAL
Carcinoma in Situ; Urinary Bladder Neoplasms; Carcinoma; Neoplasms
DNA inhibitor
Small molecule
Approved
Unknown
Unknown
Foramen Ovale, Patent; Migraine with Aura; Pulmonary Edema; Skin Diseases; Acute Kidney Injury; Anemia, Sickle Cell; Brain Diseases; Coronary Disease; Heart Diseases; Hepatitis C; Infertility, Female; Ischemic Stroke; Liver Cirrhosis; Lymphangioma; Mycobacterium Infections; Myelodysplastic Syndromes; Pulmonary Embolism; Severe Acute Respiratory Syndrome; Urinary Incontinence; Brain Injuries; Bronchopulmonary Dysplasia; Carcinoma, Non-Small-Cell Lung; Cerebral Small Vessel Diseases; Cystic Fibrosis; Fetal Growth Retardation; Hypoplastic Left Heart Syndrome; Infertility; Muscular Dystrophy, Duchenne; Parkinson Disease; Pre-Eclampsia; Pregnancy; Premature Birth; Priapism; Prostatic Hyperplasia; Raynaud Disease; Scleroderma, Localized; Sexual Dysfunction, Physiological; Skin Ulcer; Arterial Occlusive Diseases; Coronary Vasospasm; Diabetes Mellitus; Eisenmenger Complex; Glaucoma; Heart Failure; Hypertension; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Lung Diseases; Peripheral Arterial Disease; Persistent Fetal Circulation Syndrome; Scleroderma, Systemic; Erectile Dysfunction
Unknown
Small molecule
Approved
CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER
ORAL
Pain; Atherosclerosis; Breast Neoplasms; Coronary Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Essential Hypertension; Hypercholesterolemia; Hypertension, Renovascular; Proteinuria; Renal Artery Obstruction; Angina Pectoris; Angina, Stable; Cardiovascular Diseases; Diabetes Mellitus; Heart Failure; Hypertension; Myocardial Infarction; Stroke
Type-1 angiotensin II receptor antagonist
Protein
Approved
OTHER; RHEUMATOLOGY
SUBCUTANEOUS; UNKNOWN
Fanconi Anemia; Myositis, Inclusion Body; HIV Infections; Leukemia, Lymphocytic, Chronic, B-Cell; Myelodysplastic Syndromes; Neoplasms; Persian Gulf Syndrome; Prostatic Neoplasms, Castration-Resistant; Sciatica; Subarachnoid Hemorrhage; Alzheimer Disease; Amyloidosis; Asthma; Dermatomyositis; Granulomatosis with Polyangiitis; Hidradenitis Suppurativa; Histiocytosis; Leukemia; Lichen Planus; Lupus Erythematosus, Cutaneous; Lupus Nephritis; Metabolic Syndrome; Mucocutaneous Lymph Node Syndrome; Pemphigus; Pulmonary Disease, Chronic Obstructive; Pulmonary Fibrosis; Radiculopathy; Renal Insufficiency, Chronic; Reperfusion Injury; Sjogren's Syndrome; Stomatitis; Synovitis; Temporomandibular Joint Disorders; Tinnitus; Urticaria; Vitiligo; Anorexia; Arthritis; Cachexia; Diabetes Mellitus, Type 1; Graft vs Host Disease; Inflammation; Pneumonia; Polymyalgia Rheumatica; Stevens-Johnson Syndrome; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Immune System Diseases; Psoriasis; Spondylitis; Spondylitis, Ankylosing
TNF-alpha inhibitor
Small molecule
Approved
OTHER
ORAL
Unknown
Unknown
Protein
Approved
Unknown
INJECTION; NASAL
Common Cold; Diabetes Mellitus, Type 2; Congenital Hyperinsulinism; Nesidioblastosis; Obesity; Diabetes Mellitus, Type 1; Diabetes Mellitus; Hypoglycemia
Glucagon receptor agonist
Small molecule
Unknown
Unknown
Unknown
Autistic Disorder; Panic Disorder; Hot Flashes; Depressive Disorder; Depressive Disorder, Major
Serotonin transporter inhibitor