DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 10647


Small molecule Approved OTHER ORAL Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Breast Carcinoma In Situ; Carcinoma, Hepatocellular; Depressive Disorder, Major; Fractures, Bone; Hepatolenticular Degeneration; Hypotension, Orthostatic; Inflammation; Keratosis, Actinic; Mouth Neoplasms; Myositis; Neuroblastoma; Obesity; Triple Negative Breast Neoplasms; Tuberculosis; Uterine Cervical Neoplasms; Amyotrophic Lateral Sclerosis; Back Pain; Brain Neoplasms; Carcinoma, Renal Cell; Central Nervous System Neoplasms; Cerebral Hemorrhage; Endometrial Neoplasms; Esophageal Neoplasms; Facial Pain; Glioblastoma; Graves Ophthalmopathy; Hepatitis B, Chronic; Lymphangioleiomyomatosis; Medulloblastoma; Melanoma; Multiple Myeloma; Multiple Sclerosis; Muscular Atrophy, Spinal; Neuralgia; Neurofibromatosis 1; Obsessive-Compulsive Disorder; Ovarian Neoplasms; Papilloma; Paraganglioma; Paraproteinemias; Peritoneal Neoplasms; Post-Acute COVID-19 Syndrome; Pre-Eclampsia; Prostatic Hyperplasia; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rotator Cuff Injuries; Sarcoma; Schizophrenia; Severe Acute Respiratory Syndrome; Squamous Cell Carcinoma of Head and Neck; Squamous Intraepithelial Lesions; Stomatitis; Temporomandibular Joint Disorders; Tonsillitis; Toothache; Urinary Bladder Neoplasms; Uterine Cervical Dysplasia; Uterine Neoplasms; Adenoma; Alzheimer Disease; Bipolar Disorder; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Chronic Pain; Colonic Neoplasms; Colorectal Neoplasms; Depression, Postpartum; Depressive Disorder; Gout; Hand-Foot Syndrome; Head and Neck Neoplasms; Hypertension; Influenza, Human; Liver Neoplasms; Low Back Pain; Lung Neoplasms; Macular Degeneration; Memory Disorders; Nasopharyngeal Carcinoma; Osteoarthritis, Hip; Osteoarthritis, Knee; Pancreatic Neoplasms; Pharyngitis; Rectal Neoplasms; Thyroiditis, Subacute; Tobacco Use Disorder; Wounds and Injuries; Acute Pain; Adenomatous Polyposis Coli; Arthritis, Juvenile; Arthritis, Rheumatoid; Dysmenorrhea; Hemorrhage; Migraine Disorders; Neoplasms; Osteoarthritis; Pain; Peptic Ulcer; Rheumatic Diseases; Spondylitis; Spondylitis, Ankylosing; Stroke Cyclooxygenase-2 inhibitor

Small molecule

Approved

OTHER

ORAL

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Breast Carcinoma In Situ; Carcinoma, Hepatocellular; Depressive Disorder, Major; Fractures, Bone; Hepatolenticular Degeneration; Hypotension, Orthostatic; Inflammation; Keratosis, Actinic; Mouth Neoplasms; Myositis; Neuroblastoma; Obesity; Triple Negative Breast Neoplasms; Tuberculosis; Uterine Cervical Neoplasms; Amyotrophic Lateral Sclerosis; Back Pain; Brain Neoplasms; Carcinoma, Renal Cell; Central Nervous System Neoplasms; Cerebral Hemorrhage; Endometrial Neoplasms; Esophageal Neoplasms; Facial Pain; Glioblastoma; Graves Ophthalmopathy; Hepatitis B, Chronic; Lymphangioleiomyomatosis; Medulloblastoma; Melanoma; Multiple Myeloma; Multiple Sclerosis; Muscular Atrophy, Spinal; Neuralgia; Neurofibromatosis 1; Obsessive-Compulsive Disorder; Ovarian Neoplasms; Papilloma; Paraganglioma; Paraproteinemias; Peritoneal Neoplasms; Post-Acute COVID-19 Syndrome; Pre-Eclampsia; Prostatic Hyperplasia; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rotator Cuff Injuries; Sarcoma; Schizophrenia; Severe Acute Respiratory Syndrome; Squamous Cell Carcinoma of Head and Neck; Squamous Intraepithelial Lesions; Stomatitis; Temporomandibular Joint Disorders; Tonsillitis; Toothache; Urinary Bladder Neoplasms; Uterine Cervical Dysplasia; Uterine Neoplasms; Adenoma; Alzheimer Disease; Bipolar Disorder; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Chronic Pain; Colonic Neoplasms; Colorectal Neoplasms; Depression, Postpartum; Depressive Disorder; Gout; Hand-Foot Syndrome; Head and Neck Neoplasms; Hypertension; Influenza, Human; Liver Neoplasms; Low Back Pain; Lung Neoplasms; Macular Degeneration; Memory Disorders; Nasopharyngeal Carcinoma; Osteoarthritis, Hip; Osteoarthritis, Knee; Pancreatic Neoplasms; Pharyngitis; Rectal Neoplasms; Thyroiditis, Subacute; Tobacco Use Disorder; Wounds and Injuries; Acute Pain; Adenomatous Polyposis Coli; Arthritis, Juvenile; Arthritis, Rheumatoid; Dysmenorrhea; Hemorrhage; Migraine Disorders; Neoplasms; Osteoarthritis; Pain; Peptic Ulcer; Rheumatic Diseases; Spondylitis; Spondylitis, Ankylosing; Stroke

Cyclooxygenase-2 inhibitor


Protein Approved Unknown Unknown Anemia, Sickle Cell; Brain Infarction; Coronary Disease; Pneumonia; Shock, Septic; ST Elevation Myocardial Infarction; Stroke; Cardiovascular Diseases; Ischemic Stroke; Myocardial Ischemia; Acute Coronary Syndrome; Angina, Unstable; Myocardial Infarction; Thrombosis Integrin alpha-IIb/beta-3 inhibitor


Small molecule Approved OTHER OPHTHALMIC Central Serous Chorioretinopathy; Glaucoma; Glaucoma, Open-Angle; Ocular Hypertension Carbonic anhydrase II inhibitor


Small molecule Approved Unknown Unknown Glioma; Hepatitis C; Acidosis, Lactic; Lipodystrophy; Sarcoma, Kaposi; Acquired Immunodeficiency Syndrome; HIV Infections; Tuberculosis; Virus Diseases Unknown


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER; UROLOGY AND KIDNEY INJECTION; INTRAVENOUS; ORAL Breast Neoplasms; Multiple Myeloma; Neoplasms; Neoplasms, Plasma Cell; Pancreatitis, Chronic; Carcinoma, Pancreatic Ductal; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Hypocalcemia; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Albuminuria; Glomerulonephritis, IGA; Hyperparathyroidism; Hypertrophy, Left Ventricular; Kidney Diseases; Proteinuria; Hyperparathyroidism, Secondary; Parathyroid Diseases; Renal Insufficiency, Chronic Vitamin D receptor agonist

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER; UROLOGY AND KIDNEY

INJECTION; INTRAVENOUS; ORAL

Breast Neoplasms; Multiple Myeloma; Neoplasms; Neoplasms, Plasma Cell; Pancreatitis, Chronic; Carcinoma, Pancreatic Ductal; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Hypocalcemia; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Albuminuria; Glomerulonephritis, IGA; Hyperparathyroidism; Hypertrophy, Left Ventricular; Kidney Diseases; Proteinuria; Hyperparathyroidism, Secondary; Parathyroid Diseases; Renal Insufficiency, Chronic

Vitamin D receptor agonist


Oligonucleotide Approved EYE INJECTION Cytomegalovirus Retinitis Major intermediate early region 2 mRNA antisense inhibitor


Antibody Approved OTHER; RESPIRATORY UNKNOWN Hernias, Diaphragmatic, Congenital; Bronchopulmonary Dysplasia; Respiratory Syncytial Virus Infections; Respiratory Tract Diseases Fusion glycoprotein F0 inhibitor


Small molecule Approved Unknown Unknown Headache; Migraine Disorders Unknown


Small molecule Approved OTHER INTRAVESICAL Carcinoma in Situ; Urinary Bladder Neoplasms; Carcinoma; Neoplasms DNA inhibitor


Small molecule Approved OTHER; PREGNANCY AND GYNECOLOGY ORAL Prostatic Neoplasms, Castration-Resistant; Sleep Apnea, Obstructive; Alzheimer Disease; HIV Infections; Neuralgia; Albuminuria; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Essential Hypertension; Heart Diseases; Kidney Diseases; Kidney Failure, Chronic; Lipid Metabolism Disorders; Polycystic Kidney Diseases; Severe Acute Respiratory Syndrome; Cardiovascular Diseases; Diabetes Mellitus; Hypertension; Myocardial Infarction; Stroke Type-1 angiotensin II receptor antagonist

Small molecule

Approved

OTHER; PREGNANCY AND GYNECOLOGY

ORAL

Prostatic Neoplasms, Castration-Resistant; Sleep Apnea, Obstructive; Alzheimer Disease; HIV Infections; Neuralgia; Albuminuria; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Essential Hypertension; Heart Diseases; Kidney Diseases; Kidney Failure, Chronic; Lipid Metabolism Disorders; Polycystic Kidney Diseases; Severe Acute Respiratory Syndrome; Cardiovascular Diseases; Diabetes Mellitus; Hypertension; Myocardial Infarction; Stroke

Type-1 angiotensin II receptor antagonist


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER; RHEUMATOLOGY ORAL Breast Diseases; Breast Neoplasms; Bronchiolitis Obliterans Syndrome; Hemosiderosis; HIV Infections; Melanoma; Neoplasms; IgA Vasculitis; Lupus Erythematosus, Systemic; Lymphoproliferative Disorders; Multiple Myeloma; Pemphigoid, Bullous; Prostatic Neoplasms, Castration-Resistant; Sjogren's Syndrome; Smoldering Multiple Myeloma; Uveitis; Central Nervous System Neoplasms; Lupus Nephritis; Myasthenia Gravis; Polymyalgia Rheumatica; Severe Acute Respiratory Syndrome; Arthritis, Psoriatic; Arthritis, Rheumatoid Dihydroorotate dehydrogenase inhibitor

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER; RHEUMATOLOGY

ORAL

Breast Diseases; Breast Neoplasms; Bronchiolitis Obliterans Syndrome; Hemosiderosis; HIV Infections; Melanoma; Neoplasms; IgA Vasculitis; Lupus Erythematosus, Systemic; Lymphoproliferative Disorders; Multiple Myeloma; Pemphigoid, Bullous; Prostatic Neoplasms, Castration-Resistant; Sjogren's Syndrome; Smoldering Multiple Myeloma; Uveitis; Central Nervous System Neoplasms; Lupus Nephritis; Myasthenia Gravis; Polymyalgia Rheumatica; Severe Acute Respiratory Syndrome; Arthritis, Psoriatic; Arthritis, Rheumatoid

Dihydroorotate dehydrogenase inhibitor


Small molecule Approved Unknown Unknown Chronic Kidney Disease-Mineral and Bone Disorder; Fibrous Dysplasia of Bone; Lung Neoplasms; Menopause; Back Pain; Bone Diseases, Metabolic; Osteitis Deformans; Osteoporosis; Osteoporosis, Postmenopausal; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Spinal Cord Injuries; Bone Diseases Unknown


Small molecule Approved Unknown Unknown Neuralgia; Kidney Calculi; Low Back Pain; Pain; Pelvic Organ Prolapse; Urinary Bladder, Overactive; Polyuria; Urinary Incontinence Unknown


Protein Approved Unknown Unknown Adenocarcinoma, Follicular; Goiter, Nodular; Graves Disease; Thyroid Neoplasms Thyroid stimulating hormone receptor agonist


Small molecule Approved Unknown Unknown Acute Coronary Syndrome; Child Development Disorders, Pervasive; Alcoholism; Bipolar Disorder; Cocaine-Related Disorders; Irritable Bowel Syndrome; Opioid-Related Disorders; Panic Disorder; Parkinson Disease; Anxiety; Burning Mouth Syndrome; Dementia; Obsessive-Compulsive Disorder; Psychomotor Agitation; Schizophrenia; Stroke; Depressive Disorder; Depressive Disorder, Major Unknown

Small molecule

Approved

Unknown

Acute Coronary Syndrome; Child Development Disorders, Pervasive; Alcoholism; Bipolar Disorder; Cocaine-Related Disorders; Irritable Bowel Syndrome; Opioid-Related Disorders; Panic Disorder; Parkinson Disease; Anxiety; Burning Mouth Syndrome; Dementia; Obsessive-Compulsive Disorder; Psychomotor Agitation; Schizophrenia; Stroke; Depressive Disorder; Depressive Disorder, Major

Unknown


Small molecule Approved OTHER ORAL Cognitive Dysfunction; Hypotension, Orthostatic; Low Back Pain; Melanoma; Psychotic Disorders; Sleep Apnea Syndromes; Sleep Initiation and Maintenance Disorders; Tinnitus; Tobacco Use Disorder; Alcoholism; Amphetamine-Related Disorders; Cognition; Deglutition Disorders; Depressive Disorder; Opioid-Related Disorders; Ovarian Neoplasms; Parkinson Disease; Schizophrenia; Stress Disorders, Post-Traumatic; Substance-Related Disorders; Alzheimer Disease; Brain Neoplasms; Cocaine-Related Disorders; Depressive Disorder, Major; Fatigue; Multiple Sclerosis; Postpoliomyelitis Syndrome; Sarcoma, Ewing; Sleep Wake Disorders; Stroke; Attention Deficit Disorder with Hyperactivity; Narcolepsy; Sleep Apnea, Obstructive Dopamine transporter inhibitor

Small molecule

Approved

OTHER

ORAL

Cognitive Dysfunction; Hypotension, Orthostatic; Low Back Pain; Melanoma; Psychotic Disorders; Sleep Apnea Syndromes; Sleep Initiation and Maintenance Disorders; Tinnitus; Tobacco Use Disorder; Alcoholism; Amphetamine-Related Disorders; Cognition; Deglutition Disorders; Depressive Disorder; Opioid-Related Disorders; Ovarian Neoplasms; Parkinson Disease; Schizophrenia; Stress Disorders, Post-Traumatic; Substance-Related Disorders; Alzheimer Disease; Brain Neoplasms; Cocaine-Related Disorders; Depressive Disorder, Major; Fatigue; Multiple Sclerosis; Postpoliomyelitis Syndrome; Sarcoma, Ewing; Sleep Wake Disorders; Stroke; Attention Deficit Disorder with Hyperactivity; Narcolepsy; Sleep Apnea, Obstructive

Dopamine transporter inhibitor


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Amyloid Neuropathies, Familial; Cocaine-Related Disorders; Executive Function; Neuroblastoma; Alcoholism; Brain Injuries; Gambling; Obsessive-Compulsive Disorder; Pick Disease of the Brain; Schizophrenia; Tobacco Use Disorder; Liver Failure; Parkinson Disease Catechol O-methyltransferase inhibitor


Small molecule Approved RESPIRATORY ORAL Osteomyelitis; HIV Infections; Tuberculosis, Pulmonary; Tuberculosis Bacterial DNA-directed RNA polymerase inhibitor


Protein Approved Unknown Unknown Lung Neoplasms; Thrombocytopenia; Thromboembolism; Thrombosis Thrombin inhibitor


Unknown Approved OTHER INTRATRACHEAL Acute Lung Injury; Bronchopulmonary Dysplasia; Respiratory Distress Syndrome; Respiratory Distress Syndrome, Newborn Surfactant agent


Small molecule Approved DERMATOLOGY; OTHER ORAL Amyloidosis; Endometriosis; Epilepsy; Scleroderma, Systemic; Acquired Immunodeficiency Syndrome; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Appendiceal Neoplasms; Brain Stem Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Castleman Disease; Central Nervous System Neoplasms; Cholangitis, Sclerosing; Colonic Neoplasms; Esophageal Neoplasms; Glioblastoma; Head and Neck Neoplasms; Hepatitis C; Histiocytosis, Langerhans-Cell; HIV Infections; HIV Wasting Syndrome; Hodgkin Disease; Immunoglobulin Light-chain Amyloidosis; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Liver Neoplasms; Lupus Erythematosus, Discoid; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Medulloblastoma; Melanoma; Mouth Neoplasms; Neuroblastoma; Neuroendocrine Tumors; Ovarian Neoplasms; Pain; Pancreatitis, Chronic; Paraganglioma; Primary Myelofibrosis; Proctitis; Prostatic Neoplasms; Psoriasis; Purpura, Thrombocytopenic, Idiopathic; Retroviridae Infections; Sarcoma; Severe Acute Respiratory Syndrome; Spondylitis, Ankylosing; Syringomyelia; Thalassemia; Uveal Melanoma; Waldenstrom Macroglobulinemia; Amyloidosis, Familial; beta-Thalassemia; Carcinoma, Hepatocellular; Carcinoma, Ovarian Epithelial; Colitis, Ulcerative; Colorectal Neoplasms; Cough; Crohn Disease; Fallopian Tube Neoplasms; Granuloma, Lethal Midline; Hypoalbuminemia; Idiopathic Pulmonary Fibrosis; Kidney Neoplasms; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Myelodysplastic Syndromes; Neoplasms; Neoplasms, Plasma Cell; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoidosis; Stomatitis; Vascular Malformations; Immune System Diseases; Multiple Myeloma CRL4(CRBN) E3 ubiquitin ligase inhibitor

Small molecule

Approved

DERMATOLOGY; OTHER

ORAL

Amyloidosis; Endometriosis; Epilepsy; Scleroderma, Systemic; Acquired Immunodeficiency Syndrome; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Appendiceal Neoplasms; Brain Stem Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Castleman Disease; Central Nervous System Neoplasms; Cholangitis, Sclerosing; Colonic Neoplasms; Esophageal Neoplasms; Glioblastoma; Head and Neck Neoplasms; Hepatitis C; Histiocytosis, Langerhans-Cell; HIV Infections; HIV Wasting Syndrome; Hodgkin Disease; Immunoglobulin Light-chain Amyloidosis; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Liver Neoplasms; Lupus Erythematosus, Discoid; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Medulloblastoma; Melanoma; Mouth Neoplasms; Neuroblastoma; Neuroendocrine Tumors; Ovarian Neoplasms; Pain; Pancreatitis, Chronic; Paraganglioma; Primary Myelofibrosis; Proctitis; Prostatic Neoplasms; Psoriasis; Purpura, Thrombocytopenic, Idiopathic; Retroviridae Infections; Sarcoma; Severe Acute Respiratory Syndrome; Spondylitis, Ankylosing; Syringomyelia; Thalassemia; Uveal Melanoma; Waldenstrom Macroglobulinemia; Amyloidosis, Familial; beta-Thalassemia; Carcinoma, Hepatocellular; Carcinoma, Ovarian Epithelial; Colitis, Ulcerative; Colorectal Neoplasms; Cough; Crohn Disease; Fallopian Tube Neoplasms; Granuloma, Lethal Midline; Hypoalbuminemia; Idiopathic Pulmonary Fibrosis; Kidney Neoplasms; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Myelodysplastic Syndromes; Neoplasms; Neoplasms, Plasma Cell; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoidosis; Stomatitis; Vascular Malformations; Immune System Diseases; Multiple Myeloma

CRL4(CRBN) E3 ubiquitin ligase inhibitor


Small molecule Approved Unknown Unknown Migraine with Aura; Migraine without Aura; Migraine Disorders Unknown


Antibody Approved DIABETES DRUGS & ENDOCRINOLOGY; IMMUNE SYSTEM; OTHER SINGLE-USE DiGeorge Syndrome; Kidney Tubular Necrosis, Acute; Leukemia, Myeloid, Acute; Multiple Myeloma; Neoplasms; Uremia; Amyotrophic Lateral Sclerosis; Colitis, Ulcerative; Glioblastoma; Glomerulosclerosis, Focal Segmental; Granuloma, Lethal Midline; Hodgkin Disease; Kidney Diseases; Renal Insufficiency, Chronic; Uveitis; Diabetes Mellitus, Type 1; Emphysema; Graft vs Host Disease; Infections; Reperfusion Injury; Delayed Graft Function; Immune System Diseases; Kidney Transplantation Interleukin-2 receptor inhibitor

Antibody

Approved

DIABETES DRUGS & ENDOCRINOLOGY; IMMUNE SYSTEM; OTHER

SINGLE-USE

DiGeorge Syndrome; Kidney Tubular Necrosis, Acute; Leukemia, Myeloid, Acute; Multiple Myeloma; Neoplasms; Uremia; Amyotrophic Lateral Sclerosis; Colitis, Ulcerative; Glioblastoma; Glomerulosclerosis, Focal Segmental; Granuloma, Lethal Midline; Hodgkin Disease; Kidney Diseases; Renal Insufficiency, Chronic; Uveitis; Diabetes Mellitus, Type 1; Emphysema; Graft vs Host Disease; Infections; Reperfusion Injury; Delayed Graft Function; Immune System Diseases; Kidney Transplantation

Interleukin-2 receptor inhibitor


Small molecule Approved Unknown Unknown Bronchopulmonary Dysplasia; HIV Infections; Immune System Diseases; Non-alcoholic Fatty Liver Disease; Persian Gulf Syndrome; Respiratory Tract Diseases; Alzheimer Disease; Anemia, Sickle Cell; Carcinoma, Non-Small-Cell Lung; Cough; Parkinson Disease; Premature Birth; Severe Dengue; Sleep Apnea Syndromes; Status Asthmaticus; Acne Vulgaris; Arthritis, Rheumatoid; Diabetic Nephropathies; Eosinophilic Esophagitis; Multiple Myeloma; Pain; Respiratory Sounds; Rhinitis, Allergic, Perennial; Severe Acute Respiratory Syndrome; Sleep Apnea, Obstructive; Asthma; Asthma, Exercise-Induced; Lung Diseases, Obstructive; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal Unknown

Small molecule

Approved

Unknown

Bronchopulmonary Dysplasia; HIV Infections; Immune System Diseases; Non-alcoholic Fatty Liver Disease; Persian Gulf Syndrome; Respiratory Tract Diseases; Alzheimer Disease; Anemia, Sickle Cell; Carcinoma, Non-Small-Cell Lung; Cough; Parkinson Disease; Premature Birth; Severe Dengue; Sleep Apnea Syndromes; Status Asthmaticus; Acne Vulgaris; Arthritis, Rheumatoid; Diabetic Nephropathies; Eosinophilic Esophagitis; Multiple Myeloma; Pain; Respiratory Sounds; Rhinitis, Allergic, Perennial; Severe Acute Respiratory Syndrome; Sleep Apnea, Obstructive; Asthma; Asthma, Exercise-Induced; Lung Diseases, Obstructive; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal

Unknown


Small molecule Approved IMMUNE SYSTEM; OTHER ORAL Diabetes Mellitus, Type 2; Hepatitis C; Lymphoma, Non-Hodgkin; Malaria; Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Triple Negative Breast Neoplasms; Acquired Immunodeficiency Syndrome; Tuberculosis; Autoimmune Diseases; HIV Infections; Infections; Virus Diseases Human immunodeficiency virus type 1 reverse transcriptase inhibitor

Small molecule

Approved

IMMUNE SYSTEM; OTHER

ORAL

Diabetes Mellitus, Type 2; Hepatitis C; Lymphoma, Non-Hodgkin; Malaria; Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Triple Negative Breast Neoplasms; Acquired Immunodeficiency Syndrome; Tuberculosis; Autoimmune Diseases; HIV Infections; Infections; Virus Diseases

Human immunodeficiency virus type 1 reverse transcriptase inhibitor

Antibody

Approved

PREGNANCY AND GYNECOLOGY

INTRAVENOUS

Adenocarcinoma, Follicular; Adrenal Cortex Neoplasms; Anus Neoplasms; Appendiceal Neoplasms; Breast Diseases; Carcinoid Tumor; Carcinoma, Ovarian Epithelial; Carcinoma, Renal Cell; Ependymoma; Fallopian Tube Neoplasms; Hodgkin Disease; Insulinoma; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous; Mycosis Fungoides; Oropharyngeal Neoplasms; Parathyroid Neoplasms; Pericardial Effusion; Peritoneal Neoplasms; Pleural Effusion; Skin Diseases; Somatostatinoma; Testicular Neoplasms; Thyroid Neoplasms; Uterine Cervical Neoplasms; Vaginal Neoplasms; Vulvar Neoplasms; Adenocarcinoma; Bile Duct Neoplasms; Carcinoma; Carcinoma, Ductal; Carcinoma, Non-Small-Cell Lung; Cholangiocarcinoma; Colonic Neoplasms; Digestive System Neoplasms; Endometrial Neoplasms; Gallbladder Neoplasms; Head and Neck Neoplasms; Hemangiosarcoma; Hematologic Neoplasms; Leukemia; Leukemia, Myeloid, Acute; Lung Neoplasms; Neoplasm Metastasis; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Salivary Gland Neoplasms; Sarcoma; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Biliary Tract Neoplasms; Brain Diseases; Breast Neoplasms, Male; Carcinoma, Intraductal, Noninfiltrating; Colorectal Neoplasms; Esophageal Neoplasms; Inflammatory Breast Neoplasms; Breast Neoplasms; Neoplasms; Stomach Neoplasms

Receptor protein-tyrosine kinase erbB-2 inhibitor

Small molecule

Approved

CANCER; OTHER

ORAL

Carcinoma, Merkel Cell; Central Nervous System Neoplasms; Lymphoma, Non-Hodgkin; Melanoma; Neoplasm Metastasis; Urinary Bladder Neoplasms; Anus Neoplasms; Bile Duct Neoplasms; Brain Neoplasms; Breast Neoplasms, Male; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Neuroendocrine; Fallopian Tube Neoplasms; Glioblastoma; Glioma; Head and Neck Neoplasms; Hypopharyngeal Neoplasms; Inflammatory Breast Neoplasms; Kidney Neoplasms; Lung Neoplasms; Mesothelioma; Oropharyngeal Neoplasms; Ovarian Neoplasms; Paraganglioma; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pseudomyxoma Peritonei; Skin Neoplasms; Squamous Cell Carcinoma of Head and Neck; Thyroid Neoplasms; Uterine Cervical Neoplasms; Adenocarcinoma; Biliary Tract Neoplasms; Brain Diseases; Carcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Cholangiocarcinoma; Esophageal Neoplasms; Gallbladder Neoplasms; Hand-Foot Syndrome; Liver Neoplasms; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neuroendocrine Tumors; Pancreatic Neoplasms; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Triple Negative Breast Neoplasms; Breast Neoplasms; Colonic Neoplasms; Colorectal Neoplasms; Neoplasms; Stomach Neoplasms

DNA inhibitor


Small molecule Approved Unknown Unknown Autistic Disorder; Panic Disorder; Hot Flashes; Depressive Disorder; Depressive Disorder, Major Serotonin transporter inhibitor

Antibody

Approved

RHEUMATOLOGY

UNKNOWN

Berylliosis; Glaucoma; Granulomatous Disease, Chronic; Arthritis, Reactive; Bipolar Disorder; Choroidal Neovascularization; Dermatomyositis; Diabetes Mellitus, Type 1; Endometriosis; Eosinophilic Esophagitis; Giant Cell Arteritis; Granulomatosis with Polyangiitis; Hepatitis C; Hidradenitis Suppurativa; Macular Degeneration; Melanoma; Microscopic Polyangiitis; Myelodysplastic Syndromes; Myositis; Osteoarthritis; Paraparesis, Tropical Spastic; Pemphigus; Polymyositis; Reperfusion Injury; Spondylarthropathies; Stevens-Johnson Syndrome; Takayasu Arteritis; Anorexia; Arthritis, Juvenile; Behcet Syndrome; Cachexia; Colitis; Fatigue; Graft vs Host Disease; Hepatitis C, Chronic; Inflammatory Bowel Diseases; Low Back Pain; Lung Neoplasms; Mucocutaneous Lymph Node Syndrome; Parapsoriasis; Polymyalgia Rheumatica; Pulmonary Disease, Chronic Obstructive; Sarcoidosis; Scleritis; Severe Acute Respiratory Syndrome; Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Immune System Diseases; Psoriasis; Spondylitis, Ankylosing

TNF-alpha inhibitor

Small molecule

Approved

Unknown

Acute Kidney Injury; Anemia, Sickle Cell; Coronary Disease; Foramen Ovale, Patent; Heart Diseases; Hepatitis C; Hypoxia-Ischemia, Brain; Infertility, Female; Ischemic Stroke; Liver Cirrhosis; Lymphangioma; Migraine with Aura; Mycobacterium Infections; Myelodysplastic Syndromes; Pulmonary Edema; Pulmonary Embolism; Severe Acute Respiratory Syndrome; Skin Diseases; Urinary Incontinence; Brain Diseases; Brain Injuries; Bronchopulmonary Dysplasia; Carcinoma, Non-Small-Cell Lung; Cerebral Small Vessel Diseases; Cystic Fibrosis; Fetal Growth Retardation; Hypoplastic Left Heart Syndrome; Infertility; Muscular Dystrophy, Duchenne; Parkinson Disease; Pre-Eclampsia; Pregnancy; Premature Birth; Premature Ejaculation; Priapism; Prostatic Hyperplasia; Raynaud Disease; Scleroderma, Localized; Sexual Dysfunction, Physiological; Skin Ulcer; Arterial Occlusive Diseases; beta-Thalassemia; Coronary Vasospasm; Diabetes Mellitus; Eisenmenger Complex; Glaucoma; Heart Failure; Hypertension; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Lung Diseases; Peripheral Arterial Disease; Persistent Fetal Circulation Syndrome; Rectal Neoplasms; Scleroderma, Systemic; Erectile Dysfunction

Unknown

Small molecule

Approved

CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER

ORAL

Cardiovascular Diseases; Brain Injuries; Pain; Severe Acute Respiratory Syndrome; Atherosclerosis; Breast Neoplasms; Coronary Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Essential Hypertension; Hypercholesterolemia; Hypertension, Renovascular; Proteinuria; Renal Artery Obstruction; Angina Pectoris; Diabetes Mellitus; Heart Failure; Hypertension; Myocardial Infarction; Stroke

Type-1 angiotensin II receptor antagonist


Protein Approved Unknown INJECTION; NASAL Common Cold; Diabetes Mellitus, Type 2; Short Bowel Syndrome; Congenital Hyperinsulinism; Nesidioblastosis; Obesity; Diabetes Mellitus, Type 1; Diabetes Mellitus; Hypoglycemia Glucagon receptor agonist


Small molecule Approved OTHER ORAL Unknown Unknown


Protein Approved Unknown Unknown Unknown Diagnostic agent

Protein

Approved

OTHER; RHEUMATOLOGY

SUBCUTANEOUS; UNKNOWN

Fanconi Anemia; HIV Infections; Leukemia, Lymphocytic, Chronic, B-Cell; Myelodysplastic Syndromes; Myositis, Inclusion Body; Neoplasms; Persian Gulf Syndrome; Prostatic Neoplasms, Castration-Resistant; Sciatica; Subarachnoid Hemorrhage; Acquired Hyperostosis Syndrome; Alzheimer Disease; Asthma; Chronic Urticaria; Dermatomyositis; Graft vs Host Disease; Granulomatosis with Polyangiitis; Hidradenitis Suppurativa; Histiocytosis; Immunoglobulin Light-chain Amyloidosis; Leukemia; Lichen Planus; Lupus Erythematosus, Cutaneous; Lupus Nephritis; Metabolic Syndrome; Mucocutaneous Lymph Node Syndrome; Pemphigus; Pulmonary Disease, Chronic Obstructive; Pulmonary Fibrosis; Radiculopathy; Renal Insufficiency, Chronic; Reperfusion Injury; Sjogren's Syndrome; Stomatitis; Synovitis; Temporomandibular Joint Disorders; Tinnitus; Vitiligo; Anorexia; Arthritis; Cachexia; Diabetes Mellitus, Type 1; Inflammation; Pneumonia; Polymyalgia Rheumatica; Stevens-Johnson Syndrome; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Immune System Diseases; Psoriasis; Spondylarthropathies; Spondylitis; Spondylitis, Ankylosing

TNF-alpha inhibitor