DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 10647


Small molecule Approved HEMATOLOGY ORAL Cognitive Dysfunction; HIV Infections; Amyotrophic Lateral Sclerosis; beta-Thalassemia; Dementia; Friedreich Ataxia; Parkinson Disease; Acute Kidney Injury; Hemochromatosis; Pantothenate Kinase-Associated Neurodegeneration; Anemia, Sickle Cell; Thalassemia Unknown


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER INTRAVENOUS; ORAL Aphasia; Canavan Disease; Essential Tremor; Stroke; Alzheimer Disease; Anemia, Sickle Cell; Bipolar Disorder; Brain Neoplasms; Cocaine-Related Disorders; Cognitive Dysfunction; Dyskinesia, Drug-Induced; Epilepsy, Absence; Epilepsy, Reflex; Glioblastoma; Glioma; Leukemia, Myeloid, Acute; Neuralgia, Postherpetic; Neuroblastoma; Obsessive-Compulsive Disorder; Opioid-Related Disorders; Parkinson Disease; Polyneuropathies; Psychotic Disorders; Restless Legs Syndrome; Stress Disorders, Post-Traumatic; Torticollis; Alcoholism; Anxiety; Dementia; Depressive Disorder; Epilepsies, Partial; Movement Disorders; Panic Disorder; Schizophrenia; Status Epilepticus; Subarachnoid Hemorrhage; Substance Withdrawal Syndrome; Epilepsy; Epilepsy, Tonic-Clonic; Seizures Synaptic vesicle glycoprotein 2A modulator

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER

INTRAVENOUS; ORAL

Aphasia; Canavan Disease; Essential Tremor; Stroke; Alzheimer Disease; Anemia, Sickle Cell; Bipolar Disorder; Brain Neoplasms; Cocaine-Related Disorders; Cognitive Dysfunction; Dyskinesia, Drug-Induced; Epilepsy, Absence; Epilepsy, Reflex; Glioblastoma; Glioma; Leukemia, Myeloid, Acute; Neuralgia, Postherpetic; Neuroblastoma; Obsessive-Compulsive Disorder; Opioid-Related Disorders; Parkinson Disease; Polyneuropathies; Psychotic Disorders; Restless Legs Syndrome; Stress Disorders, Post-Traumatic; Torticollis; Alcoholism; Anxiety; Dementia; Depressive Disorder; Epilepsies, Partial; Movement Disorders; Panic Disorder; Schizophrenia; Status Epilepticus; Subarachnoid Hemorrhage; Substance Withdrawal Syndrome; Epilepsy; Epilepsy, Tonic-Clonic; Seizures

Synaptic vesicle glycoprotein 2A modulator


Small molecule Approved IMMUNE SYSTEM TOPICAL Breast Neoplasms; Lichen Planus; Lupus Erythematosus, Cutaneous; Psoriasis; Hand Dermatoses; Eczema; Neoplasms Retinoid receptor agonist


Small molecule Approved Unknown Unknown Obesity; Renal Insufficiency, Chronic; Infections; Influenza in Birds; Thrombocytopenia; Influenza, Human; Purpura, Thrombocytopenic, Idiopathic; Severe Acute Respiratory Syndrome; Virus Diseases Unknown


Small molecule Approved Unknown Unknown Osteomyelitis; Acquired Immunodeficiency Syndrome; Acute Coronary Syndrome; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Anemia; Arthritis, Rheumatoid; Asthma; Carcinoma, Renal Cell; Cardiotoxicity; Constipation; Coronary Disease; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dyspepsia; Epilepsy; Erectile Dysfunction; Fibromyalgia; Heart Failure; Hepatitis C; HIV Infections; Hypertension; Hypoglycemia; Hypotension, Orthostatic; Immune System Diseases; Influenza, Human; Lice Infestations; Lipid Metabolism Disorders; Lung Diseases; Lupus Erythematosus, Systemic; Lymphoma; Malaria, Vivax; Nausea; Pain; Phenylketonurias; Premature Birth; Psychotic Disorders; Respiratory Tract Infections; Restless Legs Syndrome; Schizophrenia; Cholangitis; Meningitis; Muscle Spasticity; Neoplasms; Parkinson Disease; Tuberculosis, Multidrug-Resistant; Abscess; Breast Neoplasms; Bronchitis, Chronic; Cataract; Cellulitis; Cholecystitis, Acute; Conjunctivitis, Bacterial; Endophthalmitis; Infections; Inflammation; Otitis Externa; Otitis Media; Pelvic Inflammatory Disease; Pneumonia; Pneumonia, Bacterial; Pulmonary Disease, Chronic Obstructive; Sinusitis; Skin Diseases; Tuberculosis; Tuberculosis, Pulmonary; Bacterial Infections; Eye Infections Unknown

Small molecule

Approved

Unknown

Osteomyelitis; Acquired Immunodeficiency Syndrome; Acute Coronary Syndrome; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Anemia; Arthritis, Rheumatoid; Asthma; Carcinoma, Renal Cell; Cardiotoxicity; Constipation; Coronary Disease; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dyspepsia; Epilepsy; Erectile Dysfunction; Fibromyalgia; Heart Failure; Hepatitis C; HIV Infections; Hypertension; Hypoglycemia; Hypotension, Orthostatic; Immune System Diseases; Influenza, Human; Lice Infestations; Lipid Metabolism Disorders; Lung Diseases; Lupus Erythematosus, Systemic; Lymphoma; Malaria, Vivax; Nausea; Pain; Phenylketonurias; Premature Birth; Psychotic Disorders; Respiratory Tract Infections; Restless Legs Syndrome; Schizophrenia; Cholangitis; Meningitis; Muscle Spasticity; Neoplasms; Parkinson Disease; Tuberculosis, Multidrug-Resistant; Abscess; Breast Neoplasms; Bronchitis, Chronic; Cataract; Cellulitis; Cholecystitis, Acute; Conjunctivitis, Bacterial; Endophthalmitis; Infections; Inflammation; Otitis Externa; Otitis Media; Pelvic Inflammatory Disease; Pneumonia; Pneumonia, Bacterial; Pulmonary Disease, Chronic Obstructive; Sinusitis; Skin Diseases; Tuberculosis; Tuberculosis, Pulmonary; Bacterial Infections; Eye Infections

Unknown


Small molecule Approved OTHER ORAL Metabolic Syndrome; Hyperlipoproteinemia Type I; Polycystic Ovary Syndrome; Infertility; Obesity Gastric lipase inhibitor


Small molecule Approved Unknown Unknown Carcinoma, Non-Small-Cell Lung; Esophageal Neoplasms; Hodgkin Disease; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Neoplasms, Germ Cell and Embryonal; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Testicular Neoplasms; Breast Neoplasms; Carcinoma, Hepatocellular; Inflammatory Breast Neoplasms; Lymphoma, Large B-Cell, Diffuse; Nasopharyngeal Neoplasms; Stomach Neoplasms; Thrombosis; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Neoplasms Unknown

Small molecule

Approved

Unknown

Carcinoma, Non-Small-Cell Lung; Esophageal Neoplasms; Hodgkin Disease; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Neoplasms, Germ Cell and Embryonal; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Testicular Neoplasms; Breast Neoplasms; Carcinoma, Hepatocellular; Inflammatory Breast Neoplasms; Lymphoma, Large B-Cell, Diffuse; Nasopharyngeal Neoplasms; Stomach Neoplasms; Thrombosis; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Neoplasms

Unknown


Small molecule Approved Unknown Unknown Osteomyelitis Bacterial 70S ribosome inhibitor


Small molecule Approved OTHER INJECTION Unknown Diagnostic agent


Protein Approved OTHER SINGLE-USE Psoriasis; Cystic Fibrosis; Leukemia; Lymphoma, Non-Hodgkin; Neuroblastoma; Osteosarcoma; Prostatic Neoplasms, Castration-Resistant; Retinal Degeneration; Rhabdomyosarcoma; Sarcoma, Ewing; Uveitis; Uveitis, Anterior; Xerostomia; Arthritis, Reactive; Bronchiolitis Obliterans; Fallopian Tube Neoplasms; Friedreich Ataxia; Hepatitis C, Chronic; HIV Infections; Leukocyte-Adhesion Deficiency Syndrome; Liver Cirrhosis; Meningitis, Cryptococcal; Mesothelioma; Multiple Myeloma; Mycobacterium avium-intracellulare Infection; Mycobacterium Infections; Mycosis Fungoides; Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Breast Neoplasms; Candidemia; Idiopathic Pulmonary Fibrosis; Lymphoma; Melanoma; Pulmonary Fibrosis; Granulomatous Disease, Chronic; Osteopetrosis Interferon gamma receptor agonist

Protein

Approved

OTHER

SINGLE-USE

Psoriasis; Cystic Fibrosis; Leukemia; Lymphoma, Non-Hodgkin; Neuroblastoma; Osteosarcoma; Prostatic Neoplasms, Castration-Resistant; Retinal Degeneration; Rhabdomyosarcoma; Sarcoma, Ewing; Uveitis; Uveitis, Anterior; Xerostomia; Arthritis, Reactive; Bronchiolitis Obliterans; Fallopian Tube Neoplasms; Friedreich Ataxia; Hepatitis C, Chronic; HIV Infections; Leukocyte-Adhesion Deficiency Syndrome; Liver Cirrhosis; Meningitis, Cryptococcal; Mesothelioma; Multiple Myeloma; Mycobacterium avium-intracellulare Infection; Mycobacterium Infections; Mycosis Fungoides; Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Breast Neoplasms; Candidemia; Idiopathic Pulmonary Fibrosis; Lymphoma; Melanoma; Pulmonary Fibrosis; Granulomatous Disease, Chronic; Osteopetrosis

Interferon gamma receptor agonist


Small molecule Approved Unknown Unknown Unknown Unknown


Unknown Unknown Unknown Unknown Anemia, Iron-Deficiency; Anemia Unknown


Small molecule Approved Unknown Unknown Acne Vulgaris; Astrocytoma; Colonic Neoplasms; Crohn Disease; Gliosarcoma; Oligodendroglioma; Basal Cell Nevus Syndrome; Brain Neoplasms; Carcinoma, Basal Cell; Fibromatosis, Aggressive; Glioblastoma; Neurofibromatosis 1; Glioma; Infections; Keratosis, Actinic; Neoplasms Unknown


Small molecule Unknown Unknown Unknown Pain; Pregnancy Sodium channel protein type IV alpha subunit blocker


Unknown Unknown Unknown Unknown Hypoplastic Left Heart Syndrome; Severe Acute Respiratory Syndrome; Respiratory Distress Syndrome; Respiratory Distress Syndrome, Newborn Surfactant agent


Small molecule Approved Unknown Unknown Unknown Tyrosinase inhibitor


Small molecule Approved OTHER; PHARMACOLOGY INJECTION Unknown Muscle-type nicotinic acetylcholine receptor antagonist


Small molecule Approved Unknown Unknown Brain Ischemia; Radius Fractures; Renal Insufficiency; Vascular Diseases; Alzheimer Disease; Brain Injuries; Chronic Pain; Cocaine-Related Disorders; Cognitive Dysfunction; Cough; Epilepsy; Heart Diseases; Postoperative Complications; Pregnancy; Scoliosis; Sleep Initiation and Maintenance Disorders; Acute Kidney Injury; Amyotrophic Lateral Sclerosis; Brain Neoplasms; Burns; Child Development Disorders, Pervasive; Coronary Disease; Hernias, Diaphragmatic, Congenital; Hypertension, Pulmonary; Hypertrophy; Mental Disorders; Pheochromocytoma; Pre-Eclampsia; Shoulder Pain; Temporomandibular Joint Disorders; Wounds and Injuries; Anxiety; Brain Diseases; Breast Neoplasms; Cleft Palate; Delirium; Digestive System Diseases; Fractures, Bone; Headache; Heart Septal Defects, Atrial; Hypertension; Inflammation; Neoplasms; Obesity; Obesity, Morbid; Opioid-Related Disorders; Pain; Pharyngitis; Postoperative Nausea and Vomiting; Psychomotor Agitation; Respiratory Insufficiency; Rib Fractures; Shock, Septic; Sleep Apnea, Obstructive; Stomach Neoplasms; Subarachnoid Hemorrhage; Tremor Unknown

Small molecule

Approved

Unknown

Brain Ischemia; Radius Fractures; Renal Insufficiency; Vascular Diseases; Alzheimer Disease; Brain Injuries; Chronic Pain; Cocaine-Related Disorders; Cognitive Dysfunction; Cough; Epilepsy; Heart Diseases; Postoperative Complications; Pregnancy; Scoliosis; Sleep Initiation and Maintenance Disorders; Acute Kidney Injury; Amyotrophic Lateral Sclerosis; Brain Neoplasms; Burns; Child Development Disorders, Pervasive; Coronary Disease; Hernias, Diaphragmatic, Congenital; Hypertension, Pulmonary; Hypertrophy; Mental Disorders; Pheochromocytoma; Pre-Eclampsia; Shoulder Pain; Temporomandibular Joint Disorders; Wounds and Injuries; Anxiety; Brain Diseases; Breast Neoplasms; Cleft Palate; Delirium; Digestive System Diseases; Fractures, Bone; Headache; Heart Septal Defects, Atrial; Hypertension; Inflammation; Neoplasms; Obesity; Obesity, Morbid; Opioid-Related Disorders; Pain; Pharyngitis; Postoperative Nausea and Vomiting; Psychomotor Agitation; Respiratory Insufficiency; Rib Fractures; Shock, Septic; Sleep Apnea, Obstructive; Stomach Neoplasms; Subarachnoid Hemorrhage; Tremor

Unknown


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Anxiety; Dementia; Depressive Disorder; Schizophrenia; Sleep Initiation and Maintenance Disorders GABA A receptor alpha-1/beta-1/gamma-2 positive allosteric modulator


Small molecule Approved IMMUNE SYSTEM INHALATION Dengue; Diabetes Mellitus, Type 2; Infections; Influenza, Human; Virus Diseases Neuraminidase inhibitor


Small molecule Approved Unknown Unknown Abdominal Pain; Cleft Palate; Postoperative Complications; Back Pain; Neoplasms; Pain; Pregnancy Unknown


Small molecule Approved Unknown Unknown Contracture; Peanut Hypersensitivity; Conjunctivitis, Allergic; Dyspepsia; Fibromyalgia; Rhinitis, Allergic, Perennial; Eye Manifestations; Hypersensitivity Unknown


Small molecule Approved CANCER; OTHER INTRAVENOUS; ORAL Desmoplastic Small Round Cell Tumor; Cytomegalovirus Infections; Ependymoma; Fallopian Tube Neoplasms; Meningitis, Aseptic; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Biliary Tract Neoplasms; Brain Diseases; Brain Stem Neoplasms; Breast Neoplasms; Carcinoid Tumor; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Neuroendocrine; Colorectal Neoplasms; Ganglioneuroblastoma; Gastrointestinal Stromal Tumors; Glioma; Hereditary Breast and Ovarian Cancer Syndrome; Leukemia; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma; Medulloblastoma; Myelodysplastic Syndromes; Neuroblastoma; Neuroectodermal Tumors, Primitive, Peripheral; Neurofibromatosis 1; Ovarian Neoplasms; Pancreatic Neoplasms; Pinealoma; Pituitary Neoplasms; Rectal Neoplasms; Retinoblastoma; Rhabdomyosarcoma; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Sarcoma; Skin Neoplasms; Small Cell Lung Carcinoma; Spinal Cord Neoplasms; Astrocytoma; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Choroid Plexus Neoplasms; Diffuse Intrinsic Pontine Glioma; Gliosarcoma; Melanoma; Neoplasm Metastasis; Neuroendocrine Tumors; Oligodendroglioma; Optic Nerve Glioma; Sarcoma, Ewing; Glioblastoma; Neoplasms DNA inhibitor

Small molecule

Approved

CANCER; OTHER

INTRAVENOUS; ORAL

Desmoplastic Small Round Cell Tumor; Cytomegalovirus Infections; Ependymoma; Fallopian Tube Neoplasms; Meningitis, Aseptic; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Biliary Tract Neoplasms; Brain Diseases; Brain Stem Neoplasms; Breast Neoplasms; Carcinoid Tumor; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Neuroendocrine; Colorectal Neoplasms; Ganglioneuroblastoma; Gastrointestinal Stromal Tumors; Glioma; Hereditary Breast and Ovarian Cancer Syndrome; Leukemia; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma; Medulloblastoma; Myelodysplastic Syndromes; Neuroblastoma; Neuroectodermal Tumors, Primitive, Peripheral; Neurofibromatosis 1; Ovarian Neoplasms; Pancreatic Neoplasms; Pinealoma; Pituitary Neoplasms; Rectal Neoplasms; Retinoblastoma; Rhabdomyosarcoma; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Sarcoma; Skin Neoplasms; Small Cell Lung Carcinoma; Spinal Cord Neoplasms; Astrocytoma; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Choroid Plexus Neoplasms; Diffuse Intrinsic Pontine Glioma; Gliosarcoma; Melanoma; Neoplasm Metastasis; Neuroendocrine Tumors; Oligodendroglioma; Optic Nerve Glioma; Sarcoma, Ewing; Glioblastoma; Neoplasms

DNA inhibitor


Small molecule Approved IMMUNE SYSTEM; OTHER; UROLOGY AND KIDNEY ORAL Pemphigus; Acute Lung Injury; Adenocarcinoma of Lung; Alcoholism; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Diabetic Retinopathy; Fallopian Tube Neoplasms; Fibromatosis, Aggressive; Frontotemporal Dementia; Gangliosidoses; Gaucher Disease; Glioblastoma; Glycogen Storage Disease Type II; Granulomatous Disease, Chronic; Hematologic Neoplasms; HIV Infections; Hypercholesterolemia; Hyperinsulinism; Hypertension, Pulmonary; Kidney Diseases; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Plasma Cell; Lung Neoplasms; Multiple Sclerosis, Relapsing-Remitting; Neoplasm Metastasis; Neurilemmoma; Pachyonychia Congenita; Parkinson Disease; Port-Wine Stain; Prostatic Neoplasms; Rectal Neoplasms; Respiratory Distress Syndrome; Sarcopenia; Scleritis; Small Cell Lung Carcinoma; Uveitis, Anterior; Adenomatous Polyposis Coli; Aging; Amyotrophic Lateral Sclerosis; Anemia; Anemia, Aplastic; Anemia, Sickle Cell; beta-Thalassemia; Bronchitis; Carcinoma, Renal Cell; Castleman Disease; Depressive Disorder; Dry Eye Syndromes; Fanconi Anemia; Gliosarcoma; Glomerulonephritis, IGA; Glomerulosclerosis, Focal Segmental; Graves Ophthalmopathy; Hematologic Diseases; Hypertension; Intracranial Aneurysm; Intracranial Arteriovenous Malformations; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Liver Neoplasms; Lupus Erythematosus, Systemic; Lupus Nephritis; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, T-Cell, Cutaneous; Macular Degeneration; Multiple Myeloma; Myelodysplastic Syndromes; Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuroblastoma; Neurofibromatosis 1; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Pinealoma; Polycystic Kidney Diseases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms, Castration-Resistant; Renal Insufficiency; Retroperitoneal Fibrosis; Sarcoma; Scleroderma, Systemic; Severe Acute Respiratory Syndrome; Severe Combined Immunodeficiency; Sturge-Weber Syndrome; Thyroid Neoplasms; Uveitis, Intermediate; Uveitis, Posterior; Vascular Malformations; Wet Macular Degeneration; Birt-Hogg-Dube Syndrome; Breast Neoplasms; Carcinoma, Hepatocellular; Cardiovascular Abnormalities; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Fibroma; Graft vs Host Disease; Hodgkin Disease; Lichen Planus, Oral; Lymphangioleiomyomatosis; Lymphoma, Non-Hodgkin; Myositis, Inclusion Body; Polycystic Kidney, Autosomal Dominant; Renal Insufficiency, Chronic; Skin Neoplasms; Urinary Bladder Neoplasms; Eye Diseases; Immune System Diseases FK506-binding protein 1A inhibitor

Small molecule

Approved

IMMUNE SYSTEM; OTHER; UROLOGY AND KIDNEY

ORAL

Pemphigus; Acute Lung Injury; Adenocarcinoma of Lung; Alcoholism; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Diabetic Retinopathy; Fallopian Tube Neoplasms; Fibromatosis, Aggressive; Frontotemporal Dementia; Gangliosidoses; Gaucher Disease; Glioblastoma; Glycogen Storage Disease Type II; Granulomatous Disease, Chronic; Hematologic Neoplasms; HIV Infections; Hypercholesterolemia; Hyperinsulinism; Hypertension, Pulmonary; Kidney Diseases; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Plasma Cell; Lung Neoplasms; Multiple Sclerosis, Relapsing-Remitting; Neoplasm Metastasis; Neurilemmoma; Pachyonychia Congenita; Parkinson Disease; Port-Wine Stain; Prostatic Neoplasms; Rectal Neoplasms; Respiratory Distress Syndrome; Sarcopenia; Scleritis; Small Cell Lung Carcinoma; Uveitis, Anterior; Adenomatous Polyposis Coli; Aging; Amyotrophic Lateral Sclerosis; Anemia; Anemia, Aplastic; Anemia, Sickle Cell; beta-Thalassemia; Bronchitis; Carcinoma, Renal Cell; Castleman Disease; Depressive Disorder; Dry Eye Syndromes; Fanconi Anemia; Gliosarcoma; Glomerulonephritis, IGA; Glomerulosclerosis, Focal Segmental; Graves Ophthalmopathy; Hematologic Diseases; Hypertension; Intracranial Aneurysm; Intracranial Arteriovenous Malformations; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Liver Neoplasms; Lupus Erythematosus, Systemic; Lupus Nephritis; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, T-Cell, Cutaneous; Macular Degeneration; Multiple Myeloma; Myelodysplastic Syndromes; Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuroblastoma; Neurofibromatosis 1; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Pinealoma; Polycystic Kidney Diseases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms, Castration-Resistant; Renal Insufficiency; Retroperitoneal Fibrosis; Sarcoma; Scleroderma, Systemic; Severe Acute Respiratory Syndrome; Severe Combined Immunodeficiency; Sturge-Weber Syndrome; Thyroid Neoplasms; Uveitis, Intermediate; Uveitis, Posterior; Vascular Malformations; Wet Macular Degeneration; Birt-Hogg-Dube Syndrome; Breast Neoplasms; Carcinoma, Hepatocellular; Cardiovascular Abnormalities; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Fibroma; Graft vs Host Disease; Hodgkin Disease; Lichen Planus, Oral; Lymphangioleiomyomatosis; Lymphoma, Non-Hodgkin; Myositis, Inclusion Body; Polycystic Kidney, Autosomal Dominant; Renal Insufficiency, Chronic; Skin Neoplasms; Urinary Bladder Neoplasms; Eye Diseases; Immune System Diseases

FK506-binding protein 1A inhibitor


Small molecule Approved Unknown Unknown Gastroparesis; Inflammation; Peripheral Arterial Disease; Anemia; Astrocytoma; Brain Neoplasms; Crohn Disease; Cystic Fibrosis; Diabetes Mellitus, Type 1; Glioblastoma; Granulomatous Disease, Chronic; Lupus Erythematosus, Systemic; Melanoma; Meningioma; Multiple Myeloma; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Neoplasms; Prostatic Neoplasms; Pulmonary Alveolar Proteinosis; Adrenoleukodystrophy; Alcoholism; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Asthma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiovascular Diseases; Cerebral Hemorrhage; Child Development Disorders, Pervasive; Cognitive Dysfunction; Depressive Disorder, Major; Glucose Intolerance; Hepatitis; Hepatitis C; Hepatitis C, Chronic; Hypertension, Pulmonary; Infections; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Liposarcoma; Liposarcoma, Myxoid; Lung Neoplasms; Non-alcoholic Fatty Liver Disease; Obesity; Opioid-Related Disorders; Pancreatic Neoplasms; Parkinson Disease; Polycystic Kidney Diseases; Polycystic Ovary Syndrome; Prostatic Neoplasms, Castration-Resistant; Psoriasis; Renal Insufficiency, Chronic; Stroke; Thyroid Neoplasms; Arthritis, Rheumatoid; Atherosclerosis; Coronary Disease; Diabetes Mellitus, Type 2; Fatty Liver; Friedreich Ataxia; HIV-Associated Lipodystrophy Syndrome; Hypercholesterolemia; Hypertension; Liver Diseases; Metabolic Syndrome; Diabetes Mellitus Unknown

Small molecule

Approved

Unknown

Gastroparesis; Inflammation; Peripheral Arterial Disease; Anemia; Astrocytoma; Brain Neoplasms; Crohn Disease; Cystic Fibrosis; Diabetes Mellitus, Type 1; Glioblastoma; Granulomatous Disease, Chronic; Lupus Erythematosus, Systemic; Melanoma; Meningioma; Multiple Myeloma; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Neoplasms; Prostatic Neoplasms; Pulmonary Alveolar Proteinosis; Adrenoleukodystrophy; Alcoholism; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Asthma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiovascular Diseases; Cerebral Hemorrhage; Child Development Disorders, Pervasive; Cognitive Dysfunction; Depressive Disorder, Major; Glucose Intolerance; Hepatitis; Hepatitis C; Hepatitis C, Chronic; Hypertension, Pulmonary; Infections; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Liposarcoma; Liposarcoma, Myxoid; Lung Neoplasms; Non-alcoholic Fatty Liver Disease; Obesity; Opioid-Related Disorders; Pancreatic Neoplasms; Parkinson Disease; Polycystic Kidney Diseases; Polycystic Ovary Syndrome; Prostatic Neoplasms, Castration-Resistant; Psoriasis; Renal Insufficiency, Chronic; Stroke; Thyroid Neoplasms; Arthritis, Rheumatoid; Atherosclerosis; Coronary Disease; Diabetes Mellitus, Type 2; Fatty Liver; Friedreich Ataxia; HIV-Associated Lipodystrophy Syndrome; Hypercholesterolemia; Hypertension; Liver Diseases; Metabolic Syndrome; Diabetes Mellitus

Unknown


Small molecule Approved Unknown Unknown Asthma; Pulmonary Disease, Chronic Obstructive Unknown


Small molecule Approved OTHER ORAL CADASIL; Fatty Liver; Osteoarthritis; Pain; Cerebral Small Vessel Diseases; Cognitive Dysfunction; Intermittent Claudication; Stroke; Atherosclerosis; Cardiovascular Diseases; Cerebral Infarction; Cerebrovascular Disorders; Coronary Disease; Peripheral Arterial Disease; Peripheral Vascular Diseases; Thrombosis Phosphodiesterase 3A inhibitor


Small molecule Approved Unknown Unknown Pain; Liver Diseases; Ileus; Retinopathy of Prematurity; Apnea; Premature Birth Adenosine receptor antagonist


Small molecule Approved EYE; OTHER OPHTHALMIC Chronic Pain; Conjunctivitis, Allergic; Dermatitis; Dermatitis, Atopic; Fractures, Bone; Rhinitis, Allergic, Perennial Histamine H1 receptor antagonist


Small molecule Approved OTHER; RESPIRATORY ORAL Long QT Syndrome; Heart Failure; Arrhythmias, Cardiac; Atrial Fibrillation HERG blocker

Small molecule

Approved

Unknown

Barrett Esophagus; Gingivitis; Adrenoleukodystrophy; Anemia, Sickle Cell; Burns; Carcinoma in Situ; Carcinoma, Intraductal, Noninfiltrating; Glioblastoma; Hyperlipidemias; Irritable Bowel Syndrome; Papilloma; Pneumonia; Sarcopenia; Skin Neoplasms; Tibial Fractures; Acquired Immunodeficiency Syndrome; Aging; Autistic Disorder; Bronchiolitis; Colonic Neoplasms; Common Cold; Conjunctivitis, Allergic; Depressive Disorder; Dermatitis, Atopic; Diabetes Mellitus; Diabetes Mellitus, Type 1; Glucose Intolerance; Hematologic Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Hypersensitivity; Infertility, Male; Keratosis, Actinic; Leukemia, Myeloid, Acute; Lupus Erythematosus, Systemic; Malnutrition; Metabolic Syndrome; Multiple Sclerosis; Neoplasms; Neurofibromatosis 1; Optic Neuritis; Ovarian Neoplasms; Parkinson Disease; Prediabetic State; Prostatic Neoplasms, Castration-Resistant; Psoriasis; Psychotic Disorders; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Respiratory Insufficiency; Staphylococcal Infections; Urinary Tract Infections; Adenoma; Arthritis, Juvenile; Asthma; Bone Diseases, Metabolic; Breast Neoplasms; Cardiovascular Diseases; Cognitive Dysfunction; Colitis, Ulcerative; Colorectal Neoplasms; Crohn Disease; Diabetes, Gestational; Diabetes Mellitus, Type 2; Epilepsy; Fractures, Bone; Heart Failure; Helicobacter Infections; Hepatitis C; Hip Fractures; HIV Infections; Hyperparathyroidism; Hypogonadism; Infections; Influenza, Human; Leukemia, Lymphocytic, Chronic, B-Cell; Lipid Metabolism Disorders; Melanoma; Multiple Sclerosis, Relapsing-Remitting; Non-alcoholic Fatty Liver Disease; Obesity; Osteitis Deformans; Osteoporosis, Postmenopausal; Polycystic Ovary Syndrome; Pregnancy; Prostatic Neoplasms; Renal Insufficiency, Chronic; Schizophrenia; Severe Acute Respiratory Syndrome; Tuberculosis; Tuberculosis, Pulmonary; Urticaria; Vitamin D Deficiency; Anemia; Anemia, Iron-Deficiency; Osteoporosis

Vitamin D receptor agonist


Small molecule Approved Unknown Unknown Amyotrophic Lateral Sclerosis; Communicable Diseases; Hematologic Neoplasms; Neoplasms; Dyspepsia; Duodenal Ulcer; Gastrointestinal Hemorrhage; Helicobacter Infections; Gastroesophageal Reflux; Peptic Ulcer Unknown


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL HIV Infections; Central Nervous System Neoplasms; Head and Neck Neoplasms; Heart Failure; Leukoplakia, Oral; Non-alcoholic Fatty Liver Disease; Pituitary ACTH Hypersecretion; Sarcoma; Atherosclerosis; Insulin Resistance; Diabetes Mellitus; Diabetes Mellitus, Type 2 Peroxisome proliferator-activated receptor gamma agonist


Small molecule Approved Unknown Unknown Aortic Aneurysm, Abdominal; Asthma; Muscular Dystrophy, Duchenne Unknown


Small molecule Approved Unknown Unknown Osteomyelitis Bacterial 70S ribosome inhibitor