DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 10647


Small molecule Approved OTHER ORAL Andersen Syndrome; Diabetes Mellitus, Type 1; Hypotension, Orthostatic; Melanoma; Prostatic Neoplasms, Castration-Resistant; Psychotic Disorders; Schizophrenia; Small Cell Lung Carcinoma; Chronic Pain; Cysticercosis; Helicobacter Infections; Hypertension, Pulmonary; Kidney Diseases; Landau-Kleffner Syndrome; Macular Edema; Multiple Sclerosis; Retinoschisis; Sleep Apnea, Obstructive; Status Epilepticus; Stroke; Apnea; Carcinoma, Hepatocellular; Hydrocephalus, Normal Pressure; Pseudotumor Cerebri; Altitude Sickness; Edema; Epilepsy; Glaucoma; Glaucoma, Angle-Closure; Heart Failure; Seizures Carbonic anhydrase II inhibitor

Small molecule

Approved

OTHER

ORAL

Andersen Syndrome; Diabetes Mellitus, Type 1; Hypotension, Orthostatic; Melanoma; Prostatic Neoplasms, Castration-Resistant; Psychotic Disorders; Schizophrenia; Small Cell Lung Carcinoma; Chronic Pain; Cysticercosis; Helicobacter Infections; Hypertension, Pulmonary; Kidney Diseases; Landau-Kleffner Syndrome; Macular Edema; Multiple Sclerosis; Retinoschisis; Sleep Apnea, Obstructive; Status Epilepticus; Stroke; Apnea; Carcinoma, Hepatocellular; Hydrocephalus, Normal Pressure; Pseudotumor Cerebri; Altitude Sickness; Edema; Epilepsy; Glaucoma; Glaucoma, Angle-Closure; Heart Failure; Seizures

Carbonic anhydrase II inhibitor


Small molecule Approved Unknown Unknown Digestive System Diseases Unknown


Small molecule Approved Unknown Unknown Lung Neoplasms; Polycystic Kidney Diseases; Rectal Neoplasms; Breast Neoplasms; Cardiovascular Diseases; Cerebral Hemorrhage; Heart Diseases; Heart Failure; Neoplasms; Pre-Eclampsia; Stroke; Vascular Diseases; Atherosclerosis; Coronary Disease; Diabetes Mellitus, Type 2; Hypercholesterolemia; Ovarian Neoplasms; Uterine Cervical Neoplasms; Hypertension Unknown

Small molecule

Approved

Unknown

Lung Neoplasms; Polycystic Kidney Diseases; Rectal Neoplasms; Breast Neoplasms; Cardiovascular Diseases; Cerebral Hemorrhage; Heart Diseases; Heart Failure; Neoplasms; Pre-Eclampsia; Stroke; Vascular Diseases; Atherosclerosis; Coronary Disease; Diabetes Mellitus, Type 2; Hypercholesterolemia; Ovarian Neoplasms; Uterine Cervical Neoplasms; Hypertension

Unknown


Small molecule Approved OTHER ORAL Burkitt Lymphoma; Astrocytoma; Blastic Plasmacytoid Dendritic Cell Neoplasm; Brain Neoplasms; Colitis; Glioblastoma; Glioma; Oligodendroglioma; Colitis, Ulcerative; Crohn Disease; Histiocytosis, Langerhans-Cell; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Lymphoid; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma Amidophosphoribosyltransferase inhibitor

Small molecule

Approved

OTHER

ORAL

Burkitt Lymphoma; Astrocytoma; Blastic Plasmacytoid Dendritic Cell Neoplasm; Brain Neoplasms; Colitis; Glioblastoma; Glioma; Oligodendroglioma; Colitis, Ulcerative; Crohn Disease; Histiocytosis, Langerhans-Cell; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Lymphoid; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma

Amidophosphoribosyltransferase inhibitor


Small molecule Approved OTHER INJECTION; SUBCUTANEOUS Muscular Dystrophy, Facioscapulohumeral; HIV Wasting Syndrome; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Weight Loss; Hypogonadism; Neoplasms; Orchitis Androgen Receptor agonist


Small molecule Approved Unknown Unknown Hernias, Diaphragmatic, Congenital; Paraganglioma; Pheochromocytoma; Cardiovascular Diseases Unknown


Small molecule Approved OTHER INJECTION; ORAL Urinary Bladder, Overactive; Peptic Ulcer Muscarinic acetylcholine receptor M1 antagonist


Small molecule Approved OTHER INTRALYMPHATIC; INTRAUTERINE Osteoarthritis, Knee; Carcinoma, Hepatocellular; Liver Neoplasms; Thrombosis; Neoplasms Diagnostic agent


Small molecule Approved Unknown Unknown Digestive System Diseases Unknown


Small molecule Approved Unknown Unknown Hypersensitivity Unknown


Small molecule Approved Unknown Unknown Cocaine-Related Disorders; Sciatica; Temporomandibular Joint Disorders; Parkinson Disease Unknown


Small molecule Approved CANCER; OTHER INJECTION; ORAL; TOPICAL Hematologic Neoplasms; Arthritis, Rheumatoid; Bronchiolitis Obliterans Syndrome; Crohn Disease; Epidermolysis Bullosa Acquisita; Pancreatic Neoplasms; Scleroderma, Diffuse; Sezary Syndrome; Graft vs Host Disease; Lymphoma; Mycosis Fungoides; Lymphoma, T-Cell; Psoriasis DNA inhibitor


Small molecule Approved Unknown Unknown Cardiovascular Diseases; Heart Diseases; Hypertension Adrenergic receptor alpha antagonist


Small molecule Approved Unknown Unknown Osteomyelitis; Hemorrhoids Unknown


Small molecule Approved OTHER INJECTION; ORAL Acquired Immunodeficiency Syndrome; Anemia; Blast Crisis; Brain Neoplasms; Chordoma; Genetic Diseases, Inborn; HIV Infections; Leukemia, Myeloid; Liver Neoplasms; Melanoma; Neoplasms, Germ Cell and Embryonal; Osteogenesis Imperfecta; Ovarian Neoplasms; Retinoblastoma; Wiskott-Aldrich Syndrome; X-Linked Combined Immunodeficiency Diseases; Adrenoleukodystrophy; Anemia, Sickle Cell; beta-Thalassemia; Breast Neoplasms, Male; Central Nervous System Neoplasms; Epidermolysis Bullosa; Fanconi Anemia; Fucosidosis; Gangliosidosis, GM1; Gaucher Disease; Glioma; Granulomatous Disease, Chronic; Hematologic Diseases; Hematologic Neoplasms; Hemoglobinopathies; Histiocytosis, Langerhans-Cell; Hodgkin Disease; Immune System Diseases; Immunologic Deficiency Syndromes; Inflammatory Breast Neoplasms; Kidney Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelomonocytic, Juvenile; Leukemia, Plasma Cell; Leukodystrophy, Globoid Cell; Leukodystrophy, Metachromatic; Lymphoma, AIDS-Related; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Myelodysplastic-Myeloproliferative Diseases; Myeloproliferative Disorders; Neoplasms, Plasma Cell; Neuronal Ceroid-Lipofuscinoses; Niemann-Pick Diseases; Osteopetrosis; Plasmacytoma; Primary Myelofibrosis; Sandhoff Disease; Severe Combined Immunodeficiency; Signs and Symptoms; Tay-Sachs Disease; Thalassemia; Wolman Disease; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Breast Neoplasms; Ganglioneuroblastoma; Graft vs Host Disease; Leukemia, Basophilic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Lymphoma; Multiple Myeloma; Myelodysplastic Syndromes; Neuroblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma; Sarcoma, Ewing; Thrombocythemia, Essential; Thrombosis; Hematopoietic Stem Cell Transplantation; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Neoplasms DNA inhibitor

Small molecule

Approved

OTHER

INJECTION; ORAL

Acquired Immunodeficiency Syndrome; Anemia; Blast Crisis; Brain Neoplasms; Chordoma; Genetic Diseases, Inborn; HIV Infections; Leukemia, Myeloid; Liver Neoplasms; Melanoma; Neoplasms, Germ Cell and Embryonal; Osteogenesis Imperfecta; Ovarian Neoplasms; Retinoblastoma; Wiskott-Aldrich Syndrome; X-Linked Combined Immunodeficiency Diseases; Adrenoleukodystrophy; Anemia, Sickle Cell; beta-Thalassemia; Breast Neoplasms, Male; Central Nervous System Neoplasms; Epidermolysis Bullosa; Fanconi Anemia; Fucosidosis; Gangliosidosis, GM1; Gaucher Disease; Glioma; Granulomatous Disease, Chronic; Hematologic Diseases; Hematologic Neoplasms; Hemoglobinopathies; Histiocytosis, Langerhans-Cell; Hodgkin Disease; Immune System Diseases; Immunologic Deficiency Syndromes; Inflammatory Breast Neoplasms; Kidney Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelomonocytic, Juvenile; Leukemia, Plasma Cell; Leukodystrophy, Globoid Cell; Leukodystrophy, Metachromatic; Lymphoma, AIDS-Related; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Myelodysplastic-Myeloproliferative Diseases; Myeloproliferative Disorders; Neoplasms, Plasma Cell; Neuronal Ceroid-Lipofuscinoses; Niemann-Pick Diseases; Osteopetrosis; Plasmacytoma; Primary Myelofibrosis; Sandhoff Disease; Severe Combined Immunodeficiency; Signs and Symptoms; Tay-Sachs Disease; Thalassemia; Wolman Disease; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Breast Neoplasms; Ganglioneuroblastoma; Graft vs Host Disease; Leukemia, Basophilic, Acute; Leukemia, Erythroblastic, Acute; Leukemia, Megakaryoblastic, Acute; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukemia, Myelomonocytic, Chronic; Lymphoma; Multiple Myeloma; Myelodysplastic Syndromes; Neuroblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma; Sarcoma, Ewing; Thrombocythemia, Essential; Thrombosis; Hematopoietic Stem Cell Transplantation; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Neoplasms

DNA inhibitor


Small molecule Approved Unknown Unknown Alzheimer Disease; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Depressive Disorder, Major; Dermatitis, Atopic; Diabetes Mellitus; Diabetes Mellitus, Type 2; Epilepsy; Essential Hypertension; Hematologic Neoplasms; Hypertriglyceridemia; Ischemic Stroke; Lymphoma; Melanoma; Nausea; Neoplasm Metastasis; Neoplasms; Non-alcoholic Fatty Liver Disease; Obesity; Osteoarthritis, Knee; Pancreatic Neoplasms; Parkinson Disease; Prostatic Neoplasms; Psoriasis; Thrombophlebitis; Urinary Bladder, Overactive; Hemorrhage; Hypertension, Pulmonary; Liver Cirrhosis; Polyendocrinopathies, Autoimmune; Aortic Valve Stenosis; Atherosclerosis; Atrial Fibrillation; Atrial Flutter; Brain Infarction; Cardiovascular Diseases; Cerebral Infarction; Coronary Disease; Heart Diseases; Heart Failure; Idiopathic Pulmonary Fibrosis; Ischemic Attack, Transient; Multiple Sclerosis, Relapsing-Remitting; Myocardial Infarction; Myocardial Ischemia; Peripheral Vascular Diseases; Pregnancy; Prostatic Neoplasms, Castration-Resistant; Pulmonary Embolism; Rheumatic Heart Disease; Stroke; Thrombocytopenia; Thromboembolism; Venous Thromboembolism; Venous Thrombosis; Thrombosis Unknown

Small molecule

Approved

Unknown

Alzheimer Disease; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Depressive Disorder, Major; Dermatitis, Atopic; Diabetes Mellitus; Diabetes Mellitus, Type 2; Epilepsy; Essential Hypertension; Hematologic Neoplasms; Hypertriglyceridemia; Ischemic Stroke; Lymphoma; Melanoma; Nausea; Neoplasm Metastasis; Neoplasms; Non-alcoholic Fatty Liver Disease; Obesity; Osteoarthritis, Knee; Pancreatic Neoplasms; Parkinson Disease; Prostatic Neoplasms; Psoriasis; Thrombophlebitis; Urinary Bladder, Overactive; Hemorrhage; Hypertension, Pulmonary; Liver Cirrhosis; Polyendocrinopathies, Autoimmune; Aortic Valve Stenosis; Atherosclerosis; Atrial Fibrillation; Atrial Flutter; Brain Infarction; Cardiovascular Diseases; Cerebral Infarction; Coronary Disease; Heart Diseases; Heart Failure; Idiopathic Pulmonary Fibrosis; Ischemic Attack, Transient; Multiple Sclerosis, Relapsing-Remitting; Myocardial Infarction; Myocardial Ischemia; Peripheral Vascular Diseases; Pregnancy; Prostatic Neoplasms, Castration-Resistant; Pulmonary Embolism; Rheumatic Heart Disease; Stroke; Thrombocytopenia; Thromboembolism; Venous Thromboembolism; Venous Thrombosis; Thrombosis

Unknown


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved OTHER ORAL Stroke; Epilepsy; Seizures GABA-A receptor; anion channel positive allosteric modulator


Small molecule Approved OTHER ORAL Unknown Nematode GABA-A receptor positive modulator


Small molecule Approved Unknown Unknown Hypotension; Pre-Eclampsia; Cardiovascular Diseases Unknown


Small molecule Approved Unknown ORAL Cocaine-Related Disorders; Cognition; Attention Deficit Disorder with Hyperactivity Dopamine transporter releasing agent


Small molecule Approved MUSCULOSKELETAL; OTHER ORAL Anemia, Diamond-Blackfan; Canavan Disease; Diabetes Mellitus, Type 2; Esophageal Stenosis; Fanconi Anemia; Frontotemporal Dementia; Gangliosidoses; Gaucher Disease; Glucose Intolerance; Hematologic Diseases; Lymphoma, Primary Effusion; Respiratory Syncytial Virus Infections; Status Asthmaticus; Acquired Immunodeficiency Syndrome; Adrenal Insufficiency; AIDS-Associated Nephropathy; Amyotrophic Lateral Sclerosis; Anemia, Hemolytic, Autoimmune; Autoimmune Diseases; Bell Palsy; Blast Crisis; Blastic Plasmacytoid Dendritic Cell Neoplasm; Burkitt Lymphoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Castleman Disease; Chemical and Drug Induced Liver Injury; Churg-Strauss Syndrome; Embolism, Cholesterol; Gastrointestinal Stromal Tumors; Geographic Atrophy; Glomerulosclerosis, Focal Segmental; Graves Ophthalmopathy; Hearing Loss; Hearing Loss, Sensorineural; Hemangioma; Hematologic Neoplasms; Hemophilia A; Hepatitis, Alcoholic; Hepatitis, Autoimmune; Hepatitis C; HIV Infections; Hypersensitivity; IgA Vasculitis; Immunoblastic Lymphadenopathy; Immunoglobulin G4-Related Disease; Kidney Neoplasms; Lichen Planus, Oral; Lung Diseases; Lung Neoplasms; Lymphohistiocytosis, Hemophagocytic; Lymphoma, AIDS-Related; Lymphoma, B-Cell; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell; Lymphoproliferative Disorders; Melanoma; Multiple Sclerosis, Relapsing-Remitting; Myelodysplastic Syndromes; Myeloproliferative Disorders; Nephritis, Interstitial; Neuromyelitis Optica; Opsoclonus-Myoclonus Syndrome; Pneumonia, Viral; Polycythemia Vera; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Premature Birth; Primary Myelofibrosis; Pulmonary Fibrosis; Stiff-Person Syndrome; Takayasu Arteritis; Thrombocythemia, Essential; Thymus Neoplasms; Vestibular Neuronitis; Alzheimer Disease; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Breast Neoplasms; Bronchiolitis Obliterans Syndrome; Cardiomyopathies; Central Nervous System Neoplasms; Cystic Fibrosis; Deafness; Giant Cell Arteritis; Glomerulonephritis, IGA; Glomerulonephritis, Membranous; Graft vs Host Disease; Granulomatosis with Polyangiitis; Heart Diseases; Heart Failure; Histiocytosis, Langerhans-Cell; Hodgkin Disease; Hypereosinophilic Syndrome; Idiopathic Pulmonary Fibrosis; Kidney Diseases; Kidney Failure, Chronic; Leukemia, Biphenotypic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid, Acute; Lupus Nephritis; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Microscopic Polyangiitis; Multiple Myeloma; Muscular Dystrophy, Duchenne; Myasthenia Gravis; Nasal Polyps; Neoplasms, Plasma Cell; Neuroblastoma; Pain; Pemphigoid, Bullous; Pericarditis; Polymyalgia Rheumatica; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Purpura, Thrombotic Thrombocytopenic; Renal Insufficiency, Chronic; Retroperitoneal Fibrosis; Rhinitis, Allergic, Perennial; Sarcoidosis, Pulmonary; Sarcoma; Sciatica; Severe Acute Respiratory Syndrome; Sinusitis; Tuberculosis; Urticaria; Uveitis; Uveitis, Intermediate; Vasculitis; Waldenstrom Macroglobulinemia; Addison Disease; Adrenal Hyperplasia, Congenital; Anemia; Anemia, Aplastic; Anemia, Hemolytic; Arthritis; Arthritis, Gouty; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Berylliosis; Brain Neoplasms; Bursitis; Chorioretinitis; Choroiditis; Colitis, Ulcerative; Conjunctivitis, Allergic; Crohn Disease; Dermatitis, Atopic; Dermatitis, Contact; Dermatitis, Exfoliative; Dermatitis Herpetiformis; Dermatitis, Seborrheic; Dermatomyositis; Endocrine System Diseases; Erythema Multiforme; Herpes Zoster Ophthalmicus; Hypercalcemia; Inflammation; Iridocyclitis; Iritis; Keratitis; Leukemia; Lupus Erythematosus, Systemic; Lymphoma; Multiple Sclerosis; Mycosis Fungoides; Myocarditis; Neoplasms; Nephrotic Syndrome; Ophthalmia, Sympathetic; Optic Neuritis; Osteoarthritis; Pemphigus; Peptic Ulcer; Pneumonia; Polymyositis; Psoriasis; Pulmonary Eosinophilia; Purpura, Thrombocytopenic, Idiopathic; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal; Sarcoidosis; Serum Sickness; Spondylitis; Spondylitis, Ankylosing; Stevens-Johnson Syndrome; Synovitis; Tennis Elbow; Tenosynovitis; Thrombocytopenia; Thyroiditis, Subacute; Trichinellosis; Tuberculosis, Meningeal; Tuberculosis, Pulmonary; Uveitis, Posterior Glucocorticoid receptor agonist

Small molecule

Approved

MUSCULOSKELETAL; OTHER

ORAL

Anemia, Diamond-Blackfan; Canavan Disease; Diabetes Mellitus, Type 2; Esophageal Stenosis; Fanconi Anemia; Frontotemporal Dementia; Gangliosidoses; Gaucher Disease; Glucose Intolerance; Hematologic Diseases; Lymphoma, Primary Effusion; Respiratory Syncytial Virus Infections; Status Asthmaticus; Acquired Immunodeficiency Syndrome; Adrenal Insufficiency; AIDS-Associated Nephropathy; Amyotrophic Lateral Sclerosis; Anemia, Hemolytic, Autoimmune; Autoimmune Diseases; Bell Palsy; Blast Crisis; Blastic Plasmacytoid Dendritic Cell Neoplasm; Burkitt Lymphoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Castleman Disease; Chemical and Drug Induced Liver Injury; Churg-Strauss Syndrome; Embolism, Cholesterol; Gastrointestinal Stromal Tumors; Geographic Atrophy; Glomerulosclerosis, Focal Segmental; Graves Ophthalmopathy; Hearing Loss; Hearing Loss, Sensorineural; Hemangioma; Hematologic Neoplasms; Hemophilia A; Hepatitis, Alcoholic; Hepatitis, Autoimmune; Hepatitis C; HIV Infections; Hypersensitivity; IgA Vasculitis; Immunoblastic Lymphadenopathy; Immunoglobulin G4-Related Disease; Kidney Neoplasms; Lichen Planus, Oral; Lung Diseases; Lung Neoplasms; Lymphohistiocytosis, Hemophagocytic; Lymphoma, AIDS-Related; Lymphoma, B-Cell; Lymphoma, Large-Cell, Anaplastic; Lymphoma, T-Cell; Lymphoproliferative Disorders; Melanoma; Multiple Sclerosis, Relapsing-Remitting; Myelodysplastic Syndromes; Myeloproliferative Disorders; Nephritis, Interstitial; Neuromyelitis Optica; Opsoclonus-Myoclonus Syndrome; Pneumonia, Viral; Polycythemia Vera; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Premature Birth; Primary Myelofibrosis; Pulmonary Fibrosis; Stiff-Person Syndrome; Takayasu Arteritis; Thrombocythemia, Essential; Thymus Neoplasms; Vestibular Neuronitis; Alzheimer Disease; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Breast Neoplasms; Bronchiolitis Obliterans Syndrome; Cardiomyopathies; Central Nervous System Neoplasms; Cystic Fibrosis; Deafness; Giant Cell Arteritis; Glomerulonephritis, IGA; Glomerulonephritis, Membranous; Graft vs Host Disease; Granulomatosis with Polyangiitis; Heart Diseases; Heart Failure; Histiocytosis, Langerhans-Cell; Hodgkin Disease; Hypereosinophilic Syndrome; Idiopathic Pulmonary Fibrosis; Kidney Diseases; Kidney Failure, Chronic; Leukemia, Biphenotypic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid, Acute; Lupus Nephritis; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Microscopic Polyangiitis; Multiple Myeloma; Muscular Dystrophy, Duchenne; Myasthenia Gravis; Nasal Polyps; Neoplasms, Plasma Cell; Neuroblastoma; Pain; Pemphigoid, Bullous; Pericarditis; Polymyalgia Rheumatica; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Pulmonary Disease, Chronic Obstructive; Purpura, Thrombotic Thrombocytopenic; Renal Insufficiency, Chronic; Retroperitoneal Fibrosis; Rhinitis, Allergic, Perennial; Sarcoidosis, Pulmonary; Sarcoma; Sciatica; Severe Acute Respiratory Syndrome; Sinusitis; Tuberculosis; Urticaria; Uveitis; Uveitis, Intermediate; Vasculitis; Waldenstrom Macroglobulinemia; Addison Disease; Adrenal Hyperplasia, Congenital; Anemia; Anemia, Aplastic; Anemia, Hemolytic; Arthritis; Arthritis, Gouty; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Berylliosis; Brain Neoplasms; Bursitis; Chorioretinitis; Choroiditis; Colitis, Ulcerative; Conjunctivitis, Allergic; Crohn Disease; Dermatitis, Atopic; Dermatitis, Contact; Dermatitis, Exfoliative; Dermatitis Herpetiformis; Dermatitis, Seborrheic; Dermatomyositis; Endocrine System Diseases; Erythema Multiforme; Herpes Zoster Ophthalmicus; Hypercalcemia; Inflammation; Iridocyclitis; Iritis; Keratitis; Leukemia; Lupus Erythematosus, Systemic; Lymphoma; Multiple Sclerosis; Mycosis Fungoides; Myocarditis; Neoplasms; Nephrotic Syndrome; Ophthalmia, Sympathetic; Optic Neuritis; Osteoarthritis; Pemphigus; Peptic Ulcer; Pneumonia; Polymyositis; Psoriasis; Pulmonary Eosinophilia; Purpura, Thrombocytopenic, Idiopathic; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal; Sarcoidosis; Serum Sickness; Spondylitis; Spondylitis, Ankylosing; Stevens-Johnson Syndrome; Synovitis; Tennis Elbow; Tenosynovitis; Thrombocytopenia; Thyroiditis, Subacute; Trichinellosis; Tuberculosis, Meningeal; Tuberculosis, Pulmonary; Uveitis, Posterior

Glucocorticoid receptor agonist


Small molecule Approved Unknown Unknown Unknown Dihydrofolate reductase inhibitor


Small molecule Approved OTHER ORAL; TRANSDERMAL Alcoholism; Hypotension, Orthostatic; Opioid-Related Disorders; Postoperative Complications; Amphetamine-Related Disorders; Brain Injuries; Chronic Pain; Cocaine-Related Disorders; Feeding and Eating Disorders; Parkinson Disease; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Stress Disorders, Post-Traumatic; Substance-Related Disorders; Alzheimer Disease; Anemia, Sickle Cell; Asthenia; Bipolar Disorder; Brain Neoplasms; Delirium; Dementia; Depressive Disorder; Depressive Disorder, Major; Fatigue; Hematologic Neoplasms; Multiple Sclerosis; Neoplasms; Tobacco Use Disorder; Attention Deficit Disorder with Hyperactivity; Narcolepsy Dopamine transporter inhibitor

Small molecule

Approved

OTHER

ORAL; TRANSDERMAL

Alcoholism; Hypotension, Orthostatic; Opioid-Related Disorders; Postoperative Complications; Amphetamine-Related Disorders; Brain Injuries; Chronic Pain; Cocaine-Related Disorders; Feeding and Eating Disorders; Parkinson Disease; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Stress Disorders, Post-Traumatic; Substance-Related Disorders; Alzheimer Disease; Anemia, Sickle Cell; Asthenia; Bipolar Disorder; Brain Neoplasms; Delirium; Dementia; Depressive Disorder; Depressive Disorder, Major; Fatigue; Hematologic Neoplasms; Multiple Sclerosis; Neoplasms; Tobacco Use Disorder; Attention Deficit Disorder with Hyperactivity; Narcolepsy

Dopamine transporter inhibitor


Small molecule Approved Unknown Unknown Diabetes Mellitus; Fibromyalgia; HIV Infections; Hypotension, Orthostatic; Muscular Atrophy, Spinal; Myasthenia Gravis Unknown


Small molecule Approved Unknown Unknown Pregnancy; Cataract; Pain Unknown


Small molecule Approved Unknown Unknown Parkinson Disease Unknown


Protein Approved Unknown Unknown Unknown Melanocortin receptor 2 agonist

Small molecule

Approved

Unknown

Adenocarcinoma; Carcinoma, Renal Cell; Central Nervous System Neoplasms; Colitis, Ulcerative; Cystic Fibrosis; Glioma; Hepatitis C; Hepatitis C, Chronic; Hidradenitis Suppurativa; Insulin Resistance; Leukemia, Myeloid, Acute; Lung Diseases, Interstitial; Lymphangioleiomyomatosis; Melanoma; Multiple Myeloma; Myelodysplastic Syndromes; Neoplasms, Plasma Cell; Osteosarcoma; Ovarian Neoplasms; Prostatic Neoplasms; Retinitis Pigmentosa; Biliary Tract Neoplasms; Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Cholangiocarcinoma; Colorectal Neoplasms; Communicable Diseases; Crohn Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glioblastoma; Glomerulonephritis, IGA; Hearing Loss; HIV Infections; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Lichen Planus; Lung Neoplasms; Mastocytosis; Multiple Sclerosis, Chronic Progressive; Neoplasms; Osteoarthritis, Knee; Pancreatic Neoplasms; Porphyria Cutanea Tarda; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Small Cell Lung Carcinoma; Virus Diseases; Zellweger Syndrome; Abortion, Habitual; Antiphospholipid Syndrome; Arthritis, Rheumatoid; Coronavirus Infections; Giant Cell Arteritis; Graft vs Host Disease; Infections; Influenza, Human; Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic; Osteoarthritis; Pericarditis; Pneumonia; Pneumonia, Pneumocystis; Pneumonia, Viral; Polyendocrinopathies, Autoimmune; Pre-Eclampsia; Pregnancy; Respiratory Distress Syndrome; Respiratory Insufficiency; Sarcoidosis, Pulmonary; Severe Acute Respiratory Syndrome; Sjogren's Syndrome; Thrombocytopenia; Malaria

Unknown


Small molecule Approved Unknown Unknown Burkitt Lymphoma; Leukemia; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Shock, Septic; Asthma Glucocorticoid receptor agonist


Small molecule Approved Unknown Unknown Bipolar Disorder; Amphetamine-Related Disorders; Cocaine-Related Disorders; Multiple Sclerosis; Opioid-Related Disorders; Schizophrenia; Stress Disorders, Post-Traumatic; Stroke; Paraganglioma; Arteriosclerosis; Attention Deficit Disorder with Hyperactivity; Narcolepsy; Substance-Related Disorders Dopamine transporter releasing agent


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved OTHER ORAL Altitude Sickness Dopamine D2 receptor antagonist


Small molecule Approved OTHER ORAL Unknown Muscarinic acetylcholine receptor M1 antagonist


Small molecule Approved Unknown Unknown Hypotension, Orthostatic; Lipoma; Orthostatic Intolerance; Atrial Fibrillation; Kidney Calculi; Cardiovascular Diseases; Lung Diseases, Obstructive Unknown