DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 10647


Antibody Approved IMMUNE SYSTEM; OTHER INJECTION Diabetes Mellitus, Type 1; Carcinoma, Renal Cell; Paraproteinemias; Schizophrenia; Kidney Neoplasms; Myelodysplastic Syndromes; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Multiple Myeloma; Severe Acute Respiratory Syndrome; Castleman Disease; Immune System Diseases Interleukin-6 inhibitor


Small molecule Approved CANCER; HEMATOLOGY; OTHER ORAL Carcinoma, Pancreatic Ductal; Leukemia, Myeloid, Acute; Multiple Myeloma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Myelofibrosis; Rhinitis, Allergic, Seasonal; Amyloidosis; Hodgkin Disease; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Waldenstrom Macroglobulinemia; Lymphoma; Lymphoma, Follicular; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Neoplasms PI3-kinase p110-delta subunit inhibitor

Small molecule

Approved

CANCER; HEMATOLOGY; OTHER

ORAL

Carcinoma, Pancreatic Ductal; Leukemia, Myeloid, Acute; Multiple Myeloma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Myelofibrosis; Rhinitis, Allergic, Seasonal; Amyloidosis; Hodgkin Disease; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Waldenstrom Macroglobulinemia; Lymphoma; Lymphoma, Follicular; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Neoplasms

PI3-kinase p110-delta subunit inhibitor


Antibody Approved GASTROINTESTINAL INJECTION HIV Infections; Inflammatory Bowel Diseases; Melanoma; Celiac Disease; Colitis; Infections; Colitis, Ulcerative; Crohn Disease; Immune System Diseases Integrin alpha-4/beta-7 inhibitor


Small molecule Approved Unknown Unknown Hematologic Neoplasms; Gaucher Disease Unknown


Small molecule Approved HEMATOLOGY INTRAVENOUS Adenocarcinoma; Blast Crisis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Hematologic Neoplasms; Hodgkin Disease; Lymphoma; Lymphoma, Follicular; Mycosis Fungoides; Sarcoma; Small Cell Lung Carcinoma; Burkitt Lymphoma; Carcinoma; Carcinoma, Endometrioid; Cystadenoma, Serous; Fallopian Tube Neoplasms; Glioblastoma; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid, Acute; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous; Mesothelioma; Multiple Myeloma; Myelodysplastic Syndromes; Peritoneal Neoplasms; Thymoma; Lymphoma, T-Cell; Lymphoma, T-Cell, Peripheral; Neoplasms Histone deacetylase inhibitor

Small molecule

Approved

HEMATOLOGY

INTRAVENOUS

Adenocarcinoma; Blast Crisis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Hematologic Neoplasms; Hodgkin Disease; Lymphoma; Lymphoma, Follicular; Mycosis Fungoides; Sarcoma; Small Cell Lung Carcinoma; Burkitt Lymphoma; Carcinoma; Carcinoma, Endometrioid; Cystadenoma, Serous; Fallopian Tube Neoplasms; Glioblastoma; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid, Acute; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous; Mesothelioma; Multiple Myeloma; Myelodysplastic Syndromes; Peritoneal Neoplasms; Thymoma; Lymphoma, T-Cell; Lymphoma, T-Cell, Peripheral; Neoplasms

Histone deacetylase inhibitor


Small molecule Approved OTHER ORAL Central Nervous System Neoplasms; Glioma; Head and Neck Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Hypertension, Pulmonary; Inflammatory Breast Neoplasms; Lymphoma; Neoplasm Metastasis; Neuroendocrine Tumors; Rhabdomyosarcoma; Uterine Neoplasms; Bile Duct Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Cholangiocarcinoma; Colorectal Neoplasms; Glioblastoma; Hemangiosarcoma; Lung Neoplasms; Melanoma; Mesothelioma; Neoplasms, Germ Cell and Embryonal; Osteosarcoma; Pancreatic Neoplasms; Sarcoma; Sarcoma, Ewing; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Non-Small-Cell Lung; Endometrial Neoplasms; Fallopian Tube Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Stomach Neoplasms; Neoplasms; Ovarian Neoplasms PARP 1, 2 and 3 inhibitor

Small molecule

Approved

OTHER

ORAL

Central Nervous System Neoplasms; Glioma; Head and Neck Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Hypertension, Pulmonary; Inflammatory Breast Neoplasms; Lymphoma; Neoplasm Metastasis; Neuroendocrine Tumors; Rhabdomyosarcoma; Uterine Neoplasms; Bile Duct Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Cholangiocarcinoma; Colorectal Neoplasms; Glioblastoma; Hemangiosarcoma; Lung Neoplasms; Melanoma; Mesothelioma; Neoplasms, Germ Cell and Embryonal; Osteosarcoma; Pancreatic Neoplasms; Sarcoma; Sarcoma, Ewing; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Non-Small-Cell Lung; Endometrial Neoplasms; Fallopian Tube Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Stomach Neoplasms; Neoplasms; Ovarian Neoplasms

PARP 1, 2 and 3 inhibitor


Small molecule Approved DERMATOLOGY; IMMUNE SYSTEM; OTHER; RHEUMATOLOGY ORAL; UNKNOWN Stomatitis, Aphthous; Lupus Erythematosus, Discoid; Uveitis; Acne Vulgaris; Alcoholism; Arthritis, Rheumatoid; Colitis, Ulcerative; Dermatitis; Dermatitis, Allergic Contact; Dermatitis, Atopic; Dermatomyositis; Eczema; Gout; Hidradenitis Suppurativa; Lichen Planus; Lichen Planus, Oral; Prostatitis; Rosacea; Vitiligo; Behcet Syndrome; Severe Acute Respiratory Syndrome; Spondylitis, Ankylosing; Arthritis, Psoriatic; Immune System Diseases; Oral Ulcer; Psoriasis Phosphodiesterase 4 inhibitor

Small molecule

Approved

DERMATOLOGY; IMMUNE SYSTEM; OTHER; RHEUMATOLOGY

ORAL; UNKNOWN

Stomatitis, Aphthous; Lupus Erythematosus, Discoid; Uveitis; Acne Vulgaris; Alcoholism; Arthritis, Rheumatoid; Colitis, Ulcerative; Dermatitis; Dermatitis, Allergic Contact; Dermatitis, Atopic; Dermatomyositis; Eczema; Gout; Hidradenitis Suppurativa; Lichen Planus; Lichen Planus, Oral; Prostatitis; Rosacea; Vitiligo; Behcet Syndrome; Severe Acute Respiratory Syndrome; Spondylitis, Ankylosing; Arthritis, Psoriatic; Immune System Diseases; Oral Ulcer; Psoriasis

Phosphodiesterase 4 inhibitor


Small molecule Unknown Unknown Unknown Idiopathic Pulmonary Fibrosis; Scleroderma, Systemic Fibroblast growth factor receptor inhibitor


Antibody Approved CANCER INJECTION Multiple Myeloma; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Hematologic Neoplasms; Leukemia, Biphenotypic, Acute; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Neoplasms; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma B-lymphocyte antigen CD19 cross-linking agent


Small molecule Approved DERMATOLOGY TOPICAL Onychomycosis Lanosterol 14-alpha demethylase inhibitor


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Sleep Apnea Syndromes; Tobacco Use Disorder; Alcoholism; Alzheimer Disease; Opioid-Related Disorders; Restless Legs Syndrome; Sleep Wake Disorders; Smoking Cessation; Delirium; Sleep Initiation and Maintenance Disorders Orexin receptor antagonist


Small molecule Approved Unknown Unknown Communicable Diseases; Urinary Tract Infections; Infections; Pneumonia; Pneumonia, Ventilator-Associated; Pyelonephritis Unknown


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Glycogen Storage Disease Type I; Hyponatremia; Inappropriate ADH Syndrome; Kidney Calculi; Kidney Diseases; Non-alcoholic Fatty Liver Disease; Polycystic Ovary Syndrome; Prediabetic State; Diabetes, Gestational; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Heart Failure; Insulin Resistance; Myocardial Infarction; Renal Insufficiency, Chronic; Diabetes Mellitus; Diabetes Mellitus, Type 2 Sodium/glucose cotransporter 2 inhibitor

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER

ORAL

Glycogen Storage Disease Type I; Hyponatremia; Inappropriate ADH Syndrome; Kidney Calculi; Kidney Diseases; Non-alcoholic Fatty Liver Disease; Polycystic Ovary Syndrome; Prediabetic State; Diabetes, Gestational; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Heart Failure; Insulin Resistance; Myocardial Infarction; Renal Insufficiency, Chronic; Diabetes Mellitus; Diabetes Mellitus, Type 2

Sodium/glucose cotransporter 2 inhibitor


Small molecule Approved Unknown Unknown Intraabdominal Infections; Urinary Tract Infections Bacterial penicillin-binding protein inhibitor


Protein Approved DIABETES DRUGS & ENDOCRINOLOGY INJECTION Diabetes Mellitus, Type 1; Heart Failure; Diabetes Mellitus; Diabetes Mellitus, Type 2 Glucagon-like peptide 1 receptor agonist


Small molecule Approved Unknown Unknown Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Heart Failure Sodium/glucose cotransporter 2 inhibitor


Small molecule Approved OTHER INTRAVENOUS Influenza, Human; Influenza, Human; Virus Diseases Neuraminidase inhibitor


Antibody Approved DERMATOLOGY UNKNOWN Carcinoma, Intraductal, Noninfiltrating; Smoldering Multiple Myeloma; Carcinoma, Basal Cell; Glioma; HIV Infections; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Lymphoid; Liver Neoplasms; Lymphoma, Mantle-Cell; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Neuroblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Uterine Neoplasms; Adrenal Cortex Neoplasms; Anus Neoplasms; Biliary Tract Neoplasms; Brain Neoplasms; Breast Neoplasms, Male; Carcinoid Tumor; Carcinoma, Adenoid Cystic; Carcinoma in Situ; Carcinoma, Medullary; Carcinoma, Neuroendocrine; Carcinoma, Pancreatic Ductal; Cholangiocarcinoma; Colonic Neoplasms; Gallbladder Neoplasms; Gastrointestinal Stromal Tumors; Genital Neoplasms, Female; Gestational Trophoblastic Disease; Glioblastoma; Gliosarcoma; Granuloma, Lethal Midline; Hemangiosarcoma; Hematologic Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Inflammatory Breast Neoplasms; Kidney Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Leukoplakia; Leukoplakia, Oral; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Meningeal Carcinomatosis; Meningeal Neoplasms; Meningioma; Mouth Neoplasms; Mycosis Fungoides; Myelodysplastic Syndromes; Neoplasm Metastasis; Neurilemmoma; Neuroendocrine Tumors; Oropharyngeal Neoplasms; Osteosarcoma; Pancreatic Neoplasms; Papilloma; Parotid Neoplasms; Penile Neoplasms; Pneumonia, Viral; Rectal Neoplasms; Salivary Gland Neoplasms; Sarcoma; Sarcoma, Alveolar Soft Part; Sarcoma, Kaposi; Scleroderma, Systemic; Severe Acute Respiratory Syndrome; Sezary Syndrome; Skin Neoplasms; Squamous Cell Carcinoma of Head and Neck; Thymoma; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Triple Negative Breast Neoplasms; Vulvar Neoplasms; Waldenstrom Macroglobulinemia; Adenocarcinoma of Lung; Breast Carcinoma In Situ; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Merkel Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Colorectal Neoplasms; Endometrial Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Head and Neck Neoplasms; Hodgkin Disease; Lung Neoplasms; Mesothelioma; Multiple Myeloma; Nasopharyngeal Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Stomach Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Melanoma; Neoplasms Programmed cell death protein 1 inhibitor

Antibody

Approved

DERMATOLOGY

UNKNOWN

Carcinoma, Intraductal, Noninfiltrating; Smoldering Multiple Myeloma; Carcinoma, Basal Cell; Glioma; HIV Infections; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Lymphoid; Liver Neoplasms; Lymphoma, Mantle-Cell; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Neuroblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Uterine Neoplasms; Adrenal Cortex Neoplasms; Anus Neoplasms; Biliary Tract Neoplasms; Brain Neoplasms; Breast Neoplasms, Male; Carcinoid Tumor; Carcinoma, Adenoid Cystic; Carcinoma in Situ; Carcinoma, Medullary; Carcinoma, Neuroendocrine; Carcinoma, Pancreatic Ductal; Cholangiocarcinoma; Colonic Neoplasms; Gallbladder Neoplasms; Gastrointestinal Stromal Tumors; Genital Neoplasms, Female; Gestational Trophoblastic Disease; Glioblastoma; Gliosarcoma; Granuloma, Lethal Midline; Hemangiosarcoma; Hematologic Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Inflammatory Breast Neoplasms; Kidney Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Leukoplakia; Leukoplakia, Oral; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Meningeal Carcinomatosis; Meningeal Neoplasms; Meningioma; Mouth Neoplasms; Mycosis Fungoides; Myelodysplastic Syndromes; Neoplasm Metastasis; Neurilemmoma; Neuroendocrine Tumors; Oropharyngeal Neoplasms; Osteosarcoma; Pancreatic Neoplasms; Papilloma; Parotid Neoplasms; Penile Neoplasms; Pneumonia, Viral; Rectal Neoplasms; Salivary Gland Neoplasms; Sarcoma; Sarcoma, Alveolar Soft Part; Sarcoma, Kaposi; Scleroderma, Systemic; Severe Acute Respiratory Syndrome; Sezary Syndrome; Skin Neoplasms; Squamous Cell Carcinoma of Head and Neck; Thymoma; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Triple Negative Breast Neoplasms; Vulvar Neoplasms; Waldenstrom Macroglobulinemia; Adenocarcinoma of Lung; Breast Carcinoma In Situ; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Merkel Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Colorectal Neoplasms; Endometrial Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Head and Neck Neoplasms; Hodgkin Disease; Lung Neoplasms; Mesothelioma; Multiple Myeloma; Nasopharyngeal Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Stomach Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Melanoma; Neoplasms

Programmed cell death protein 1 inhibitor


Protein Approved NEUROLOGY DRUGS & NERVOUS SYSTEM INJECTION Renal Insufficiency; Multiple Sclerosis, Relapsing-Remitting; Severe Acute Respiratory Syndrome; Multiple Sclerosis Interferon alpha/beta receptor agonist


Small molecule Approved Unknown Unknown Carcinoma, Non-Small-Cell Lung; Opioid-Related Disorders; Ileus; Constipation Unknown


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Acute Kidney Injury; Atrial Fibrillation; Aging; Alzheimer Disease; Pancreatic Neoplasms; Prostatic Neoplasms; Breast Neoplasms; Cystinuria; Diabetic Nephropathies; Heart Failure, Diastolic; Hyperuricemia; Metabolic Syndrome; Obesity; Weight Loss; Coronary Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Heart Failure; Non-alcoholic Fatty Liver Disease; Polycystic Ovary Syndrome; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; Diabetes Mellitus Sodium/glucose cotransporter 2 inhibitor

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER

ORAL

Acute Kidney Injury; Atrial Fibrillation; Aging; Alzheimer Disease; Pancreatic Neoplasms; Prostatic Neoplasms; Breast Neoplasms; Cystinuria; Diabetic Nephropathies; Heart Failure, Diastolic; Hyperuricemia; Metabolic Syndrome; Obesity; Weight Loss; Coronary Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Heart Failure; Non-alcoholic Fatty Liver Disease; Polycystic Ovary Syndrome; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; Diabetes Mellitus

Sodium/glucose cotransporter 2 inhibitor


Small molecule Approved Unknown Unknown Liver Diseases; Asthma; Pulmonary Disease, Chronic Obstructive; Lung Diseases, Obstructive Unknown


Small molecule Approved Unknown Unknown Esophageal Neoplasms; Graft vs Host Disease; Liver Diseases; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Carcinoma, Basal Cell; Leukemia; Medulloblastoma; Multiple Myeloma; Neoplasms Unknown


Small molecule Unknown Unknown Unknown Carcinoma, Non-Small-Cell Lung Epidermal growth factor receptor erbB1 inhibitor


Antibody Approved RESPIRATORY INJECTION Diffuse Intrinsic Pontine Glioma; Genital Neoplasms, Female; Hepatitis D; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma, Mantle-Cell; Lymphoma, T-Cell; Mycosis Fungoides; Neoplasm Metastasis; Nerve Sheath Neoplasms; Neuroblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retroperitoneal Neoplasms; Sepsis; Sezary Syndrome; Triple Negative Breast Neoplasms; Adenocarcinoma; Adrenal Cortex Neoplasms; Basal Cell Nevus Syndrome; Biliary Tract Neoplasms; Carcinoid Tumor; Carcinoma; Carcinoma, Basal Cell; Carcinoma, Large Cell; Carcinoma, Merkel Cell; Carcinoma, Neuroendocrine; Carcinoma, Pancreatic Ductal; Carcinoma, Small Cell; Cholangiocarcinoma; Chordoma; Colonic Neoplasms; Colorectal Neoplasms; Endometrial Neoplasms; Fallopian Tube Neoplasms; Gastrointestinal Stromal Tumors; Glioma; Gliosarcoma; Hemangiosarcoma; Hematologic Neoplasms; Hepatitis B, Chronic; Histiocytoma, Malignant Fibrous; Inflammatory Breast Neoplasms; Leiomyosarcoma; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Leukoplakia, Oral; Liposarcoma; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Meningioma; Myelodysplastic Syndromes; Nasopharyngeal Neoplasms; Neoplasms, Germ Cell and Embryonal; Oligodendroglioma; Oropharyngeal Neoplasms; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Pituitary Neoplasms; Pneumonia, Viral; Prostatic Neoplasms; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Retroviridae Infections; Salivary Gland Neoplasms; Sarcoma, Kaposi; Severe Acute Respiratory Syndrome; Small Cell Lung Carcinoma; Squamous Cell Carcinoma of Head and Neck; Thyroid Neoplasms; Uterine Cervical Neoplasms; Adenocarcinoma of Lung; Brain Neoplasms; Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Esophageal Neoplasms; Glioblastoma; Head and Neck Neoplasms; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Lymphoma, Follicular; Mesothelioma; Multiple Myeloma; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Skin Neoplasms; Stomach Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Hodgkin Disease; Melanoma; Neoplasms Programmed cell death protein 1 inhibitor

Antibody

Approved

RESPIRATORY

INJECTION

Diffuse Intrinsic Pontine Glioma; Genital Neoplasms, Female; Hepatitis D; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma, Mantle-Cell; Lymphoma, T-Cell; Mycosis Fungoides; Neoplasm Metastasis; Nerve Sheath Neoplasms; Neuroblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retroperitoneal Neoplasms; Sepsis; Sezary Syndrome; Triple Negative Breast Neoplasms; Adenocarcinoma; Adrenal Cortex Neoplasms; Basal Cell Nevus Syndrome; Biliary Tract Neoplasms; Carcinoid Tumor; Carcinoma; Carcinoma, Basal Cell; Carcinoma, Large Cell; Carcinoma, Merkel Cell; Carcinoma, Neuroendocrine; Carcinoma, Pancreatic Ductal; Carcinoma, Small Cell; Cholangiocarcinoma; Chordoma; Colonic Neoplasms; Colorectal Neoplasms; Endometrial Neoplasms; Fallopian Tube Neoplasms; Gastrointestinal Stromal Tumors; Glioma; Gliosarcoma; Hemangiosarcoma; Hematologic Neoplasms; Hepatitis B, Chronic; Histiocytoma, Malignant Fibrous; Inflammatory Breast Neoplasms; Leiomyosarcoma; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Leukoplakia, Oral; Liposarcoma; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Meningioma; Myelodysplastic Syndromes; Nasopharyngeal Neoplasms; Neoplasms, Germ Cell and Embryonal; Oligodendroglioma; Oropharyngeal Neoplasms; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Pituitary Neoplasms; Pneumonia, Viral; Prostatic Neoplasms; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Retroviridae Infections; Salivary Gland Neoplasms; Sarcoma, Kaposi; Severe Acute Respiratory Syndrome; Small Cell Lung Carcinoma; Squamous Cell Carcinoma of Head and Neck; Thyroid Neoplasms; Uterine Cervical Neoplasms; Adenocarcinoma of Lung; Brain Neoplasms; Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Esophageal Neoplasms; Glioblastoma; Head and Neck Neoplasms; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Lymphoma, Follicular; Mesothelioma; Multiple Myeloma; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Skin Neoplasms; Stomach Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Hodgkin Disease; Melanoma; Neoplasms

Programmed cell death protein 1 inhibitor


Small molecule Approved Unknown Unknown Severe Acute Respiratory Syndrome; Cardiomyopathy, Hypertrophic; Hypertension; Peripheral Arterial Disease; Chagas Cardiomyopathy; Hypertension, Pulmonary; Myocardial Infarction; ST Elevation Myocardial Infarction; Heart Failure Neprilysin inhibitor


Small molecule Unknown Unknown Unknown Rectal Neoplasms; Colorectal Neoplasms Thymidine phosphorylase inhibitor


Small molecule Approved Unknown ORAL Cholestasis; Obesity; Smith-Lemli-Opitz Syndrome; Barrett Esophagus; Diarrhea; Fatty Liver; Lipodystrophy, Familial Partial; Liver Cirrhosis, Biliary; Non-alcoholic Fatty Liver Disease; Liver Diseases; Peroxisomal Disorders Unknown


Small molecule Approved Unknown Unknown Hyperkalemia Potassium chelating agent


Small molecule Approved Unknown Unknown Postoperative Nausea and Vomiting; Nausea Unknown


Small molecule Approved Unknown INHALATION Status Asthmaticus; Pulmonary Disease, Chronic Obstructive Unknown


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved Unknown ORAL Alcoholism; Borderline Personality Disorder; Alzheimer Disease; Bipolar Disorder; Depressive Disorder; Psychomotor Agitation; Sleep Wake Disorders; Stress Disorders, Post-Traumatic; Depressive Disorder, Major; Psychotic Disorders; Schizophrenia Dopamine D2 receptor partial agonist


Small molecule Approved Unknown Unknown Breast Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms Unknown

Small molecule

Approved

Unknown

INTRAVENOUS

Leukemia, Lymphocytic, Chronic, B-Cell; Sarcoma, Ewing; Breast Neoplasms; Chondrosarcoma, Mesenchymal; Endocrine Gland Neoplasms; Fallopian Tube Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Liposarcoma, Myxoid; Meningioma; Mesothelioma; Pancreatic Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Soft Tissue Neoplasms; Ovarian Neoplasms; Sarcoma; Leiomyosarcoma; Liposarcoma; Neoplasms

DNA inhibitor