DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 10647


Small molecule Approved CANCER; HEMATOLOGY; OTHER ORAL Carcinoma, Pancreatic Ductal; Leukemia, Myeloid, Acute; Multiple Myeloma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Myelofibrosis; Rhinitis, Allergic, Seasonal; Amyloidosis; Hodgkin Disease; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Waldenstrom Macroglobulinemia; Lymphoma; Lymphoma, Follicular; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Neoplasms PI3-kinase p110-delta subunit inhibitor

Small molecule

Approved

CANCER; HEMATOLOGY; OTHER

ORAL

Carcinoma, Pancreatic Ductal; Leukemia, Myeloid, Acute; Multiple Myeloma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Myelofibrosis; Rhinitis, Allergic, Seasonal; Amyloidosis; Hodgkin Disease; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Waldenstrom Macroglobulinemia; Lymphoma; Lymphoma, Follicular; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Neoplasms

PI3-kinase p110-delta subunit inhibitor


Antibody Approved GASTROINTESTINAL INJECTION Diabetes Mellitus, Type 1; Inflammatory Bowel Diseases; Melanoma; Celiac Disease; Colitis; HIV Infections; Infections; Neoplasms; Salivary Gland Neoplasms; Pouchitis; Colitis, Ulcerative; Crohn Disease Integrin alpha-4/beta-7 inhibitor


Small molecule Approved DERMATOLOGY TOPICAL Onychomycosis Lanosterol 14-alpha demethylase inhibitor


Small molecule Approved DERMATOLOGY; IMMUNE SYSTEM; OTHER; RHEUMATOLOGY ORAL; UNKNOWN Lupus Erythematosus, Discoid; Uveitis; Acne Vulgaris; Alcoholism; Arthritis, Rheumatoid; Colitis, Ulcerative; Dermatitis; Dermatitis, Allergic Contact; Dermatitis, Atopic; Dermatomyositis; Eczema; Erythema Multiforme; Gout; Hidradenitis Suppurativa; Lichen Planus; Lichen Planus, Oral; Prostatitis; Rosacea; Vitiligo; Influenza, Human; Pneumonia; Severe Acute Respiratory Syndrome; Spondylitis, Ankylosing; Arthritis, Psoriatic; Behcet Syndrome; Immune System Diseases; Oral Ulcer; Psoriasis Phosphodiesterase 4 inhibitor

Small molecule

Approved

DERMATOLOGY; IMMUNE SYSTEM; OTHER; RHEUMATOLOGY

ORAL; UNKNOWN

Lupus Erythematosus, Discoid; Uveitis; Acne Vulgaris; Alcoholism; Arthritis, Rheumatoid; Colitis, Ulcerative; Dermatitis; Dermatitis, Allergic Contact; Dermatitis, Atopic; Dermatomyositis; Eczema; Erythema Multiforme; Gout; Hidradenitis Suppurativa; Lichen Planus; Lichen Planus, Oral; Prostatitis; Rosacea; Vitiligo; Influenza, Human; Pneumonia; Severe Acute Respiratory Syndrome; Spondylitis, Ankylosing; Arthritis, Psoriatic; Behcet Syndrome; Immune System Diseases; Oral Ulcer; Psoriasis

Phosphodiesterase 4 inhibitor


Small molecule Approved Unknown Unknown Hematologic Neoplasms; Gaucher Disease Unknown


Small molecule Approved HEMATOLOGY INTRAVENOUS Adenocarcinoma; Blast Crisis; Carcinoma, Non-Small-Cell Lung; Hematologic Neoplasms; Hodgkin Disease; Leukemia; Liver Neoplasms; Lymphoma; Lymphoma, Follicular; Mycosis Fungoides; Sarcoma; Small Cell Lung Carcinoma; Urinary Bladder Neoplasms; Burkitt Lymphoma; Carcinoma; Carcinoma, Endometrioid; Cystadenoma, Serous; Fallopian Tube Neoplasms; Glioblastoma; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid, Acute; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous; Mesothelioma; Multiple Myeloma; Myelodysplastic Syndromes; Peritoneal Neoplasms; Thymoma; Uveal Melanoma; Lymphoma, T-Cell; Lymphoma, T-Cell, Peripheral; Neoplasms Histone deacetylase inhibitor

Small molecule

Approved

HEMATOLOGY

INTRAVENOUS

Adenocarcinoma; Blast Crisis; Carcinoma, Non-Small-Cell Lung; Hematologic Neoplasms; Hodgkin Disease; Leukemia; Liver Neoplasms; Lymphoma; Lymphoma, Follicular; Mycosis Fungoides; Sarcoma; Small Cell Lung Carcinoma; Urinary Bladder Neoplasms; Burkitt Lymphoma; Carcinoma; Carcinoma, Endometrioid; Cystadenoma, Serous; Fallopian Tube Neoplasms; Glioblastoma; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid, Acute; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous; Mesothelioma; Multiple Myeloma; Myelodysplastic Syndromes; Peritoneal Neoplasms; Thymoma; Uveal Melanoma; Lymphoma, T-Cell; Lymphoma, T-Cell, Peripheral; Neoplasms

Histone deacetylase inhibitor


Small molecule Approved OTHER ORAL Central Nervous System Neoplasms; Cystadenocarcinoma, Serous; Esophageal Neoplasms; Head and Neck Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Hypertension, Pulmonary; Inflammatory Breast Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Neoplasm Metastasis; Neuroendocrine Tumors; Rhabdomyosarcoma; Squamous Cell Carcinoma of Head and Neck; Uterine Neoplasms; Bile Duct Neoplasms; Biliary Tract Neoplasms; Carcinoma, Ovarian Epithelial; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Carcinosarcoma; Cholangiocarcinoma; Colorectal Neoplasms; Fallopian Tube Neoplasms; Glioblastoma; Glioma; Hemangiosarcoma; Leiomyosarcoma; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma, T-Cell, Peripheral; Melanoma; Mesothelioma; Myelodysplastic Syndromes; Neoplasms, Germ Cell and Embryonal; Osteosarcoma; Peritoneal Neoplasms; Pheochromocytoma; Sarcoma; Sarcoma, Ewing; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Uveal Melanoma; Carcinoma; Carcinoma, Non-Small-Cell Lung; Endometrial Neoplasms; Lung Neoplasms; Prostatic Neoplasms; Small Cell Lung Carcinoma; Stomach Neoplasms; Breast Neoplasms; Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant PARP 1, 2 and 3 inhibitor

Small molecule

Approved

OTHER

ORAL

Central Nervous System Neoplasms; Cystadenocarcinoma, Serous; Esophageal Neoplasms; Head and Neck Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Hypertension, Pulmonary; Inflammatory Breast Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Neoplasm Metastasis; Neuroendocrine Tumors; Rhabdomyosarcoma; Squamous Cell Carcinoma of Head and Neck; Uterine Neoplasms; Bile Duct Neoplasms; Biliary Tract Neoplasms; Carcinoma, Ovarian Epithelial; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Carcinosarcoma; Cholangiocarcinoma; Colorectal Neoplasms; Fallopian Tube Neoplasms; Glioblastoma; Glioma; Hemangiosarcoma; Leiomyosarcoma; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma, T-Cell, Peripheral; Melanoma; Mesothelioma; Myelodysplastic Syndromes; Neoplasms, Germ Cell and Embryonal; Osteosarcoma; Peritoneal Neoplasms; Pheochromocytoma; Sarcoma; Sarcoma, Ewing; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Uveal Melanoma; Carcinoma; Carcinoma, Non-Small-Cell Lung; Endometrial Neoplasms; Lung Neoplasms; Prostatic Neoplasms; Small Cell Lung Carcinoma; Stomach Neoplasms; Breast Neoplasms; Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant

PARP 1, 2 and 3 inhibitor


Small molecule Approved Unknown Unknown Carcinoma, Non-Small-Cell Lung; Idiopathic Pulmonary Fibrosis; Lung Diseases, Interstitial; Scleroderma, Systemic Fibroblast growth factor receptor inhibitor


Antibody Approved CANCER INJECTION Burkitt Lymphoma; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Multiple Myeloma; Hematologic Neoplasms; Leukemia, Biphenotypic, Acute; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Leukemia; Neoplasms; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma B-lymphocyte antigen CD19 cross-linking agent


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Sleep Apnea Syndromes; Tobacco Use Disorder; Alcoholism; Alzheimer Disease; Autistic Disorder; Opioid-Related Disorders; Restless Legs Syndrome; Sleep Wake Disorders; Smoking Cessation; Delirium; Sleep Initiation and Maintenance Disorders Orexin receptor antagonist


Small molecule Approved Unknown Unknown Communicable Diseases; Urinary Tract Infections; Infections; Lung Diseases; Pneumonia; Pneumonia, Ventilator-Associated; Pyelonephritis Unknown


Small molecule Approved Unknown Unknown Intraabdominal Infections; Urinary Tract Infections Bacterial penicillin-binding protein inhibitor


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Acute Kidney Injury; Crohn Disease; Diabetic Neuropathies; Epilepsy; Inflammatory Bowel Diseases; Ascites; Colitis, Ulcerative; Depressive Disorder, Major; Familial Primary Pulmonary Hypertension; Glycogen Storage Disease Type I; Hypertension, Portal; Hypoglycemia; Hyponatremia; Inappropriate ADH Syndrome; Kidney Calculi; Kidney Diseases; Kidney Failure, Chronic; Neoplasms; Polycystic Kidney, Autosomal Dominant; Polycystic Ovary Syndrome; Prediabetic State; ST Elevation Myocardial Infarction; Cardiotoxicity; Diabetes, Gestational; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Insulin Resistance; Metabolic Syndrome; Myocardial Infarction; Non-alcoholic Fatty Liver Disease; Severe Acute Respiratory Syndrome; Shock; Diabetes Mellitus; Diabetes Mellitus, Type 2; Heart Failure; Renal Insufficiency, Chronic Sodium/glucose cotransporter 2 inhibitor

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER

ORAL

Acute Kidney Injury; Crohn Disease; Diabetic Neuropathies; Epilepsy; Inflammatory Bowel Diseases; Ascites; Colitis, Ulcerative; Depressive Disorder, Major; Familial Primary Pulmonary Hypertension; Glycogen Storage Disease Type I; Hypertension, Portal; Hypoglycemia; Hyponatremia; Inappropriate ADH Syndrome; Kidney Calculi; Kidney Diseases; Kidney Failure, Chronic; Neoplasms; Polycystic Kidney, Autosomal Dominant; Polycystic Ovary Syndrome; Prediabetic State; ST Elevation Myocardial Infarction; Cardiotoxicity; Diabetes, Gestational; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Insulin Resistance; Metabolic Syndrome; Myocardial Infarction; Non-alcoholic Fatty Liver Disease; Severe Acute Respiratory Syndrome; Shock; Diabetes Mellitus; Diabetes Mellitus, Type 2; Heart Failure; Renal Insufficiency, Chronic

Sodium/glucose cotransporter 2 inhibitor


Small molecule Approved Unknown Unknown Liver Diseases; Asthma; Pulmonary Disease, Chronic Obstructive; Lung Diseases, Obstructive Unknown


Small molecule Approved Unknown Unknown Unknown Unknown


Protein Approved DIABETES DRUGS & ENDOCRINOLOGY INJECTION Diabetes Mellitus, Type 1; Heart Failure; Diabetes Mellitus; Diabetes Mellitus, Type 2 Glucagon-like peptide 1 receptor agonist


Small molecule Approved OTHER INTRAVENOUS Influenza, Human Neuraminidase inhibitor


Protein Approved NEUROLOGY DRUGS & NERVOUS SYSTEM INJECTION Renal Insufficiency; Multiple Sclerosis, Relapsing-Remitting; Multiple Sclerosis; Neoplasms Interferon alpha/beta receptor agonist


Small molecule Approved Unknown Unknown Carcinoma, Non-Small-Cell Lung; Opioid-Related Disorders; Brain Injuries; Ileus; Constipation Unknown


Small molecule Approved Unknown Unknown HIV Infections; Cerebral Infarction; Thrombosis Unknown


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Aging; Alzheimer Disease; Brain Neoplasms; Lupus Nephritis; Myocardial Ischemia; Pancreatic Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Reperfusion Injury; Albuminuria; Amyloidosis, Familial; Breast Neoplasms; Cystinuria; Depressive Disorder; Diabetic Nephropathies; Diabetic Neuropathies; Fabry Disease; Heart Failure, Diastolic; Hypertension, Pulmonary; Hyperuricemia; Inflammatory Bowel Diseases; Liver Cirrhosis; Metabolic Syndrome; Motor Activity; Myocardial Infarction; Obesity; Weight Loss; Acute Kidney Injury; Atrial Fibrillation; Coronary Disease; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Fatty Liver; Glomerulonephritis, IGA; Insulin Resistance; Kidney Failure, Chronic; Non-alcoholic Fatty Liver Disease; Polycystic Ovary Syndrome; Renal Insufficiency; Severe Acute Respiratory Syndrome; ST Elevation Myocardial Infarction; Diabetes Mellitus; Diabetes Mellitus, Type 2; Heart Failure; Renal Insufficiency, Chronic Sodium/glucose cotransporter 2 inhibitor

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER

ORAL

Aging; Alzheimer Disease; Brain Neoplasms; Lupus Nephritis; Myocardial Ischemia; Pancreatic Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Reperfusion Injury; Albuminuria; Amyloidosis, Familial; Breast Neoplasms; Cystinuria; Depressive Disorder; Diabetic Nephropathies; Diabetic Neuropathies; Fabry Disease; Heart Failure, Diastolic; Hypertension, Pulmonary; Hyperuricemia; Inflammatory Bowel Diseases; Liver Cirrhosis; Metabolic Syndrome; Motor Activity; Myocardial Infarction; Obesity; Weight Loss; Acute Kidney Injury; Atrial Fibrillation; Coronary Disease; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Fatty Liver; Glomerulonephritis, IGA; Insulin Resistance; Kidney Failure, Chronic; Non-alcoholic Fatty Liver Disease; Polycystic Ovary Syndrome; Renal Insufficiency; Severe Acute Respiratory Syndrome; ST Elevation Myocardial Infarction; Diabetes Mellitus; Diabetes Mellitus, Type 2; Heart Failure; Renal Insufficiency, Chronic

Sodium/glucose cotransporter 2 inhibitor


Antibody Approved DERMATOLOGY UNKNOWN Astrocytoma; Bile Duct Neoplasms; Carcinoma, Basal Cell; Carcinoma, Intraductal, Noninfiltrating; Glioma; Histiocytoma, Malignant Fibrous; HIV Infections; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Lymphoid; Lymphoma, Mantle-Cell; Lymphoma, T-Cell, Cutaneous; Neuroblastoma; Papillomavirus Infections; Rhabdomyosarcoma; Sarcoma, Ewing; Sarcoma, Synovial; Smoldering Multiple Myeloma; Uterine Neoplasms; Adenocarcinoma; Adenocarcinoma, Follicular; Adrenal Cortex Neoplasms; Anus Neoplasms; Breast Neoplasms, Male; Carcinoid Tumor; Carcinoma, Adenoid Cystic; Carcinoma in Situ; Carcinoma, Medullary; Carcinoma, Neuroendocrine; Carcinoma, Pancreatic Ductal; Carcinosarcoma; Cholangiocarcinoma; Colonic Neoplasms; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Gastrointestinal Stromal Tumors; Genital Neoplasms, Female; Gestational Trophoblastic Disease; Glioblastoma; Gliosarcoma; Granuloma, Lethal Midline; Hemangiosarcoma; Hematologic Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Inflammatory Breast Neoplasms; Kidney Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Leukoencephalopathy, Progressive Multifocal; Leukoplakia, Oral; Liver Neoplasms; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Meningeal Carcinomatosis; Meningeal Neoplasms; Meningioma; Mouth Neoplasms; Mycosis Fungoides; Myelodysplastic Syndromes; Nasopharyngeal Carcinoma; Neoplasm Metastasis; Neurilemmoma; Neuroendocrine Tumors; Oropharyngeal Neoplasms; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Papilloma; Paraganglioma; Parotid Neoplasms; Penile Neoplasms; Peritoneal Neoplasms; Pneumonia, Viral; Rectal Neoplasms; Retroviridae Infections; Salivary Gland Neoplasms; Sarcoma; Sarcoma, Alveolar Soft Part; Sarcoma, Kaposi; Severe Acute Respiratory Syndrome; Sezary Syndrome; Skin Neoplasms; Thymoma; Thymus Neoplasms; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Uveal Melanoma; Vulvar Neoplasms; Waldenstrom Macroglobulinemia; Adenocarcinoma of Lung; Biliary Tract Neoplasms; Brain Neoplasms; Breast Carcinoma In Situ; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Merkel Cell; Colorectal Neoplasms; Esophageal Neoplasms; Head and Neck Neoplasms; Lung Neoplasms; Mesothelioma; Multiple Myeloma; Nasopharyngeal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Stomach Neoplasms; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Endometrial Neoplasms; Hodgkin Disease; Melanoma; Neoplasms; Squamous Cell Carcinoma of Head and Neck Programmed cell death protein 1 inhibitor

Antibody

Approved

DERMATOLOGY

UNKNOWN

Astrocytoma; Bile Duct Neoplasms; Carcinoma, Basal Cell; Carcinoma, Intraductal, Noninfiltrating; Glioma; Histiocytoma, Malignant Fibrous; HIV Infections; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Lymphoid; Lymphoma, Mantle-Cell; Lymphoma, T-Cell, Cutaneous; Neuroblastoma; Papillomavirus Infections; Rhabdomyosarcoma; Sarcoma, Ewing; Sarcoma, Synovial; Smoldering Multiple Myeloma; Uterine Neoplasms; Adenocarcinoma; Adenocarcinoma, Follicular; Adrenal Cortex Neoplasms; Anus Neoplasms; Breast Neoplasms, Male; Carcinoid Tumor; Carcinoma, Adenoid Cystic; Carcinoma in Situ; Carcinoma, Medullary; Carcinoma, Neuroendocrine; Carcinoma, Pancreatic Ductal; Carcinosarcoma; Cholangiocarcinoma; Colonic Neoplasms; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Gastrointestinal Stromal Tumors; Genital Neoplasms, Female; Gestational Trophoblastic Disease; Glioblastoma; Gliosarcoma; Granuloma, Lethal Midline; Hemangiosarcoma; Hematologic Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Inflammatory Breast Neoplasms; Kidney Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Leukoencephalopathy, Progressive Multifocal; Leukoplakia, Oral; Liver Neoplasms; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Meningeal Carcinomatosis; Meningeal Neoplasms; Meningioma; Mouth Neoplasms; Mycosis Fungoides; Myelodysplastic Syndromes; Nasopharyngeal Carcinoma; Neoplasm Metastasis; Neurilemmoma; Neuroendocrine Tumors; Oropharyngeal Neoplasms; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Papilloma; Paraganglioma; Parotid Neoplasms; Penile Neoplasms; Peritoneal Neoplasms; Pneumonia, Viral; Rectal Neoplasms; Retroviridae Infections; Salivary Gland Neoplasms; Sarcoma; Sarcoma, Alveolar Soft Part; Sarcoma, Kaposi; Severe Acute Respiratory Syndrome; Sezary Syndrome; Skin Neoplasms; Thymoma; Thymus Neoplasms; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Uveal Melanoma; Vulvar Neoplasms; Waldenstrom Macroglobulinemia; Adenocarcinoma of Lung; Biliary Tract Neoplasms; Brain Neoplasms; Breast Carcinoma In Situ; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Merkel Cell; Colorectal Neoplasms; Esophageal Neoplasms; Head and Neck Neoplasms; Lung Neoplasms; Mesothelioma; Multiple Myeloma; Nasopharyngeal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Stomach Neoplasms; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Endometrial Neoplasms; Hodgkin Disease; Melanoma; Neoplasms; Squamous Cell Carcinoma of Head and Neck

Programmed cell death protein 1 inhibitor


Small molecule Approved Unknown Unknown Lung Neoplasms; Carcinoma, Non-Small-Cell Lung Epidermal growth factor receptor erbB1 inhibitor


Antibody Approved RESPIRATORY INJECTION Diffuse Intrinsic Pontine Glioma; Fallopian Tube Neoplasms; Genital Neoplasms, Female; Hepatitis C; Hepatitis D; HIV Infections; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Lymphoma, Mantle-Cell; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous; Mycosis Fungoides; Neoplasm Metastasis; Nerve Sheath Neoplasms; Neuroblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retroperitoneal Neoplasms; Rhabdomyosarcoma; Sarcoma, Ewing; Sarcoma, Synovial; Sepsis; Sezary Syndrome; ST Elevation Myocardial Infarction; Triple Negative Breast Neoplasms; Adrenal Cortex Neoplasms; Basal Cell Nevus Syndrome; Biliary Tract Neoplasms; Carcinoid Tumor; Carcinoma; Carcinoma, Basal Cell; Carcinoma, Large Cell; Carcinoma, Merkel Cell; Carcinoma, Neuroendocrine; Carcinoma, Pancreatic Ductal; Carcinoma, Small Cell; Carcinosarcoma; Cell- and Tissue-Based Therapy; Cholangiocarcinoma; Chordoma; Colonic Neoplasms; Craniopharyngioma; Endometrial Neoplasms; Gastrointestinal Stromal Tumors; Glioma; Gliosarcoma; Hematologic Neoplasms; Hepatitis B, Chronic; Histiocytoma, Malignant Fibrous; Inflammatory Breast Neoplasms; Leiomyosarcoma; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Leukoplakia, Oral; Liposarcoma; Liver Neoplasms; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Meningioma; Mesothelioma, Malignant; Myelodysplastic Syndromes; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuroendocrine Tumors; Oligodendroglioma; Oropharyngeal Neoplasms; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Paraganglioma; Peritoneal Neoplasms; Pituitary Neoplasms; Pneumonia, Viral; Prostatic Neoplasms; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Retroviridae Infections; Salivary Gland Neoplasms; Sarcoma, Kaposi; Severe Acute Respiratory Syndrome; Small Cell Lung Carcinoma; Thyroid Neoplasms; Uterine Cervical Neoplasms; Uveal Melanoma; Adenocarcinoma; Adenocarcinoma of Lung; Brain Neoplasms; Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Esophageal Neoplasms; Glioblastoma; Head and Neck Neoplasms; Kidney Neoplasms; Lung Neoplasms; Lymphoma; Multiple Myeloma; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Skin Neoplasms; Stomach Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Colorectal Neoplasms; Hodgkin Disease; Melanoma; Mesothelioma; Neoplasms; Squamous Cell Carcinoma of Head and Neck Programmed cell death protein 1 inhibitor

Antibody

Approved

RESPIRATORY

INJECTION

Diffuse Intrinsic Pontine Glioma; Fallopian Tube Neoplasms; Genital Neoplasms, Female; Hepatitis C; Hepatitis D; HIV Infections; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Lymphoma, Mantle-Cell; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous; Mycosis Fungoides; Neoplasm Metastasis; Nerve Sheath Neoplasms; Neuroblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Retroperitoneal Neoplasms; Rhabdomyosarcoma; Sarcoma, Ewing; Sarcoma, Synovial; Sepsis; Sezary Syndrome; ST Elevation Myocardial Infarction; Triple Negative Breast Neoplasms; Adrenal Cortex Neoplasms; Basal Cell Nevus Syndrome; Biliary Tract Neoplasms; Carcinoid Tumor; Carcinoma; Carcinoma, Basal Cell; Carcinoma, Large Cell; Carcinoma, Merkel Cell; Carcinoma, Neuroendocrine; Carcinoma, Pancreatic Ductal; Carcinoma, Small Cell; Carcinosarcoma; Cell- and Tissue-Based Therapy; Cholangiocarcinoma; Chordoma; Colonic Neoplasms; Craniopharyngioma; Endometrial Neoplasms; Gastrointestinal Stromal Tumors; Glioma; Gliosarcoma; Hematologic Neoplasms; Hepatitis B, Chronic; Histiocytoma, Malignant Fibrous; Inflammatory Breast Neoplasms; Leiomyosarcoma; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Leukoplakia, Oral; Liposarcoma; Liver Neoplasms; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Meningioma; Mesothelioma, Malignant; Myelodysplastic Syndromes; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuroendocrine Tumors; Oligodendroglioma; Oropharyngeal Neoplasms; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Paraganglioma; Peritoneal Neoplasms; Pituitary Neoplasms; Pneumonia, Viral; Prostatic Neoplasms; Pulmonary Disease, Chronic Obstructive; Rectal Neoplasms; Retroviridae Infections; Salivary Gland Neoplasms; Sarcoma, Kaposi; Severe Acute Respiratory Syndrome; Small Cell Lung Carcinoma; Thyroid Neoplasms; Uterine Cervical Neoplasms; Uveal Melanoma; Adenocarcinoma; Adenocarcinoma of Lung; Brain Neoplasms; Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Esophageal Neoplasms; Glioblastoma; Head and Neck Neoplasms; Kidney Neoplasms; Lung Neoplasms; Lymphoma; Multiple Myeloma; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Skin Neoplasms; Stomach Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Colorectal Neoplasms; Hodgkin Disease; Melanoma; Mesothelioma; Neoplasms; Squamous Cell Carcinoma of Head and Neck

Programmed cell death protein 1 inhibitor


Small molecule Approved Unknown Unknown Severe Acute Respiratory Syndrome; Aortic Valve Insufficiency; Cardiomyopathy, Hypertrophic; Essential Hypertension; Peripheral Arterial Disease; Chagas Cardiomyopathy; Hypertension; Hypertension, Pulmonary; Myocardial Infarction; ST Elevation Myocardial Infarction; Heart Failure Neprilysin inhibitor


Small molecule Approved Unknown Unknown Hyperkalemia Potassium chelating agent


Small molecule Approved Unknown Unknown Neoplasms; Pulmonary Disease, Chronic Obstructive; Carcinoma, Squamous Cell; Colonic Neoplasms; Nasopharyngeal Neoplasms; Pancreatic Neoplasms; Rectal Neoplasms; Small Cell Lung Carcinoma; Stomach Neoplasms; Colorectal Neoplasms Thymidine phosphorylase inhibitor


Small molecule Approved Unknown ORAL Smith-Lemli-Opitz Syndrome; Fatty Liver; Digestive System Diseases; Liver Diseases; Metabolism, Inborn Errors; Peroxisomal Disorders Unknown


Small molecule Approved Unknown INHALATION Status Asthmaticus; Pulmonary Disease, Chronic Obstructive Unknown


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved Unknown Unknown Postoperative Nausea and Vomiting; Nausea Unknown

Small molecule

Approved

Unknown

INTRAVENOUS

Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Sarcoma, Ewing; Breast Neoplasms; Carcinoma, Ovarian Epithelial; Chondrosarcoma, Mesenchymal; Endocrine Gland Neoplasms; Fallopian Tube Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Liposarcoma, Myxoid; Meningioma; Mesothelioma; Paget Disease, Extramammary; Pancreatic Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Soft Tissue Neoplasms; Leiomyosarcoma; Liposarcoma; Neoplasms; Ovarian Neoplasms; Sarcoma

DNA inhibitor


Small molecule Approved Unknown ORAL Alcoholism; Borderline Personality Disorder; Alzheimer Disease; Bipolar Disorder; Depressive Disorder; Mental Disorders; Psychomotor Agitation; Sleep Wake Disorders; Stress Disorders, Post-Traumatic; Depressive Disorder, Major; Psychotic Disorders; Schizophrenia Dopamine D2 receptor partial agonist


Small molecule Approved Unknown Unknown Carcinoma, Hepatocellular; Esophageal Neoplasms; Graft vs Host Disease; Liver Diseases; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Carcinoma, Basal Cell; Leukemia; Medulloblastoma; Multiple Myeloma; Neoplasms Unknown


Small molecule Approved Unknown Unknown Carcinoma, Non-Small-Cell Lung; Neoplasms; Breast Neoplasms; Cholangiocarcinoma; Colonic Neoplasms; Pancreatic Neoplasms; Rectal Neoplasms; Stomach Neoplasms; Urinary Bladder Neoplasms; Colorectal Neoplasms Unknown