DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 139


Small molecule Approved OTHER OPHTHALMIC Alopecia Areata; Meniere Disease; Vitiligo; Glaucoma; Glaucoma, Open-Angle; Hypertension; Ocular Hypertension Prostanoid FP receptor agonist


Small molecule Approved Unknown Unknown Hepatopulmonary Syndrome; Hypotension, Orthostatic; Ischemic Stroke; Ascites; Hypotension; Shock, Septic; Spinal Cord Injuries; Cardiovascular Diseases Unknown


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Cardiovascular Diseases; Heart Failure; Hypertension; Myocardial Infarction; Ventricular Dysfunction, Left Angiotensin-converting enzyme inhibitor


Small molecule Approved Unknown Unknown Carcinoid Tumor; Desmoplastic Small Round Cell Tumor; Diffuse Intrinsic Pontine Glioma; Endometrial Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Liver Neoplasms; Mesothelioma; Oligodendroglioma; Pulmonary Disease, Chronic Obstructive; Adenocarcinoma; Astrocytoma; Bile Duct Neoplasms; Biliary Tract Neoplasms; Bone Neoplasms; Carcinoma; Carcinoma, Islet Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Glioblastoma; Glioma; Gliosarcoma; Head and Neck Neoplasms; Hemangiosarcoma; Kidney Neoplasms; Leukemia; Lymphoma; Lymphoma, Non-Hodgkin; Medulloblastoma; Ovarian Neoplasms; Paraganglioma; Peritoneal Neoplasms; Pinealoma; Rhabdomyosarcoma; Sarcoma; Wilms Tumor; Brain Neoplasms; Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Neuroendocrine; Carcinoma, Pancreatic Ductal; Cholangiocarcinoma; Choroid Plexus Neoplasms; Colonic Neoplasms; Colorectal Neoplasms; Esophageal Neoplasms; Ganglioneuroblastoma; Hepatoblastoma; Lung Neoplasms; Neoplasm Metastasis; Neuroblastoma; Pancreatic Neoplasms; Rectal Neoplasms; Sarcoma, Ewing; Small Cell Lung Carcinoma; Stomach Neoplasms; Uterine Cervical Neoplasms; Neoplasms Unknown

Small molecule

Approved

Unknown

Carcinoid Tumor; Desmoplastic Small Round Cell Tumor; Diffuse Intrinsic Pontine Glioma; Endometrial Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Liver Neoplasms; Mesothelioma; Oligodendroglioma; Pulmonary Disease, Chronic Obstructive; Adenocarcinoma; Astrocytoma; Bile Duct Neoplasms; Biliary Tract Neoplasms; Bone Neoplasms; Carcinoma; Carcinoma, Islet Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Fallopian Tube Neoplasms; Gallbladder Neoplasms; Glioblastoma; Glioma; Gliosarcoma; Head and Neck Neoplasms; Hemangiosarcoma; Kidney Neoplasms; Leukemia; Lymphoma; Lymphoma, Non-Hodgkin; Medulloblastoma; Ovarian Neoplasms; Paraganglioma; Peritoneal Neoplasms; Pinealoma; Rhabdomyosarcoma; Sarcoma; Wilms Tumor; Brain Neoplasms; Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Neuroendocrine; Carcinoma, Pancreatic Ductal; Cholangiocarcinoma; Choroid Plexus Neoplasms; Colonic Neoplasms; Colorectal Neoplasms; Esophageal Neoplasms; Ganglioneuroblastoma; Hepatoblastoma; Lung Neoplasms; Neoplasm Metastasis; Neuroblastoma; Pancreatic Neoplasms; Rectal Neoplasms; Sarcoma, Ewing; Small Cell Lung Carcinoma; Stomach Neoplasms; Uterine Cervical Neoplasms; Neoplasms

Unknown


Small molecule Approved OTHER INJECTION Bacterial Infections Bacterial DNA gyrase inhibitor


Small molecule Approved Unknown Unknown Depressive Disorder, Major; Diabetes Mellitus, Type 2; Head and Neck Neoplasms; Lupus Erythematosus, Systemic; Asthma; Cardiovascular Diseases; Heart Diseases; HIV Infections; Hypertension, Pulmonary; Intermittent Claudication; Peripheral Vascular Diseases; Pneumonia, Viral; Polycythemia Vera; Pregnancy; Respiratory Insufficiency; Scleroderma, Systemic; Venous Thromboembolism; Acute Coronary Syndrome; Angina, Stable; Aortic Valve Stenosis; Arteriosclerosis; Atherosclerosis; Atrial Fibrillation; Brain Infarction; Carotid Stenosis; Coronary Disease; Gastrointestinal Hemorrhage; Heart Defects, Congenital; Heart Failure; Hemorrhage; Influenza, Human; Intracranial Aneurysm; Intracranial Arteriosclerosis; Ischemia; Ischemic Attack, Transient; Ischemic Stroke; Kidney Failure, Chronic; Macular Degeneration; Myocardial Infarction; Myocardial Ischemia; Pancreatic Neoplasms; Peripheral Arterial Disease; Pneumonia; Pulmonary Disease, Chronic Obstructive; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; ST Elevation Myocardial Infarction; Stroke; Thrombophilia; Vascular Diseases; Thrombosis Unknown

Small molecule

Approved

Unknown

Depressive Disorder, Major; Diabetes Mellitus, Type 2; Head and Neck Neoplasms; Lupus Erythematosus, Systemic; Asthma; Cardiovascular Diseases; Heart Diseases; HIV Infections; Hypertension, Pulmonary; Intermittent Claudication; Peripheral Vascular Diseases; Pneumonia, Viral; Polycythemia Vera; Pregnancy; Respiratory Insufficiency; Scleroderma, Systemic; Venous Thromboembolism; Acute Coronary Syndrome; Angina, Stable; Aortic Valve Stenosis; Arteriosclerosis; Atherosclerosis; Atrial Fibrillation; Brain Infarction; Carotid Stenosis; Coronary Disease; Gastrointestinal Hemorrhage; Heart Defects, Congenital; Heart Failure; Hemorrhage; Influenza, Human; Intracranial Aneurysm; Intracranial Arteriosclerosis; Ischemia; Ischemic Attack, Transient; Ischemic Stroke; Kidney Failure, Chronic; Macular Degeneration; Myocardial Infarction; Myocardial Ischemia; Pancreatic Neoplasms; Peripheral Arterial Disease; Pneumonia; Pulmonary Disease, Chronic Obstructive; Renal Insufficiency, Chronic; Severe Acute Respiratory Syndrome; ST Elevation Myocardial Infarction; Stroke; Thrombophilia; Vascular Diseases; Thrombosis

Unknown


Small molecule Approved OTHER TOPICAL Skin Diseases Glucocorticoid receptor agonist


Small molecule Approved Unknown Unknown Desmoid Tumors; Ovarian Neoplasms; Prostatic Neoplasms, Castration-Resistant; Severe Acute Respiratory Syndrome; Breast Neoplasms; Fractures, Bone; Mastodynia; Neoplasms; Prostatic Intraepithelial Neoplasia Unknown


Small molecule Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER; RHEUMATOLOGY ORAL Breast Diseases; Breast Neoplasms; Bronchiolitis Obliterans Syndrome; Hemosiderosis; HIV Infections; Melanoma; Neoplasms; IgA Vasculitis; Lupus Erythematosus, Systemic; Lymphoproliferative Disorders; Multiple Myeloma; Pemphigoid, Bullous; Prostatic Neoplasms, Castration-Resistant; Sjogren's Syndrome; Smoldering Multiple Myeloma; Uveitis; Central Nervous System Neoplasms; Lupus Nephritis; Myasthenia Gravis; Polymyalgia Rheumatica; Severe Acute Respiratory Syndrome; Arthritis, Psoriatic; Arthritis, Rheumatoid Dihydroorotate dehydrogenase inhibitor

Small molecule

Approved

DIABETES DRUGS & ENDOCRINOLOGY; OTHER; RHEUMATOLOGY

ORAL

Breast Diseases; Breast Neoplasms; Bronchiolitis Obliterans Syndrome; Hemosiderosis; HIV Infections; Melanoma; Neoplasms; IgA Vasculitis; Lupus Erythematosus, Systemic; Lymphoproliferative Disorders; Multiple Myeloma; Pemphigoid, Bullous; Prostatic Neoplasms, Castration-Resistant; Sjogren's Syndrome; Smoldering Multiple Myeloma; Uveitis; Central Nervous System Neoplasms; Lupus Nephritis; Myasthenia Gravis; Polymyalgia Rheumatica; Severe Acute Respiratory Syndrome; Arthritis, Psoriatic; Arthritis, Rheumatoid

Dihydroorotate dehydrogenase inhibitor


Small molecule Approved CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER ORAL Cardiovascular Diseases; Brain Injuries; Pain; Severe Acute Respiratory Syndrome; Atherosclerosis; Breast Neoplasms; Coronary Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Essential Hypertension; Hypercholesterolemia; Hypertension, Renovascular; Proteinuria; Renal Artery Obstruction; Angina Pectoris; Diabetes Mellitus; Heart Failure; Hypertension; Myocardial Infarction; Stroke Type-1 angiotensin II receptor antagonist

Small molecule

Approved

CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER

ORAL

Cardiovascular Diseases; Brain Injuries; Pain; Severe Acute Respiratory Syndrome; Atherosclerosis; Breast Neoplasms; Coronary Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Essential Hypertension; Hypercholesterolemia; Hypertension, Renovascular; Proteinuria; Renal Artery Obstruction; Angina Pectoris; Diabetes Mellitus; Heart Failure; Hypertension; Myocardial Infarction; Stroke

Type-1 angiotensin II receptor antagonist


Small molecule Approved Unknown Unknown Glioma; Hepatitis C; Acidosis, Lactic; Lipodystrophy; Sarcoma, Kaposi; Acquired Immunodeficiency Syndrome; HIV Infections; Tuberculosis; Virus Diseases Unknown


Small molecule Approved CANCER; OTHER INTRAVENOUS; ORAL Cytomegalovirus Infections; Desmoplastic Small Round Cell Tumor; Ependymoma; Fallopian Tube Neoplasms; Meningitis, Aseptic; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Wilms Tumor; Biliary Tract Neoplasms; Brain Diseases; Brain Stem Neoplasms; Breast Neoplasms; Carcinoid Tumor; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Neuroendocrine; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Hereditary Breast and Ovarian Cancer Syndrome; Leiomyosarcoma; Leukemia; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Medulloblastoma; Myelodysplastic Syndromes; Neuroectodermal Tumors, Primitive, Peripheral; Neuroendocrine Tumors; Neurofibromatosis 1; Ovarian Neoplasms; Pancreatic Neoplasms; Pheochromocytoma; Pinealoma; Pituitary Neoplasms; Rectal Neoplasms; Retinoblastoma; Rhabdomyosarcoma; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Sarcoma; Skin Neoplasms; Small Cell Lung Carcinoma; Spinal Cord Neoplasms; Uveal Melanoma; Astrocytoma; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Choroid Plexus Neoplasms; Diffuse Intrinsic Pontine Glioma; Ganglioneuroblastoma; Gliosarcoma; Melanoma; Neoplasm Metastasis; Neuroblastoma; Oligodendroglioma; Optic Nerve Glioma; Paraganglioma; Sarcoma, Ewing; Glioblastoma; Glioma; Neoplasms DNA inhibitor

Small molecule

Approved

CANCER; OTHER

INTRAVENOUS; ORAL

Cytomegalovirus Infections; Desmoplastic Small Round Cell Tumor; Ependymoma; Fallopian Tube Neoplasms; Meningitis, Aseptic; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Wilms Tumor; Biliary Tract Neoplasms; Brain Diseases; Brain Stem Neoplasms; Breast Neoplasms; Carcinoid Tumor; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Neuroendocrine; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Hereditary Breast and Ovarian Cancer Syndrome; Leiomyosarcoma; Leukemia; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Medulloblastoma; Myelodysplastic Syndromes; Neuroectodermal Tumors, Primitive, Peripheral; Neuroendocrine Tumors; Neurofibromatosis 1; Ovarian Neoplasms; Pancreatic Neoplasms; Pheochromocytoma; Pinealoma; Pituitary Neoplasms; Rectal Neoplasms; Retinoblastoma; Rhabdomyosarcoma; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Sarcoma; Skin Neoplasms; Small Cell Lung Carcinoma; Spinal Cord Neoplasms; Uveal Melanoma; Astrocytoma; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Choroid Plexus Neoplasms; Diffuse Intrinsic Pontine Glioma; Ganglioneuroblastoma; Gliosarcoma; Melanoma; Neoplasm Metastasis; Neuroblastoma; Oligodendroglioma; Optic Nerve Glioma; Paraganglioma; Sarcoma, Ewing; Glioblastoma; Glioma; Neoplasms

DNA inhibitor


Small molecule Approved Unknown Unknown Obesity; Renal Insufficiency, Chronic; Infections; Influenza in Birds; Thrombocytopenia; Influenza, Human; Pneumonia; Purpura, Thrombocytopenic, Idiopathic; Severe Acute Respiratory Syndrome; Virus Diseases Unknown


Small molecule Approved IMMUNE SYSTEM; OTHER ORAL Virus Diseases; Influenza, Human; Kidney Failure, Chronic Neuraminidase inhibitor


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; PEDIATRICS ORAL Neoplasms; Multiple Sclerosis; Aggression; Anxiety; Dementia; Depressive Disorder; Epilepsies, Partial; Neuralgia; Psychomotor Agitation; Schizophrenia; Epilepsy; Seizures Sodium channel alpha subunit blocker


Small molecule Approved EYE OPHTHALMIC Macular Degeneration; Retinitis Pigmentosa Unknown


Small molecule Approved Unknown Unknown Unknown Unknown


Small molecule Approved IMMUNE SYSTEM; OTHER ORAL Urinary Tract Infections; Bronchitis, Chronic; Infections; Pharyngitis; Tonsillitis Bacterial penicillin-binding protein inhibitor


Small molecule Approved IMMUNE SYSTEM; OTHER ORAL Hepatitis C; Hepatitis, Chronic; Insulin Resistance; Lymphoma; Parkinson Disease; Tuberculosis; Communicable Diseases; Hepatitis D; Lipodystrophy; Liver Cirrhosis, Biliary; Multiple Sclerosis; Acquired Immunodeficiency Syndrome; Severe Acute Respiratory Syndrome; Hepatitis B, Chronic; HIV Infections; Infections; Liver Diseases Human immunodeficiency virus type 1 reverse transcriptase inhibitor

Small molecule

Approved

IMMUNE SYSTEM; OTHER

ORAL

Hepatitis C; Hepatitis, Chronic; Insulin Resistance; Lymphoma; Parkinson Disease; Tuberculosis; Communicable Diseases; Hepatitis D; Lipodystrophy; Liver Cirrhosis, Biliary; Multiple Sclerosis; Acquired Immunodeficiency Syndrome; Severe Acute Respiratory Syndrome; Hepatitis B, Chronic; HIV Infections; Infections; Liver Diseases

Human immunodeficiency virus type 1 reverse transcriptase inhibitor


Small molecule Approved Unknown Unknown Depressive Disorder, Major; Fatigue Syndrome, Chronic; Idiopathic Pulmonary Fibrosis; Kidney Diseases; Nasopharyngeal Carcinoma; Castleman Disease; Hearing Loss, Sensorineural; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Colitis, Ulcerative; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Infections; Virus Diseases Unknown


Small molecule Approved Unknown Unknown Arthritis, Juvenile; Breast Neoplasms; Fatty Liver; Hepatitis B, Chronic; Hypertension, Pulmonary; Lymphoma; Neoplasms; Non-alcoholic Fatty Liver Disease; Asthma; Autistic Disorder; Child Development Disorders, Pervasive; Cystic Fibrosis; Dyspepsia; Eosinophilic Esophagitis; Neuralgia; Digestive System Diseases; Duodenal Ulcer; Esophageal Neoplasms; Esophagitis, Peptic; Gastritis; Gastroesophageal Reflux; Gastrointestinal Hemorrhage; Helicobacter Infections; Hemorrhage; Nausea; Osteoarthritis; Peptic Ulcer; Pre-Eclampsia; Stomach Ulcer; Ulcer Unknown

Small molecule

Approved

Unknown

Arthritis, Juvenile; Breast Neoplasms; Fatty Liver; Hepatitis B, Chronic; Hypertension, Pulmonary; Lymphoma; Neoplasms; Non-alcoholic Fatty Liver Disease; Asthma; Autistic Disorder; Child Development Disorders, Pervasive; Cystic Fibrosis; Dyspepsia; Eosinophilic Esophagitis; Neuralgia; Digestive System Diseases; Duodenal Ulcer; Esophageal Neoplasms; Esophagitis, Peptic; Gastritis; Gastroesophageal Reflux; Gastrointestinal Hemorrhage; Helicobacter Infections; Hemorrhage; Nausea; Osteoarthritis; Peptic Ulcer; Pre-Eclampsia; Stomach Ulcer; Ulcer

Unknown


Small molecule Approved EYE; OTHER OPHTHALMIC Exfoliation Syndrome; Glaucoma; Glaucoma, Open-Angle; Ocular Hypertension Prostanoid FP receptor agonist


Small molecule Approved Unknown Unknown Hepatitis; Hepatitis B, Chronic; Hepatitis C, Chronic; Hepatitis D; Liver Cirrhosis, Biliary; HIV Infections; Severe Acute Respiratory Syndrome; Virus Diseases Unknown


Small molecule Approved IMMUNE SYSTEM; OTHER; PEDIATRICS ORAL HIV Infections; Irritable Bowel Syndrome; Kidney Diseases; Liver Diseases; Bronchiolitis; Crohn Disease; Diabetes Mellitus, Type 2; Gastroenteritis; Hepatitis B, Chronic; Hepatitis C; Hepatitis C, Chronic; Malnutrition; Periodontitis; Sexually Transmitted Diseases; Tuberculosis; Arthritis, Rheumatoid; Brain Diseases; Clostridium Infections; Cryptosporidiosis; Dyspepsia; Enterocolitis, Pseudomembranous; Helicobacter Infections; Influenza, Human; Peritonitis; Respiratory Tract Diseases; Severe Acute Respiratory Syndrome; Amebiasis; Diarrhea Pyruvate:ferredoxin oxidoreductase inhibitor

Small molecule

Approved

IMMUNE SYSTEM; OTHER; PEDIATRICS

ORAL

HIV Infections; Irritable Bowel Syndrome; Kidney Diseases; Liver Diseases; Bronchiolitis; Crohn Disease; Diabetes Mellitus, Type 2; Gastroenteritis; Hepatitis B, Chronic; Hepatitis C; Hepatitis C, Chronic; Malnutrition; Periodontitis; Sexually Transmitted Diseases; Tuberculosis; Arthritis, Rheumatoid; Brain Diseases; Clostridium Infections; Cryptosporidiosis; Dyspepsia; Enterocolitis, Pseudomembranous; Helicobacter Infections; Influenza, Human; Peritonitis; Respiratory Tract Diseases; Severe Acute Respiratory Syndrome; Amebiasis; Diarrhea

Pyruvate:ferredoxin oxidoreductase inhibitor


Small molecule Approved IMMUNE SYSTEM; OTHER ORAL Hepatitis, Chronic; Cytomegalovirus Infections; HIV Infections; Hepatitis B, Chronic; Virus Diseases DNA polymerase/reverse transcriptase inhibitor


Small molecule Approved OTHER ORAL Hepatitis C; Insulin Resistance; Tuberculosis; Liver Cirrhosis, Biliary; Multiple Sclerosis; Acquired Immunodeficiency Syndrome; Hepatitis B, Chronic; Infections; Severe Acute Respiratory Syndrome; HIV Infections; Virus Diseases Human immunodeficiency virus type 1 reverse transcriptase inhibitor


Small molecule Approved Unknown Unknown Acquired Immunodeficiency Syndrome; HIV Infections; Virus Diseases Unknown


Small molecule Approved IMMUNE SYSTEM; OTHER ORAL Malaria, Vivax; Urethritis; Candidiasis; Helicobacter Infections; Stomach Neoplasms; Vaginitis; Amebiasis; Bacterial Infections; Trichomonas Infections; Vaginosis, Bacterial DNA disrupting agent

Small molecule

Approved

CANCER

INJECTION; INTRAVENOUS

Leukemia, Promyelocytic, Acute; Lymphoma, Follicular; Graft vs Host Disease; Hematologic Diseases; Histiocytosis, Langerhans-Cell; Hodgkin Disease; Leukemia, Biphenotypic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myelomonocytic, Chronic; Lymphoma; Lymphoma, Non-Hodgkin; Multiple Myeloma; Myelodysplastic Syndromes; Osteopetrosis; Leukemia; Leukemia, Myeloid, Acute; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma

DNA inhibitor

Small molecule

Approved

OTHER

ORAL

Breast Carcinoma In Situ; Carcinoma, Merkel Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Chagas Cardiomyopathy; Colorectal Neoplasms; Fatty Liver; Lymphoma, Non-Hodgkin; Melanoma; Metabolic Syndrome; Ovarian Neoplasms; Pancreatic Neoplasms; Severe Acute Respiratory Syndrome; Urinary Bladder Neoplasms; Wounds and Injuries; Aggression; Autistic Disorder; Bipolar Disorder; Breast Neoplasms; Child Development Disorders, Pervasive; Cognitive Dysfunction; Depression, Postpartum; Depressive Disorder; Depressive Disorder, Major; Diabetes Mellitus, Type 1; Dysthymic Disorder; Epilepsy; Glomerulonephritis, IGA; Inflammation; Lichen Planus, Oral; Myositis; Oral Ulcer; Periodontitis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Psychotic Disorders; Renal Insufficiency, Chronic; Sarcopenia; Schizophrenia; Stomatitis; Acne Vulgaris; Alzheimer Disease; Atrial Fibrillation; Attention Deficit Disorder with Hyperactivity; Dry Eye Syndromes; Endocrine System Diseases; Heart Diseases; Heart Failure; HIV Infections; Hypercholesterolemia; Hyperlipidemia, Familial Combined; Hyperlipoproteinemia Type II; Hypertension; Hypertriglyceridemia; Insulin Resistance; Intermittent Claudication; Language Disorders; Lipid Metabolism Disorders; Metabolic Diseases; Myocardial Infarction; Myocardial Ischemia; Non-alcoholic Fatty Liver Disease; Peripheral Arterial Disease; Pyelonephritis; Vascular Diseases; Cardiovascular Diseases; Diabetes Mellitus; Diabetes Mellitus, Type 2; Hypothyroidism

Unknown

Small molecule

Approved

HEMATOLOGY; OTHER

INTRAVENOUS; SUBCUTANEOUS

Acute Kidney Injury; Blastic Plasmacytoid Dendritic Cell Neoplasm; Brain Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Colorectal Neoplasms; Ependymoma; Esophageal Neoplasms; Glioma; Graft vs Host Disease; Head and Neck Neoplasms; Leukemia, Biphenotypic, Acute; Leukemia, Large Granular Lymphocytic; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liposarcoma; Lymphoma, Non-Hodgkin; Mastocytosis, Systemic; Myelodysplastic-Myeloproliferative Diseases; Osteosarcoma; Sarcoma; Tuberculosis; beta-Thalassemia; Breast Neoplasms; Breast Neoplasms, Male; Carcinoma, Non-Small-Cell Lung; Colonic Neoplasms; Hematologic Neoplasms; Hodgkin Disease; Leukemia, Erythroblastic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Lymphoma, Follicular; Melanoma; Multiple Myeloma; Myeloproliferative Disorders; Nasopharyngeal Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Paraganglioma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Myelofibrosis; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Immunoblastic Lymphadenopathy; Leukemia; Leukemia, Myeloid; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, T-Cell, Peripheral; Thrombocytopenia; Anemia, Refractory, with Excess of Blasts; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; Neoplasms

DNA (cytosine-5)-methyltransferase 1 inhibitor


Small molecule Approved Unknown Unknown Carcinoma, Squamous Cell; Cheilitis; Uterine Cervical Dysplasia; Acne Vulgaris; Carcinoma, Basal Cell; Keratosis, Actinic; Skin Aging; Neoplasms Unknown

Small molecule

Approved

CANCER

INTRAVENOUS

Leukemia, Lymphoid; Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Neoplasms, Plasma Cell; Leukemia, Biphenotypic, Acute; Lymphoma; Mycosis Fungoides; Sezary Syndrome; Leukemia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Leukemia-Lymphoma, Adult T-Cell; Neoplasms; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

DNA inhibitor


Small molecule Approved IMMUNE SYSTEM; OTHER ORAL Colorectal Neoplasms; Hepatitis C, Chronic; Hepatitis D; Infections; Liver Failure; Liver Neoplasms; Stomach Neoplasms; Carcinoma, Hepatocellular; Hepatitis B; Hepatitis B, Chronic; Liver Diseases; Virus Diseases DNA polymerase/reverse transcriptase inhibitor


Small molecule Approved OTHER OPHTHALMIC Macular Edema; Miosis; Cataract; Eye Diseases; Inflammation; Ophthalmologic Surgical Procedures; Pain, Postoperative Cyclooxygenase inhibitor