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Total: 1496
Small molecule
Approved
OTHER
ORAL
Osteomyelitis; HIV Infections; Acquired Immunodeficiency Syndrome; Tuberculosis, Multidrug-Resistant; Tuberculosis; Tuberculosis, Pulmonary
70S ribosome inhibitor
Small molecule
Approved
OTHER
INJECTION; ORAL
Postoperative Nausea and Vomiting; Vertigo; Vomiting
Histamine H1 receptor antagonist
Small molecule
Approved
OTHER
OPHTHALMIC; TOPICAL
Corneal Opacity; Dry Eye Syndromes; Acne Vulgaris; Eye Diseases; Hemorrhoids; Inflammation
Glucocorticoid receptor agonist
Small molecule
Approved
OTHER
INJECTION
Unknown
Muscle-type nicotinic acetylcholine receptor antagonist
Small molecule
Approved
OTHER
ORAL
Unknown
Androgen Receptor agonist
Small molecule
Approved
DERMATOLOGY; OTHER
TOPICAL
Dermatitis, Atopic; Eye Diseases; Skin Diseases
Glucocorticoid receptor agonist
Small molecule
Approved
OTHER
ORAL
Anxiety; Anxiety Disorders; Seizures
GABA-A receptor; anion channel positive allosteric modulator
Small molecule
Approved
CARDIOVASCULAR; DIABETES DRUGS & ENDOCRINOLOGY; OTHER
BUCCAL; IMPLANTATION; INJECTION; NASAL; TRANSDERMAL
Cerebral Arterial Diseases; Dyspareunia; Insulin Resistance; Polycystic Ovary Syndrome; Aging; Kallmann Syndrome; Penile Induration; Acquired Immunodeficiency Syndrome; Anorexia Nervosa; Dwarfism; Heart Failure; Hereditary Breast and Ovarian Cancer Syndrome; Menopause; Multiple Sclerosis; Muscular Diseases; Obesity; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcopenia; Spinal Cord Injuries; Testicular Neoplasms; Coronary Disease; Disorders of Sex Development; Erectile Dysfunction; Hip Fractures; Infertility; Metabolic Syndrome; Neoplasms; Renal Insufficiency, Chronic; Sexual Dysfunction, Physiological; Hypogonadism; Klinefelter Syndrome; Orchitis
Androgen Receptor agonist
Small molecule
Approved
OTHER
INJECTION
Psoriasis; Psychotic Disorders
Dopamine D2 receptor antagonist
Small molecule
Approved
OTHER
INTRAOCULAR
Presbyopia; Cataract; Glaucoma; Miosis
Muscarinic acetylcholine receptor M3 agonist
Small molecule
Approved
EMERGENCY MEDICINE; NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER
INJECTION
Neuralgia; Aortic Coarctation; Brain Neoplasms; HIV Infections; Prostatic Neoplasms, Castration-Resistant; Sinusitis; Vasospasm, Intracranial; Abdominal Pain; Appendicitis; Blepharoptosis; Blood Coagulation Disorders; Cleft Palate; Dupuytren Contracture; Fasciitis, Plantar; Femoral Neck Fractures; Headache; Hemorrhage; Hernia, Umbilical; Hip Fractures; Hypospadias; Hypotension; Lacrimal Apparatus Diseases; Low Back Pain; Lung Neoplasms; Mucositis; Osteoarthritis, Hip; Osteoarthritis, Knee; Pregnancy; Pulpitis; Rib Fractures; Rotator Cuff Injuries; Sarcoma; Shoulder Pain; Spinal Stenosis; Ankle Fractures; Breast Neoplasms; Breech Presentation; Carcinoma, Non-Small-Cell Lung; Chronic Pain; Cough; Fractures, Bone; Genital Neoplasms, Female; Hallux Valgus; Hemorrhoids; Hernia, Inguinal; Ileus; Liver Diseases; Migraine Disorders; Neoplasms; Osteoarthritis; Pancreatic Neoplasms; Pancreatitis, Chronic; Peritoneal Neoplasms; Postoperative Complications; Postoperative Nausea and Vomiting; Radiculopathy; Toothache; Urethral Stricture; Wounds and Injuries; Hernia; Pain
Sodium channel protein type IV alpha subunit blocker
Small molecule
Approved
OTHER
INHALATION
Unknown
GABA-A receptor; anion channel positive modulator
Small molecule
Approved
OTHER
INJECTION; ORAL; VAGINAL
Prostatic Neoplasms, Castration-Resistant; Neoplasms
Estrogen receptor alpha agonist
Small molecule
Approved
OTHER
INJECTION; ORAL
Depressive Disorder; Diabetes Mellitus, Type 2; Obesity; Adenoma, Islet Cell; Hyperinsulinism; Hypertension; Hypoglycemia
Potassium channel, inwardly rectifying, subfamily J, member 11 opener
Small molecule
Approved
OTHER
ORAL
Osteomyelitis; Anemia; Astrocytoma; Brain Neoplasms; Glioblastoma; Granulomatosis with Polyangiitis; Kidney Diseases; Leukemia, Biphenotypic, Acute; Neoplasms; Cystic Fibrosis; Dermatitis, Atopic; Diabetes Mellitus, Type 1; Eczema; Epidermolysis Bullosa; Lymphoma, AIDS-Related; Abscess; HIV Infections; Idiopathic Pulmonary Fibrosis; Malaria; Measles; Pneumonia; Pyelonephritis; Sepsis; Staphylococcal Infections; Toxoplasmosis, Ocular; Tuberculosis; Bacterial Infections; Infections; Otitis Media; Pneumonia, Pneumocystis; Urinary Tract Infections
Bacterial dihydrofolate reductase inhibitor
Small molecule
Approved
OTHER
ORAL
Renal Insufficiency, Chronic; Cardiovascular Diseases; Heart Failure; Hypertension; Toxemia
Thiazide-sensitive sodium-chloride cotransporter inhibitor
Small molecule
Approved
OTHER
ORAL
Kidney Diseases; Graves Disease; Hyperlipoproteinemia Type II; Lipid Metabolism Disorders; Multiple Sclerosis; Myocardial Infarction; Myocardial Ischemia; Hypercholesterolemia; Hypothyroidism; Nephrotic Syndrome
Bile acids sequestering agent
Small molecule
Approved
OTHER
BUCCAL; ORAL; SUBLINGUAL
Menopause; Breast Neoplasms; Hypogonadism; Orchitis
Androgen Receptor agonist
Small molecule
Approved
OTHER
ORAL
Rhinitis, Allergic, Seasonal
Histamine H1 receptor antagonist
Protein
Approved
OTHER
INJECTION
Gonadal Disorders; Anovulation; Azoospermia; Breast Neoplasms; Hypogonadism; Infertility; Polycystic Ovary Syndrome; Pregnancy
Luteinizing hormone/Choriogonadotropin receptor agonist
Small molecule
Approved
OTHER
ORAL
Heart Diseases; Substance-Related Disorders; Brain Injuries; Status Epilepticus; Sleep Initiation and Maintenance Disorders
GABA-A receptor; anion channel positive allosteric modulator
Small molecule
Approved
OTHER
ORAL
Osteomyelitis; Astrocytoma; Brain Neoplasms; Glioblastoma; Granulomatosis with Polyangiitis; Kidney Diseases; Leukemia, Biphenotypic, Acute; Neoplasms; Cystic Fibrosis; Dermatitis, Atopic; Diabetes Mellitus, Type 1; Eczema; Lymphoma, AIDS-Related; Abscess; HIV Infections; Idiopathic Pulmonary Fibrosis; Malaria; Measles; Pneumonia; Pyelonephritis; Sepsis; Staphylococcal Infections; Toxoplasmosis, Ocular; Tuberculosis; Bacterial Infections; Infections; Pneumonia, Pneumocystis; Urinary Tract Infections
Bacterial dihydropteroate synthase inhibitor
Small molecule
Approved
OTHER
ORAL
Attention Deficit Disorder with Hyperactivity; Cocaine-Related Disorders; Obesity
Monoamine transporter inhibitor
Small molecule
Approved
IMMUNE SYSTEM; OTHER; PEDIATRICS
ORAL
Diarrhea; Inflammation; Osteomyelitis; Tooth Diseases; Astrocytoma; Brain Neoplasms; Central Serous Chorioretinopathy; Glioblastoma; Obesity; Obesity, Morbid; Postoperative Complications; Asthma; Bacteremia; Chlamydia Infections; Colitis, Ulcerative; Head and Neck Neoplasms; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Mastitis; Periapical Periodontitis; Pneumonia, Bacterial; Pseudomyxoma Peritonei; Tuberculosis; Tuberculosis, Pulmonary; Vaginosis, Bacterial; Abscess; Bronchitis, Chronic; Cholecystitis; Communicable Diseases; Dyspepsia; Endocarditis; Enterobacteriaceae Infections; Fever; Gastritis; Helicobacter Infections; Hemorrhage; Hepatitis, Alcoholic; Low Back Pain; Lymphoma, Non-Hodgkin; Malaria; Neutropenia; Otitis Media, Suppurative; Periodontitis; Pyelonephritis; Severe Acute Respiratory Syndrome; Stomach Ulcer; Bacterial Infections; Duodenal Ulcer; Gonorrhea; Infections; Otitis Media; Pharyngitis; Pneumonia; Respiratory Tract Infections; Sinusitis; Soft Tissue Infections; Tonsillitis; Urinary Tract Infections
Bacterial penicillin-binding protein inhibitor
Small molecule
Approved
OTHER
INJECTION
Unknown
Unknown
Small molecule
Approved
OTHER
INJECTION
Atrophic Vaginitis
Androgen Receptor agonist
Small molecule
Approved
OTHER
ORAL
Glioma; Hookworm Infections; Pruritus; Anemia; Colorectal Neoplasms; Necatoriasis; Helminthiasis
Tubulin inhibitor
Small molecule
Approved
OTHER
ORAL; TRANSDERMAL
Brain Ischemia; Cocaine-Related Disorders; Dermatitis, Atopic; Heroin Dependence; Hypotension, Orthostatic; Orthostatic Intolerance; Anxiety; Brain Injuries; Breast Neoplasms; Child Development Disorders, Pervasive; Diabetic Neuropathies; Low Back Pain; Marijuana Abuse; Opioid-Related Disorders; Stomatitis; Substance-Related Disorders; Cardiovascular Diseases; Delirium; Fecal Incontinence; Hyperemesis Gravidarum; Neonatal Abstinence Syndrome; Pain; Postoperative Complications; Pregnancy; Scoliosis; Stress Disorders, Post-Traumatic; Attention Deficit Disorder with Hyperactivity; Glaucoma; Hypertension; Migraine Disorders; Neoplasms; Neuralgia
Adrenergic receptor alpha-2 agonist
Small molecule
Approved
OTHER
INJECTION; ORAL
Bacterial Infections
Bacterial penicillin-binding protein inhibitor
Small molecule
Approved
OTHER
INTRAVENOUS; ORAL
Ankle Fractures; Alzheimer Disease; Hypotension, Orthostatic; Malaria; Muscular Dystrophy, Duchenne; Osteoarthritis, Knee; Premature Birth; Rhinitis, Allergic, Seasonal; Temporomandibular Joint Disorders; Brachial Plexus Neuritis; Bronchopulmonary Dysplasia; Cognitive Dysfunction; Depressive Disorder, Major; Diabetes Mellitus, Type 1; Emphysema; Enuresis; Epilepsies, Partial; Glioma; Granulomatous Disease, Chronic; Hemorrhage; Hypertension; Muscular Diseases; Pancreatitis; Periodontitis; Pre-Eclampsia; Retinopathy of Prematurity; Sinusitis; Spondylarthropathies; Spondylosis; Stomatitis, Aphthous; Sunburn; Tension-Type Headache; Tooth Diseases; Tuberculosis; Wounds and Injuries; Altitude Sickness; Breast Neoplasms; Burns; Causalgia; Cerebral Palsy; Chronic Pain; Fractures, Bone; HIV Infections; Hypospadias; Infections; Low Back Pain; Multiple Sclerosis; Neck Pain; Peptic Ulcer; Pulpitis; Respiratory Distress Syndrome; Shock, Septic; Sleep Apnea, Obstructive; Sprains and Strains; Vasculitis; Acute Pain; Arthralgia; Arthritis; Arthritis, Juvenile; Arthritis, Rheumatoid; Back Pain; Cardiovascular Diseases; Common Cold; Ductus Arteriosus, Patent; Dysmenorrhea; Fever; Headache; Influenza, Human; Migraine Disorders; Muscle Cramp; Myalgia; Osteoarthritis; Pain; Pharyngitis; Rheumatic Diseases; Toothache; Vaginitis
Cyclooxygenase inhibitor
Small molecule
Approved
OTHER
TOPICAL
Skin Diseases
Glucocorticoid receptor agonist
Small molecule
Approved
OTHER
TOPICAL
Lice Infestations; Ectoparasitic Infestations
GABA-A receptor negative allosteric modulator
Small molecule
Approved
OTHER
INJECTION
Unknown
Unknown
Small molecule
Approved
OTHER
ORAL
Neoplasms; Prostatic Neoplasms, Castration-Resistant; Small Cell Lung Carcinoma; Carcinoma, Squamous Cell; Hypertension; Laryngeal Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Prostatic Neoplasms; Angina, Stable
Unknown
Small molecule
Approved
OTHER
OPHTHALMIC
Urinary Incontinence; Presbyopia; Glaucoma; Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Miosis; Ocular Hypertension; Sjogren's Syndrome; Xerostomia
Muscarinic acetylcholine receptor M1 agonist