Display Options:
Total: 10647
Unknown
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
Unknown
Unknown
Endometritis; Appendicitis; Renal Insufficiency, Chronic; Tuberculosis; Diabetic Foot; Gonorrhea; Infections; Osteomyelitis; Pneumonia; Pyelonephritis; Urinary Tract Infections; Bacterial Infections
Unknown
Small molecule
Approved
Unknown
Unknown
Hypotension, Orthostatic; Lecithin Cholesterol Acyltransferase Deficiency; Memory Disorders; Obesity; Subarachnoid Hemorrhage; Cocaine-Related Disorders; HIV Infections; Psychotic Disorders; Tobacco Use Disorder; Alzheimer Disease; Anxiety; Autistic Disorder; Dementia, Vascular; Depressive Disorder; Lewy Body Disease; Schizophrenia; Dementia
Unknown
Protein
Approved
OTHER
INTRAVENOUS; SUBCUTANEOUS
Acute Kidney Injury; Brain Injuries; Brain Ischemia; Dysgerminoma; Hematologic Neoplasms; Leukemia; Leukemia, Myeloid, Acute; Lymphoma; Breast Neoplasms; Kidney Diseases; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Large B-Cell, Diffuse; Myelodysplastic Syndromes; Myocardial Infarction; Small Cell Lung Carcinoma; Anemia; Neoplasms; Renal Insufficiency, Chronic
Erythropoietin receptor agonist
Small molecule
Approved
Unknown
Unknown
Depressive Disorder, Major; Fatigue Syndrome, Chronic; Idiopathic Pulmonary Fibrosis; Kidney Diseases; Nasopharyngeal Neoplasms; Castleman Disease; Hearing Loss, Sensorineural; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Colitis, Ulcerative; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Infections; Virus Diseases
Unknown
Small molecule
Approved
Unknown
Unknown
Aspergillosis; Candidiasis, Invasive; Wounds and Injuries; Candidemia; Candidiasis; Candidiasis, Oral; Infections; Mycoses
Unknown
Small molecule
Unknown
Unknown
Unknown
Diabetes Mellitus; Fever; Glaucoma; Heart Failure; Mitral Valve Stenosis; Pancreatic Neoplasms; Asthma; Hepatopulmonary Syndrome; Hernias, Diaphragmatic, Congenital; Hypoplastic Left Heart Syndrome; Liver Cirrhosis; Melanoma; Pulmonary Disease, Chronic Obstructive; Diabetes Mellitus, Type 2; Eisenmenger Complex; Heart Septal Defects, Atrial; Idiopathic Pulmonary Fibrosis; Optic Neuropathy, Ischemic; Persistent Fetal Circulation Syndrome; Scleroderma, Systemic; Ulcer; Familial Primary Pulmonary Hypertension; Heart Defects, Congenital; Hypertension; Hypertension, Pulmonary; Pulmonary Arterial Hypertension
Endothelin receptor, ET-A/ET-B antagonist
Small molecule
Approved
CANCER; DIABETES DRUGS & ENDOCRINOLOGY; MUSCULOSKELETAL; OTHER
INJECTION; INTRAVENOUS; IV (INFUSION)
Adenocarcinoma; Anemia, Sickle Cell; Chondrosarcoma; Menopause; Neuroblastoma; beta-Thalassemia; Carcinoma, Hepatocellular; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Renal Cell; Complex Regional Pain Syndromes; Kidney Neoplasms; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Low Back Pain; Macular Degeneration; Mesothelioma; Nasopharyngeal Neoplasms; Osteosarcoma; Primary Myelofibrosis; Progeria; Urogenital Neoplasms; Uterine Cervical Neoplasms; Arthritis, Rheumatoid; Bone Diseases, Metabolic; Bone Neoplasms; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Fractures, Bone; Giant Cell Tumors; Lung Neoplasms; Lymphoma, Non-Hodgkin; Osteoarthritis, Hip; Osteogenesis Imperfecta; Osteonecrosis; Pain; Plasmacytoma; Reflex Sympathetic Dystrophy; Sarcoma; Sarcoma, Ewing; Spinal Cord Injuries; Bone Diseases; Multiple Myeloma; Neoplasm Metastasis; Osteitis Deformans; Osteoporosis; Osteoporosis, Postmenopausal; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant
Farnesyl diphosphate synthase inhibitor
Small molecule
Approved
OTHER
INTRAVENOUS
Breast Neoplasms; Ischemic Stroke; Myocardial Infarction
Diagnostic agent
Oligosaccharide
Unknown
Unknown
Unknown
Renal Insufficiency; Thromboembolism; Venous Thromboembolism; Pulmonary Embolism; Venous Thrombosis
Antithrombin-III activator
Small molecule
Approved
OTHER; UROLOGY AND KIDNEY
ORAL
Aging; Amyotrophic Lateral Sclerosis; Bulbo-Spinal Atrophy, X-Linked; Prostatitis; Severe Acute Respiratory Syndrome; Alopecia; Hypogonadism; Prostatic Neoplasms, Castration-Resistant; Prostatic Hyperplasia; Prostatic Neoplasms
Steroid 5-alpha-reductase inhibitor
Small molecule
Approved
IMMUNE SYSTEM; OTHER
ORAL
Urinary Tract Infections; Bronchitis, Chronic; Infections; Pharyngitis; Tonsillitis
Bacterial penicillin-binding protein inhibitor
Unknown
Unknown
Unknown
Unknown
Pulmonary Embolism; Renal Insufficiency, Chronic; Respiratory Distress Syndrome; Stroke; Hypotension; Sepsis; Shock, Septic; Thrombosis
Coagulation factor VIII inhibitor
Small molecule
Approved
Unknown
Unknown
Hepatitis; Hepatitis B, Chronic; Hepatitis C, Chronic; Hepatitis D; HIV Infections; Liver Cirrhosis, Biliary; Severe Acute Respiratory Syndrome; Virus Diseases
Unknown
Small molecule
Unknown
Unknown
Unknown
Acquired Immunodeficiency Syndrome; Dysmenorrhea; HIV Infections; Prostatic Hyperplasia
Progesterone receptor agonist
Small molecule
Approved
Unknown
Unknown
Pain; Migraine Disorders
Unknown
Small molecule
Approved
OTHER; RESPIRATORY
INHALATION
Lung Neoplasms; Bronchiolitis Obliterans; Hypersensitivity; Respiratory Distress Syndrome; Severe Acute Respiratory Syndrome; Bronchiectasis; Bronchitis; Tobacco Use Disorder; Asthma; Bronchial Spasm; Bronchitis, Chronic; Emphysema; Pulmonary Disease, Chronic Obstructive
Beta-2 adrenergic receptor agonist
Small molecule
Approved
Unknown
Unknown
Arthritis, Juvenile; Breast Neoplasms; Child Development Disorders, Pervasive; Hepatitis B, Chronic; Hypertension, Pulmonary; Lymphoma; Neoplasms; Asthma; Autistic Disorder; Cystic Fibrosis; Dyspepsia; Eosinophilic Esophagitis; Neuralgia; Digestive System Diseases; Esophageal Neoplasms; Esophagitis, Peptic; Gastritis; Gastrointestinal Hemorrhage; Helicobacter Infections; Hemorrhage; Nausea; Osteoarthritis; Pre-Eclampsia; Stomach Ulcer; Ulcer; Gastroesophageal Reflux; Peptic Ulcer
Unknown
Small molecule
Approved
IMMUNE SYSTEM; OTHER
ORAL
Hepatitis C; Hepatitis, Chronic; Insulin Resistance; Lymphoma; Tuberculosis; Communicable Diseases; Hepatitis D; Lipodystrophy; Liver Cirrhosis, Biliary; Acquired Immunodeficiency Syndrome; Severe Acute Respiratory Syndrome; Hepatitis B, Chronic; HIV Infections; Infections; Liver Diseases
Human immunodeficiency virus type 1 reverse transcriptase inhibitor
Small molecule
Approved
Unknown
Unknown
HIV Infections; Metrorrhagia; Pregnancy
Progesterone receptor agonist
Small molecule
Approved
IMMUNE SYSTEM; OTHER; RESPIRATORY
ORAL
Lecithin Cholesterol Acyltransferase Deficiency; Carcinoma, Non-Small-Cell Lung; Common Cold; Conjunctivitis, Allergic; Dermatitis; Dermatitis, Atopic; Eczema; Pruritus; Rhinitis, Allergic, Perennial; Hypersensitivity; Rhinitis, Allergic, Seasonal; Urticaria
Histamine H1 receptor antagonist
Small molecule
Approved
OTHER; PREGNANCY AND GYNECOLOGY
ORAL
Osteoarthritis, Knee; Pancreatitis; Osteoarthritis; Pain; Pharyngitis; Rheumatic Diseases
Cyclooxygenase-2 inhibitor
Small molecule
Approved
Unknown
Unknown
Migraine Disorders
Unknown
Small molecule
Approved
Unknown
Unknown
Acute Lung Injury; Carcinoma, Renal Cell; Colorectal Neoplasms; Desmoplastic Small Round Cell Tumor; Fibrosarcoma; Hematologic Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Pancreatic Neoplasms; Rhinitis, Allergic, Seasonal; Thymoma; Arthritis, Rheumatoid; Breast Neoplasms; Chordoma; Colonic Neoplasms; Fibroma; Fibromatosis, Aggressive; Glioblastoma; Hypereosinophilic Syndrome; Leukemia, Myeloid, Acute; Lung Neoplasms; Malaria, Falciparum; Melanoma; Scleroderma, Systemic; Severe Acute Respiratory Syndrome; Spinal Cord Injuries; Stomach Neoplasms; Thyroid Neoplasms; Tuberculosis; Gastrointestinal Stromal Tumors; Graft vs Host Disease; Hypertension, Pulmonary; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma; Stroke; Neoplasms
Unknown
Protein
Approved
CANCER
UNKNOWN
Brain Neoplasms; Lymphoma, T-Cell, Cutaneous; Medulloblastoma; Neuroblastoma; Osteosarcoma; Adenocarcinoma of Lung; Anemia, Aplastic; Breast Neoplasms, Male; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Colonic Neoplasms; Colorectal Neoplasms; Diabetes Mellitus, Type 1; Fallopian Tube Neoplasms; Head and Neck Neoplasms; Hematologic Neoplasms; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Melanoma; Myelodysplastic Syndromes; Nasopharyngeal Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Retinoblastoma; Small Cell Lung Carcinoma; Stomach Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Wilms Tumor; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Esophageal Neoplasms; Hodgkin Disease; Lung Neoplasms; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Multiple Myeloma; Neoplasms, Germ Cell and Embryonal; Sarcoma; Triple Negative Breast Neoplasms; Uterine Neoplasms; Infections; Neoplasms; Neutropenia
Granulocyte colony stimulating factor receptor agonist
Small molecule
Approved
Unknown
Unknown
Hyperpigmentation; Lentigo; Melanosis
Unknown
Antibody
Unknown
Unknown
Unknown
Mucopolysaccharidoses; Thyroid Neoplasms; Asthma; Colitis; Dupuytren Contracture; Glomerulosclerosis, Focal Segmental; Inflammation; Netherton Syndrome; Osteoarthritis, Knee; Sarcoidosis; Sciatica; Wet Macular Degeneration; Arthritis, Juvenile; Behcet Syndrome; Crohn Disease; Cystitis, Interstitial; Giant Cell Arteritis; Hidradenitis Suppurativa; Inflammatory Bowel Diseases; Osteoarthritis; Pyoderma; Severe Acute Respiratory Syndrome; Uveitis; Arthritis; Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Immune System Diseases; Psoriasis; Spondylitis, Ankylosing
TNF-alpha inhibitor
Small molecule
Approved
Unknown
Unknown
Diabetes Mellitus, Type 1; Parkinson Disease; Amphetamine-Related Disorders; Cocaine-Related Disorders; Orthostatic Intolerance; Tobacco Use Disorder; Alcoholism; Cognitive Dysfunction; Hypotension, Orthostatic; Marijuana Abuse; Opioid-Related Disorders; Phobia, Social; Sleep Apnea, Obstructive; Sleep Apnea Syndromes; Substance-Related Disorders; Tourette Syndrome; Autistic Disorder; Neoplasms; Schizophrenia; Attention Deficit Disorder with Hyperactivity
Unknown
Enzyme
Approved
CANCER
INTRAVENOUS
Burkitt Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Hyperuricemia; Tumor Lysis Syndrome; Gout; Leukemia; Lymphoma
Uric acid oxidative enzyme
Small molecule
Approved
CANCER
INTRAMUSCULAR
Carcinoma, Ductal; Carcinoma, Squamous Cell; Colorectal Neoplasms; Hereditary Breast and Ovarian Cancer Syndrome; Lymphoma; Lymphoma, Non-Hodgkin; Mesothelioma; Small Cell Lung Carcinoma; Urinary Bladder Neoplasms; Carcinoma; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Non-Small-Cell Lung; Endometrial Neoplasms; Fibrous Dysplasia, Polyostotic; Genital Neoplasms, Female; Hypertension, Pulmonary; Lung Neoplasms; Lupus Erythematosus, Systemic; Ovarian Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Sarcoma, Endometrial Stromal; Uterine Neoplasms; Carcinoma, Lobular; Neoplasm Metastasis; Breast Neoplasms; Neoplasms
Estrogen receptor antagonist
Unknown
Approved
Unknown
Unknown
Unknown
Unknown
Small molecule
Approved
OTHER; PEDIATRICS
ORAL
Albinism; Alkaptonuria; Tyrosinemias
4-hydroxyphenylpyruvate dioxygenase inhibitor
Small molecule
Approved
CARDIOVASCULAR; OTHER; RESPIRATORY
INHALATION; INTRAVENOUS; IV (INFUSION); SUBCUTANEOUS
Raynaud Disease; Diabetic Foot; Reperfusion Injury; Scleroderma, Systemic; Hernias, Diaphragmatic, Congenital; Ischemia; Peripheral Vascular Diseases; Persistent Fetal Circulation Syndrome; Pulmonary Disease, Chronic Obstructive; Respiratory Distress Syndrome; Familial Primary Pulmonary Hypertension; Idiopathic Pulmonary Fibrosis; Hypertension, Pulmonary; Pulmonary Arterial Hypertension; Thrombosis
Prostanoid IP receptor agonist
Small molecule
Approved
IMMUNE SYSTEM; OTHER
INJECTION; INTRAVENOUS; IV (INFUSION); ORAL
Asthma; Graft vs Host Disease; Hematologic Neoplasms; HIV Infections; Keratitis; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasms; Neutropenia; Aspergillosis, Allergic Bronchopulmonary; Myelodysplastic Syndromes; Candidiasis, Invasive; Leukemia; Leukemia, Myeloid, Acute; Mycoses; Neuroaspergillosis; Aspergillosis; Candidemia; Candidiasis; Fusariosis; Infections
Cytochrome P450 51 inhibitor
Small molecule
Approved
IMMUNE SYSTEM; OTHER; PEDIATRICS
ORAL
HIV Infections; Bronchiolitis; Crohn Disease; Gastroenteritis; Hepatitis B, Chronic; Hepatitis C; Hepatitis C, Chronic; Malnutrition; Periodontitis; Tuberculosis; Amebiasis; Brain Diseases; Clostridium Infections; Cryptosporidiosis; Dyspepsia; Enterocolitis, Pseudomembranous; Helicobacter Infections; Influenza, Human; Peritonitis; Respiratory Tract Diseases; Severe Acute Respiratory Syndrome; Diarrhea
Pyruvate:ferredoxin oxidoreductase inhibitor