DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 10647


Enzyme Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER; UROLOGY AND KIDNEY INTRAVENOUS Fabry Disease Globotriosylceramide hydrolytic enzyme


Small molecule Approved OTHER TOPICAL Candidiasis, Vulvovaginal; Tinea Pedis Cytochrome P450 51 inhibitor


Enzyme Approved RESPIRATORY UNKNOWN Glycogen Storage Disease Type III; Mucopolysaccharidoses; Mucopolysaccharidosis I Dermatan sulfate hydrolytic enzyme


Small molecule Approved OTHER ORAL Diarrhea; Neuronal Ceroid-Lipofuscinoses; Cystic Fibrosis; HIV Infections; Spastic Paraplegia, Hereditary; Gangliosidoses, GM2; Glycogen Storage Disease; Niemann-Pick Disease, Type C; Sandhoff Disease; Gaucher Disease; Glycogen Storage Disease Type II; Niemann-Pick Diseases Ceramide glucosyltransferase inhibitor


Small molecule Approved CANCER; GASTROINTESTINAL; OTHER INTRAVENOUS; ORAL Glioblastoma; Heroin Dependence; HIV Infections; Opioid-Related Disorders; Alcoholism; Cocaine-Related Disorders; Gastroparesis; Leukemia, Myeloid, Acute; Marijuana Abuse; Pain; Pruritus; Severe Acute Respiratory Syndrome; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Depressive Disorder, Major; Dysmenorrhea; Multiple Myeloma; Neoplasms, Germ Cell and Embryonal; Nausea; Neoplasms; Postoperative Nausea and Vomiting; Vomiting Neurokinin 1 receptor antagonist

Small molecule

Approved

CANCER; GASTROINTESTINAL; OTHER

INTRAVENOUS; ORAL

Glioblastoma; Heroin Dependence; HIV Infections; Opioid-Related Disorders; Alcoholism; Cocaine-Related Disorders; Gastroparesis; Leukemia, Myeloid, Acute; Marijuana Abuse; Pain; Pruritus; Severe Acute Respiratory Syndrome; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Depressive Disorder, Major; Dysmenorrhea; Multiple Myeloma; Neoplasms, Germ Cell and Embryonal; Nausea; Neoplasms; Postoperative Nausea and Vomiting; Vomiting

Neurokinin 1 receptor antagonist


Small molecule Approved Unknown Unknown Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Eye Manifestations; Hypersensitivity Unknown


Small molecule Approved Unknown Unknown Melanoma; Vomiting; Brain Neoplasms; Breast Neoplasms; Glioma; Multiple Myeloma; Stomach Neoplasms; Neoplasms; Postoperative Nausea and Vomiting; Strabismus; Nausea Unknown


Protein Approved Unknown Unknown Thrombosis; Venous Thrombosis Thrombin inhibitor


Small molecule Approved Unknown Unknown Reperfusion Injury; Cystic Fibrosis; Prostatic Hyperplasia; Raynaud Disease; Tinnitus; Urinary Bladder, Overactive; Hypertension, Pulmonary; Erectile Dysfunction Unknown


Small molecule Approved CANCER INJECTION; INTRAVENOUS; SUBCUTANEOUS; UNKNOWN Anemia, Refractory, with Excess of Blasts; Astrocytoma; Burkitt Lymphoma; Carcinoma, Medullary; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Fallopian Tube Neoplasms; Immunoblastic Lymphadenopathy; Leukemia, Lymphoid; Leukemia-Lymphoma, Adult T-Cell; Lymphoma, AIDS-Related; Lymphoma, Large-Cell, Anaplastic; Muscular Dystrophies; Mycosis Fungoides; Myeloproliferative Disorders; Neuroblastoma; Oligodendroglioma; Peritoneal Neoplasms; Sezary Syndrome; Smoldering Multiple Myeloma; Uremia; Adenocarcinoma, Follicular; Adenocarcinoma of Lung; Anemia, Hemolytic, Autoimmune; Autoimmune Diseases of the Nervous System; Breast Neoplasms; Bronchiolitis Obliterans; Bronchiolitis Obliterans Syndrome; Carcinoma, Adenoid Cystic; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Castleman Disease; Central Nervous System Neoplasms; Colorectal Neoplasms; Esophageal Neoplasms; Glioblastoma; Gliosarcoma; Graft vs Host Disease; Head and Neck Neoplasms; Hematologic Neoplasms; Hodgkin Disease; Immune System Diseases; Kidney Neoplasms; Leukemia, Biphenotypic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Plasma Cell; Leukemia, Promyelocytic, Acute; Liver Neoplasms; Lung Neoplasms; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, T-Cell, Peripheral; Lymphoproliferative Disorders; Melanoma; Mesothelioma; Myelodysplastic Syndromes; Nasopharyngeal Neoplasms; Neoplasms, Plasma Cell; Neuromyelitis Optica; Ovarian Neoplasms; Pancreatic Neoplasms; Paraganglioma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Red-Cell Aplasia, Pure; Sarcoma; Stomach Neoplasms; Thyroid Neoplasms; Ureteral Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Uveal Melanoma; Amyloidosis; Amyloidosis, Familial; Cholangiocarcinoma; Immunoglobulin Light-chain Amyloidosis; Leukemia; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Multiple Myeloma; Plasmacytoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Purpura, Thrombocytopenic, Idiopathic; Renal Insufficiency, Chronic; Sarcoma, Myeloid; Waldenstrom Macroglobulinemia; Neoplasms 26S proteasome inhibitor

Small molecule

Approved

CANCER

INJECTION; INTRAVENOUS; SUBCUTANEOUS; UNKNOWN

Anemia, Refractory, with Excess of Blasts; Astrocytoma; Burkitt Lymphoma; Carcinoma, Medullary; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Fallopian Tube Neoplasms; Immunoblastic Lymphadenopathy; Leukemia, Lymphoid; Leukemia-Lymphoma, Adult T-Cell; Lymphoma, AIDS-Related; Lymphoma, Large-Cell, Anaplastic; Muscular Dystrophies; Mycosis Fungoides; Myeloproliferative Disorders; Neuroblastoma; Oligodendroglioma; Peritoneal Neoplasms; Sezary Syndrome; Smoldering Multiple Myeloma; Uremia; Adenocarcinoma, Follicular; Adenocarcinoma of Lung; Anemia, Hemolytic, Autoimmune; Autoimmune Diseases of the Nervous System; Breast Neoplasms; Bronchiolitis Obliterans; Bronchiolitis Obliterans Syndrome; Carcinoma, Adenoid Cystic; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Castleman Disease; Central Nervous System Neoplasms; Colorectal Neoplasms; Esophageal Neoplasms; Glioblastoma; Gliosarcoma; Graft vs Host Disease; Head and Neck Neoplasms; Hematologic Neoplasms; Hodgkin Disease; Immune System Diseases; Kidney Neoplasms; Leukemia, Biphenotypic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Plasma Cell; Leukemia, Promyelocytic, Acute; Liver Neoplasms; Lung Neoplasms; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, T-Cell, Peripheral; Lymphoproliferative Disorders; Melanoma; Mesothelioma; Myelodysplastic Syndromes; Nasopharyngeal Neoplasms; Neoplasms, Plasma Cell; Neuromyelitis Optica; Ovarian Neoplasms; Pancreatic Neoplasms; Paraganglioma; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Red-Cell Aplasia, Pure; Sarcoma; Stomach Neoplasms; Thyroid Neoplasms; Ureteral Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Uveal Melanoma; Amyloidosis; Amyloidosis, Familial; Cholangiocarcinoma; Immunoglobulin Light-chain Amyloidosis; Leukemia; Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Multiple Myeloma; Plasmacytoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Purpura, Thrombocytopenic, Idiopathic; Renal Insufficiency, Chronic; Sarcoma, Myeloid; Waldenstrom Macroglobulinemia; Neoplasms

26S proteasome inhibitor


Small molecule Approved Unknown Unknown Hypersensitivity Unknown


Small molecule Approved OTHER ORAL Angioedema; Conjunctivitis, Allergic; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Rhinitis, Vasomotor; Urticaria Histamine H1 receptor antagonist


Antibody Approved Unknown Unknown Arthritis, Psoriatic; Hidradenitis Suppurativa; Immune System Diseases; Kidney Failure, Chronic; Macular Degeneration; Alopecia; Arthritis, Rheumatoid; Diabetes Mellitus, Type 1; Sjogren's Syndrome; Psoriasis Integrin alpha-L/beta-2 (LFA-1) inhibitor


Small molecule Approved OTHER ORAL Unknown Voltage-gated L-type calcium channel blocker


Small molecule Approved Unknown Unknown Abdominal Pain; Bone Diseases; Bone Neoplasms; Breast Neoplasms; Hematologic Neoplasms; Multiple Myeloma; Neoplasm Metastasis; Osteonecrosis; Osteoporosis; Osteoporosis, Postmenopausal; Pain Unknown


Protein Approved CANCER INTRAMUSCULAR Prostatic Neoplasms, Castration-Resistant; Neoplasms Gonadotropin-releasing hormone receptor antagonist


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; RESPIRATORY ORAL Astrocytoma; Depressive Disorder, Major; Glioblastoma; Head and Neck Neoplasms; Heart Failure; Muscular Dystrophies; Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cushing Syndrome; Dementia, Vascular; Diabetes Mellitus, Type 2; Eisenmenger Complex; Essential Hypertension; Gastroparesis; Hypertension; Multiple Myeloma; Obesity; Pancreatic Neoplasms; Priapism; Scleroderma, Systemic; Sexual Dysfunction, Physiological; Stroke; Glucose Intolerance; Heart Defects, Congenital; Insulin Resistance; Lung Diseases, Interstitial; Muscular Dystrophy, Duchenne; Premature Ejaculation; Raynaud Disease; Transposition of Great Vessels; Erectile Dysfunction; Hypertension, Pulmonary; Prostatic Hyperplasia; Pulmonary Arterial Hypertension Phosphodiesterase 5A inhibitor

Small molecule

Approved

NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER; RESPIRATORY

ORAL

Astrocytoma; Depressive Disorder, Major; Glioblastoma; Head and Neck Neoplasms; Heart Failure; Muscular Dystrophies; Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cushing Syndrome; Dementia, Vascular; Diabetes Mellitus, Type 2; Eisenmenger Complex; Essential Hypertension; Gastroparesis; Hypertension; Multiple Myeloma; Obesity; Pancreatic Neoplasms; Priapism; Scleroderma, Systemic; Sexual Dysfunction, Physiological; Stroke; Glucose Intolerance; Heart Defects, Congenital; Insulin Resistance; Lung Diseases, Interstitial; Muscular Dystrophy, Duchenne; Premature Ejaculation; Raynaud Disease; Transposition of Great Vessels; Erectile Dysfunction; Hypertension, Pulmonary; Prostatic Hyperplasia; Pulmonary Arterial Hypertension

Phosphodiesterase 5A inhibitor


Small molecule Approved Unknown Unknown Hypoglycemia; Rhinoscleroma; Helicobacter Infections; Peritonitis; Bacterial Infections Unknown


Protein Approved IMMUNE SYSTEM SUBCUTANEOUS Acquired Immunodeficiency Syndrome; HIV Infections; Virus Diseases Transmembrane glycoprotein gp41 inhibitor


Antibody Approved RESPIRATORY UNKNOWN Colonic Neoplasms; Dermatitis, Atopic; Drug Hypersensitivity; Job Syndrome; Lupus Erythematosus, Systemic; Bronchitis; Chronic Inducible Urticaria; Cold Urticaria; Eosinophilic Esophagitis; Food Hypersensitivity; Gastroenteritis; Hypersensitivity; Immune System Diseases; Milk Hypersensitivity; Nephritis, Interstitial; Pemphigoid, Bullous; Pulmonary Disease, Chronic Obstructive; Severe Acute Respiratory Syndrome; Angioedema; Chronic Urticaria; Cystitis, Interstitial; Peanut Hypersensitivity; Rhinitis, Allergic, Seasonal; Sinusitis; Asthma; Lung Diseases, Obstructive; Rhinitis; Urticaria Ig epsilon chain C region inhibitor

Antibody

Approved

RESPIRATORY

UNKNOWN

Colonic Neoplasms; Dermatitis, Atopic; Drug Hypersensitivity; Job Syndrome; Lupus Erythematosus, Systemic; Bronchitis; Chronic Inducible Urticaria; Cold Urticaria; Eosinophilic Esophagitis; Food Hypersensitivity; Gastroenteritis; Hypersensitivity; Immune System Diseases; Milk Hypersensitivity; Nephritis, Interstitial; Pemphigoid, Bullous; Pulmonary Disease, Chronic Obstructive; Severe Acute Respiratory Syndrome; Angioedema; Chronic Urticaria; Cystitis, Interstitial; Peanut Hypersensitivity; Rhinitis, Allergic, Seasonal; Sinusitis; Asthma; Lung Diseases, Obstructive; Rhinitis; Urticaria

Ig epsilon chain C region inhibitor


Small molecule Approved Unknown Unknown Constipation Unknown


Protein Approved Unknown Unknown Down Syndrome; Alzheimer Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Myocardial Infarction; Diabetes Mellitus Insulin receptor agonist


Small molecule Approved IMMUNE SYSTEM; OTHER; RESPIRATORY ORAL Asthma; Maxillary Sinusitis; Otitis Media; Otitis Media, Suppurative; Scrub Typhus; Bacterial Infections; Bronchitis, Chronic; Community-Acquired Infections; Infections; Pharyngitis; Pneumonia; Pneumonia, Bacterial; Sinusitis; Tonsillitis Bacterial 70S ribosome inhibitor


Small molecule Approved Unknown Unknown Urinary Incontinence, Urge; Prostatic Hyperplasia; Urinary Bladder, Overactive; Polyuria; Urinary Incontinence Unknown


Protein Approved OTHER INTRAVENOUS Obsessive-Compulsive Disorder; Autistic Disorder Secretin receptor agonist


Small molecule Approved Unknown Unknown Bronchitis, Chronic; Renal Insufficiency; Spinal Cord Injuries; Asthma; Pulmonary Disease, Chronic Obstructive Unknown


Small molecule Approved OTHER INTRAVENOUS Breast Neoplasms; Hernias, Diaphragmatic, Congenital Diagnostic agent


Small molecule Approved IMMUNE SYSTEM; OTHER ORAL Malaria, Vivax; Urethritis; Candidiasis; Helicobacter Infections; Stomach Neoplasms; Vaginitis; Amebiasis; Bacterial Infections; Trichomonas Infections; Vaginosis, Bacterial DNA disrupting agent


Small molecule Approved Unknown Unknown Kidney Diseases; Hyperphosphatemia; Kidney Failure, Chronic Phosphate sequestering agent

Small molecule

Approved

Unknown

Adenocarcinoma of Lung; Astrocytoma; Brain Neoplasms; Carcinoma, Renal Cell; Central Nervous System Neoplasms; Colonic Neoplasms; Glioma; Hemorrhagic Fever, Ebola; Hepatitis C, Chronic; Melanoma; Multiple Myeloma; Oligodendroglioma; Pharyngeal Neoplasms; Rectal Neoplasms; Adenocarcinoma, Bronchiolo-Alveolar; Adenomatous Polyposis Coli; Breast Neoplasms; Carcinoma; Diffuse Intrinsic Pontine Glioma; Digestive System Diseases; Ependymoma; Esophageal Neoplasms; Fallopian Tube Neoplasms; Glioblastoma; Gliosarcoma; Hematologic Neoplasms; Leukemia; Leukemia, Myeloid, Acute; Liver Neoplasms; Mesothelioma; Myelodysplastic Syndromes; Nasopharyngeal Neoplasms; Neoplasms, Germ Cell and Embryonal; Neuroendocrine Tumors; Ovarian Neoplasms; Polycythemia Vera; Prostatic Neoplasms, Castration-Resistant; Psoriasis; Skin Neoplasms; Thymoma; Urinary Bladder Neoplasms; Biliary Tract Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colorectal Neoplasms; Head and Neck Neoplasms; Lung Neoplasms; Mouth Neoplasms; Neoplasm Metastasis; Neoplasms; Pancreatic Neoplasms

Unknown


Small molecule Approved Unknown Unknown Atrophy; Menopause Estrogen receptor agonist

Small molecule

Approved

HEMATOLOGY; OTHER

INTRAVENOUS; SUBCUTANEOUS

Acute Kidney Injury; Blastic Plasmacytoid Dendritic Cell Neoplasm; Brain Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Colorectal Neoplasms; Ependymoma; Esophageal Neoplasms; Glioma; Graft vs Host Disease; Head and Neck Neoplasms; Leukemia, Biphenotypic, Acute; Leukemia, Large Granular Lymphocytic; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Liposarcoma; Lymphoma, Non-Hodgkin; Mastocytosis, Systemic; Myelodysplastic-Myeloproliferative Diseases; Osteosarcoma; Sarcoma; Tuberculosis; beta-Thalassemia; Breast Neoplasms; Breast Neoplasms, Male; Carcinoma, Non-Small-Cell Lung; Colonic Neoplasms; Hematologic Neoplasms; Hodgkin Disease; Leukemia, Erythroblastic, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Lymphoma, Follicular; Melanoma; Multiple Myeloma; Myeloproliferative Disorders; Nasopharyngeal Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Paraganglioma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Myelofibrosis; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Immunoblastic Lymphadenopathy; Leukemia; Leukemia, Myeloid; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, T-Cell, Peripheral; Thrombocytopenia; Anemia, Refractory, with Excess of Blasts; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; Neoplasms

DNA (cytosine-5)-methyltransferase 1 inhibitor


Small molecule Approved NEUROLOGY DRUGS & NERVOUS SYSTEM; OTHER ORAL Marijuana Abuse; Anxiety Disorders; Sleep Apnea, Obstructive; Sleep Initiation and Maintenance Disorders GABA-A receptor; anion channel positive allosteric modulator


Unknown Approved Unknown Unknown Unknown Unknown


Small molecule Approved Unknown Unknown Urinary Bladder, Overactive; Polyuria; Urinary Incontinence Unknown