DrugMapper


Display Options: Drug type Therapeutic Area Route of administration Mechanism of Action Indication Status		Total: 1496


Small molecule Approved CARDIOVASCULAR; OTHER ORAL Cerebrovascular Disorders; Intracranial Aneurysm; Schizophrenia; Cocaine-Related Disorders; Infertility; Muscle Cramp; Neuroma, Acoustic; Stroke; Poisoning; Subarachnoid Hemorrhage; Cardiovascular Diseases Mineralocorticoid receptor antagonist


Small molecule Approved OTHER INJECTION Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Neoplasm Metastasis; Neoplasms, Plasma Cell; Breast Neoplasms; Burkitt Lymphoma; Leukemia, Myeloid, Acute; Lymphoma, AIDS-Related; Lymphoma, B-Cell; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Nasopharyngeal Neoplasms; Pancreatic Neoplasms; Penile Neoplasms; Peritoneal Neoplasms; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Urethral Neoplasms; Urinary Bladder Neoplasms; Uterine Neoplasms; Wilms Tumor; Carcinoma; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Dermatofibrosarcoma; Endometrial Neoplasms; Fallopian Tube Neoplasms; Fibrosarcoma; Hemangiosarcoma; Histiocytoma; Hodgkin Disease; Kidney Neoplasms; Leiomyosarcoma; Leukemia; Leukemia, Biphenotypic, Acute; Liposarcoma; Lung Neoplasms; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Mediastinal Neoplasms; Neoplasms, Germ Cell and Embryonal; Neurilemmoma; Neuroblastoma; Osteosarcoma; Ovarian Neoplasms; Pheochromocytoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Retroviridae Infections; Rhabdomyosarcoma; Sarcoma; Sarcoma, Alveolar Soft Part; Sarcoma, Ewing; Sarcoma, Synovial; Small Cell Lung Carcinoma; Teratoma; Uterine Cervical Neoplasms; Neoplasms; Testicular Neoplasms DNA inhibitor

Small molecule

Approved

OTHER

INJECTION

Multiple Myeloma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Neoplasm Metastasis; Neoplasms, Plasma Cell; Breast Neoplasms; Burkitt Lymphoma; Leukemia, Myeloid, Acute; Lymphoma, AIDS-Related; Lymphoma, B-Cell; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Nasopharyngeal Neoplasms; Pancreatic Neoplasms; Penile Neoplasms; Peritoneal Neoplasms; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Urethral Neoplasms; Urinary Bladder Neoplasms; Uterine Neoplasms; Wilms Tumor; Carcinoma; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Dermatofibrosarcoma; Endometrial Neoplasms; Fallopian Tube Neoplasms; Fibrosarcoma; Hemangiosarcoma; Histiocytoma; Hodgkin Disease; Kidney Neoplasms; Leiomyosarcoma; Leukemia; Leukemia, Biphenotypic, Acute; Liposarcoma; Lung Neoplasms; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Mediastinal Neoplasms; Neoplasms, Germ Cell and Embryonal; Neurilemmoma; Neuroblastoma; Osteosarcoma; Ovarian Neoplasms; Pheochromocytoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Retroviridae Infections; Rhabdomyosarcoma; Sarcoma; Sarcoma, Alveolar Soft Part; Sarcoma, Ewing; Sarcoma, Synovial; Small Cell Lung Carcinoma; Teratoma; Uterine Cervical Neoplasms; Neoplasms; Testicular Neoplasms

DNA inhibitor


Small molecule Approved OTHER INJECTION Neoplasms Diagnostic agent


Small molecule Approved OTHER INJECTION Esophageal and Gastric Varices Calcium chelating agent


Small molecule Approved OTHER ORAL Chemical and Drug Induced Liver Injury; Cystinuria; Subarachnoid Hemorrhage Reducing agent


Small molecule Approved OTHER INJECTION Cicatrix; Cardiomyopathy, Dilated; Hypertension Angiotensin-converting enzyme inhibitor


Small molecule Approved OTHER ORAL Aging; Alcoholism; Depressive Disorder; Fractures, Bone; Neoplasms; Pancreatitis; Periodontitis; Bile Duct Diseases; Carcinoma; Carcinoma, Basal Cell; Mastodynia; Pulmonary Embolism; Wounds and Injuries; Infertility; Osteoarthritis, Hip; Osteoarthritis, Knee; Renal Colic; Spondylitis, Ankylosing; Stomach Ulcer; Toothache; Acute Pain; Arthralgia; Arthritis, Rheumatoid; Cataract; Dysmenorrhea; Eye Diseases; Inflammation; Keratosis, Actinic; Migraine Disorders; Myalgia; Osteoarthritis; Rheumatic Diseases; Sprains and Strains Cyclooxygenase inhibitor

Small molecule

Approved

OTHER

ORAL

Aging; Alcoholism; Depressive Disorder; Fractures, Bone; Neoplasms; Pancreatitis; Periodontitis; Bile Duct Diseases; Carcinoma; Carcinoma, Basal Cell; Mastodynia; Pulmonary Embolism; Wounds and Injuries; Infertility; Osteoarthritis, Hip; Osteoarthritis, Knee; Renal Colic; Spondylitis, Ankylosing; Stomach Ulcer; Toothache; Acute Pain; Arthralgia; Arthritis, Rheumatoid; Cataract; Dysmenorrhea; Eye Diseases; Inflammation; Keratosis, Actinic; Migraine Disorders; Myalgia; Osteoarthritis; Rheumatic Diseases; Sprains and Strains

Cyclooxygenase inhibitor


Small molecule Approved GASTROINTESTINAL; OTHER ORAL Alzheimer Disease; Anemia; Anemia, Sickle Cell; Arthritis, Rheumatoid; Carcinoma, Medullary; Central Serous Chorioretinopathy; Child Development Disorders, Pervasive; Chronic Pain; Clostridium Infections; Colitis, Ulcerative; Communicable Diseases; Crohn Disease; Dermatitis, Atopic; Diabetes Mellitus; Diabetes Mellitus, Type 2; Erectile Dysfunction; Glaucoma; Hepatitis B, Chronic; Hepatitis C; Hepatitis C, Chronic; HIV Infections; Laryngomalacia; Melanoma; Mitochondrial Diseases; Muscular Atrophy, Spinal; Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Psoriasis; Pulmonary Disease, Chronic Obstructive; Breast Neoplasms; Carcinoma, Squamous Cell; Colorectal Neoplasms; Gastrinoma; Gastritis; Granuloma; Head and Neck Neoplasms; Idiopathic Pulmonary Fibrosis; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Prostatic Neoplasms, Castration-Resistant; Squamous Cell Carcinoma of Head and Neck; Squamous Intraepithelial Lesions; Ulcer; Zollinger-Ellison Syndrome; Barrett Esophagus; Cough; Cysticercosis; Diabetes Mellitus, Type 1; Dyspepsia; Esophagitis, Peptic; Exocrine Pancreatic Insufficiency; Gastrointestinal Hemorrhage; Helicobacter Infections; Hemorrhage; Multiple Sclerosis, Relapsing-Remitting; Osteoarthritis; Pain; Peripheral Nervous System Diseases; Spondylitis, Ankylosing; Stomach Neoplasms; Wounds and Injuries; Duodenal Ulcer; Esophagitis; Gastroesophageal Reflux; Heartburn; Infections; Peptic Ulcer; Stomach Ulcer Potassium-transporting ATPase inhibitor

Small molecule

Approved

GASTROINTESTINAL; OTHER

ORAL

Alzheimer Disease; Anemia; Anemia, Sickle Cell; Arthritis, Rheumatoid; Carcinoma, Medullary; Central Serous Chorioretinopathy; Child Development Disorders, Pervasive; Chronic Pain; Clostridium Infections; Colitis, Ulcerative; Communicable Diseases; Crohn Disease; Dermatitis, Atopic; Diabetes Mellitus; Diabetes Mellitus, Type 2; Erectile Dysfunction; Glaucoma; Hepatitis B, Chronic; Hepatitis C; Hepatitis C, Chronic; HIV Infections; Laryngomalacia; Melanoma; Mitochondrial Diseases; Muscular Atrophy, Spinal; Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Psoriasis; Pulmonary Disease, Chronic Obstructive; Breast Neoplasms; Carcinoma, Squamous Cell; Colorectal Neoplasms; Gastrinoma; Gastritis; Granuloma; Head and Neck Neoplasms; Idiopathic Pulmonary Fibrosis; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Prostatic Neoplasms, Castration-Resistant; Squamous Cell Carcinoma of Head and Neck; Squamous Intraepithelial Lesions; Ulcer; Zollinger-Ellison Syndrome; Barrett Esophagus; Cough; Cysticercosis; Diabetes Mellitus, Type 1; Dyspepsia; Esophagitis, Peptic; Exocrine Pancreatic Insufficiency; Gastrointestinal Hemorrhage; Helicobacter Infections; Hemorrhage; Multiple Sclerosis, Relapsing-Remitting; Osteoarthritis; Pain; Peripheral Nervous System Diseases; Spondylitis, Ankylosing; Stomach Neoplasms; Wounds and Injuries; Duodenal Ulcer; Esophagitis; Gastroesophageal Reflux; Heartburn; Infections; Peptic Ulcer; Stomach Ulcer

Potassium-transporting ATPase inhibitor


Small molecule Approved OTHER INJECTION Amnesia; Colorectal Neoplasms; Depressive Disorder; Depressive Disorder, Major; Inflammation; Neural Tube Defects; Osteonecrosis; Premature Birth; Psychomotor Agitation; Renal Insufficiency; Renal Insufficiency, Chronic; Scoliosis; Sepsis; Shock; Sleep Initiation and Maintenance Disorders; Spinal Stenosis; Coronary Disease; Depressive Disorder, Treatment-Resistant; Hypotension; Intestinal Polyps; Leukemia; Lung Neoplasms; Migraine Disorders; Obesity, Morbid; Postoperative Nausea and Vomiting; Pulmonary Disease, Chronic Obstructive; Sleep Apnea, Obstructive; Strabismus; Tonsillitis; Wounds and Injuries; Adenomatous Polyposis Coli; Atrial Fibrillation; Back Pain; Brain Injuries; Breast Neoplasms; Cerebral Arterial Diseases; Delirium; Esophageal Neoplasms; Genital Neoplasms, Male; Heart Diseases; Hypertension; Intracranial Aneurysm; Liver Cirrhosis; Neoplasms; Obesity; Pain; Pancreatic Neoplasms; Pruritus; Reperfusion Injury; Respiratory Distress Syndrome; Respiratory Distress Syndrome, Newborn; Respiratory Insufficiency; Severe Acute Respiratory Syndrome; Shock, Septic; Status Epilepticus; Stroke; Subarachnoid Hemorrhage GABA-A receptor; anion channel positive allosteric modulator

Small molecule

Approved

OTHER

INJECTION

Amnesia; Colorectal Neoplasms; Depressive Disorder; Depressive Disorder, Major; Inflammation; Neural Tube Defects; Osteonecrosis; Premature Birth; Psychomotor Agitation; Renal Insufficiency; Renal Insufficiency, Chronic; Scoliosis; Sepsis; Shock; Sleep Initiation and Maintenance Disorders; Spinal Stenosis; Coronary Disease; Depressive Disorder, Treatment-Resistant; Hypotension; Intestinal Polyps; Leukemia; Lung Neoplasms; Migraine Disorders; Obesity, Morbid; Postoperative Nausea and Vomiting; Pulmonary Disease, Chronic Obstructive; Sleep Apnea, Obstructive; Strabismus; Tonsillitis; Wounds and Injuries; Adenomatous Polyposis Coli; Atrial Fibrillation; Back Pain; Brain Injuries; Breast Neoplasms; Cerebral Arterial Diseases; Delirium; Esophageal Neoplasms; Genital Neoplasms, Male; Heart Diseases; Hypertension; Intracranial Aneurysm; Liver Cirrhosis; Neoplasms; Obesity; Pain; Pancreatic Neoplasms; Pruritus; Reperfusion Injury; Respiratory Distress Syndrome; Respiratory Distress Syndrome, Newborn; Respiratory Insufficiency; Severe Acute Respiratory Syndrome; Shock, Septic; Status Epilepticus; Stroke; Subarachnoid Hemorrhage

GABA-A receptor; anion channel positive allosteric modulator


Unknown Approved OTHER INTRATHECAL Unknown Unknown


Small molecule Approved OTHER ORAL Anxiety; Bipolar Disorder; Dementia; Depressive Disorder; Developmental Disabilities; Intellectual Disability; Psychotic Disorders; Schizophrenia Dopamine D2 receptor antagonist


Protein Approved OTHER UNKNOWN HIV Infections; Severe Acute Respiratory Syndrome Interferon alpha/beta receptor agonist


Small molecule Approved OTHER ORAL Hypertension Sulfonylurea receptor 2, Kir6.2 opener


Small molecule Approved EYE; OTHER IMPLANTATION; OPHTHALMIC; ORAL Central Nervous System Neoplasms; Kidney Diseases; Melanoma; Mesothelioma; Neuroblastoma; Carcinoma, Hepatocellular; Diabetes Mellitus, Type 1; Fallopian Tube Neoplasms; Glioblastoma; Graft vs Host Disease; Lymphoma; Ovarian Neoplasms; Peritoneal Neoplasms; Conjunctivitis; Cytomegalovirus Infections; Infections; Cytomegalovirus Retinitis; Eye Infections; HIV Infections; Virus Diseases Human herpesvirus 1 DNA polymerase inhibitor

Small molecule

Approved

EYE; OTHER

IMPLANTATION; OPHTHALMIC; ORAL

Central Nervous System Neoplasms; Kidney Diseases; Melanoma; Mesothelioma; Neuroblastoma; Carcinoma, Hepatocellular; Diabetes Mellitus, Type 1; Fallopian Tube Neoplasms; Glioblastoma; Graft vs Host Disease; Lymphoma; Ovarian Neoplasms; Peritoneal Neoplasms; Conjunctivitis; Cytomegalovirus Infections; Infections; Cytomegalovirus Retinitis; Eye Infections; HIV Infections; Virus Diseases

Human herpesvirus 1 DNA polymerase inhibitor


Small molecule Approved OTHER; UROLOGY AND KIDNEY ORAL Ovarian Neoplasms; Polycystic Ovary Syndrome; Prostatic Neoplasms, Castration-Resistant; Carcinoma; Neoplasms; Prostatic Neoplasms Androgen Receptor antagonist


Small molecule Approved OTHER INJECTION; INTRAVENOUS Inflammation; Ischemia; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Cardiomyopathies; Coronary Disease; Pain; Respiratory Distress Syndrome; ST Elevation Myocardial Infarction; Takotsubo Cardiomyopathy; Angina, Stable; Atrial Fibrillation; Coronary Stenosis; Myocardial Infarction; Myocardial Ischemia; Neoplasms; Tachycardia, Ventricular; Cardiovascular Diseases; Tachycardia, Paroxysmal; Wolff-Parkinson-White Syndrome Adenosine receptor agonist

Small molecule

Approved

OTHER

INJECTION; INTRAVENOUS

Inflammation; Ischemia; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Cardiomyopathies; Coronary Disease; Pain; Respiratory Distress Syndrome; ST Elevation Myocardial Infarction; Takotsubo Cardiomyopathy; Angina, Stable; Atrial Fibrillation; Coronary Stenosis; Myocardial Infarction; Myocardial Ischemia; Neoplasms; Tachycardia, Ventricular; Cardiovascular Diseases; Tachycardia, Paroxysmal; Wolff-Parkinson-White Syndrome

Adenosine receptor agonist


Small molecule Approved OTHER ORAL Neoplasms; Osteomyelitis; HIV Infections; Liver Abscess; Syphilis; Bacterial Infections; Bronchitis; Bronchitis, Chronic; Gonorrhea; Infections; Otitis Media; Pharyngitis; Tonsillitis; Urinary Tract Infections Bacterial penicillin-binding protein inhibitor


Small molecule Approved OTHER INJECTION; INTRAVENOUS; IV (INFUSION) Adenocarcinoma, Follicular; Adrenal Cortex Neoplasms; Anus Neoplasms; Appendiceal Neoplasms; Carcinoma, Renal Cell; Carcinoma, Verrucous; HIV Infections; Hypopharyngeal Neoplasms; Insulinoma; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Multiple Myeloma; Neoplasms, Cystic, Mucinous, and Serous; Neoplasms, Plasma Cell; Neuroendocrine Tumors; Parathyroid Neoplasms; Pericardial Effusion; Pleural Effusion; Skin Diseases; Somatostatinoma; Vaginal Neoplasms; Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Bile Duct Neoplasms; Bone Neoplasms; Brain Stem Neoplasms; Breast Neoplasms, Male; Burkitt Lymphoma; Carcinoid Tumor; Carcinoma, Endometrioid; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Islet Cell; Carcinoma, Merkel Cell; Carcinoma, Neuroendocrine; Carcinosarcoma; Cystadenoma, Serous; Gallbladder Neoplasms; Gastrointestinal Stromal Tumors; Gliosarcoma; Hereditary Breast and Ovarian Cancer Syndrome; Leiomyosarcoma; Leukemia; Leukemia, Myeloid, Acute; Lymphoma, B-Cell; Mesothelioma, Malignant; Myelodysplastic Syndromes; Myeloproliferative Disorders; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neoplasms, Complex and Mixed; Oligodendroglioma; Osteosarcoma; Pancreatic Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Retinal Neoplasms; Salivary Gland Neoplasms; Stomach Neoplasms; Thrombosis; Thymoma; Ureteral Neoplasms; Uveal Melanoma; Vulvar Neoplasms; Wilms Tumor; Adenocarcinoma of Lung; Anemia; Astrocytoma; Biliary Tract Neoplasms; Brain Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Cholangiocarcinoma; Choroid Plexus Neoplasms; Colorectal Neoplasms; Endometrial Neoplasms; Ependymoma; Esophageal Neoplasms; Fallopian Tube Neoplasms; Ganglioneuroblastoma; Genital Neoplasms, Female; Gestational Trophoblastic Disease; Glioblastoma; Glioma; Head and Neck Neoplasms; Hepatoblastoma; Hodgkin Disease; Inflammatory Breast Neoplasms; Kidney Neoplasms; Laryngeal Neoplasms; Leukemia-Lymphoma, Adult T-Cell; Liver Neoplasms; Lung Neoplasms; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Medulloblastoma; Melanoma; Mesothelioma; Mouth Neoplasms; Nasopharyngeal Carcinoma; Neoplasms, Germ Cell and Embryonal; Neuroblastoma; Neuroectodermal Tumors, Primitive; Oropharyngeal Neoplasms; Pain; Paraganglioma; Peripheral Nervous System Diseases; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Retinoblastoma; Retroviridae Infections; Sarcoma; Seminoma; Sex Cord-Gonadal Stromal Tumors; Skin Neoplasms; Small Cell Lung Carcinoma; Squamous Cell Carcinoma of Head and Neck; Testicular Neoplasms; Thyroid Neoplasms; Triple Negative Breast Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Carcinoma, Ovarian Epithelial; Neoplasms; Ovarian Neoplasms DNA inhibitor

Small molecule

Approved

OTHER

INJECTION; INTRAVENOUS; IV (INFUSION)

Adenocarcinoma, Follicular; Adrenal Cortex Neoplasms; Anus Neoplasms; Appendiceal Neoplasms; Carcinoma, Renal Cell; Carcinoma, Verrucous; HIV Infections; Hypopharyngeal Neoplasms; Insulinoma; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Multiple Myeloma; Neoplasms, Cystic, Mucinous, and Serous; Neoplasms, Plasma Cell; Neuroendocrine Tumors; Parathyroid Neoplasms; Pericardial Effusion; Pleural Effusion; Skin Diseases; Somatostatinoma; Vaginal Neoplasms; Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Bile Duct Neoplasms; Bone Neoplasms; Brain Stem Neoplasms; Breast Neoplasms, Male; Burkitt Lymphoma; Carcinoid Tumor; Carcinoma, Endometrioid; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Islet Cell; Carcinoma, Merkel Cell; Carcinoma, Neuroendocrine; Carcinosarcoma; Cystadenoma, Serous; Gallbladder Neoplasms; Gastrointestinal Stromal Tumors; Gliosarcoma; Hereditary Breast and Ovarian Cancer Syndrome; Leiomyosarcoma; Leukemia; Leukemia, Myeloid, Acute; Lymphoma, B-Cell; Mesothelioma, Malignant; Myelodysplastic Syndromes; Myeloproliferative Disorders; Nasopharyngeal Neoplasms; Neoplasm Metastasis; Neoplasms, Complex and Mixed; Oligodendroglioma; Osteosarcoma; Pancreatic Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prostatic Neoplasms; Retinal Neoplasms; Salivary Gland Neoplasms; Stomach Neoplasms; Thrombosis; Thymoma; Ureteral Neoplasms; Uveal Melanoma; Vulvar Neoplasms; Wilms Tumor; Adenocarcinoma of Lung; Anemia; Astrocytoma; Biliary Tract Neoplasms; Brain Neoplasms; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Central Nervous System Neoplasms; Cholangiocarcinoma; Choroid Plexus Neoplasms; Colorectal Neoplasms; Endometrial Neoplasms; Ependymoma; Esophageal Neoplasms; Fallopian Tube Neoplasms; Ganglioneuroblastoma; Genital Neoplasms, Female; Gestational Trophoblastic Disease; Glioblastoma; Glioma; Head and Neck Neoplasms; Hepatoblastoma; Hodgkin Disease; Inflammatory Breast Neoplasms; Kidney Neoplasms; Laryngeal Neoplasms; Leukemia-Lymphoma, Adult T-Cell; Liver Neoplasms; Lung Neoplasms; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Medulloblastoma; Melanoma; Mesothelioma; Mouth Neoplasms; Nasopharyngeal Carcinoma; Neoplasms, Germ Cell and Embryonal; Neuroblastoma; Neuroectodermal Tumors, Primitive; Oropharyngeal Neoplasms; Pain; Paraganglioma; Peripheral Nervous System Diseases; Peritoneal Neoplasms; Prostatic Neoplasms, Castration-Resistant; Retinoblastoma; Retroviridae Infections; Sarcoma; Seminoma; Sex Cord-Gonadal Stromal Tumors; Skin Neoplasms; Small Cell Lung Carcinoma; Squamous Cell Carcinoma of Head and Neck; Testicular Neoplasms; Thyroid Neoplasms; Triple Negative Breast Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Urogenital Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Carcinoma, Ovarian Epithelial; Neoplasms; Ovarian Neoplasms

DNA inhibitor


Small molecule Approved OTHER TRANSDERMAL Amphetamine-Related Disorders; Schizophrenia; Prostatic Neoplasms; Tobacco Use Disorder; Borderline Personality Disorder; Cocaine-Related Disorders; Depressive Disorder; Depressive Disorder, Major; Parkinson Disease Monoamine oxidase B inhibitor


Small molecule Approved OTHER ORAL Unknown Beta-1 adrenergic receptor antagonist


Small molecule Approved DERMATOLOGY; IMMUNE SYSTEM; OTHER TOPICAL Carcinoma, Squamous Cell; Condylomata Acuminata; Virus Diseases Unknown


Small molecule Approved ENT; EYE; OTHER; PEDIATRICS; PREGNANCY AND GYNECOLOGY INJECTION; OPHTHALMIC; ORAL; OTIC Hearing Loss; Osteomyelitis; Conjunctivitis, Bacterial; Diabetic Foot; Glaucoma; Glaucoma, Open-Angle; Ocular Hypertension; Otitis Media; Pelvic Inflammatory Disease; Urinary Tract Infections; Acne Vulgaris; Bacterial Infections; Bronchitis, Chronic; Corneal Ulcer; Eye Infections; Infections; Otitis Externa Bacterial DNA gyrase inhibitor

Small molecule

Approved

ENT; EYE; OTHER; PEDIATRICS; PREGNANCY AND GYNECOLOGY

INJECTION; OPHTHALMIC; ORAL; OTIC

Hearing Loss; Osteomyelitis; Conjunctivitis, Bacterial; Diabetic Foot; Glaucoma; Glaucoma, Open-Angle; Ocular Hypertension; Otitis Media; Pelvic Inflammatory Disease; Urinary Tract Infections; Acne Vulgaris; Bacterial Infections; Bronchitis, Chronic; Corneal Ulcer; Eye Infections; Infections; Otitis Externa

Bacterial DNA gyrase inhibitor


Small molecule Approved CARDIOVASCULAR; OTHER ORAL Opioid-Related Disorders; Smoking Cessation; Substance-Related Disorders; Tobacco Use Disorder; Bipolar Disorder; Parkinson Disease; Cardiovascular Diseases; Hypertension Voltage-gated L-type calcium channel blocker


Small molecule Approved OTHER INJECTION; ORAL Alzheimer Disease; Graft vs Host Disease; Leukemia, Myeloid, Acute; Lymphoma; Non-alcoholic Fatty Liver Disease; Pulmonary Disease, Chronic Obstructive; Respiratory Syncytial Virus Infections; Tinea Versicolor; Urinary Bladder, Overactive; Blastomycosis; Histoplasmosis; Intracranial Hypertension; Premature Birth; Sporotrichosis; Vulvovaginitis; Aspergillosis; Bacterial Infections; Candidemia; Candidiasis, Invasive; Candidiasis, Oral; Coccidioidomycosis; Crohn Disease; HIV Infections; Infections; Inflammatory Bowel Diseases; Leishmaniasis, Cutaneous; Leukopenia; Mycoses; Neoplasms; Tinea Pedis; Vaginal Discharge; Vaginitis; Vaginosis, Bacterial; Candidiasis; Candidiasis, Vulvovaginal; Meningitis, Cryptococcal; Urinary Tract Infections Cytochrome P450 51 inhibitor

Small molecule

Approved

OTHER

INJECTION; ORAL

Alzheimer Disease; Graft vs Host Disease; Leukemia, Myeloid, Acute; Lymphoma; Non-alcoholic Fatty Liver Disease; Pulmonary Disease, Chronic Obstructive; Respiratory Syncytial Virus Infections; Tinea Versicolor; Urinary Bladder, Overactive; Blastomycosis; Histoplasmosis; Intracranial Hypertension; Premature Birth; Sporotrichosis; Vulvovaginitis; Aspergillosis; Bacterial Infections; Candidemia; Candidiasis, Invasive; Candidiasis, Oral; Coccidioidomycosis; Crohn Disease; HIV Infections; Infections; Inflammatory Bowel Diseases; Leishmaniasis, Cutaneous; Leukopenia; Mycoses; Neoplasms; Tinea Pedis; Vaginal Discharge; Vaginitis; Vaginosis, Bacterial; Candidiasis; Candidiasis, Vulvovaginal; Meningitis, Cryptococcal; Urinary Tract Infections

Cytochrome P450 51 inhibitor


Protein Approved DIABETES DRUGS & ENDOCRINOLOGY; OTHER; PEDIATRICS INJECTION Unknown Growth hormone-releasing hormone receptor agonist


Small molecule Approved OTHER ORAL Lymphoma; Sarcoma; Neoplasms DNA inhibitor


Enzyme Approved OTHER INJECTION Severe Combined Immunodeficiency; Neoplasms 2'-deoxyadenosine hydrolytic enzyme


Small molecule Approved OTHER ORAL Sleep Wake Disorders; Sleep Initiation and Maintenance Disorders GABA-A receptor; anion channel positive allosteric modulator


Small molecule Approved OTHER INJECTION Unknown Muscle-type nicotinic acetylcholine receptor antagonist

Small molecule

Approved

EMERGENCY MEDICINE; GASTROINTESTINAL; OTHER

INJECTION; ORAL

Brain Diseases; Brain Injuries; Dyspnea; Lecithin Cholesterol Acyltransferase Deficiency; Neuralgia; Opioid-Related Disorders; Pruritus; Small Cell Lung Carcinoma; Amphetamine-Related Disorders; Breast Neoplasms; Cholecystitis; Cocaine-Related Disorders; Dementia; Gastroparesis; Glioma; Hallucinations; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Obsessive-Compulsive Disorder; Pancreatic Neoplasms; Sarcoma; Tobacco Use Disorder; Tonsillitis; Alcoholism; Gastroenteritis; Genital Neoplasms, Female; HIV Infections; Hypotension; Irritable Bowel Syndrome; Pain; Schizophrenia; Syncope; Uterine Cervical Neoplasms; Vomiting; Nausea; Neoplasms; Postoperative Nausea and Vomiting

Serotonin 3a (5-HT3a) receptor antagonist


Enzyme Approved OTHER INJECTION Unknown Glucocerebroside hydrolytic enzyme


Small molecule Approved OTHER ORAL Osteomyelitis; Bacterial Infections Bacterial penicillin-binding protein inhibitor


Small molecule Approved OTHER ORAL Fissure in Ano; Pregnancy; Vascular Diseases; Heart Failure; Hypertension; Oligohydramnios; Stroke; Fetal Membranes, Premature Rupture; Angina Pectoris; Cardiovascular Diseases; Coronary Artery Disease Soluble guanylate cyclase activator


Small molecule Approved OTHER ORAL Hepatolenticular Degeneration; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Asperger Syndrome; Autistic Disorder Lead chelating agent

Small molecule

Approved

IMMUNE SYSTEM; OTHER; RESPIRATORY

ORAL

Anovulation; Depressive Disorder, Major; HIV Infections; Neoplasm Metastasis; Neoplasms; Osteomyelitis; Parkinson Disease; Prostatic Neoplasms, Castration-Resistant; Venous Thromboembolism; Buruli Ulcer; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cystic Fibrosis; Disorders of Excessive Somnolence; Idiopathic Hypersomnia; Leukemia, Lymphocytic, Chronic, B-Cell; Lung Diseases; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Narcolepsy; Periodontitis; Pseudomyxoma Peritonei; Toxoplasmosis, Cerebral; Asthma; Bronchiolitis Obliterans; Bronchopulmonary Dysplasia; Crohn Disease; Gastritis; Heart Diseases; Helicobacter Infections; Hemorrhage; Lymphoma, Non-Hodgkin; Multiple Myeloma; Mycobacterium avium-intracellulare Infection; Pneumonia, Bacterial; Sepsis; Shock, Septic; Stomach Neoplasms; Stomach Ulcer; Tuberculosis; Bacterial Infections; Bronchitis, Chronic; Duodenal Ulcer; Infections; Maxillary Sinusitis; Otitis Media; Pharyngitis; Pneumonia; Sinusitis; Tonsillitis

Bacterial 70S ribosome inhibitor